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Published: Jan, 2015 | Pages:
47 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Restless Legs Syndrome - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Restless Legs Syndrome - Pipeline Review, H1 2015', provides an overview of the Restless Legs Syndrome's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Restless Legs Syndrome, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Restless Legs Syndrome and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Restless Legs Syndrome - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Restless Legs Syndrome and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Restless Legs Syndrome products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Restless Legs Syndrome pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Restless Legs Syndrome - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Restless Legs Syndrome pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Restless Legs Syndrome Overview 6 Therapeutics Development 7 Pipeline Products for Restless Legs Syndrome - Overview 7 Pipeline Products for Restless Legs Syndrome - Comparative Analysis 8 Restless Legs Syndrome - Therapeutics under Development by Companies 9 Restless Legs Syndrome - Pipeline Products Glance 10 Late Stage Products 10 Clinical Stage Products 11 Early Stage Products 12 Restless Legs Syndrome - Products under Development by Companies 13 Restless Legs Syndrome - Companies Involved in Therapeutics Development 14 Alexza Pharmaceuticals, Inc. 14 Ascendis Pharma A/S 15 Hisamitsu Pharmaceutical Co., Inc. 16 Ligand Pharmaceuticals, Inc. 17 Omeros Corporation 18 Purdue Pharma L.P. 19 Serina Therapeutics, Inc. 20 Restless Legs Syndrome - Therapeutics Assessment 21 Assessment by Monotherapy Products 21 Assessment by Combination Products 22 Assessment by Target 23 Assessment by Mechanism of Action 25 Assessment by Route of Administration 27 Assessment by Molecule Type 29 Drug Profiles 30 (naloxone hydrochloride + oxycodone hydrochloride) ER - Drug Profile 30 Product Description 30 Mechanism of Action 30 R&D Progress 30 ACP-006 - Drug Profile 32 Product Description 32 Mechanism of Action 32 R&D Progress 32 aplindore fumarate - Drug Profile 33 Product Description 33 Mechanism of Action 33 R&D Progress 33 AZ-008 - Drug Profile 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 OMS-527 - Drug Profile 35 Product Description 35 Mechanism of Action 35 R&D Progress 35 ropinirole hydrochloride - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 SER-214 - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 Restless Legs Syndrome - Recent Pipeline Updates 39 Restless Legs Syndrome - Dormant Projects 41 Restless Legs Syndrome - Discontinued Products 42 Restless Legs Syndrome - Product Development Milestones 43 Featured News & Press Releases 43 Oct 24, 2014: Mundipharma receives Positive CHMP Opinion for Targin (oxycodone / naloxone) for the treatment of Restless Legs Syndrome 43 Jan 07, 2014: Mundipharma receives positive European Commission decision on Targin (oxycodone/naloxone) for the treatment of Restless Legs Syndrome 43 Nov 19, 2013: New data show efficacy of prolonged release TARGIN (oxycodone / naloxone) in the treatment of severe restless legs syndrome 44 Oct 16, 2008: Neurogen Announces Positive Top-Line Results From Two Phase II Trials For Aplindore In Restless Legs Syndrome And Parkinson's Disease 45 Appendix 46 Methodology 46 Coverage 46 Secondary Research 46 Primary Research 46 Expert Panel Validation 46 Contact Us 46 Disclaimer 47
List of Tables Number of Products under Development for Restless Legs Syndrome, H1 2015 7 Number of Products under Development for Restless Legs Syndrome - Comparative Analysis, H1 2015 8 Number of Products under Development by Companies, H1 2015 9 Comparative Analysis by Late Stage Development, H1 2015 10 Comparative Analysis by Clinical Stage Development, H1 2015 11 Comparative Analysis by Early Stage Development, H1 2015 12 Products under Development by Companies, H1 2015 13 Restless Legs Syndrome - Pipeline by Alexza Pharmaceuticals, Inc., H1 2015 14 Restless Legs Syndrome - Pipeline by Ascendis Pharma A/S, H1 2015 15 Restless Legs Syndrome - Pipeline by Hisamitsu Pharmaceutical Co., Inc., H1 2015 16 Restless Legs Syndrome - Pipeline by Ligand Pharmaceuticals, Inc., H1 2015 17 Restless Legs Syndrome - Pipeline by Omeros Corporation, H1 2015 18 Restless Legs Syndrome - Pipeline by Purdue Pharma L.P., H1 2015 19 Restless Legs Syndrome - Pipeline by Serina Therapeutics, Inc., H1 2015 20 Assessment by Monotherapy Products, H1 2015 21 Assessment by Combination Products, H1 2015 22 Number of Products by Stage and Target, H1 2015 24 Number of Products by Stage and Mechanism of Action, H1 2015 26 Number of Products by Stage and Route of Administration, H1 2015 28 Number of Products by Stage and Molecule Type, H1 2015 29 Restless Legs Syndrome Therapeutics - Recent Pipeline Updates, H1 2015 39 Restless Legs Syndrome - Dormant Projects, H1 2015 41 Restless Legs Syndrome - Discontinued Products, H1 2015 42
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