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Published: Sep, 2014 | Pages:
67 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Tinnitus - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Tinnitus - Pipeline Review, H2 2014', provides an overview of the Tinnitus's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Tinnitus, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Tinnitus and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Tinnitus - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Tinnitus and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Tinnitus products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Tinnitus pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Tinnitus - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Tinnitus pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Tinnitus Overview 7 Therapeutics Development 8 Pipeline Products for Tinnitus - Overview 8 Pipeline Products for Tinnitus - Comparative Analysis 9 Tinnitus - Therapeutics under Development by Companies 10 Tinnitus - Therapeutics under Investigation by Universities/Institutes 11 Tinnitus - Pipeline Products Glance 12 Late Stage Products 12 Clinical Stage Products 13 Early Stage Products 14 Unknown Stage Products 15 Tinnitus - Products under Development by Companies 16 Tinnitus - Products under Investigation by Universities/Institutes 17 Tinnitus - Companies Involved in Therapeutics Development 18 Merz Pharma GmbH & Co. KgaA 18 Auris Medical Holding AG 19 Knopp Biosciences LLC 20 Otonomy, Inc. 21 Sound Pharmaceuticals, Inc. 22 Synphora AB 23 Flexion Therapeutics, Inc. 24 Autifony Therapeutics Limited 25 AudioCure Pharma GmbH 26 Tinnitus - Therapeutics Assessment 27 Assessment by Monotherapy Products 27 Assessment by Target 28 Assessment by Mechanism of Action 30 Assessment by Route of Administration 32 Assessment by Molecule Type 34 Drug Profiles 35 neramexane mesylate - Drug Profile 35 Product Description 35 Mechanism of Action 35 R&D Progress 35 esketamine hydrochloride - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 latanoprost - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 SPI-1005 - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 SPI-3005 - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 AUT-00063 - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 gacyclidine - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 AUT-3 - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 acamprosate - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 Small Molecules to Activate Kv7 for Neuropathic Pain, Epilepsy and Tinnitus - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 AM-102 - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 Drug to Activate KCNQ for Tinnitus - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 Small Molecules for Tinnitus - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 Drug For Tinnitus - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 Tinnitus - Recent Pipeline Updates 53 Tinnitus - Dormant Projects 57 Tinnitus - Product Development Milestones 58 Featured News & Press Releases 58 Jun 04, 2014: Autifony Therapeutics awarded �2.2 million to progress first-in-class drug for tinnitus into Phase IIa study 58 Mar 31, 2014: Published Analysis Confirms Positive Results from Auris Medical's Phase IIb Study with AM-101 in Treatment of Acute Inner Ear Tinnitus 58 Sep 09, 2013: Second Phase II Clinical Trial Confirms Safety and Efficacy Trends for Auris Medical AG's AM-101 in Treatment of Acute Peripheral Tinnitus 60 Jun 04, 2013: Autifony Therapeutics Initiates Phase I Trial Of AUT-00063 For Treatment Of Hearing Loss And Tinnitus 61 May 17, 2013: Auris Medical Announces Presentation Of Safety Results From AM-101 Clinical Development At 7th International TRI Tinnitus Conference 61 Apr 30, 2013: Auris Medical Selects Medidata Clinical Cloud To Support New Tinnitus Research 62 Feb 12, 2013: Auris Medical Completes Enrollment In Phase II Study Of AM-101 For Treatment Of Acute Peripheral Tinnitus 63 Aug 10, 2012: Auris Medical Completes Enrolment In First Stage Of AM-101 TACTT1 Study 63 Jun 26, 2012: Auris Medical Presents Key Results From Phase IIb Study Of AM-101 At International TRI Tinnitus Conference 63 Oct 17, 2011: Auris Medical Reports Positive Results From Phase IIb Trial With AM-101 For Treatment Of Acute Inner Ear Tinnitus 65 Appendix 66 Methodology 66 Coverage 66 Secondary Research 66 Primary Research 66 Expert Panel Validation 66 Contact Us 67 Disclaimer 67
List of Tables Number of Products under Development for Tinnitus, H2 2014 8 Number of Products under Development for Tinnitus - Comparative Analysis, H2 2014 9 Number of Products under Development by Companies, H2 2014 10 Number of Products under Investigation by Universities/Institutes, H2 2014 11 Comparative Analysis by Late Stage Development, H2 2014 12 Comparative Analysis by Clinical Stage Development, H2 2014 13 Comparative Analysis by Early Stage Development, H2 2014 14 Comparative Analysis by Unknown Stage Development, H2 2014 15 Products under Development by Companies, H2 2014 16 Products under Investigation by Universities/Institutes, H2 2014 17 Tinnitus - Pipeline by Merz Pharma GmbH & Co. KgaA, H2 2014 18 Tinnitus - Pipeline by Auris Medical Holding AG, H2 2014 19 Tinnitus - Pipeline by Knopp Biosciences LLC, H2 2014 20 Tinnitus - Pipeline by Otonomy, Inc., H2 2014 21 Tinnitus - Pipeline by Sound Pharmaceuticals, Inc., H2 2014 22 Tinnitus - Pipeline by Synphora AB., H2 2014 23 Tinnitus - Pipeline by Flexion Therapeutics, Inc., H2 2014 24 Tinnitus - Pipeline by Autifony Therapeutics Limited, H2 2014 25 Tinnitus - Pipeline by AudioCure Pharma GmbH, H2 2014 26 Assessment by Monotherapy Products, H2 2014 27 Number of Products by Stage and Target, H2 2014 29 Number of Products by Stage and Mechanism of Action, H2 2014 31 Number of Products by Stage and Route of Administration, H2 2014 33 Number of Products by Stage and Molecule Type, H2 2014 34 Tinnitus Therapeutics - Recent Pipeline Updates, H2 2014 53 Tinnitus - Dormant Projects, H2 2014 57
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