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Published: Jul, 2014 | Pages:
123 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Squamous Non-Small Cell Lung Cancer - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Squamous Non-Small Cell Lung Cancer - Pipeline Review, H2 2014', provides an overview of the Squamous Non-Small Cell Lung Cancer's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Squamous Non-Small Cell Lung Cancer, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Squamous Non-Small Cell Lung Cancer and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Squamous Non-Small Cell Lung Cancer - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Squamous Non-Small Cell Lung Cancer and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Squamous Non-Small Cell Lung Cancer products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Squamous Non-Small Cell Lung Cancer pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Squamous Non-Small Cell Lung Cancer - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Squamous Non-Small Cell Lung Cancer pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Squamous Non-Small Cell Lung Cancer Overview 8 Therapeutics Development 9 Pipeline Products for Squamous Non-Small Cell Lung Cancer - Overview 9 Pipeline Products for Squamous Non-Small Cell Lung Cancer - Comparative Analysis 10 Squamous Non-Small Cell Lung Cancer - Therapeutics under Development by Companies 11 Squamous Non-Small Cell Lung Cancer - Pipeline Products Glance 13 Late Stage Products 13 Clinical Stage Products 14 Squamous Non-Small Cell Lung Cancer - Products under Development by Companies 15 Squamous Non-Small Cell Lung Cancer - Companies Involved in Therapeutics Development 16 Bristol-Myers Squibb Company 16 Johnson & Johnson 17 Boehringer Ingelheim GmbH 18 AstraZeneca PLC 19 Eli Lilly and Company 20 Novartis AG 21 Eisai Co., Ltd. 22 Ono Pharmaceutical Co., Ltd. 23 Vertex Pharmaceuticals Incorporated 24 Celgene Corporation 25 Bayer AG 26 Oncogenex Pharmaceuticals, Inc. 27 Ascenta Therapeutics, Inc. 28 Five Prime Therapeutics, Inc. 29 Advenchen Laboratories, LLC 30 AbbVie Inc. 31 Squamous Non-Small Cell Lung Cancer - Therapeutics Assessment 32 Assessment by Monotherapy Products 32 Assessment by Target 33 Assessment by Mechanism of Action 36 Assessment by Route of Administration 39 Assessment by Molecule Type 41 Drug Profiles 43 ipilimumab - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 necitumumab - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 paclitaxel - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 veliparib - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 nivolumab - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 lenvatinib - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 apatorsen - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 buparlisib hydrochloride - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 LY-2606368 - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 lucitanib - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 VX-970 - Drug Profile 69 Product Description 69 Mechanism of Action 69 R&D Progress 69 nintedanib - Drug Profile 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 JNJ-42756493 - Drug Profile 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 FP-1039 - Drug Profile 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 AT-406 - Drug Profile 77 Product Description 77 Mechanism of Action 77 R&D Progress 77 AZD-8186 - Drug Profile 80 Product Description 80 Mechanism of Action 80 R&D Progress 80 BAY-1163877 - Drug Profile 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 Squamous Non-Small Cell Lung Cancer - Recent Pipeline Updates 82 Squamous Non-Small Cell Lung Cancer - Dormant Projects 113 Squamous Non-Small Cell Lung Cancer - Discontinued Products 114 Squamous Non-Small Cell Lung Cancer - Product Development Milestones 115 Featured News & Press Releases 115 Jul 01, 2014: OncoGenex Announces Cedar Clinical Trial Evaluating Apatorsen in Combination with Chemotherapy in Advanced Squamous Cell Lung Cancer is Now Open for Enrollment 115 May 15, 2014: English Court Rules Against Lilly in Alimta Vitamin Dosage Regimen Patent Lawsuit 115 May 14, 2014: Clovis Oncology Announces Clinical Data Of Lucitanib to Be Presented at 2014 ASCO Annual Meeting 116 Jan 16, 2014: Biothera Research Shows Potential for Treating Imprime PGG Biomarker-Negative Cancer Patients 116 Aug 13, 2013: Eli Lilly and Company's Phase III study of necitumumab meets primary endpoint 117 Jun 04, 2013: Debiopharm Announces Additional Phase I Clinical Trial Evaluating Debio 1143 Combined With Chemotherapies For Patients With Selected Solid Malignancies 118 May 23, 2013: OncoGenex Pharma Announces Plans For Initiation Of Cedar Clinical Trial Evaluating OGX-427 In Combination With Chemotherapy In Advanced Squamous Cell Lung Cancer 118 May 15, 2013: Boehringer Ingelheim To Present Six Abstracts For Nintedanib At ASCO 2013 119 Apr 08, 2013: Ariad Pharma Presents New Preclinical Data On Ponatinib At AACR Annual Meeting 2013 120 Mar 28, 2013: Oncolytics Biotech Meets Primary Overall Statistical Endpoint In US Phase II Study Of Reolysin In Squamous Cell Lung Cancer 121 Appendix 122 Methodology 122 Coverage 122 Secondary Research 122 Primary Research 122 Expert Panel Validation 122 Contact Us 123 Disclaimer 123
List of Tables Number of Products under Development for Squamous Non-Small Cell Lung Cancer, H2 2014 9 Number of Products under Development for Squamous Non-Small Cell Lung Cancer - Comparative Analysis, H2 2014 10 Number of Products under Development by Companies, H2 2014 12 Comparative Analysis by Late Stage Development, H2 2014 13 Comparative Analysis by Clinical Stage Development, H2 2014 14 Products under Development by Companies, H2 2014 15 Squamous Non-Small Cell Lung Cancer - Pipeline by Bristol-Myers Squibb Company, H2 2014 16 Squamous Non-Small Cell Lung Cancer - Pipeline by Johnson & Johnson, H2 2014 17 Squamous Non-Small Cell Lung Cancer - Pipeline by Boehringer Ingelheim GmbH, H2 2014 18 Squamous Non-Small Cell Lung Cancer - Pipeline by AstraZeneca PLC, H2 2014 19 Squamous Non-Small Cell Lung Cancer - Pipeline by Eli Lilly and Company, H2 2014 20 Squamous Non-Small Cell Lung Cancer - Pipeline by Novartis AG, H2 2014 21 Squamous Non-Small Cell Lung Cancer - Pipeline by Eisai Co., Ltd., H2 2014 22 Squamous Non-Small Cell Lung Cancer - Pipeline by Ono Pharmaceutical Co., Ltd., H2 2014 23 Squamous Non-Small Cell Lung Cancer - Pipeline by Vertex Pharmaceuticals Incorporated, H2 2014 24 Squamous Non-Small Cell Lung Cancer - Pipeline by Celgene Corporation, H2 2014 25 Squamous Non-Small Cell Lung Cancer - Pipeline by Bayer AG, H2 2014 26 Squamous Non-Small Cell Lung Cancer - Pipeline by Oncogenex Pharmaceuticals, Inc., H2 2014 27 Squamous Non-Small Cell Lung Cancer - Pipeline by Ascenta Therapeutics, Inc., H2 2014 28 Squamous Non-Small Cell Lung Cancer - Pipeline by Five Prime Therapeutics, Inc., H2 2014 29 Squamous Non-Small Cell Lung Cancer - Pipeline by Advenchen Laboratories, LLC, H2 2014 30 Squamous Non-Small Cell Lung Cancer - Pipeline by AbbVie Inc., H2 2014 31 Assessment by Monotherapy Products, H2 2014 32 Number of Products by Stage and Target, H2 2014 35 Number of Products by Stage and Mechanism of Action, H2 2014 38 Number of Products by Stage and Route of Administration, H2 2014 40 Number of Products by Stage and Molecule Type, H2 2014 42 Squamous Non-Small Cell Lung Cancer Therapeutics - Recent Pipeline Updates, H2 2014 82 Squamous Non-Small Cell Lung Cancer - Dormant Projects, H2 2014 113 Squamous Non-Small Cell Lung Cancer - Discontinued Products, H2 2014 114
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