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Published: Jul, 2014 | Pages:
88 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Substance (Drug) Abuse - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Substance (Drug) Abuse - Pipeline Review, H2 2014', provides an overview of the Substance (Drug) Abuse's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Substance (Drug) Abuse, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Substance (Drug) Abuse and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Substance (Drug) Abuse - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Substance (Drug) Abuse and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Substance (Drug) Abuse products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Substance (Drug) Abuse pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Substance (Drug) Abuse - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Substance (Drug) Abuse pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Substance (Drug) Abuse Overview 9 Therapeutics Development 10 Pipeline Products for Substance (Drug) Abuse - Overview 10 Pipeline Products for Substance (Drug) Abuse - Comparative Analysis 11 Substance (Drug) Abuse - Therapeutics under Development by Companies 12 Substance (Drug) Abuse - Therapeutics under Investigation by Universities/Institutes 14 Substance (Drug) Abuse - Pipeline Products Glance 16 Late Stage Products 16 Clinical Stage Products 17 Early Stage Products 18 Substance (Drug) Abuse - Products under Development by Companies 19 Substance (Drug) Abuse - Products under Investigation by Universities/Institutes 20 Substance (Drug) Abuse - Companies Involved in Therapeutics Development 21 Teva Pharmaceutical Industries Limited 21 Addex Therapeutics Ltd 22 Snowdon Inc. 23 Grunenthal GmbH 24 Charleston Laboratories, Inc. 25 Reckitt Benckiser Pharmaceutical, Inc. 26 AllTranz, Inc. 27 InterveXion Therapeutics LLC 28 P2D Bioscience 29 Foresee Pharmaceuticals, LLC 30 Substance (Drug) Abuse - Therapeutics Assessment 31 Assessment by Monotherapy Products 31 Assessment by Target 32 Assessment by Mechanism of Action 35 Assessment by Route of Administration 38 Assessment by Molecule Type 40 Drug Profiles 42 Icariin - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 L-Tetrahydropalmatine - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 RBP-8000 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 hydrocodone bitartrate ER - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 Ch-mAb7F9 - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 ADX-88178 - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 ADX-71441 - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 Small Molecules for Neurological Disorders - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 ADX-71743 - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 Vaccine for Drug Abuse - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 Small Molecules to Inhibit DAT for Cocaine Addiction and Cocaine Abuse - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 Enzyme for Cocaine Addiction - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 Vaccine for Methamphetamine Abuse - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 dronabinol - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 CLBPC - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 CLFTC - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 CLHMC - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 CLOXC - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 CLHDC - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 Small Molecules to Inhibit Dopamine Transporter for CNS and Metabolic Disorders - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 VU-0463841 - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 RO-656570 - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 2E2 - Drug Profile 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 FP-004 - Drug Profile 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 Small Molecule to Inhibit CB1 Receptor for Cannabinoid Abuse and Drug Addiction - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 Drug to Inhibit Mu Opioid Receptor for Drug Abuse and Alcohol Addiction - Drug Profile 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 Substance (Drug) Abuse - Recent Pipeline Updates 73 Substance (Drug) Abuse - Dormant Projects 78 Substance (Drug) Abuse - Product Development Milestones 79 Featured News & Press Releases 79 Jul 08, 2014: FDA Grants Priority Review Designation for Purdue Pharma's Once-Daily Hydrocodone Bitartrate Extended-Release Tablets Formulated with Abuse-Deterrent Properties 79 Apr 30, 2014: Purdue Pharma Submits NDA For Once-Daily Hydrocodone Bitartrate Extended-Release Tablets Formulated To Incorporate Abuse-Deterrent Properties 79 Jul 29, 2013: Signature Therapeutics Receives BrIDGs Award to Advance Its Abuse-Deterrent Oxycodone, PF614 81 Jun 17, 2013: Purdue Pharma Announces Presentation Of Poster On OxyContin At 75th CPDD Annual Meeting 82 Dec 20, 2012: Acura Pharma Submits Investigational New Drug Application 82 Dec 20, 2012: Addex Scientists Discover And Characterize First Potent And Selective Small Molecule Negative Allosteric Modulator Targeting mGlu7 Receptor 83 Oct 29, 2012: Addex Therapeutics Announces Positive Preclinical Data For ADX71441 For Treatment Of Alcoholism 84 Mar 29, 2011: Catalyst Announces Commencement Of CPP-109 Investigator-Sponsored Study In Cocaine And Alcohol Co-Dependent Patients 84 Mar 09, 2011: MediciNova Receives Notice Of Allowance For Method Of Treating Drug Addiction 85 Dec 09, 2010: Catalyst Reports Canadian Patent For CPP-109 For Prevention Of Addiction In Pain Management 86 Appendix 87 Methodology 87 Coverage 87 Secondary Research 87 Primary Research 87 Expert Panel Validation 87 Contact Us 88 Disclaimer 88
List of Tables Number of Products under Development for Substance (Drug) Abuse, H2 2014 10 Number of Products under Development for Substance (Drug) Abuse - Comparative Analysis, H2 2014 11 Number of Products under Development by Companies, H2 2014 13 Number of Products under Investigation by Universities/Institutes, H2 2014 15 Comparative Analysis by Late Stage Development, H2 2014 16 Comparative Analysis by Clinical Stage Development, H2 2014 17 Comparative Analysis by Early Stage Development, H2 2014 18 Products under Development by Companies, H2 2014 19 Products under Investigation by Universities/Institutes, H2 2014 20 Substance (Drug) Abuse - Pipeline by Teva Pharmaceutical Industries Limited, H2 2014 21 Substance (Drug) Abuse - Pipeline by Addex Therapeutics Ltd, H2 2014 22 Substance (Drug) Abuse - Pipeline by Snowdon Inc., H2 2014 23 Substance (Drug) Abuse - Pipeline by Grunenthal GmbH, H2 2014 24 Substance (Drug) Abuse - Pipeline by Charleston Laboratories, Inc., H2 2014 25 Substance (Drug) Abuse - Pipeline by Reckitt Benckiser Pharmaceutical, Inc., H2 2014 26 Substance (Drug) Abuse - Pipeline by AllTranz, Inc., H2 2014 27 Substance (Drug) Abuse - Pipeline by InterveXion Therapeutics LLC, H2 2014 28 Substance (Drug) Abuse - Pipeline by P2D Bioscience, H2 2014 29 Substance (Drug) Abuse - Pipeline by Foresee Pharmaceuticals, LLC, H2 2014 30 Assessment by Monotherapy Products, H2 2014 31 Number of Products by Stage and Target, H2 2014 34 Number of Products by Stage and Mechanism of Action, H2 2014 37 Number of Products by Stage and Route of Administration, H2 2014 39 Number of Products by Stage and Molecule Type, H2 2014 41 Substance (Drug) Abuse Therapeutics - Recent Pipeline Updates, H2 2014 73 Substance (Drug) Abuse - Dormant Projects, H2 2014 78
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