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Published: Feb, 2016 | Pages:
103 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Thromboembolism - Pipeline Review, H1 2016 Summary
Global Markets Direct's, 'Thromboembolism - Pipeline Review, H1 2016', provides an overview of the Thromboembolism pipeline landscape. The report provides comprehensive information on the therapeutics under development for Thromboembolism, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Thromboembolism and features dormant and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data. Scope - The report provides a snapshot of the global therapeutic landscape of Thromboembolism - The report reviews pipeline therapeutics for Thromboembolism by companies and universities/research institutes based on information derived from company and industry-specific sources - The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages - The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved Thromboembolism therapeutics and enlists all their major and minor projects - The report assesses Thromboembolism therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type - The report summarizes all the dormant and discontinued pipeline projects - The report reviews latest news related to pipeline therapeutics for Thromboembolism Reasons to buy
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Identify and understand important and diverse types of therapeutics under development for Thromboembolism - Identify potential new clients or partners in the target demographic - Develop strategic initiatives by understanding the focus areas of leading companies - Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics - Devise corrective measures for pipeline projects by understanding Thromboembolism pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents
Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Thromboembolism Overview 9 Therapeutics Development 10 Pipeline Products for Thromboembolism - Overview 10 Pipeline Products for Thromboembolism - Comparative Analysis 11 Thromboembolism - Therapeutics under Development by Companies 12 Thromboembolism - Therapeutics under Investigation by Universities/Institutes 13 Thromboembolism - Pipeline Products Glance 14 Late Stage Products 14 Clinical Stage Products 15 Early Stage Products 16 Thromboembolism - Products under Development by Companies 17 Thromboembolism - Products under Investigation by Universities/Institutes 18 Thromboembolism - Companies Involved in Therapeutics Development 19 Bayer AG 19 Cereno Scientific AB 20 China Biologic Products, Inc. 21 Daiichi Sankyo Company, Limited 22 F. Hoffmann-La Roche Ltd. 23 Gamma Therapeutics, Inc. 24 GlycoMimetics, Inc. 25 Green Cross Corporation 26 Ionis Pharmaceuticals, Inc. 27 Portola Pharmaceuticals, Inc. 28 Sanofi 29 The International Biotechnology Center (IBC) Generium 30 Thromboembolism - Therapeutics Assessment 31 Assessment by Monotherapy Products 31 Assessment by Target 32 Assessment by Mechanism of Action 34 Assessment by Route of Administration 36 Assessment by Molecule Type 38 Drug Profiles 40 alteplase biosimilar - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 antithrombin III (human) - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 betrixaban - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 C-3 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 CS-1 - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 edoxaban tosylate - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 Gammarin - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 GCC-2107 - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 GMI-1271 - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 ISIS-FXIRx - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 Lysimab - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 Peptide to Inhibit PAI-1 for Arterial Thrombosis and Pulmonary Thromboembolism - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 Protein for Thromboembolism - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 rivaroxaban - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 semuloparin sodium - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 TAP-ANV - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 TRX-1 - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 YG-001 - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 Thromboembolism - Recent Pipeline Updates 66 Thromboembolism - Dormant Projects 89 Thromboembolism - Discontinued Products 90 Thromboembolism - Product Development Milestones 91 Featured News & Press Releases 91 Dec 07, 2015: First Data Unveiled from CALLISTO Program Examining the Use of XARELTO (rivaroxaban) for Treating Blood Clots in People with Cancer 91 Nov 30, 2015: New Data from Bayer's Portfolio in Thrombosis to be Presented at ASH 2015 93 Nov 06, 2015: Bristol-Myers Squibb and Pfizer to Present New Data on Eliquis (apixaban) at the American Heart Association Scientific Sessions 2015 93 Oct 30, 2015: Portola Pharmaceuticals Completes Enrollment in Pivotal Phase 3 APEX Study of Betrixaban for Prevention of Blood Clots in Acute Medically IllPatients 96 Oct 30, 2015: Isis Pharmaceuticals Initiates Phase 2 Study of ISIS-FXI Rx in Patients with End-Stage Renal Disease on Hemodialysis 97 Oct 13, 2015: Portola Pharmaceuticals Announces FDA Grants Fast Track Designation to Betrixaban for Prevention of Blood Clots in Acute Medically Ill Patients 97 Sep 24, 2015: Bayer's Xarelto Approved in Japan for the Treatment and Secondary Prevention of Pulmonary Thromboembolism and Deep Vein Thrombosis 98 Sep 24, 2015: Bayer's Xarelto Approved in Japan for the Treatment and Secondary Prevention of Pulmonary Thromboembolism and Deep Vein Thrombosis 99 Jul 12, 2015: NICE recommends edoxaban tosylate (Lixiana) for treating and preventing potentially fatal blood clots 99 Jun 18, 2015: Daiichi Sankyo Initiates Hokusai-VTE Cancer Study to Evaluate the Role of Edoxaban in Patients with Venous Thromboembolism Associated with Cancer 100 Appendix 102 Methodology 102 Coverage 102 Secondary Research 102 Primary Research 102 Expert Panel Validation 102 Contact Us 102 Disclaimer 103
List of Tables
Number of Products under Development for Thromboembolism, H1 2016 10 Number of Products under Development for Thromboembolism - Comparative Analysis, H1 2016 11 Number of Products under Development by Companies, H1 2016 12 Number of Products under Investigation by Universities/Institutes, H1 2016 13 Comparative Analysis by Late Stage Development, H1 2016 14 Comparative Analysis by Clinical Stage Development, H1 2016 15 Comparative Analysis by Early Stage Development, H1 2016 16 Products under Development by Companies, H1 2016 17 Products under Investigation by Universities/Institutes, H1 2016 18 Thromboembolism - Pipeline by Bayer AG, H1 2016 19 Thromboembolism - Pipeline by Cereno Scientific AB, H1 2016 20 Thromboembolism - Pipeline by China Biologic Products, Inc., H1 2016 21 Thromboembolism - Pipeline by Daiichi Sankyo Company, Limited, H1 2016 22 Thromboembolism - Pipeline by F. Hoffmann-La Roche Ltd., H1 2016 23 Thromboembolism - Pipeline by Gamma Therapeutics, Inc., H1 2016 24 Thromboembolism - Pipeline by GlycoMimetics, Inc., H1 2016 25 Thromboembolism - Pipeline by Green Cross Corporation, H1 2016 26 Thromboembolism - Pipeline by Ionis Pharmaceuticals, Inc., H1 2016 27 Thromboembolism - Pipeline by Portola Pharmaceuticals, Inc., H1 2016 28 Thromboembolism - Pipeline by Sanofi, H1 2016 29 Thromboembolism - Pipeline by The International Biotechnology Center (IBC) Generium, H1 2016 30 Assessment by Monotherapy Products, H1 2016 31 Number of Products by Stage and Target, H1 2016 33 Number of Products by Stage and Mechanism of Action, H1 2016 35 Number of Products by Stage and Route of Administration, H1 2016 37 Number of Products by Stage and Molecule Type, H1 2016 39 Thromboembolism Therapeutics - Recent Pipeline Updates, H1 2016 66 Thromboembolism - Dormant Projects, H1 2016 89 Thromboembolism - Discontinued Products, H1 2016 90
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