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Published: Jan, 2015 | Pages:
226 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Pulmonary Hypertension - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Pulmonary Hypertension - Pipeline Review, H1 2015', provides an overview of the Pulmonary Hypertension's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Pulmonary Hypertension, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Pulmonary Hypertension and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Pulmonary Hypertension - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Pulmonary Hypertension and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Pulmonary Hypertension products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Pulmonary Hypertension pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Pulmonary Hypertension - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Pulmonary Hypertension pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Pulmonary Hypertension Overview 9 Therapeutics Development 10 Pipeline Products for Pulmonary Hypertension - Overview 10 Pipeline Products for Pulmonary Hypertension - Comparative Analysis 11 Pulmonary Hypertension - Therapeutics under Development by Companies 12 Pulmonary Hypertension - Therapeutics under Investigation by Universities/Institutes 17 Pulmonary Hypertension - Pipeline Products Glance 18 Late Stage Products 18 Clinical Stage Products 19 Early Stage Products 20 Pulmonary Hypertension - Products under Development by Companies 21 Pulmonary Hypertension - Products under Investigation by Universities/Institutes 26 Pulmonary Hypertension - Companies Involved in Therapeutics Development 27 Actelion Ltd 27 APT Therapeutics, Inc. 28 Arena Pharmaceuticals, Inc. 29 Asahi Kasei Pharma Corp. 30 Ascendis Pharma A/S 31 Bayer AG 32 Bial - Portela & Ca, S.A. 33 Biolab Sanus Farmaceutica Ltda. 34 Cardioxyl Pharmaceuticals, Inc. 35 Carolus Therapeutics, Inc. 36 Celladon Corporation 37 Celsion Corporation 38 Corridor Pharmaceuticals Inc. 39 Cytokinetics, Inc. 40 Eli Lilly and Company 41 Gilead Sciences, Inc. 42 HanAll Biopharma Co., Ltd. 43 Hanmi Pharmaceuticals, Co. Ltd. 44 Ikaria Inc. 45 Insmed Incorporated 46 Ironwood Pharmaceuticals, Inc. 47 Lacer, S.A. 48 Longevity Biotech, Inc 49 LTT Bio-Pharma Co., Ltd. 50 Mast Therapeutics, Inc. 51 Mezzion Pharma Co. Ltd. 52 miRagen Therapeutics, Inc. 53 Nippon Shinyaku Co., Ltd. 54 Novartis AG 55 PharmaIN Corporation 56 PhaseBio Pharmaceuticals, Inc. 57 Pluristem Therapeutics Inc. 58 Proteo, Inc. 59 Reata Pharmaceuticals, Inc. 60 RegeneRx Biopharmaceuticals, Inc. 61 Sagene Pharmaceuticals, Inc. 62 Silence Therapeutics plc 63 Sinoxa Pharma GmbH 64 Suda Ltd 65 Therametrics holding AG 66 Toray Industries, Inc. 67 United Therapeutics Corporation 68 Vectura Group plc 69 Vicore Pharma AB 70 Pulmonary Hypertension - Therapeutics Assessment 71 Assessment by Monotherapy Products 71 Assessment by Combination Products 72 Assessment by Target 73 Assessment by Mechanism of Action 77 Assessment by Route of Administration 80 Assessment by Molecule Type 82 Drug Profiles 84 (allopurinol + apocynin) - Drug Profile 84 (chlorthalidone + valsartan) - Drug Profile 85 ACP-009 - Drug Profile 86 ambrisentan - Drug Profile 87 Antibody for Cancer and PAH - Drug Profile 89 Antibody for Pulmonary Arterial Hypertension - Drug Profile 90 APT-102 - Drug Profile 91 bardoxolone methyl - Drug Profile 93 BAY sGCact - Drug Profile 96 beraprost sodium nanoparticles SR - Drug Profile 97 beraprost sodium SR - Drug Profile 98 BIA-51058 - Drug Profile 100 BL-214 - Drug Profile 101 bosentan CR - Drug Profile 102 C-122 - Drug Profile 103 C-21 - Drug Profile 104 C-301 - Drug Profile 106 CT-2009 - Drug Profile 107 DasKloster-1000-01 - Drug Profile 108 Drug for Pulmonary Hypertension - Drug Profile 110 Drug for Pulmonary Hypertension - Drug Profile 111 Elafin - Drug Profile 112 esuberaprost sodium - Drug Profile 115 fasudil - Drug Profile 116 GS-4997 - Drug Profile 117 HGP-1207 - Drug Profile 118 IK-3001 - Drug Profile 119 imatinib mesylate - Drug Profile 120 IW-1973 - Drug Profile 122 LA-419 - Drug Profile 123 lisuride - Drug Profile 124 macitentan - Drug Profile 126 Mydicar - Drug Profile 129 Oligonucleotide to Inhibit Endothelin-1 for Pulmonary Arterial Hypertension - Drug Profile 131 Oligonucleotide to Inhibit MicroRNA-145 for Pulmonary Arterial Hypertension - Drug Profile 132 PB-1046 - Drug Profile 133 PB-1120 - Drug Profile 135 Peptide to Antagonize Urotensin-II Receptor for PAH - Drug Profile 136 PGC-VIP - Drug Profile 137 PK-10453 - Drug Profile 138 R-190 - Drug Profile 139 R-197 - Drug Profile 141 ralinepag - Drug Profile 142 RGN-352 - Drug Profile 143 riociguat - Drug Profile 145 RNAi Oligonucleotide to Inhibit miR-145 for PAH - Drug Profile 148 selegiline + PDE-5 Inhibitor - Drug Profile 149 selexipag - Drug Profile 150 Small Molecule for Pulmonary Arterial Hypertension - Drug Profile 152 Small Molecule to Antagonize Notch Receptor for Pulmonary Arterial Hypertension and Hypoxia - Drug Profile 153 Small Molecule to Inhibit Arginase for Vascular Dysfunction, PAH and Erectile Dysfunction - Drug Profile 154 Small Molecule to Inhibit Myosin for COPD, Asthma And Pulmonary Arterial Hypertension - Drug Profile 156 Small Molecule to Inhibit Soluble Epoxide Hydrolase for Pulmonary Arterial Hypertension - Drug Profile 157 Small Molecules to Activate ACE2 for Pulmonary Arterial Hypertension - Drug Profile 158 Small Molecules to Antagonize 5-HT1B for Pulmonary Arterial Hypertension - Drug Profile 159 Small Molecules to Inhibit MetAP-II for Oncology, Immunology, Infectious Disease, Cardiovascular and Metabolic Disorders - Drug Profile 160 sodium nitrite - Drug Profile 161 Stem Cell Therapy for Cardiovascular Diseases - Drug Profile 163 SUD-004 - Drug Profile 165 Synthetic Peptide to Agonize VPAC2 for Pulmonary Arterial Hypertension - Drug Profile 166 Synthetic Peptide to Inhibit NADPH Oxidase for Pulmonary Hypertension - Drug Profile 167 tadalafil - Drug Profile 168 treprostinil diolamine - Drug Profile 170 TXA-127 - Drug Profile 171 udenafil - Drug Profile 173 VR-876 - Drug Profile 175 Pulmonary Hypertension - Recent Pipeline Updates 176 Pulmonary Hypertension - Dormant Projects 207 Pulmonary Hypertension - Discontinued Products 210 Pulmonary Hypertension - Product Development Milestones 211 Featured News & Press Releases 211 Appendix 220 Methodology 220 Coverage 220 Secondary Research 220 Primary Research 220 Expert Panel Validation 220 Contact Us 220 Disclaimer 221
List of Tables Number of Products under Development for Pulmonary Hypertension, H1 2015 15 Number of Products under Development for Pulmonary Hypertension - Comparative Analysis, H1 2015 16 Number of Products under Development by Companies, H1 2015 18 Number of Products under Development by Companies, H1 2015 (Contd..1) 19 Number of Products under Development by Companies, H1 2015 (Contd..2) 20 Number of Products under Development by Companies, H1 2015 (Contd..3) 21 Number of Products under Investigation by Universities/Institutes, H1 2015 22 Comparative Analysis by Late Stage Development, H1 2015 23 Comparative Analysis by Clinical Stage Development, H1 2015 24 Comparative Analysis by Early Stage Development, H1 2015 25 Products under Development by Companies, H1 2015 26 Products under Development by Companies, H1 2015 (Contd..1) 27 Products under Development by Companies, H1 2015 (Contd..2) 28 Products under Development by Companies, H1 2015 (Contd..3) 29 Products under Development by Companies, H1 2015 (Contd..4) 30 Products under Investigation by Universities/Institutes, H1 2015 31 Pulmonary Hypertension - Pipeline by Actelion Ltd, H1 2015 32 Pulmonary Hypertension - Pipeline by APT Therapeutics, Inc., H1 2015 33 Pulmonary Hypertension - Pipeline by Arena Pharmaceuticals, Inc., H1 2015 34 Pulmonary Hypertension - Pipeline by Asahi Kasei Pharma Corp., H1 2015 35 Pulmonary Hypertension - Pipeline by Ascendis Pharma A/S, H1 2015 36 Pulmonary Hypertension - Pipeline by Bayer AG, H1 2015 37 Pulmonary Hypertension - Pipeline by Bial - Portela & Ca, S.A., H1 2015 38 Pulmonary Hypertension - Pipeline by Biolab Sanus Farmaceutica Ltda., H1 2015 39 Pulmonary Hypertension - Pipeline by Cardioxyl Pharmaceuticals, Inc., H1 2015 40 Pulmonary Hypertension - Pipeline by Carolus Therapeutics, Inc., H1 2015 41 Pulmonary Hypertension - Pipeline by Celladon Corporation, H1 2015 42 Pulmonary Hypertension - Pipeline by Celsion Corporation, H1 2015 43 Pulmonary Hypertension - Pipeline by Corridor Pharmaceuticals Inc., H1 2015 44 Pulmonary Hypertension - Pipeline by Cytokinetics, Inc., H1 2015 45 Pulmonary Hypertension - Pipeline by Eli Lilly and Company, H1 2015 46 Pulmonary Hypertension - Pipeline by Gilead Sciences, Inc., H1 2015 47 Pulmonary Hypertension - Pipeline by HanAll Biopharma Co., Ltd., H1 2015 48 Pulmonary Hypertension - Pipeline by Hanmi Pharmaceuticals, Co. Ltd., H1 2015 49 Pulmonary Hypertension - Pipeline by Ikaria Inc., H1 2015 50 Pulmonary Hypertension - Pipeline by Insmed Incorporated, H1 2015 51 Pulmonary Hypertension - Pipeline by Ironwood Pharmaceuticals, Inc., H1 2015 52 Pulmonary Hypertension - Pipeline by Lacer, S.A., H1 2015 53 Pulmonary Hypertension - Pipeline by Longevity Biotech, Inc, H1 2015 54 Pulmonary Hypertension - Pipeline by LTT Bio-Pharma Co., Ltd., H1 2015 55 Pulmonary Hypertension - Pipeline by Mast Therapeutics, Inc., H1 2015 56 Pulmonary Hypertension - Pipeline by Mezzion Pharma Co. Ltd., H1 2015 57 Pulmonary Hypertension - Pipeline by miRagen Therapeutics, Inc., H1 2015 58 Pulmonary Hypertension - Pipeline by Nippon Shinyaku Co., Ltd., H1 2015 59 Pulmonary Hypertension - Pipeline by Novartis AG, H1 2015 60 Pulmonary Hypertension - Pipeline by PharmaIN Corporation, H1 2015 61 Pulmonary Hypertension - Pipeline by PhaseBio Pharmaceuticals, Inc., H1 2015 62 Pulmonary Hypertension - Pipeline by Pluristem Therapeutics Inc., H1 2015 63 Pulmonary Hypertension - Pipeline by Proteo, Inc., H1 2015 64 Pulmonary Hypertension - Pipeline by Reata Pharmaceuticals, Inc., H1 2015 65 Pulmonary Hypertension - Pipeline by RegeneRx Biopharmaceuticals, Inc., H1 2015 66 Pulmonary Hypertension - Pipeline by Sagene Pharmaceuticals, Inc., H1 2015 67 Pulmonary Hypertension - Pipeline by Silence Therapeutics plc, H1 2015 68 Pulmonary Hypertension - Pipeline by Sinoxa Pharma GmbH, H1 2015 69 Pulmonary Hypertension - Pipeline by Suda Ltd, H1 2015 70 Pulmonary Hypertension - Pipeline by Therametrics holding AG, H1 2015 71 Pulmonary Hypertension - Pipeline by Toray Industries, Inc., H1 2015 72 Pulmonary Hypertension - Pipeline by United Therapeutics Corporation, H1 2015 73 Pulmonary Hypertension - Pipeline by Vectura Group plc, H1 2015 74 Pulmonary Hypertension - Pipeline by Vicore Pharma AB, H1 2015 75 Assessment by Monotherapy Products, H1 2015 76 Assessment by Combination Products, H1 2015 77 Number of Products by Stage and Target, H1 2015 79 Number of Products by Stage and Mechanism of Action, H1 2015 83 Number of Products by Stage and Route of Administration, H1 2015 86 Number of Products by Stage and Molecule Type, H1 2015 88 Pulmonary Hypertension Therapeutics - Recent Pipeline Updates, H1 2015 181 Pulmonary Hypertension - Dormant Projects, H1 2015 212 Pulmonary Hypertension - Dormant Projects (Contd..1), H1 2015 213 Pulmonary Hypertension - Dormant Projects (Contd..2), H1 2015 214 Pulmonary Hypertension - Discontinued Products, H1 2015 215
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