Uterine Leiomyoma (Uterine Fibroids) - Pipeline Review, H2 2014

Published: Jul, 2014 | Pages: 96 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)

Uterine Leiomyoma (Uterine Fibroids) - Pipeline Review, H2 2014

Summary

Global Markets Direct's, 'Uterine Leiomyoma (Uterine Fibroids) - Pipeline Review, H2 2014', provides an overview of the Uterine Leiomyoma (Uterine Fibroids)'s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Uterine Leiomyoma (Uterine Fibroids), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Uterine Leiomyoma (Uterine Fibroids) and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Uterine Leiomyoma (Uterine Fibroids)
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in the therapeutics development for Uterine Leiomyoma (Uterine Fibroids) and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects 
- A review of the Uterine Leiomyoma (Uterine Fibroids) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Uterine Leiomyoma (Uterine Fibroids) pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Uterine Leiomyoma (Uterine Fibroids)
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Uterine Leiomyoma (Uterine Fibroids) pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

 Table of Contents
Table of Contents 2
List of Tables 5
List of Figures 6
Introduction 7
Global Markets Direct Report Coverage 7
Uterine Leiomyoma (Uterine Fibroids) Overview 8
Therapeutics Development 9
Pipeline Products for Uterine Leiomyoma (Uterine Fibroids) - Overview 9
Pipeline Products for Uterine Leiomyoma (Uterine Fibroids) - Comparative Analysis 10
Uterine Leiomyoma (Uterine Fibroids) - Therapeutics under Development by Companies 11
Uterine Leiomyoma (Uterine Fibroids) - Therapeutics under Investigation by Universities/Institutes 13
Uterine Leiomyoma (Uterine Fibroids) - Pipeline Products Glance 14
Late Stage Products 14
Clinical Stage Products 15
Early Stage Products 16
Uterine Leiomyoma (Uterine Fibroids) - Products under Development by Companies 17
Uterine Leiomyoma (Uterine Fibroids) - Products under Investigation by Universities/Institutes 18
Uterine Leiomyoma (Uterine Fibroids) - Companies Involved in Therapeutics Development 19
Euroscreen S.A. 19
Takeda Pharmaceutical Company Limited 20
Neurocrine Biosciences, Inc. 21
Novartis AG 22
Kissei Pharmaceutical Co., Ltd. 23
Bayer AG 24
BioSpecifics Technologies Corp. 25
Repros Therapeutics Inc. 26
Dongkook Pharmaceutical Co., Ltd. 27
HRA Pharma 28
AbbVie Inc. 29
Uterine Leiomyoma (Uterine Fibroids) - Therapeutics Assessment 30
Assessment by Monotherapy Products 30
Assessment by Target 31
Assessment by Mechanism of Action 33
Assessment by Route of Administration 35
Assessment by Molecule Type 37
Drug Profiles 39
ulipristal acetate - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
relugolix - Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
elagolix sodium - Drug Profile 42
Product Description 42
Mechanism of Action 42
R&D Progress 42
telapristone acetate - Drug Profile 44
Product Description 44
Mechanism of Action 44
R&D Progress 44
mifepristone - Drug Profile 47
Product Description 47
Mechanism of Action 47
R&D Progress 47
KLH-2109 - Drug Profile 48
Product Description 48
Mechanism of Action 48
R&D Progress 48
vilaprisan - Drug Profile 49
Product Description 49
Mechanism of Action 49
R&D Progress 49
ESN-364 - Drug Profile 50
Product Description 50
Mechanism of Action 50
R&D Progress 50
LFA-102 - Drug Profile 51
Product Description 51
Mechanism of Action 51
R&D Progress 51
collagenase clostridium histolyticum - Drug Profile 53
Product Description 53
Mechanism of Action 53
R&D Progress 53
GnRH Antagonists - Drug Profile 57
Product Description 57
Mechanism of Action 57
R&D Progress 57
EVE-104 - Drug Profile 58
Product Description 58
Mechanism of Action 58
R&D Progress 58
triptorelin pamoate biosimilar - Drug Profile 59
Product Description 59
Mechanism of Action 59
R&D Progress 59
Drug to Activate Progesterone Receptor for Uterine Fibroids - Drug Profile 60
Product Description 60
Mechanism of Action 60
R&D Progress 60
Drugs for Women Health - Drug Profile 61
Product Description 61
Mechanism of Action 61
R&D Progress 61
Uterine Leiomyoma (Uterine Fibroids) - Recent Pipeline Updates 62
Uterine Leiomyoma (Uterine Fibroids) - Dormant Projects 83
Uterine Leiomyoma (Uterine Fibroids) - Discontinued Products 84
Uterine Leiomyoma (Uterine Fibroids) - Product Development Milestones 85
Featured News & Press Releases 85
Mar 27, 2013: Neurocrine Biosciences Initiates Phase IIb Study Of Elagolix For Treatment Of Uterine Fibroids 85
Feb 28, 2013: Repros Announces FDA Grants End Of Phase II Meeting To Discuss Proellex-V Phase III Study Design 85
Jan 03, 2013: Repros Reports Positive Topline Results From Phase II Study Of Proellex-V For Treatment Of Uterine Fibroids 85
Jul 30, 2012: FDA Schedules Meeting With Repros To Discuss Phase II Protocol For Proellex For Treatment Of Endometriosis 87
Jul 23, 2012: Repros's Proellex-V Shows Consistent Efficacy In Phase II Study Of Uterine Fibroids 87
Apr 30, 2012: Repros's Proellex-V Clears Hurdle In Uterine Fibroid Program 88
Mar 12, 2012: Watson Initiates US Phase III Clinical Trial Of Esmya 89
Feb 27, 2012: HRA Pharma's Esmya Receives European Commission Marketing Authorization For Pre-Operative Treatment Of Uterine Fibroids 90
Feb 02, 2012: PregLem Announces Full Results Of PEARL I And II Studies Of Esmya Published In New England Journal Of Medicine 91
Jan 04, 2012: FDA Accepts Repros's Investigational New Drug Application For Proellex-V For Treatment Of Uterine Fibroids 93
Appendix 95
Methodology 95
Coverage 95
Secondary Research 95
Primary Research 95
Expert Panel Validation 95
Contact Us 96
Disclaimer 96

List of Tables
Number of Products under Development for Uterine Leiomyoma (Uterine Fibroids), H2 2014 9
Number of Products under Development for Uterine Leiomyoma (Uterine Fibroids) - Comparative Analysis, H2 2014 10
Number of Products under Development by Companies, H2 2014 12
Number of Products under Investigation by Universities/Institutes, H2 2014 13
Comparative Analysis by Late Stage Development, H2 2014 14
Comparative Analysis by Clinical Stage Development, H2 2014 15
Comparative Analysis by Early Stage Development, H2 2014 16
Products under Development by Companies, H2 2014 17
Products under Investigation by Universities/Institutes, H2 2014 18
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by Euroscreen S.A., H2 2014 19
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by Takeda Pharmaceutical Company Limited, H2 2014 20
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by Neurocrine Biosciences, Inc., H2 2014 21
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by Novartis AG, H2 2014 22
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by Kissei Pharmaceutical Co., Ltd., H2 2014 23
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by Bayer AG, H2 2014 24
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by BioSpecifics Technologies Corp., H2 2014 25
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by Repros Therapeutics Inc., H2 2014 26
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by Dongkook Pharmaceutical Co., Ltd., H2 2014 27
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by HRA Pharma, H2 2014 28
Uterine Leiomyoma (Uterine Fibroids) - Pipeline by AbbVie Inc., H2 2014 29
Assessment by Monotherapy Products, H2 2014 30
Number of Products by Stage and Target, H2 2014 32
Number of Products by Stage and Mechanism of Action, H2 2014 34
Number of Products by Stage and Route of Administration, H2 2014 36
Number of Products by Stage and Molecule Type, H2 2014 38
Uterine Leiomyoma (Uterine Fibroids) Therapeutics - Recent Pipeline Updates, H2 2014 62
Uterine Leiomyoma (Uterine Fibroids) - Dormant Projects, H2 2014 83
Uterine Leiomyoma (Uterine Fibroids) - Discontinued Products, H2 2014 84