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Published: Dec, 2015 | Pages:
564 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Small-Cell Lung Cancer - Pipeline Review, H2 2015 Summary Global Markets Direct's, 'Small-Cell Lung Cancer - Pipeline Review, H2 2015', provides an overview of the Small-Cell Lung Cancer's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Small-Cell Lung Cancer, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Small-Cell Lung Cancer and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Small-Cell Lung Cancer - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Small-Cell Lung Cancer and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Small-Cell Lung Cancer products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Small-Cell Lung Cancer pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Small-Cell Lung Cancer - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Small-Cell Lung Cancer pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents
Table of Contents 2 List of Tables 7 List of Figures 9 Introduction 10 Global Markets Direct Report Coverage 10 Small-Cell Lung Cancer Overview 11 Therapeutics Development 12 Pipeline Products for Small-Cell Lung Cancer - Overview 12 Pipeline Products for Small-Cell Lung Cancer - Comparative Analysis 13 Small-Cell Lung Cancer - Therapeutics under Development by Companies 14 Small-Cell Lung Cancer - Therapeutics under Investigation by Universities/Institutes 20 Small-Cell Lung Cancer - Pipeline Products Glance 21 Late Stage Products 21 Clinical Stage Products 22 Early Stage Products 23 Unknown Stage Products 24 Small-Cell Lung Cancer - Products under Development by Companies 25 Small-Cell Lung Cancer - Products under Investigation by Universities/Institutes 32 Small-Cell Lung Cancer - Companies Involved in Therapeutics Development 33 3B Pharmaceuticals GmbH 33 4SC AG 34 A. Menarini Industrie Farmaceutiche Riunite Srl 35 AbbVie Inc. 36 Alchemia Limited 37 Amgen Inc. 38 Andarix Pharmaceuticals, Inc. 39 Aposense Ltd. 40 Array BioPharma Inc. 41 Astellas Pharma Inc. 42 AstraZeneca Plc 43 AVEO Pharmaceuticals, Inc. 44 Bayer AG 45 BIND Therapeutics, Inc. 46 Blend Therapeutics, Inc. 47 Boehringer Ingelheim GmbH 48 Bristol-Myers Squibb Company 49 Cantex Pharmaceuticals, Inc. 50 Celator Pharmaceuticals, Inc. 51 CellAct Pharma GmbH 52 Cellceutix Corporation 53 Cerulean Pharma, Inc. 54 Cornerstone Pharmaceuticals, Inc. 55 Critical Outcome Technologies Inc. 56 CytRx Corporation 57 Double Bond Pharmaceutical International AB 58 Eli Lilly and Company 59 Exelixis, Inc. 60 F. Hoffmann-La Roche Ltd. 61 G1 Therapeutics, Inc. 62 Genzyme Corporation 63 GlaxoSmithKline Plc 64 Hutchison MediPharma Limited 65 Ignyta, Inc. 66 Immunomedics, Inc. 67 Inbiopro Solutions Pvt. Ltd. 68 Johnson & Johnson 69 Karyopharm Therapeutics, Inc. 70 Kolltan Pharmaceuticals, Inc. 71 Kyowa Hakko Kirin Co., Ltd. 72 Lindis Biotech GmbH 73 MabVax Therapeutics Holdings, Inc. 74 MedImmune, LLC 75 MEI Pharma, Inc. 76 Merck & Co., Inc. 77 Mersana Therapeutics, Inc. 78 Millennium Pharmaceuticals, Inc. 79 Mirna Therapeutics, Inc. 80 MolMed S.p.A. 81 Mologen AG 82 NanoSmart Pharmaceuticals, Inc. 83 Nektar Therapeutics 84 Nippon Kayaku Co., Ltd. 85 Novartis AG 86 Omnitura Therapeutics Inc. 87 OncoMed Pharmaceuticals, Inc. 88 Ono Pharmaceutical Co., Ltd. 89 Onxeo SA 90 Onyx Pharmaceuticals, Inc. 91 Oxford BioTherapeutics Ltd 92 Pfizer Inc. 93 Polaris Pharmaceuticals, Inc. 94 Rexahn Pharmaceuticals, Inc. 95 Spectrum Pharmaceuticals, Inc. 96 Sumitomo Dainippon Pharma Co., Ltd. 97 Synta Pharmaceuticals Corp. 98 Tesaro, Inc. 99 Vertex Pharmaceuticals Incorporated 100 Zensun (Shanghai) Sci & Tech Co., Ltd. 101 Small-Cell Lung Cancer - Therapeutics Assessment 102 Assessment by Monotherapy Products 102 Assessment by Combination Products 103 Assessment by Target 104 Assessment by Mechanism of Action 112 Assessment by Route of Administration 118 Assessment by Molecule Type 120 Drug Profiles 122 (irinotecan hydrochloride + cisplatin) - Drug Profile 122 3BP-227 - Drug Profile 123 4SC-202 - Drug Profile 124 ABT-737 - Drug Profile 126 Adva-27a - Drug Profile 128 aldoxorubicin hydrochloride - Drug Profile 130 alisertib - Drug Profile 133 Alocrest - Drug Profile 137 amrubicin hydrochloride - Drug Profile 139 ATT-11T - Drug Profile 141 AV-203 - Drug Profile 142 AZD-2811 - Drug Profile 143 AZD-3965 - Drug Profile 144 BAY-1112054 - Drug Profile 146 belinostat - Drug Profile 147 binimetinib - Drug Profile 150 BIW-8962 - Drug Profile 155 BMS-986012 - Drug Profile 156 BMS-986158 - Drug Profile 157 cabozantinib s-malate - Drug Profile 158 CAP-7.1 - Drug Profile 162 carboplatin - Drug Profile 164 carfilzomib - Drug Profile 165 Cellular Immunotherapy 2 for Oncology - Drug Profile 169 COTI-2 - Drug Profile 170 COTI-219 - Drug Profile 173 COTI-4 - Drug Profile 174 COTI-58 - Drug Profile 175 CPI-613 - Drug Profile 176 CRLX-101 - Drug Profile 179 CX-01 - Drug Profile 182 Cyt-PLAT - Drug Profile 184 DTP-348 - Drug Profile 185 durvalumab + tremelimumab - Drug Profile 187 erismodegib - Drug Profile 189 etirinotecan pegol - Drug Profile 192 etoposide phosphate next generation - Drug Profile 195 G-1T28 - Drug Profile 196 ganetespib - Drug Profile 198 GSK-2879552 - Drug Profile 203 GSK-525762 - Drug Profile 204 HMPL-453 - Drug Profile 205 HuMab-5B1 - Drug Profile 206 IBPM-002BZ - Drug Profile 207 ipilimumab - Drug Profile 208 irinotecan hydrochloride - Drug Profile 213 JNJ-42756493 - Drug Profile 215 KIT-SG3227 - Drug Profile 217 KM-3174 - Drug Profile 219 LY-2510924 - Drug Profile 223 ME-344 - Drug Profile 225 MGN-1703 - Drug Profile 227 MK-2206 + selumetinib sulfate - Drug Profile 231 Monoclonal Antibodies to Inhibit Vasopressin V2 Receptor for Small-Cell Lung Cancer - Drug Profile 233 MRX-34 - Drug Profile 234 MX-225 - Drug Profile 236 NGR-hTNF - Drug Profile 237 nintedanib - Drug Profile 241 niraparib - Drug Profile 246 nivolumab - Drug Profile 248 NK-012 - Drug Profile 256 olaparib - Drug Profile 258 OMN-54 - Drug Profile 262 OSI-930 - Drug Profile 264 OX-004 - Drug Profile 265 pasireotide ER - Drug Profile 266 pegargiminase - Drug Profile 268 pembrolizumab - Drug Profile 272 PEN-221 - Drug Profile 281 PF-4989216 - Drug Profile 282 Recombinant Peptide to Target EGFR for Oncology - Drug Profile 283 RG-6016 - Drug Profile 284 roniciclib - Drug Profile 286 rovalpituzumab tesirine - Drug Profile 288 RRX-001 - Drug Profile 289 RX-3117 - Drug Profile 291 SA-083 - Drug Profile 292 sabarubicin - Drug Profile 293 sacituzumab - Drug Profile 295 SC-002 - Drug Profile 297 selinexor - Drug Profile 298 Small Molecules for Small Cell Lung Cancer - Drug Profile 304 Small Molecules to Inhibit eIF-4A for Oncology - Drug Profile 305 Small Molecules to Inhibit EZH2-EED for Cancer - Drug Profile 306 solitomab - Drug Profile 307 STA-128666 - Drug Profile 308 STA-129183 - Drug Profile 310 Synthetic Peptides for Small Cell Lung Cancer and Breast Cancer - Drug Profile 311 taladegib - Drug Profile 312 tarextumab - Drug Profile 313 TF-2 - Drug Profile 315 topotecan hydrochloride - Drug Profile 317 Tozaride - Drug Profile 318 TRBS-07 - Drug Profile 320 ulocuplumab - Drug Profile 321 Vaccine for Small Cell Lung Cancer - Drug Profile 323 vandetanib - Drug Profile 325 veliparib - Drug Profile 331 vorinostat - Drug Profile 335 VX-970 - Drug Profile 339 X-396 - Drug Profile 340 XMT-1001 - Drug Profile 341 ZS-05 - Drug Profile 343 Small-Cell Lung Cancer - Recent Pipeline Updates 344 Small-Cell Lung Cancer - Dormant Projects 541 Small-Cell Lung Cancer - Discontinued Products 547 Small-Cell Lung Cancer - Product Development Milestones 548 Featured News & Press Releases 548 Appendix 555 Methodology 555 Coverage 555 Secondary Research 555 Primary Research 555 Expert Panel Validation 555 Contact Us 555 Disclaimer 556
List of Tables
Number of Products under Development for Small-Cell Lung Cancer, H2 2015 20 Number of Products under Development for Small-Cell Lung Cancer - Comparative Analysis, H2 2015 21 Number of Products under Development by Companies, H2 2015 23 Number of Products under Development by Companies, H2 2015 (Contd..1) 24 Number of Products under Development by Companies, H2 2015 (Contd..2) 25 Number of Products under Development by Companies, H2 2015 (Contd..3) 26 Number of Products under Development by Companies, H2 2015 (Contd..4) 27 Number of Products under Investigation by Universities/Institutes, H2 2015 28 Comparative Analysis by Late Stage Development, H2 2015 29 Comparative Analysis by Clinical Stage Development, H2 2015 30 Comparative Analysis by Early Stage Development, H2 2015 31 Comparative Analysis by Unknown Stage Development, H2 2015 32 Products under Development by Companies, H2 2015 33 Products under Development by Companies, H2 2015 (Contd..1) 34 Products under Development by Companies, H2 2015 (Contd..2) 35 Products under Development by Companies, H2 2015 (Contd..3) 36 Products under Development by Companies, H2 2015 (Contd..4) 37 Products under Development by Companies, H2 2015 (Contd..5) 38 Products under Development by Companies, H2 2015 (Contd..6) 39 Products under Investigation by Universities/Institutes, H2 2015 40 Small-Cell Lung Cancer - Pipeline by 3B Pharmaceuticals GmbH, H2 2015 41 Small-Cell Lung Cancer - Pipeline by 4SC AG, H2 2015 42 Small-Cell Lung Cancer - Pipeline by A. Menarini Industrie Farmaceutiche Riunite Srl, H2 2015 43 Small-Cell Lung Cancer - Pipeline by AbbVie Inc., H2 2015 44 Small-Cell Lung Cancer - Pipeline by Alchemia Limited, H2 2015 45 Small-Cell Lung Cancer - Pipeline by Amgen Inc., H2 2015 46 Small-Cell Lung Cancer - Pipeline by Andarix Pharmaceuticals, Inc., H2 2015 47 Small-Cell Lung Cancer - Pipeline by Aposense Ltd., H2 2015 48 Small-Cell Lung Cancer - Pipeline by Array BioPharma Inc., H2 2015 49 Small-Cell Lung Cancer - Pipeline by Astellas Pharma Inc., H2 2015 50 Small-Cell Lung Cancer - Pipeline by AstraZeneca Plc, H2 2015 51 Small-Cell Lung Cancer - Pipeline by AVEO Pharmaceuticals, Inc., H2 2015 52 Small-Cell Lung Cancer - Pipeline by Bayer AG, H2 2015 53 Small-Cell Lung Cancer - Pipeline by BIND Therapeutics, Inc., H2 2015 54 Small-Cell Lung Cancer - Pipeline by Blend Therapeutics, Inc., H2 2015 55 Small-Cell Lung Cancer - Pipeline by Boehringer Ingelheim GmbH, H2 2015 56 Small-Cell Lung Cancer - Pipeline by Bristol-Myers Squibb Company, H2 2015 57 Small-Cell Lung Cancer - Pipeline by Cantex Pharmaceuticals, Inc., H2 2015 58 Small-Cell Lung Cancer - Pipeline by Celator Pharmaceuticals, Inc., H2 2015 59 Small-Cell Lung Cancer - Pipeline by CellAct Pharma GmbH, H2 2015 60 Small-Cell Lung Cancer - Pipeline by Cellceutix Corporation, H2 2015 61 Small-Cell Lung Cancer - Pipeline by Cerulean Pharma, Inc., H2 2015 62 Small-Cell Lung Cancer - Pipeline by Cornerstone Pharmaceuticals, Inc., H2 2015 63 Small-Cell Lung Cancer - Pipeline by Critical Outcome Technologies Inc., H2 2015 64 Small-Cell Lung Cancer - Pipeline by CytRx Corporation, H2 2015 65 Small-Cell Lung Cancer - Pipeline by Double Bond Pharmaceutical International AB, H2 2015 66 Small-Cell Lung Cancer - Pipeline by Eli Lilly and Company, H2 2015 67 Small-Cell Lung Cancer - Pipeline by Exelixis, Inc., H2 2015 68 Small-Cell Lung Cancer - Pipeline by F. Hoffmann-La Roche Ltd., H2 2015 69 Small-Cell Lung Cancer - Pipeline by G1 Therapeutics, Inc., H2 2015 70 Small-Cell Lung Cancer - Pipeline by Genzyme Corporation, H2 2015 71 Small-Cell Lung Cancer - Pipeline by GlaxoSmithKline Plc, H2 2015 72 Small-Cell Lung Cancer - Pipeline by Hutchison MediPharma Limited, H2 2015 73 Small-Cell Lung Cancer - Pipeline by Ignyta, Inc., H2 2015 74 Small-Cell Lung Cancer - Pipeline by Immunomedics, Inc., H2 2015 75 Small-Cell Lung Cancer - Pipeline by Inbiopro Solutions Pvt. Ltd., H2 2015 76 Small-Cell Lung Cancer - Pipeline by Johnson & Johnson, H2 2015 77 Small-Cell Lung Cancer - Pipeline by Karyopharm Therapeutics, Inc., H2 2015 78 Small-Cell Lung Cancer - Pipeline by Kolltan Pharmaceuticals, Inc., H2 2015 79 Small-Cell Lung Cancer - Pipeline by Kyowa Hakko Kirin Co., Ltd., H2 2015 80 Small-Cell Lung Cancer - Pipeline by Lindis Biotech GmbH, H2 2015 81 Small-Cell Lung Cancer - Pipeline by MabVax Therapeutics Holdings, Inc., H2 2015 82 Small-Cell Lung Cancer - Pipeline by MedImmune, LLC, H2 2015 83 Small-Cell Lung Cancer - Pipeline by MEI Pharma, Inc., H2 2015 84 Small-Cell Lung Cancer - Pipeline by Merck & Co., Inc., H2 2015 85 Small-Cell Lung Cancer - Pipeline by Mersana Therapeutics, Inc., H2 2015 86 Small-Cell Lung Cancer - Pipeline by Millennium Pharmaceuticals, Inc., H2 2015 87 Small-Cell Lung Cancer - Pipeline by Mirna Therapeutics, Inc., H2 2015 88 Small-Cell Lung Cancer - Pipeline by MolMed S.p.A., H2 2015 89 Small-Cell Lung Cancer - Pipeline by Mologen AG, H2 2015 90 Small-Cell Lung Cancer - Pipeline by NanoSmart Pharmaceuticals, Inc., H2 2015 91 Small-Cell Lung Cancer - Pipeline by Nektar Therapeutics, H2 2015 92 Small-Cell Lung Cancer - Pipeline by Nippon Kayaku Co., Ltd., H2 2015 93 Small-Cell Lung Cancer - Pipeline by Novartis AG, H2 2015 94 Small-Cell Lung Cancer - Pipeline by Omnitura Therapeutics Inc., H2 2015 95 Small-Cell Lung Cancer - Pipeline by OncoMed Pharmaceuticals, Inc., H2 2015 96 Small-Cell Lung Cancer - Pipeline by Ono Pharmaceutical Co., Ltd., H2 2015 97 Small-Cell Lung Cancer - Pipeline by Onxeo SA, H2 2015 98 Small-Cell Lung Cancer - Pipeline by Onyx Pharmaceuticals, Inc., H2 2015 99 Small-Cell Lung Cancer - Pipeline by Oxford BioTherapeutics Ltd, H2 2015 100 Small-Cell Lung Cancer - Pipeline by Pfizer Inc., H2 2015 101 Small-Cell Lung Cancer - Pipeline by Polaris Pharmaceuticals, Inc., H2 2015 102 Small-Cell Lung Cancer - Pipeline by Rexahn Pharmaceuticals, Inc., H2 2015 103 Small-Cell Lung Cancer - Pipeline by Spectrum Pharmaceuticals, Inc., H2 2015 104 Small-Cell Lung Cancer - Pipeline by Sumitomo Dainippon Pharma Co., Ltd., H2 2015 105 Small-Cell Lung Cancer - Pipeline by Synta Pharmaceuticals Corp., H2 2015 106 Small-Cell Lung Cancer - Pipeline by Tesaro, Inc., H2 2015 107 Small-Cell Lung Cancer - Pipeline by Vertex Pharmaceuticals Incorporated, H2 2015 108 Small-Cell Lung Cancer - Pipeline by Zensun (Shanghai) Sci & Tech Co., Ltd., H2 2015 109 Assessment by Monotherapy Products, H2 2015 110 Assessment by Combination Products, H2 2015 111 Number of Products by Stage and Target, H2 2015 113 Number of Products by Stage and Mechanism of Action, H2 2015 121 Number of Products by Stage and Route of Administration, H2 2015 127 Number of Products by Stage and Molecule Type, H2 2015 129 Small-Cell Lung Cancer Therapeutics - Recent Pipeline Updates, H2 2015 352 Small-Cell Lung Cancer - Dormant Projects, H2 2015 549 Small-Cell Lung Cancer - Dormant Projects (Contd..1), H2 2015 550 Small-Cell Lung Cancer - Dormant Projects (Contd..2), H2 2015 551 Small-Cell Lung Cancer - Dormant Projects (Contd..3), H2 2015 552 Small-Cell Lung Cancer - Dormant Projects (Contd..4), H2 2015 553 Small-Cell Lung Cancer - Dormant Projects (Contd..5), H2 2015 554 Small-Cell Lung Cancer - Discontinued Products, H2 2015 555
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