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Published: Jan, 2015 | Pages:
86 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Smallpox - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Smallpox - Pipeline Review, H1 2015', provides an overview of the Smallpox's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Smallpox, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Smallpox and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Smallpox - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Smallpox and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Smallpox products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Smallpox pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons To Buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Smallpox - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Smallpox pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Smallpox Overview 8 Therapeutics Development 9 Pipeline Products for Smallpox - Overview 9 Pipeline Products for Smallpox - Comparative Analysis 10 Smallpox - Therapeutics under Development by Companies 11 Smallpox - Pipeline Products Glance 13 Late Stage Products 13 Clinical Stage Products 14 Early Stage Products 15 Unknown Stage Products 16 Smallpox - Products under Development by Companies 17 Smallpox - Companies Involved in Therapeutics Development 18 AlphaVax, Inc. 18 Bavarian Nordic A/S 19 CEL-SCI Corporation 20 Chimerix, Inc. 21 CJ CheilJedang Corp. 22 EpiVax, Inc. 23 Inovio Pharmaceuticals, Inc. 24 MacroGenics, Inc. 25 Nanotherapeutics, Inc. 26 Oncovir, Inc. 27 SIGA Technologies, Inc. 28 Symphogen A/S 29 TapImmune Inc. 30 Tonix Pharmaceuticals Holding Corp. 31 Smallpox - Therapeutics Assessment 32 Assessment by Monotherapy Products 32 Assessment by Target 33 Assessment by Mechanism of Action 35 Assessment by Route of Administration 37 Assessment by Molecule Type 39 Drug Profiles 41 brincidofovir - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 CEL-1000 - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 cidofovir - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 CJ-50300 - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 imatinib mesylate - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 Monoclonal Antibodies for Infectious Disease - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 PL-801 - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 Poly-ICLC - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 small pox vaccine - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 smallpox (multivalent) vaccine - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 smallpox vaccine - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 smallpox vaccine - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 smallpox vaccine - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 Sym-002 - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 tecovirimat - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 TPIV-300 - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 Smallpox - Recent Pipeline Updates 63 Smallpox - Dormant Projects 76 Smallpox - Discontinued Products 77 Smallpox - Product Development Milestones 78 Featured News & Press Releases 78 Jan 16, 2015: SIGA Technologies Appeals Judgment of Delaware Court of Chancery 78 Jan 07, 2015: Delaware Court of Chancery Issues Order Specifying Amount Of Lump Sum Expectation Damages Payable To PharmAthene; Total Award When Finalized, Including Pre-Judgment Interest, Attorneys' And Expert Witness Fees, Estimated To Be In Excess Of $190 Million 78 Dec 23, 2014: Chimerix Provides Recap of 2014 Events 78 Oct 04, 2014: Bavarian Nordic Announces Exercise of Contract Option by the U.S. Government for Continued Supply of IMVAMUNE Smallpox Vaccine 80 Sep 02, 2014: Chimerix and BARDA Announce Continued Partnership in the Development of Brincidofovir for Smallpox 80 Aug 26, 2014: Bavarian Nordic Receives Order from the Canadian Government to Supply IMVAMUNE Smallpox Vaccine 81 Aug 10, 2014: Delaware Court of Chancery Orders SIGA To Pay PharmAthene Lump Sum Expectation Damages 81 Jul 31, 2014: New Data on Chimerix's Brincidofovir Supports Safety and Antiviral Activity Against Multiple Life-Threatening DNA Viruses in Organ Transplant Recipients 82 Jul 08, 2014: Chimerix Announces Three Abstracts to be Presented at the 2014 World Transplant Congress 83 Apr 22, 2014: Bavarian Nordic Announces Execution of Option on Freeze-Dried IMVAMUNE 84 Appendix 85 Methodology 85 Coverage 85 Secondary Research 85 Primary Research 85 Expert Panel Validation 85 Contact Us 85 Disclaimer 85
List of Tables Number of Products under Development for Smallpox, H1 2015 9 Number of Products under Development for Smallpox - Comparative Analysis, H1 2015 10 Number of Products under Development by Companies, H1 2015 12 Comparative Analysis by Late Stage Development, H1 2015 13 Comparative Analysis by Clinical Stage Development, H1 2015 14 Comparative Analysis by Early Stage Development, H1 2015 15 Comparative Analysis by Unknown Stage Development, H1 2015 16 Products under Development by Companies, H1 2015 17 Smallpox - Pipeline by AlphaVax, Inc., H1 2015 18 Smallpox - Pipeline by Bavarian Nordic A/S, H1 2015 19 Smallpox - Pipeline by CEL-SCI Corporation, H1 2015 20 Smallpox - Pipeline by Chimerix, Inc., H1 2015 21 Smallpox - Pipeline by CJ CheilJedang Corp., H1 2015 22 Smallpox - Pipeline by EpiVax, Inc., H1 2015 23 Smallpox - Pipeline by Inovio Pharmaceuticals, Inc., H1 2015 24 Smallpox - Pipeline by MacroGenics, Inc., H1 2015 25 Smallpox - Pipeline by Nanotherapeutics, Inc., H1 2015 26 Smallpox - Pipeline by Oncovir, Inc., H1 2015 27 Smallpox - Pipeline by SIGA Technologies, Inc., H1 2015 28 Smallpox - Pipeline by Symphogen A/S, H1 2015 29 Smallpox - Pipeline by TapImmune Inc., H1 2015 30 Smallpox - Pipeline by Tonix Pharmaceuticals Holding Corp., H1 2015 31 Assessment by Monotherapy Products, H1 2015 32 Number of Products by Stage and Target, H1 2015 34 Number of Products by Stage and Mechanism of Action, H1 2015 36 Number of Products by Stage and Route of Administration, H1 2015 38 Number of Products by Stage and Molecule Type, H1 2015 40 Smallpox Therapeutics - Recent Pipeline Updates, H1 2015 63 Smallpox - Dormant Projects, H1 2015 76 Smallpox - Discontinued Products, H1 2015 77
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