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Published: Aug, 2014 | Pages:
80 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline Review, H2 2014', provides an overview of the Reflux Esophagitis (Gastroesophageal Reflux Disease)'s therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Reflux Esophagitis (Gastroesophageal Reflux Disease), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Reflux Esophagitis (Gastroesophageal Reflux Disease) and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Reflux Esophagitis (Gastroesophageal Reflux Disease) - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Reflux Esophagitis (Gastroesophageal Reflux Disease) and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Reflux Esophagitis (Gastroesophageal Reflux Disease) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Reflux Esophagitis (Gastroesophageal Reflux Disease) pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Reflux Esophagitis (Gastroesophageal Reflux Disease) - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Reflux Esophagitis (Gastroesophageal Reflux Disease) pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Reflux Esophagitis (Gastroesophageal Reflux Disease) Overview 8 Therapeutics Development 9 Pipeline Products for Reflux Esophagitis (Gastroesophageal Reflux Disease) - Overview 9 Pipeline Products for Reflux Esophagitis (Gastroesophageal Reflux Disease) - Comparative Analysis 10 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Therapeutics under Development by Companies 11 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Therapeutics under Investigation by Universities/Institutes 13 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline Products Glance 14 Late Stage Products 14 Clinical Stage Products 15 Early Stage Products 16 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Products under Development by Companies 17 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Products under Investigation by Universities/Institutes 18 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Companies Involved in Therapeutics Development 19 Johnson & Johnson 19 Takeda Pharmaceutical Company Limited 20 Eisai Co., Ltd. 21 Ono Pharmaceutical Co., Ltd. 22 Wockhardt Limited 23 Shire Plc 24 Yuhan Corporation 25 Torrent Pharmaceuticals Limited 26 Ahn-Gook Pharmaceutical Co., Ltd. 27 Ironwood Pharmaceuticals, Inc. 28 Rottapharm SpA 29 aRigen Pharmaceuticals, Inc. 30 Cempra, Inc. 31 Vecta Ltd. 32 RaQualia Pharma Inc. 33 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Therapeutics Assessment 34 Assessment by Monotherapy Products 34 Assessment by Combination Products 35 Assessment by Target 36 Assessment by Mechanism of Action 38 Assessment by Route of Administration 40 Assessment by Molecule Type 42 Drug Profiles 44 vonoprazan - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 pantoprazole - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 (esomeprazole magnesium + levosulpiride) - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 omeprazole - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 itriglumide - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 RQ-00000004 - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 SSP-002358 - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 YH-4808 - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 Polyclonal Antibody Stimulator - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 IW-3718 - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 esomeprazole magnesium - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 tenatoprazole - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 E-3710 - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 ARH-1029 - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 RQ-00000010 - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 ONO-8539 - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 RQ-00000774 - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 Small Molecules to Agonize Motilin Receptor for GERD and Diabetic Gastroparesis - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 JNJ-26070109 - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 Small Molecules to Inhibit Proton Pump for Gastrointestinal Disorders - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Recent Pipeline Updates 67 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Dormant Projects 71 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Discontinued Products 72 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Product Development Milestones 73 Featured News & Press Releases 73 Mar 18, 2014: Ironwood Pharmaceuticals Initiates Phase II Clinical Study of IW-3718 in Refractory Gastroesophageal Reflux Disease 73 Dec 23, 2013: Federal Appeals Court Ruling Affirms Amneal's Green Light to Market New Esomeprazole Strontium Delayed-Release Capsules 73 Dec 19, 2013: Dexlansoprazole, a New Dual-Delayed Release Technology for the Treatment Of Reflux Disease, Accepted for National Approvals Within the European Union 74 Dec 17, 2013: Amneal Launches Esomeprazole Strontium 49.3 mg Delayed-Release Capsules, a Pharmaceutical Alternative to Nexium 75 Dec 17, 2013: AstraZeneca statement in response to reports of a launch of esomeprazole strontium product in the US 75 Nov 08, 2013: Eisai Announces Availability of ACIPHEX Sprinkle for Treatment of GERD in Children Ages 1 to 11 75 Oct 15, 2013: TWi Pharmaceuticals Comments on Dexilant Ruling 76 Mar 27, 2013: Eisai's Aciphex Sprinkle Capsules Obtains FDA Approval For Treatment Of Gastroesophageal Reflux Disease In Children 77 Mar 25, 2013: Takeda Receives Decision From President Of National Tax Tribunal Related To Correction Notice On Transfer Pricing Of Prevacid 77 Dec 10, 2012: Eisai Receives Six-month Pediatric Exclusivity For Proton-pump Inhibitor Aciphex In US 77 Appendix 79 Methodology 79 Coverage 79 Secondary Research 79 Primary Research 79 Expert Panel Validation 79 Contact Us 80 Disclaimer 80
List of Tables Number of Products under Development for Reflux Esophagitis (Gastroesophageal Reflux Disease), H2 2014 9 Number of Products under Development for Reflux Esophagitis (Gastroesophageal Reflux Disease) - Comparative Analysis, H2 2014 10 Number of Products under Development by Companies, H2 2014 12 Number of Products under Investigation by Universities/Institutes, H2 2014 13 Comparative Analysis by Late Stage Development, H2 2014 14 Comparative Analysis by Clinical Stage Development, H2 2014 15 Comparative Analysis by Early Stage Development, H2 2014 16 Products under Development by Companies, H2 2014 17 Products under Investigation by Universities/Institutes, H2 2014 18 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Johnson & Johnson, H2 2014 19 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Takeda Pharmaceutical Company Limited, H2 2014 20 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Eisai Co., Ltd., H2 2014 21 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Ono Pharmaceutical Co., Ltd., H2 2014 22 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Wockhardt Limited, H2 2014 23 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Shire Plc, H2 2014 24 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Yuhan Corporation, H2 2014 25 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Torrent Pharmaceuticals Limited, H2 2014 26 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Ahn-Gook Pharmaceutical Co., Ltd., H2 2014 27 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Ironwood Pharmaceuticals, Inc., H2 2014 28 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Rottapharm SpA, H2 2014 29 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by aRigen Pharmaceuticals, Inc., H2 2014 30 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Cempra, Inc., H2 2014 31 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by Vecta Ltd., H2 2014 32 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Pipeline by RaQualia Pharma Inc., H2 2014 33 Assessment by Monotherapy Products, H2 2014 34 Assessment by Combination Products, H2 2014 35 Number of Products by Stage and Target, H2 2014 37 Number of Products by Stage and Mechanism of Action, H2 2014 39 Number of Products by Stage and Route of Administration, H2 2014 41 Number of Products by Stage and Molecule Type, H2 2014 43 Reflux Esophagitis (Gastroesophageal Reflux Disease) Therapeutics - Recent Pipeline Updates, H2 2014 67 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Dormant Projects, H2 2014 71 Reflux Esophagitis (Gastroesophageal Reflux Disease) - Discontinued Products, H2 2014 72
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