Seizures - Pipeline Review, H1 2015

Published: Jan, 2015 | Pages: 79 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Seizures - Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Seizures - Pipeline Review, H1 2015', provides an overview of the Seizures's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Seizures, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Seizures and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Seizures
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in the therapeutics development for Seizures and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects 
- A review of the Seizures products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Seizures pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Seizures
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Seizures pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

 Table of Contents
Table of Contents 2
List of Tables 5
List of Figures 6
Introduction 7
Global Markets Direct Report Coverage 7
Seizures Overview 8
Therapeutics Development 9
Pipeline Products for Seizures - Overview 9
Pipeline Products for Seizures - Comparative Analysis 10
Seizures - Therapeutics under Development by Companies 11
Seizures - Therapeutics under Investigation by Universities/Institutes 13
Seizures - Pipeline Products Glance 14
Late Stage Products 14
Clinical Stage Products 15
Early Stage Products 16
Seizures - Products under Development by Companies 17
Seizures - Products under Investigation by Universities/Institutes 18
Seizures - Companies Involved in Therapeutics Development 19
Acorda Therapeutics, Inc. 19
Advicenne Pharma 20
Alexza Pharmaceuticals, Inc. 21
Concert Pharmaceuticals, Inc. 22
Neurelis, Inc. 23
Novartis AG 24
Pfizer Inc. 25
Sage Therapeutics 26
Ultragenyx Pharmaceutical Inc. 27
Upsher-Smith Laboratories, Inc. 28
Seizures - Therapeutics Assessment 29
Assessment by Monotherapy Products 29
Assessment by Target 30
Assessment by Mechanism of Action 32
Assessment by Route of Administration 34
Assessment by Molecule Type 36
Drug Profiles 38
ADV-6208 - Drug Profile 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
alprazolam - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
C-10068 - Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
CCG-63802 - Drug Profile 42
Product Description 42
Mechanism of Action 42
R&D Progress 42
CHEC-9 - Drug Profile 43
Product Description 43
Mechanism of Action 43
R&D Progress 43
diazepam - Drug Profile 45
Product Description 45
Mechanism of Action 45
R&D Progress 45
diazepam - Drug Profile 46
Product Description 46
Mechanism of Action 46
R&D Progress 46
diazepam - Drug Profile 47
Product Description 47
Mechanism of Action 47
R&D Progress 47
everolimus - Drug Profile 49
Product Description 49
Mechanism of Action 49
R&D Progress 49
Gene Therapy to Activate Neuropeptide Y Receptor Y2 and Y5 for Epilepsy - Drug Profile 54
Product Description 54
Mechanism of Action 54
R&D Progress 54
midazolam hydrochloride - Drug Profile 55
Product Description 55
Mechanism of Action 55
R&D Progress 55
SAGE-217 - Drug Profile 56
Product Description 56
Mechanism of Action 56
R&D Progress 56
Small Molecules to Activate TrkB Receptor for Central Nervous System, Metabolic Disorders and ENT Disorders - Drug Profile 57
Product Description 57
Mechanism of Action 57
R&D Progress 57
UX-007 - Drug Profile 59
Product Description 59
Mechanism of Action 59
R&D Progress 59
Seizures - Recent Pipeline Updates 60
Seizures - Dormant Projects 70
Seizures - Discontinued Products 71
Seizures - Product Development Milestones 72
Featured News & Press Releases 72
Sep 02, 2014: SAGE Therapeutics Presents New Preclinical Data on SAGE-217 at Eilat Conference on New Anti-Epileptic Drugs 72
Nov 01, 2013: Systematic Review Finds Intranasal Midazolam Comparable To Intravenous Or Rectal Administration Of Diazepam For Treatment Of Acute Seizure Emergencies In Pediatric Patients 72
Jun 24, 2013: Upsher-Smith Labs Announces Patient Enrollment In Open-label Safety Study Of USL261 For Rescue Treatment Of Seizure Clusters In Epilepsy 73
May 06, 2013: Alexza Pharma To Present Data On AZ-002 At Antiepileptic Drug And Device Trials Conference 74
Mar 19, 2013: Upsher-Smith Labs Presents Favorable Phase I Data For USL261 At 65th Annual Meeting Of AAN 74
Nov 26, 2012: Upsher-Smith Labs Presents Clinical Data On Midazolam At American Epilepsy Society Annual Meeting 75
Apr 26, 2012: Upsher-Smith Provides Update On Phase III Seizure Clusters Study 76
Appendix 78
Methodology 78
Coverage 78
Secondary Research 78
Primary Research 78
Expert Panel Validation 78
Contact Us 78
Disclaimer 79

List of Tables
Number of Products under Development for Seizures, H1 2015 9
Number of Products under Development for Seizures - Comparative Analysis, H1 2015 10
Number of Products under Development by Companies, H1 2015 12
Number of Products under Investigation by Universities/Institutes, H1 2015 13
Comparative Analysis by Late Stage Development, H1 2015 14
Comparative Analysis by Clinical Stage Development, H1 2015 15
Comparative Analysis by Early Stage Development, H1 2015 16
Products under Development by Companies, H1 2015 17
Products under Investigation by Universities/Institutes, H1 2015 18
Seizures - Pipeline by Acorda Therapeutics, Inc., H1 2015 19
Seizures - Pipeline by Advicenne Pharma, H1 2015 20
Seizures - Pipeline by Alexza Pharmaceuticals, Inc., H1 2015 21
Seizures - Pipeline by Concert Pharmaceuticals, Inc., H1 2015 22
Seizures - Pipeline by Neurelis, Inc., H1 2015 23
Seizures - Pipeline by Novartis AG, H1 2015 24
Seizures - Pipeline by Pfizer Inc., H1 2015 25
Seizures - Pipeline by Sage Therapeutics, H1 2015 26
Seizures - Pipeline by Ultragenyx Pharmaceutical Inc., H1 2015 27
Seizures - Pipeline by Upsher-Smith Laboratories, Inc., H1 2015 28
Assessment by Monotherapy Products, H1 2015 29
Number of Products by Stage and Target, H1 2015 31
Number of Products by Stage and Mechanism of Action, H1 2015 33
Number of Products by Stage and Route of Administration, H1 2015 35
Number of Products by Stage and Molecule Type, H1 2015 37
Seizures Therapeutics - Recent Pipeline Updates, H1 2015 60
Seizures - Dormant Projects, H1 2015 70
Seizures - Discontinued Products, H1 2015 71