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Published: Dec, 2014 | Pages:
142 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline Review, H2 2014', provides an overview of the Transitional Cell Cancer (Urothelial Cell Cancer)'s therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Transitional Cell Cancer (Urothelial Cell Cancer), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Transitional Cell Cancer (Urothelial Cell Cancer) and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Transitional Cell Cancer (Urothelial Cell Cancer) - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Transitional Cell Cancer (Urothelial Cell Cancer) and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Transitional Cell Cancer (Urothelial Cell Cancer) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Transitional Cell Cancer (Urothelial Cell Cancer) pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Transitional Cell Cancer (Urothelial Cell Cancer) - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Transitional Cell Cancer (Urothelial Cell Cancer) pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Transitional Cell Cancer (Urothelial Cell Cancer) Overview 9 Therapeutics Development 10 Pipeline Products for Transitional Cell Cancer (Urothelial Cell Cancer) - Overview 10 Pipeline Products for Transitional Cell Cancer (Urothelial Cell Cancer) - Comparative Analysis 11 Transitional Cell Cancer (Urothelial Cell Cancer) - Therapeutics under Development by Companies 12 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline Products Glance 14 Late Stage Products 14 Clinical Stage Products 15 Early Stage Products 16 Transitional Cell Cancer (Urothelial Cell Cancer) - Products under Development by Companies 17 Transitional Cell Cancer (Urothelial Cell Cancer) - Companies Involved in Therapeutics Development 19 Altor BioScience Corporation 19 Astellas Pharma Inc. 20 AstraZeneca PLC 21 Boston Biomedical, Inc. 22 Daiichi Sankyo Company, Limited 23 Dendreon Corporation 24 Eli Lilly and Company 25 Exelixis, Inc. 26 GlaxoSmithKline plc 27 Innate Therapeutics Limited 28 Merck & Co., Inc. 29 Merck KGaA 30 Mirati Therapeutics Inc. 31 Novartis AG 32 Sanofi 33 Sumitomo Dainippon Pharma Co., Ltd. 34 Teva Pharmaceutical Industries Limited 35 TRACON Pharmaceuticals, Inc. 36 Transitional Cell Cancer (Urothelial Cell Cancer) - Therapeutics Assessment 37 Assessment by Monotherapy Products 37 Assessment by Target 38 Assessment by Mechanism of Action 41 Assessment by Route of Administration 43 Assessment by Molecule Type 45 Drug Profiles 47 AGS-15E - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 ALT-801 - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 amrubicin hydrochloride - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 ASG-15ME - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 AZD-4547 - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 BBI-503 - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 buparlisib hydrochloride - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 cabazitaxel - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 cabozantinib s-malate - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 CEP-11981 - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 dovitinib lactate - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 enfortumab vedotin - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 lapuleucel-t - Drug Profile 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 MIS-416 - Drug Profile 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 mocetinostat - Drug Profile 78 Product Description 78 Mechanism of Action 78 R&D Progress 78 MSB-0010718C - Drug Profile 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 pembrolizumab - Drug Profile 82 Product Description 82 Mechanism of Action 82 R&D Progress 82 ramucirumab - Drug Profile 86 Product Description 86 Mechanism of Action 86 R&D Progress 86 SAR-408701 - Drug Profile 91 Product Description 91 Mechanism of Action 91 R&D Progress 91 SNX-5422 - Drug Profile 92 Product Description 92 Mechanism of Action 92 R&D Progress 92 tigatuzumab - Drug Profile 94 Product Description 94 Mechanism of Action 94 R&D Progress 94 trametinib dimethyl sulfoxide - Drug Profile 96 Product Description 96 Mechanism of Action 96 R&D Progress 96 TRC-105 - Drug Profile 99 Product Description 99 Mechanism of Action 99 R&D Progress 99 Transitional Cell Cancer (Urothelial Cell Cancer) - Recent Pipeline Updates 101 Transitional Cell Cancer (Urothelial Cell Cancer) - Dormant Projects 135 Transitional Cell Cancer (Urothelial Cell Cancer) - Discontinued Products 137 Transitional Cell Cancer (Urothelial Cell Cancer) - Product Development Milestones 138 Featured News & Press Releases 138 May 14, 2014: Dendreon Announces Presentation of DN24-02 Immuno-Oncology Data at the 2014 ASCO Annual Meeting 138 Jan 30, 2014: Dendreon Announces Presentation of DN24-02 Data at the 2014 Genitourinary Cancer Symposium 138 May 31, 2013: Dendreon Announces Presentation Of DN24-02 Data At 2013 ASCO Annual Meeting 139 May 07, 2013: Exelixis To Feature Nine Presentations On Cabozantinib At 2013 ASCO Annual Meeting 139 Appendix 141 Methodology 141 Coverage 141 Secondary Research 141 Primary Research 141 Expert Panel Validation 141 Contact Us 142 Disclaimer 142
List of Tables Number of Products under Development for Transitional Cell Cancer (Urothelial Cell Cancer), H2 2014 10 Number of Products under Development for Transitional Cell Cancer (Urothelial Cell Cancer) - Comparative Analysis, H2 2014 11 Number of Products under Development by Companies, H2 2014 12 Comparative Analysis by Late Stage Development, H2 2014 14 Comparative Analysis by Clinical Stage Development, H2 2014 15 Comparative Analysis by Early Stage Development, H2 2014 16 Products under Development by Companies, H2 2014 17 Products under Development by Companies, H2 2014 (Contd..1) 18 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Altor BioScience Corporation, H2 2014 19 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Astellas Pharma Inc., H2 2014 20 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by AstraZeneca PLC, H2 2014 21 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Boston Biomedical, Inc., H2 2014 22 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Daiichi Sankyo Company, Limited, H2 2014 23 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Dendreon Corporation, H2 2014 24 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Eli Lilly and Company, H2 2014 25 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Exelixis, Inc., H2 2014 26 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by GlaxoSmithKline plc, H2 2014 27 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Innate Therapeutics Limited, H2 2014 28 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Merck & Co., Inc., H2 2014 29 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Merck KGaA, H2 2014 30 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Mirati Therapeutics Inc., H2 2014 31 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Novartis AG, H2 2014 32 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Sanofi, H2 2014 33 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Sumitomo Dainippon Pharma Co., Ltd., H2 2014 34 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by Teva Pharmaceutical Industries Limited, H2 2014 35 Transitional Cell Cancer (Urothelial Cell Cancer) - Pipeline by TRACON Pharmaceuticals, Inc., H2 2014 36 Assessment by Monotherapy Products, H2 2014 37 Number of Products by Stage and Target, H2 2014 39 Number of Products by Stage and Mechanism of Action, H2 2014 42 Number of Products by Stage and Route of Administration, H2 2014 44 Number of Products by Stage and Molecule Type, H2 2014 46 Transitional Cell Cancer (Urothelial Cell Cancer) Therapeutics - Recent Pipeline Updates, H2 2014 101 Transitional Cell Cancer (Urothelial Cell Cancer) - Dormant Projects, H2 2014 135 Transitional Cell Cancer (Urothelial Cell Cancer) - Dormant Projects (Contd..1), H2 2014 136 Transitional Cell Cancer (Urothelial Cell Cancer) - Discontinued Products, H2 2014 137
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