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Paroxysmal Nocturnal Hemoglobinuria - Pipeline Review, H2 2017

Published: Sep, 2017 | Pages: 91 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Paroxysmal Nocturnal Hemoglobinuria - Pipeline Review, H2 2017

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Paroxysmal Nocturnal Hemoglobinuria - Pipeline Review, H2 2017, provides an overview of the Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders) pipeline landscape.

Paroxysmal nocturnal hemoglobinuria is a rare disease in which red blood cells break down earlier than normal. Symptoms include abdominal pain, back pain, dark urine, easy bruising or bleeding, headache and shortness of breath. The predisposing factors include age, obesity and hormone therapy. Treatment includes surgery, chemotherapy and radiation therapy. 

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Paroxysmal Nocturnal Hemoglobinuria - Pipeline Review, H2 2017, provides comprehensive information on the therapeutics under development for Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders) pipeline guide also reviews of key players involved in therapeutic development for Paroxysmal Nocturnal Hemoglobinuria and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 3, 5, 3, 12 and 1 respectively.

Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The pipeline guide provides a snapshot of the global therapeutic landscape of Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders).
- The pipeline guide reviews pipeline therapeutics for Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources. 
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects. 
- The pipeline guide reviews latest news related to pipeline therapeutics for Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders)

Reasons To Buy

- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
 Table of Contents
Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Paroxysmal Nocturnal Hemoglobinuria - Overview 6 Paroxysmal Nocturnal Hemoglobinuria - Therapeutics Development 7 Pipeline Overview 7 Pipeline by Companies 8 Products under Development by Companies 10 Paroxysmal Nocturnal Hemoglobinuria - Therapeutics Assessment 12 Assessment by Target 12 Assessment by Mechanism of Action 14 Assessment by Route of Administration 16 Assessment by Molecule Type 18 Paroxysmal Nocturnal Hemoglobinuria - Companies Involved in Therapeutics Development 20 Achillion Pharmaceuticals Inc 20 Akari Therapeutics Plc 20 Alexion Pharmaceuticals Inc 21 Alnylam Pharmaceuticals Inc 21 Amgen Inc 22 Apellis Pharmaceuticals Inc 22 F. Hoffmann-La Roche Ltd 22 ISU ABXIS Co Ltd 23 Novartis AG 23 NovelMed Therapeutics Inc 24 Omeros Corp 24 Ra Pharmaceuticals Inc 25 Regeneron Pharmaceuticals Inc 25 Regenesance BV 26 Paroxysmal Nocturnal Hemoglobinuria - Drug Profiles 27 ACH-4471 - Drug Profile 27 ACH-5228 - Drug Profile 30 ALN-CC5 - Drug Profile 31 AMY-101 - Drug Profile 35 APL-2 - Drug Profile 37 APL-9 - Drug Profile 40 Coversin - Drug Profile 41 eculizumab biosimilar - Drug Profile 46 eculizumab biosimilar - Drug Profile 47 Gene Therapy for Paroxysmal Nocturnal Hemoglobinuria and Atypical Hemolytic Uremic Syndrome - Drug Profile 48 GNR-045 - Drug Profile 49 Monoclonal Antibody for Paroxysmal Nocturnal Hemoglobinuria - Drug Profile 50 NM-9405 - Drug Profile 51 OMS-721 - Drug Profile 52 OMS-906 - Drug Profile 62 RA-101348 - Drug Profile 63 RA-101495 - Drug Profile 64 ravulizumab - Drug Profile 67 Regenemab - Drug Profile 69 REGN-3918 - Drug Profile 70 RG-6107 - Drug Profile 71 Small Molecule to Inhibit Factor D for C3 glomerulopathy and Paroxysmal Nocturnal Hemoglobinuria - Drug Profile 72 Synthetic Peptide to Inhibit Complement C5 for Autoimmune Disorders, Atypical Hemolytic Uremic Syndrome, Central Nervous System and Paroxysmal Nocturnal Hemoglobinuria - Drug Profile 73 tesidolumab - Drug Profile 74 Paroxysmal Nocturnal Hemoglobinuria - Dormant Projects 76 Paroxysmal Nocturnal Hemoglobinuria - Discontinued Products 77 Paroxysmal Nocturnal Hemoglobinuria - Product Development Milestones 78 Featured News & Press Releases 78 Appendix 88 Methodology 88 Coverage 88 Secondary Research 88 Primary Research 88 Expert Panel Validation 88 Contact Us 88 Disclaimer 89
List of Tables
Number of Products under Development for Paroxysmal Nocturnal Hemoglobinuria, H2 2017 Number of Products under Development by Companies, H2 2017 Products under Development by Companies, H2 2017 Products under Development by Companies, H2 2017 (Contd..1), H2 2017 Number of Products by Stage and Target, H2 2017 Number of Products by Stage and Mechanism of Action, H2 2017 Number of Products by Stage and Route of Administration, H2 2017 Number of Products by Stage and Molecule Type, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Achillion Pharmaceuticals Inc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Akari Therapeutics Plc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Alexion Pharmaceuticals Inc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Alnylam Pharmaceuticals Inc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Amgen Inc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Apellis Pharmaceuticals Inc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by F. Hoffmann-La Roche Ltd, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by ISU ABXIS Co Ltd, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Novartis AG, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by NovelMed Therapeutics Inc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Omeros Corp, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Ra Pharmaceuticals Inc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Regeneron Pharmaceuticals Inc, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Pipeline by Regenesance BV, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Dormant Projects, H2 2017 Paroxysmal Nocturnal Hemoglobinuria - Discontinued Products, H2 2017



                                

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