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Published: May, 2015 | Pages:
386 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Soft Tissue Sarcoma - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Soft Tissue Sarcoma - Pipeline Review, H1 2015', provides an overview of the Soft Tissue Sarcoma's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Soft Tissue Sarcoma, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Soft Tissue Sarcoma and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Soft Tissue Sarcoma - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Soft Tissue Sarcoma and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Soft Tissue Sarcoma products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Soft Tissue Sarcoma pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Soft Tissue Sarcoma - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Soft Tissue Sarcoma pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents
Table of Contents 2 List of Tables 5 List of Figures 8 Introduction 9 Global Markets Direct Report Coverage 9 Soft Tissue Sarcoma Overview 10 Therapeutics Development 11 Pipeline Products for Soft Tissue Sarcoma - Overview 11 Pipeline Products for Soft Tissue Sarcoma - Comparative Analysis 12 Soft Tissue Sarcoma - Therapeutics under Development by Companies 13 Soft Tissue Sarcoma - Therapeutics under Investigation by Universities/Institutes 18 Soft Tissue Sarcoma - Pipeline Products Glance 20 Late Stage Products 20 Clinical Stage Products 21 Early Stage Products 22 Soft Tissue Sarcoma - Products under Development by Companies 23 Soft Tissue Sarcoma - Products under Investigation by Universities/Institutes 28 Soft Tissue Sarcoma - Companies Involved in Therapeutics Development 29 A. Menarini Industrie Farmaceutiche Riunite Srl 29 Advanced Proteome Therapeutics Corporation 30 Advenchen Laboratories, LLC 31 Altor BioScience Corporation 32 Amgen Inc. 33 Bayer AG 34 Bellicum Pharmaceuticals, Inc. 35 Boehringer Ingelheim GmbH 36 CASI Pharmaceuticals Inc. 37 Celgene Corporation 38 Cellectar Biosciences, Inc. 39 CytRx Corporation 40 Daiichi Sankyo Company, Limited 41 Eisai Co., Ltd. 42 Eli Lilly and Company 43 EpiZyme, Inc. 44 Exelixis, Inc. 45 Gem Pharmaceuticals, LLC 46 Immune Design Corp. 47 Karyopharm Therapeutics, Inc. 48 Loxo Oncology, Inc. 49 MedImmune, LLC 50 Merck & Co., Inc. 51 Merrimack Pharmaceuticals, Inc. 52 Mirati Therapeutics Inc. 53 MolMed S.p.A. 54 Morphotek, Inc. 55 Nanobiotix 56 Neotropix, Inc. 57 Novartis AG 58 Oncos Therapeutics Ltd. 59 Onxeo SA 60 Pfizer Inc. 61 Pharma Mar, S.A. 62 Plexxikon Inc. 63 Polaris Pharmaceuticals, Inc. 64 Recombio S.L 65 Rigontec GmbH 66 Sanofi 67 Shionogi & Co., Ltd. 68 Siena Biotech S.p.A. 69 Sigma-Tau S.p.A. 70 Sumitomo Dainippon Pharma Co., Ltd. 71 Threshold Pharmaceuticals, Inc. 72 TRACON Pharmaceuticals, Inc. 73 Vicore Pharma AB 74 Soft Tissue Sarcoma - Therapeutics Assessment 75 Assessment by Monotherapy Products 75 Assessment by Combination Products 76 Assessment by Target 77 Assessment by Mechanism of Action 82 Assessment by Route of Administration 86 Assessment by Molecule Type 88 Drug Profiles 90 afatinib - Drug Profile 90 AL-3818 - Drug Profile 94 aldoxorubicin hydrochloride - Drug Profile 96 ALT-836 - Drug Profile 99 APC-103 - Drug Profile 101 belinostat - Drug Profile 102 BI-853520 - Drug Profile 105 C-21 - Drug Profile 106 cabazitaxel - Drug Profile 108 cabozantinib s-malate - Drug Profile 110 cancer vaccine - Drug Profile 113 Cell Therapy 2 for Oncology and Infectious Disease - Drug Profile 114 Cell Therapy for GD2 Expressing Solid Tumors - Drug Profile 115 Cell Therapy to Target LMP-1 and LMP-2 for Oncology - Drug Profile 116 Cell Therapy to Target LMP-1 and LMP-2 for Oncology and Infectious Diseases - Drug Profile 117 celyvir - Drug Profile 118 Dendritic Cell Therapy to Target MAGE-A1, MAGE-A3 and NY-ESO-1 for Oncology - Drug Profile 120 Dendritic Cells + Cytokine Induced Killer Cells - Drug Profile 121 DSR-6434 - Drug Profile 122 durvalumab + tremelimumab - Drug Profile 123 E-6438 - Drug Profile 125 efatutazone - Drug Profile 127 ENMD-2076 - Drug Profile 129 eribulin mesylate - Drug Profile 131 everolimus - Drug Profile 135 evofosfamide - Drug Profile 140 G-100 - Drug Profile 148 ganitumab - Drug Profile 149 GPX-150 - Drug Profile 152 I131-CLR1404 - Drug Profile 155 ImOl-100 - Drug Profile 157 irinotecan sucrosofate liposomal - Drug Profile 158 KRA-0008 - Drug Profile 161 LK-3 - Drug Profile 162 LOXO-101 - Drug Profile 163 mocetinostat - Drug Profile 165 MVXONCO-1 - Drug Profile 168 NBTX-TOPO - Drug Profile 169 NBTXR-3 - Drug Profile 170 NGR-hTNF - Drug Profile 172 NOV-110501 - Drug Profile 176 NTX-010 - Drug Profile 177 olaratumab - Drug Profile 179 ONCOS-102 - Drug Profile 181 ontuxizumab - Drug Profile 182 paclitaxel albumin bound - Drug Profile 184 palbociclib - Drug Profile 187 panobinostat - Drug Profile 191 pazopanib hydrochloride - Drug Profile 197 pembrolizumab - Drug Profile 202 Peptide to Target COX-2 and MAS-GPCR for Oncology - Drug Profile 209 PLX-7486 - Drug Profile 211 regorafenib - Drug Profile 212 ribociclib - Drug Profile 215 S-588410 - Drug Profile 218 sabarubicin - Drug Profile 219 selinexor - Drug Profile 221 SEN-461 - Drug Profile 226 SST-0001 - Drug Profile 227 talimogene laherparepvec - Drug Profile 228 TNF-PEG 20 - Drug Profile 231 trabectedin - Drug Profile 232 TRC-105 - Drug Profile 236 vorinostat - Drug Profile 239 Soft Tissue Sarcoma - Recent Pipeline Updates 243 Soft Tissue Sarcoma - Dormant Projects 366 Soft Tissue Sarcoma - Discontinued Products 371 Soft Tissue Sarcoma - Product Development Milestones 372 Featured News & Press Releases 372 Appendix 381 Methodology 381 Coverage 381 Secondary Research 381 Primary Research 381 Expert Panel Validation 381 Contact Us 381 Disclaimer 382
List of Tables
Number of Products under Development for Soft Tissue Sarcoma, H1 2015 15 Number of Products under Development for Soft Tissue Sarcoma - Comparative Analysis, H1 2015 16 Number of Products under Development by Companies, H1 2015 18 Number of Products under Development by Companies, H1 2015 (Contd..1) 19 Number of Products under Development by Companies, H1 2015 (Contd..2) 20 Number of Products under Development by Companies, H1 2015 (Contd..3) 21 Number of Products under Investigation by Universities/Institutes, H1 2015 23 Comparative Analysis by Late Stage Development, H1 2015 24 Comparative Analysis by Clinical Stage Development, H1 2015 25 Comparative Analysis by Early Stage Development, H1 2015 26 Products under Development by Companies, H1 2015 27 Products under Development by Companies, H1 2015 (Contd..1) 28 Products under Development by Companies, H1 2015 (Contd..2) 29 Products under Development by Companies, H1 2015 (Contd..3) 30 Products under Development by Companies, H1 2015 (Contd..4) 31 Products under Investigation by Universities/Institutes, H1 2015 32 Soft Tissue Sarcoma - Pipeline by A. Menarini Industrie Farmaceutiche Riunite Srl, H1 2015 33 Soft Tissue Sarcoma - Pipeline by Advanced Proteome Therapeutics Corporation, H1 2015 34 Soft Tissue Sarcoma - Pipeline by Advenchen Laboratories, LLC, H1 2015 35 Soft Tissue Sarcoma - Pipeline by Altor BioScience Corporation, H1 2015 36 Soft Tissue Sarcoma - Pipeline by Amgen Inc., H1 2015 37 Soft Tissue Sarcoma - Pipeline by Bayer AG, H1 2015 38 Soft Tissue Sarcoma - Pipeline by Bellicum Pharmaceuticals, Inc., H1 2015 39 Soft Tissue Sarcoma - Pipeline by Boehringer Ingelheim GmbH, H1 2015 40 Soft Tissue Sarcoma - Pipeline by CASI Pharmaceuticals Inc., H1 2015 41 Soft Tissue Sarcoma - Pipeline by Celgene Corporation, H1 2015 42 Soft Tissue Sarcoma - Pipeline by Cellectar Biosciences, Inc., H1 2015 43 Soft Tissue Sarcoma - Pipeline by CytRx Corporation, H1 2015 44 Soft Tissue Sarcoma - Pipeline by Daiichi Sankyo Company, Limited, H1 2015 45 Soft Tissue Sarcoma - Pipeline by Eisai Co., Ltd., H1 2015 46 Soft Tissue Sarcoma - Pipeline by Eli Lilly and Company, H1 2015 47 Soft Tissue Sarcoma - Pipeline by EpiZyme, Inc., H1 2015 48 Soft Tissue Sarcoma - Pipeline by Exelixis, Inc., H1 2015 49 Soft Tissue Sarcoma - Pipeline by Gem Pharmaceuticals, LLC, H1 2015 50 Soft Tissue Sarcoma - Pipeline by Immune Design Corp., H1 2015 51 Soft Tissue Sarcoma - Pipeline by Karyopharm Therapeutics, Inc., H1 2015 52 Soft Tissue Sarcoma - Pipeline by Loxo Oncology, Inc., H1 2015 53 Soft Tissue Sarcoma - Pipeline by MedImmune, LLC, H1 2015 54 Soft Tissue Sarcoma - Pipeline by Merck & Co., Inc., H1 2015 55 Soft Tissue Sarcoma - Pipeline by Merrimack Pharmaceuticals, Inc., H1 2015 56 Soft Tissue Sarcoma - Pipeline by Mirati Therapeutics Inc., H1 2015 57 Soft Tissue Sarcoma - Pipeline by MolMed S.p.A., H1 2015 58 Soft Tissue Sarcoma - Pipeline by Morphotek, Inc., H1 2015 59 Soft Tissue Sarcoma - Pipeline by Nanobiotix, H1 2015 60 Soft Tissue Sarcoma - Pipeline by Neotropix, Inc., H1 2015 61 Soft Tissue Sarcoma - Pipeline by Novartis AG, H1 2015 62 Soft Tissue Sarcoma - Pipeline by Oncos Therapeutics Ltd., H1 2015 63 Soft Tissue Sarcoma - Pipeline by Onxeo SA, H1 2015 64 Soft Tissue Sarcoma - Pipeline by Pfizer Inc., H1 2015 65 Soft Tissue Sarcoma - Pipeline by Pharma Mar, S.A., H1 2015 66 Soft Tissue Sarcoma - Pipeline by Plexxikon Inc., H1 2015 67 Soft Tissue Sarcoma - Pipeline by Polaris Pharmaceuticals, Inc., H1 2015 68 Soft Tissue Sarcoma - Pipeline by Recombio S.L, H1 2015 69 Soft Tissue Sarcoma - Pipeline by Rigontec GmbH, H1 2015 70 Soft Tissue Sarcoma - Pipeline by Sanofi, H1 2015 71 Soft Tissue Sarcoma - Pipeline by Shionogi & Co., Ltd., H1 2015 72 Soft Tissue Sarcoma - Pipeline by Siena Biotech S.p.A., H1 2015 73 Soft Tissue Sarcoma - Pipeline by Sigma-Tau S.p.A., H1 2015 74 Soft Tissue Sarcoma - Pipeline by Sumitomo Dainippon Pharma Co., Ltd., H1 2015 75 Soft Tissue Sarcoma - Pipeline by Threshold Pharmaceuticals, Inc., H1 2015 76 Soft Tissue Sarcoma - Pipeline by TRACON Pharmaceuticals, Inc., H1 2015 77 Soft Tissue Sarcoma - Pipeline by Vicore Pharma AB, H1 2015 78 Assessment by Monotherapy Products, H1 2015 79 Assessment by Combination Products, H1 2015 80 Number of Products by Stage and Target, H1 2015 82 Number of Products by Stage and Mechanism of Action, H1 2015 87 Number of Products by Stage and Route of Administration, H1 2015 91 Number of Products by Stage and Molecule Type, H1 2015 93 Soft Tissue Sarcoma Therapeutics - Recent Pipeline Updates, H1 2015 247 Soft Tissue Sarcoma - Dormant Projects, H1 2015 370 Soft Tissue Sarcoma - Dormant Projects (Contd..1), H1 2015 371 Soft Tissue Sarcoma - Dormant Projects (Contd..2), H1 2015 372 Soft Tissue Sarcoma - Dormant Projects (Contd..3), H1 2015 373 Soft Tissue Sarcoma - Dormant Projects (Contd..4), H1 2015 374 Soft Tissue Sarcoma - Discontinued Products, H1 2015 375
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