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Published: Sep, 2014 | Pages:
104 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Ocular Hypertension - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Ocular Hypertension - Pipeline Review, H2 2014', provides an overview of the Ocular Hypertension's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Ocular Hypertension, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Ocular Hypertension and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Ocular Hypertension - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Ocular Hypertension and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Ocular Hypertension products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Ocular Hypertension pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Ocular Hypertension - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Ocular Hypertension pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Ocular Hypertension Overview 9 Therapeutics Development 10 Pipeline Products for Ocular Hypertension - Overview 10 Pipeline Products for Ocular Hypertension - Comparative Analysis 11 Ocular Hypertension - Therapeutics under Development by Companies 12 Ocular Hypertension - Therapeutics under Investigation by Universities/Institutes 14 Ocular Hypertension - Pipeline Products Glance 15 Late Stage Products 15 Clinical Stage Products 16 Early Stage Products 17 Ocular Hypertension - Products under Development by Companies 18 Ocular Hypertension - Products under Investigation by Universities/Institutes 19 Ocular Hypertension - Companies Involved in Therapeutics Development 20 F. Hoffmann-La Roche Ltd. 20 Bausch & Lomb Incorporated 21 Allergan, Inc. 22 Merck & Co., Inc. 23 Santen Pharmaceutical Co., Ltd. 24 Sylentis S.A. 25 Kowa Company, Ltd. 26 Ono Pharmaceutical Co., Ltd. 27 Can-Fite BioPharma Ltd. 28 Asahi Kasei Pharma Corp. 29 Inotek Pharmaceuticals Corporation 30 Aerie Pharmaceuticals, Inc. 31 Otsuka Holdings Co., Ltd. 32 Ocular Therapeutix, Inc. 33 Amakem NV 34 Ocular Hypertension - Therapeutics Assessment 35 Assessment by Monotherapy Products 35 Assessment by Combination Products 36 Assessment by Target 37 Assessment by Mechanism of Action 40 Assessment by Route of Administration 43 Assessment by Molecule Type 45 Drug Profiles 47 tafluprost - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 ripasudil - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 (tafluprost + timolol maleate) - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 latanoprostene bunod - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 AR-13324 - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 OPC-1085EL - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 CF-101 - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 trabodenoson - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 latanoprost - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 SYL-040012 - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 lomerizine - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 RO-5093151 - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 latanoprost - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 AMA-0076 - Drug Profile 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 ONO-9054 - Drug Profile 69 Product Description 69 Mechanism of Action 69 R&D Progress 69 ATS-907 - Drug Profile 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 DE-117 - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 travoprost SR - Drug Profile 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 (bimatoprost + brimonidine tartrate) - Drug Profile 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 (latanoprost + dorzolamide) - Drug Profile 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 LX-7101 - Drug Profile 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 OPA-6566 - Drug Profile 76 Product Description 76 Mechanism of Action 76 R&D Progress 76 latanoprost SR - Drug Profile 77 Product Description 77 Mechanism of Action 77 R&D Progress 77 ATS-8535 - Drug Profile 79 Product Description 79 Mechanism of Action 79 R&D Progress 79 Gene Therapy for Steroid Induced Glaucoma and Ocular Hypertension - Drug Profile 80 Product Description 80 Mechanism of Action 80 R&D Progress 80 Ocular Hypertension - Recent Pipeline Updates 81 Ocular Hypertension - Dormant Projects 95 Ocular Hypertension - Discontinued Products 96 Ocular Hypertension - Product Development Milestones 97 Featured News & Press Releases 97 Aug 15, 2014: Santen Files for Manufacturing/Marketing Approval of its Glaucoma and Ocular Hypertension Therapeutic, COSOPT Mini Combination Ophthalmic Solution 97 Mar 10, 2014: Inotek Pharmaceuticals Initiates Phase 2 Study with Trabodenoson in Combination with Latanoprost for Patients with Glaucoma or Ocular Hypertension 97 Jan 30, 2014: Aerie Pharmaceuticals Initiates Phase 2b Study of PG324, a Novel Fixed-Combination Product to Treat Patients with Glaucoma or Ocular Hypertension 98 Jan 15, 2014: Fish & Richardson Wins Patent Infringement Suit for Allergan Over Generic LUMIGAN 0.01% 99 Dec 20, 2013: Alcon Laboratories Receives CHMP Positive Opinion For Izba 100 Oct 10, 2013: Santen Announces the Launch of TAPROS MINI Ophthalmic Solution 0.0015% for Glaucoma and Ocular Hypertension 100 Sep 20, 2013: Santen Announced Approval for TAPCOM Combination Ophthalmic Solution for the Treatment of Glaucoma and Ocular Hypertension 101 May 03, 2013: Amakem To Present Additional Data On AMA0076 At ARVO Annual Meeting 101 Feb 19, 2013: Sucampo Announces Commercial Availability Of Rescula In US Pharmacies 102 Jan 18, 2013: Santen Pharma Receives Japanese Approval For Tapros Mini Ophthalmic Solution 0.0015% For Glaucoma And Ocular Hypertension Treatment 102 Appendix 103 Methodology 103 Coverage 103 Secondary Research 103 Primary Research 103 Expert Panel Validation 103 Contact Us 104 Disclaimer 104
List of Tables Number of Products under Development for Ocular Hypertension, H2 2014 10 Number of Products under Development for Ocular Hypertension - Comparative Analysis, H2 2014 11 Number of Products under Development by Companies, H2 2014 13 Number of Products under Investigation by Universities/Institutes, H2 2014 14 Comparative Analysis by Late Stage Development, H2 2014 15 Comparative Analysis by Clinical Stage Development, H2 2014 16 Comparative Analysis by Early Stage Development, H2 2014 17 Products under Development by Companies, H2 2014 18 Products under Investigation by Universities/Institutes, H2 2014 19 Ocular Hypertension - Pipeline by F. Hoffmann-La Roche Ltd., H2 2014 20 Ocular Hypertension - Pipeline by Bausch & Lomb Incorporated, H2 2014 21 Ocular Hypertension - Pipeline by Allergan, Inc., H2 2014 22 Ocular Hypertension - Pipeline by Merck & Co., Inc., H2 2014 23 Ocular Hypertension - Pipeline by Santen Pharmaceutical Co., Ltd., H2 2014 24 Ocular Hypertension - Pipeline by Sylentis S.A., H2 2014 25 Ocular Hypertension - Pipeline by Kowa Company, Ltd., H2 2014 26 Ocular Hypertension - Pipeline by Ono Pharmaceutical Co., Ltd., H2 2014 27 Ocular Hypertension - Pipeline by Can-Fite BioPharma Ltd., H2 2014 28 Ocular Hypertension - Pipeline by Asahi Kasei Pharma Corp., H2 2014 29 Ocular Hypertension - Pipeline by Inotek Pharmaceuticals Corporation, H2 2014 30 Ocular Hypertension - Pipeline by Aerie Pharmaceuticals, Inc., H2 2014 31 Ocular Hypertension - Pipeline by Otsuka Holdings Co., Ltd., H2 2014 32 Ocular Hypertension - Pipeline by Ocular Therapeutix, Inc., H2 2014 33 Ocular Hypertension - Pipeline by Amakem NV, H2 2014 34 Assessment by Monotherapy Products, H2 2014 35 Assessment by Combination Products, H2 2014 36 Number of Products by Stage and Target, H2 2014 39 Number of Products by Stage and Mechanism of Action, H2 2014 42 Number of Products by Stage and Route of Administration, H2 2014 44 Number of Products by Stage and Molecule Type, H2 2014 46 Ocular Hypertension Therapeutics - Recent Pipeline Updates, H2 2014 81 Ocular Hypertension - Dormant Projects, H2 2014 95 Ocular Hypertension - Discontinued Products, H2 2014 96
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