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Published: Sep, 2014 | Pages:
63 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Pulmonary Tuberculosis - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Pulmonary Tuberculosis - Pipeline Review, H2 2014', provides an overview of the Pulmonary Tuberculosis's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Pulmonary Tuberculosis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Pulmonary Tuberculosis and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Pulmonary Tuberculosis - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Pulmonary Tuberculosis and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Pulmonary Tuberculosis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Pulmonary Tuberculosis pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Pulmonary Tuberculosis - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Pulmonary Tuberculosis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Pulmonary Tuberculosis Overview 7 Therapeutics Development 8 Pipeline Products for Pulmonary Tuberculosis - Overview 8 Pipeline Products for Pulmonary Tuberculosis - Comparative Analysis 9 Pulmonary Tuberculosis - Therapeutics under Development by Companies 10 Pulmonary Tuberculosis - Therapeutics under Investigation by Universities/Institutes 11 Pulmonary Tuberculosis - Pipeline Products Glance 12 Late Stage Products 12 Clinical Stage Products 13 Early Stage Products 14 Pulmonary Tuberculosis - Products under Development by Companies 15 Pulmonary Tuberculosis - Products under Investigation by Universities/Institutes 16 Pulmonary Tuberculosis - Companies Involved in Therapeutics Development 17 Johnson & Johnson 17 Sequella, Inc. 18 AstraZeneca PLC 19 Microbion Corporation 20 Pulmonary Tuberculosis - Therapeutics Assessment 21 Assessment by Monotherapy Products 21 Assessment by Combination Products 22 Assessment by Target 23 Assessment by Mechanism of Action 25 Assessment by Route of Administration 27 Assessment by Molecule Type 29 Drug Profiles 31 bedaquiline fumarate - Drug Profile 31 Product Description 31 Mechanism of Action 31 R&D Progress 31 SQ-109 - Drug Profile 33 Product Description 33 Mechanism of Action 33 R&D Progress 33 SQ-109 - Drug Profile 35 Product Description 35 Mechanism of Action 35 R&D Progress 35 sutezolid - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 posizolid - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 pretomanid - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 pulmonary tuberculosis + leprosy vaccine - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 SQ-609 - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 r30 - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 methionine sulfoximine - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 Small Molecule for Pneumonia, COPD, Cystic Fibrosis and Pulmonary Tuberculosis - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 Pulmonary Tuberculosis - Recent Pipeline Updates 51 Pulmonary Tuberculosis - Dormant Projects 56 Pulmonary Tuberculosis - Product Development Milestones 57 Featured News & Press Releases 57 Dec 20, 2013: SIRTURO Receives Positive Opinion from the Committee for MedicinalProducts for Human Use as Part of Combination Therapy to Treat Adults with Pulmonary Multi-Drug Resistant Tuberculosis 57 Jul 26, 2013: Otsuka Receives Opinion from CHMP on Delamanid 57 Jul 02, 2012: Janssen Submits New Drug Application To FDA For Bedaquiline For Multi-Drug Resistant Tuberculosis Treatment 58 Oct 18, 2010: Sequella Receives International Support For Phase II Clinical Trials Of SQ109 For Treatment Of Adult Pulmonary Tuberculosis 59 Oct 18, 2005: The Global Alliance for TB Drug Development Announces Phase II Trials To Study Potential Of Moxifloxacin To Shorten TB Treatment Partners Commit To Affordable Pricing For Patients In The Developing World 60 Appendix 62 Methodology 62 Coverage 62 Secondary Research 62 Primary Research 62 Expert Panel Validation 62 Contact Us 63 Disclaimer 63
List of Tables Number of Products under Development for Pulmonary Tuberculosis, H2 2014 8 Number of Products under Development for Pulmonary Tuberculosis - Comparative Analysis, H2 2014 9 Number of Products under Development by Companies, H2 2014 10 Number of Products under Investigation by Universities/Institutes, H2 2014 11 Comparative Analysis by Late Stage Development, H2 2014 12 Comparative Analysis by Clinical Stage Development, H2 2014 13 Comparative Analysis by Early Stage Development, H2 2014 14 Products under Development by Companies, H2 2014 15 Products under Investigation by Universities/Institutes, H2 2014 16 Pulmonary Tuberculosis - Pipeline by Johnson & Johnson, H2 2014 17 Pulmonary Tuberculosis - Pipeline by Sequella, Inc., H2 2014 18 Pulmonary Tuberculosis - Pipeline by AstraZeneca PLC, H2 2014 19 Pulmonary Tuberculosis - Pipeline by Microbion Corporation, H2 2014 20 Assessment by Monotherapy Products, H2 2014 21 Assessment by Combination Products, H2 2014 22 Number of Products by Stage and Target, H2 2014 24 Number of Products by Stage and Mechanism of Action, H2 2014 26 Number of Products by Stage and Route of Administration, H2 2014 28 Number of Products by Stage and Molecule Type, H2 2014 30 Pulmonary Tuberculosis Therapeutics - Recent Pipeline Updates, H2 2014 51 Pulmonary Tuberculosis - Dormant Projects, H2 2014 56
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