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Published: Oct, 2014 | Pages:
74 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Spasticity - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Spasticity - Pipeline Review, H2 2014', provides an overview of the Spasticity's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Spasticity, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Spasticity and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Spasticity - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Spasticity and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Spasticity products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Spasticity pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Spasticity - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Spasticity pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Spasticity Overview 7 Therapeutics Development 8 Pipeline Products for Spasticity - Overview 8 Pipeline Products for Spasticity - Comparative Analysis 9 Spasticity - Therapeutics under Development by Companies 10 Spasticity - Pipeline Products Glance 12 Late Stage Products 12 Clinical Stage Products 13 Early Stage Products 14 Spasticity - Products under Development by Companies 15 Spasticity - Companies Involved in Therapeutics Development 16 Addex Therapeutics Ltd 16 Canbex Therapeutics Ltd. 17 Concert Pharmaceuticals, Inc. 18 Echo Pharmaceuticals B.V. 19 Escape Therapeutics, Inc. 20 GW Pharmaceuticals plc 21 Merz Pharma GmbH & Co. KgaA 22 Novartis AG 23 Osmotica Pharmaceutical Corp. 24 Raptor Pharmaceuticals Corp. 25 SciFluor Life Sciences, LLC 26 Spasticity - Therapeutics Assessment 27 Assessment by Monotherapy Products 27 Assessment by Target 28 Assessment by Mechanism of Action 30 Assessment by Route of Administration 32 Assessment by Molecule Type 34 Drug Profiles 36 ADX-71441 - Drug Profile 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 arbaclofen ER - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 CTP-354 - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 dronabinol - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 incobotulinumtoxin A - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 nabiximols - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 NGX-426 - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 onabotulinumtoxin A - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 selurampanel - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Small Molecule for Spasticity - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 tezampanel - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 VSN-16R - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 Spasticity - Recent Pipeline Updates 54 Spasticity - Dormant Projects 63 Spasticity - Discontinued Products 64 Spasticity - Product Development Milestones 65 Featured News & Press Releases 65 Oct 13, 2014: Concert Pharmaceuticals Presents Positive Data from Multiple Dose Phase 1 Clinical Trial of CTP-354, Lead Candidate for the Treatment of Spasticity 65 Jul 16, 2014: Concert Pharmaceuticals Announces FDA Lifts Partial Clinical Hold for CTP-354, A Novel Drug Candidate for Spasticity 66 Oct 02, 2013: GW Pharmaceuticals Announces New Sativex Data at ECTRIMS 66 Aug 14, 2013: GW Pharmaceuticals Opens an Investigational New Drug Application in the United States for a Sativex Phase 3 Clinical Program as a Treatment for Spasticity Due to Multiple Sclerosis 68 Jul 11, 2013: Echo Pharmaceuticals Announces Phase 2 Results for Namisol, Its' Pipeline Product for Oral Administration of ?9-Tetrahydrocannabinol and Appoints The Sage Group 68 Jun 10, 2013: Concert Pharma Initiates Phase I Clinical Trial Of CTP-354 For Treatment Of Spasticity And Pain 69 May 07, 2013: GW Pharma Announces Sativex Commercialization Approval In Italy 70 Apr 10, 2013: GW Pharma's Sativex Moved To Schedule 4 Of UK Drugs Act 70 Mar 19, 2013: GW Pharma Provides Update On Pricing Negotiations For Sativex In Germany 71 Dec 10, 2012: Osmotica Pharma Initiates Phase III Studies With Arbaclofen ER Tablets 72 Appendix 73 Methodology 73 Coverage 73 Secondary Research 73 Primary Research 73 Expert Panel Validation 73 Contact Us 74 Disclaimer 74
List of Tables Number of Products under Development for Spasticity, H2 2014 8 Number of Products under Development for Spasticity - Comparative Analysis, H2 2014 9 Number of Products under Development by Companies, H2 2014 11 Comparative Analysis by Late Stage Development, H2 2014 12 Comparative Analysis by Clinical Stage Development, H2 2014 13 Comparative Analysis by Early Stage Development, H2 2014 14 Products under Development by Companies, H2 2014 15 Spasticity - Pipeline by Addex Therapeutics Ltd, H2 2014 16 Spasticity - Pipeline by Canbex Therapeutics Ltd., H2 2014 17 Spasticity - Pipeline by Concert Pharmaceuticals, Inc., H2 2014 18 Spasticity - Pipeline by Echo Pharmaceuticals B.V., H2 2014 19 Spasticity - Pipeline by Escape Therapeutics, Inc., H2 2014 20 Spasticity - Pipeline by GW Pharmaceuticals plc, H2 2014 21 Spasticity - Pipeline by Merz Pharma GmbH & Co. KgaA, H2 2014 22 Spasticity - Pipeline by Novartis AG, H2 2014 23 Spasticity - Pipeline by Osmotica Pharmaceutical Corp., H2 2014 24 Spasticity - Pipeline by Raptor Pharmaceuticals Corp., H2 2014 25 Spasticity - Pipeline by SciFluor Life Sciences, LLC, H2 2014 26 Assessment by Monotherapy Products, H2 2014 27 Number of Products by Stage and Target, H2 2014 29 Number of Products by Stage and Mechanism of Action, H2 2014 31 Number of Products by Stage and Route of Administration, H2 2014 33 Number of Products by Stage and Molecule Type, H2 2014 35 Spasticity Therapeutics - Recent Pipeline Updates, H2 2014 54 Spasticity - Dormant Projects, H2 2014 63 Spasticity - Discontinued Products, H2 2014 64
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