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Published: Oct, 2015 | Pages:
285 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Non-Alcoholic Steatohepatitis - Pipeline Review, H2 2015 Summary Global Markets Direct's, 'Non-Alcoholic Steatohepatitis - Pipeline Review, H2 2015', provides an overview of the Non-Alcoholic Steatohepatitis's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Non-Alcoholic Steatohepatitis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Non-Alcoholic Steatohepatitis and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Non-Alcoholic Steatohepatitis - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Non-Alcoholic Steatohepatitis and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Non-Alcoholic Steatohepatitis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Non-Alcoholic Steatohepatitis pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to Buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Non-Alcoholic Steatohepatitis - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Non-Alcoholic Steatohepatitis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents
Table of Contents
2 List of Tables 6 List of Figures 8 Introduction 9 Global Markets Direct Report Coverage 9 Non-Alcoholic Steatohepatitis Overview 10 Therapeutics Development 11 Pipeline Products for Non-Alcoholic Steatohepatitis - Overview 11 Pipeline Products for Non-Alcoholic Steatohepatitis - Comparative Analysis 12 Non-Alcoholic Steatohepatitis - Therapeutics under Development by Companies 13 Non-Alcoholic Steatohepatitis - Therapeutics under Investigation by Universities/Institutes 16 Non-Alcoholic Steatohepatitis - Pipeline Products Glance 17 Late Stage Products 17 Clinical Stage Products 18 Early Stage Products 19 Non-Alcoholic Steatohepatitis - Products under Development by Companies 20 Non-Alcoholic Steatohepatitis - Products under Investigation by Universities/Institutes 25 Non-Alcoholic Steatohepatitis - Companies Involved in Therapeutics Development 26 AlbireoPharma 26 Aquinox Pharmaceuticals Inc. 27 Ardelyx, Inc. 28 Arisaph Pharmaceuticals, Inc. 29 BiOrion Technologies B.V. 30 Boehringer Ingelheim GmbH 31 Bristol-Myers Squibb Company 32 Cardax Pharmaceuticals, Inc. 33 Cerenis Therapeutics Holding SA 34 Conatus Pharmaceuticals Inc. 35 Connexios Life Sciences Pvt. Ltd. 36 Daiichi Sankyo Company, Limited 37 Dr. Falk Pharma GmbH 38 DURECT Corporation 39 Dynavax Technologies Corporation 40 Enanta Pharmaceuticals, Inc. 41 Exicure, Inc. 42 Galectin Therapeutics, Inc. 43 Galmed International Ltd. 44 Genfit SA 45 GenKyoTex S.A. 46 Gilead Sciences, Inc. 47 iCo Therapeutics Inc. 48 Immuron Limited 49 Intercept Pharmaceuticals, Inc. 50 Isis Pharmaceuticals, Inc. 51 Jenrin Discovery, Inc. 52 Kissei Pharmaceutical Co., Ltd. 53 Kyorin Pharmaceutical Co., Ltd. 54 Merck & Co., Inc. 55 Mochida Pharmaceutical Co., Ltd. 56 NGM Biopharmaceuticals, Inc. 57 Nimbus Therapeutics, LLC 58 Nippon Chemiphar Co., Ltd. 59 Novartis AG 60 Novo Nordisk A/S 61 ProMetic Life Sciences Inc. 62 Protalix BioTherapeutics, Inc. 63 Regulus Therapeutics Inc. 64 RuiYi Inc. 65 Shire Plc 66 Stelic Institute & Co. 67 Therapix Biosciences Ltd 68 Tobira Therapeutics, Inc. 69 Vascular Biogenics Ltd. 70 Verva Pharmaceuticals Limited 71 Viking Therapeutics, Inc. 72 Virobay Inc. 73 Zafgen Inc. 74 Zydus Cadila Healthcare Limited 75 Non-Alcoholic Steatohepatitis - Therapeutics Assessment 76 Assessment by Monotherapy Products 76 Assessment by Combination Products 77 Assessment by Target 78 Assessment by Mechanism of Action 82 Assessment by Route of Administration 85 Assessment by Molecule Type 87 Drug Profiles 89 (leucine + metformin + sildenafil) - Drug Profile 89 A-4250 - Drug Profile 90 AM-0010 - Drug Profile 91 AQX-1125 - Drug Profile 92 Aramchol - Drug Profile 94 ARI-3037MO - Drug Profile 96 bertilimumab - Drug Profile 97 BMS-986036 - Drug Profile 99 BOT-191 - Drug Profile 101 CDX-085 - Drug Profile 102 cenicriviroc mesylate - Drug Profile 104 CER-209 - Drug Profile 106 CNX-014 - Drug Profile 107 CNX-023 - Drug Profile 108 CNX-024 - Drug Profile 109 CNX-025 - Drug Profile 110 DUR-928 - Drug Profile 111 DV-1179 - Drug Profile 112 elafibranor - Drug Profile 114 emricasan - Drug Profile 117 etanercept biosimilar - Drug Profile 119 GKT-831 - Drug Profile 120 GR-MD-02 - Drug Profile 121 icosapent ethyl - Drug Profile 124 IMM-124E - Drug Profile 125 ISIS-DGAT2Rx - Drug Profile 127 JD-5037 - Drug Profile 128 JKB-119 - Drug Profile 129 JKB-121 - Drug Profile 130 liraglutide (recombinant) - Drug Profile 131 LJN-452 - Drug Profile 134 MAT-8800 - Drug Profile 135 methazolamide - Drug Profile 136 MGL-3196 - Drug Profile 138 Monoclonal Antibody to Inhibit CD3 for Autoimmune Disorders, CNS Disorders, Infectious Diseases, Liver Diseases, Metabolic Disorders and Cardiovascular Diseases - Drug Profile 140 NC-101 - Drug Profile 142 NC-2400 - Drug Profile 143 ND-630 - Drug Profile 144 ND-654 - Drug Profile 145 NDI-010976 - Drug Profile 146 NGM-282 - Drug Profile 147 norursodeoxycholic acid - Drug Profile 148 NP-201 - Drug Profile 149 obeticholic acid - Drug Profile 150 Oligonucleotides for Non-Alcoholic Steatohepatitis - Drug Profile 153 PBI-4050 - Drug Profile 154 pentamidine isethionate - Drug Profile 155 Px-102 - Drug Profile 157 Px-103 - Drug Profile 159 PXS-4728A - Drug Profile 160 PZ-235 - Drug Profile 161 RDX-009 - Drug Profile 162 remogliflozin etabonate - Drug Profile 163 RG-125 - Drug Profile 166 RYI-018 - Drug Profile 167 saroglitazar - Drug Profile 168 SDP-051 - Drug Profile 169 selonsertib - Drug Profile 171 simtuzumab - Drug Profile 172 Small Molecule for Non-Alcoholic Steatohepatitis - Drug Profile 174 Small Molecule to Inhibit SCD-1 for Nonalcoholic Steatohepatitis - Drug Profile 175 Small Molecules to Activate AMPK for Fatty Liver Disease - Drug Profile 176 Small Molecules to Agonize Farnesoid X Receptor for Non-alcoholic Steatohepatitis and Primary Biliary Cirrhosis - Drug Profile 177 solithromycin - Drug Profile 178 SR-9238 - Drug Profile 180 STNM-09 - Drug Profile 181 TGFTX-3 Program - Drug Profile 182 tipelukast - Drug Profile 183 TRX-318 - Drug Profile 185 VB-201 - Drug Profile 186 VBY-376 - Drug Profile 188 VK-0214 - Drug Profile 189 VK-2809 - Drug Profile 190 volixibat potassium - Drug Profile 192 VVP-100-X - Drug Profile 193 ZGN-839 - Drug Profile 194 Non-Alcoholic Steatohepatitis - Recent Pipeline Updates 195 Non-Alcoholic Steatohepatitis - Dormant Projects 268 Non-Alcoholic Steatohepatitis - Discontinued Products 270 Non-Alcoholic Steatohepatitis - Product Development Milestones 271 Featured News & Press Releases 271 Appendix 278 Methodology 278 Coverage 278 Secondary Research 278 Primary Research 278 Expert Panel Validation 278 Contact Us 278 Disclaimer 279
List of Tables
Number of Products under Development for Non-Alcoholic Steatohepatitis, H2 2015 17 Number of Products under Development for Non-Alcoholic Steatohepatitis - Comparative Analysis, H2 2015 18 Number of Products under Development by Companies, H2 2015 20 Number of Products under Investigation by Universities/Institutes, H2 2015 22 Comparative Analysis by Late Stage Development, H2 2015 23 Comparative Analysis by Clinical Stage Development, H2 2015 24 Comparative Analysis by Early Stage Development, H2 2015 25 Products under Development by Companies, H2 2015 26 Products under Development by Companies, H2 2015 (Contd..1) 27 Products under Development by Companies, H2 2015 (Contd..2) 28 Products under Development by Companies, H2 2015 (Contd..3) 29 Products under Development by Companies, H2 2015 (Contd..4) 30 Products under Investigation by Universities/Institutes, H2 2015 31 Non-Alcoholic Steatohepatitis - Pipeline by AlbireoPharma, H2 2015 32 Non-Alcoholic Steatohepatitis - Pipeline by Aquinox Pharmaceuticals Inc., H2 2015 33 Non-Alcoholic Steatohepatitis - Pipeline by Ardelyx, Inc., H2 2015 34 Non-Alcoholic Steatohepatitis - Pipeline by Arisaph Pharmaceuticals, Inc., H2 2015 35 Non-Alcoholic Steatohepatitis - Pipeline by BiOrion Technologies B.V., H2 2015 36 Non-Alcoholic Steatohepatitis - Pipeline by Boehringer Ingelheim GmbH, H2 2015 37 Non-Alcoholic Steatohepatitis - Pipeline by Bristol-Myers Squibb Company, H2 2015 38 Non-Alcoholic Steatohepatitis - Pipeline by Cardax Pharmaceuticals, Inc., H2 2015 39 Non-Alcoholic Steatohepatitis - Pipeline by Cerenis Therapeutics Holding SA, H2 2015 40 Non-Alcoholic Steatohepatitis - Pipeline by Conatus Pharmaceuticals Inc., H2 2015 41 Non-Alcoholic Steatohepatitis - Pipeline by Connexios Life Sciences Pvt. Ltd., H2 2015 42 Non-Alcoholic Steatohepatitis - Pipeline by Daiichi Sankyo Company, Limited, H2 2015 43 Non-Alcoholic Steatohepatitis - Pipeline by Dr. Falk Pharma GmbH, H2 2015 44 Non-Alcoholic Steatohepatitis - Pipeline by DURECT Corporation, H2 2015 45 Non-Alcoholic Steatohepatitis - Pipeline by Dynavax Technologies Corporation, H2 2015 46 Non-Alcoholic Steatohepatitis - Pipeline by Enanta Pharmaceuticals, Inc., H2 2015 47 Non-Alcoholic Steatohepatitis - Pipeline by Exicure, Inc., H2 2015 48 Non-Alcoholic Steatohepatitis - Pipeline by Galectin Therapeutics, Inc., H2 2015 49 Non-Alcoholic Steatohepatitis - Pipeline by Galmed International Ltd., H2 2015 50 Non-Alcoholic Steatohepatitis - Pipeline by Genfit SA, H2 2015 51 Non-Alcoholic Steatohepatitis - Pipeline by GenKyoTex S.A., H2 2015 52 Non-Alcoholic Steatohepatitis - Pipeline by Gilead Sciences, Inc., H2 2015 53 Non-Alcoholic Steatohepatitis - Pipeline by iCo Therapeutics Inc., H2 2015 54 Non-Alcoholic Steatohepatitis - Pipeline by Immuron Limited, H2 2015 55 Non-Alcoholic Steatohepatitis - Pipeline by Intercept Pharmaceuticals, Inc., H2 2015 56 Non-Alcoholic Steatohepatitis - Pipeline by Isis Pharmaceuticals, Inc., H2 2015 57 Non-Alcoholic Steatohepatitis - Pipeline by Jenrin Discovery, Inc., H2 2015 58 Non-Alcoholic Steatohepatitis - Pipeline by Kissei Pharmaceutical Co., Ltd., H2 2015 59 Non-Alcoholic Steatohepatitis - Pipeline by Kyorin Pharmaceutical Co., Ltd., H2 2015 60 Non-Alcoholic Steatohepatitis - Pipeline by Merck & Co., Inc., H2 2015 61 Non-Alcoholic Steatohepatitis - Pipeline by Mochida Pharmaceutical Co., Ltd., H2 2015 62 Non-Alcoholic Steatohepatitis - Pipeline by NGM Biopharmaceuticals, Inc., H2 2015 63 Non-Alcoholic Steatohepatitis - Pipeline by Nimbus Therapeutics, LLC, H2 2015 64 Non-Alcoholic Steatohepatitis - Pipeline by Nippon Chemiphar Co., Ltd., H2 2015 65 Non-Alcoholic Steatohepatitis - Pipeline by Novartis AG, H2 2015 66 Non-Alcoholic Steatohepatitis - Pipeline by Novo Nordisk A/S, H2 2015 67 Non-Alcoholic Steatohepatitis - Pipeline by ProMetic Life Sciences Inc., H2 2015 68 Non-Alcoholic Steatohepatitis - Pipeline by Protalix BioTherapeutics, Inc., H2 2015 69 Non-Alcoholic Steatohepatitis - Pipeline by Regulus Therapeutics Inc., H2 2015 70 Non-Alcoholic Steatohepatitis - Pipeline by RuiYi Inc., H2 2015 71 Non-Alcoholic Steatohepatitis - Pipeline by Shire Plc, H2 2015 72 Non-Alcoholic Steatohepatitis - Pipeline by Stelic Institute & Co., H2 2015 73 Non-Alcoholic Steatohepatitis - Pipeline by Therapix Biosciences Ltd, H2 2015 74 Non-Alcoholic Steatohepatitis - Pipeline by Tobira Therapeutics, Inc., H2 2015 75 Non-Alcoholic Steatohepatitis - Pipeline by Vascular Biogenics Ltd., H2 2015 76 Non-Alcoholic Steatohepatitis - Pipeline by Verva Pharmaceuticals Limited, H2 2015 77 Non-Alcoholic Steatohepatitis - Pipeline by Viking Therapeutics, Inc., H2 2015 78 Non-Alcoholic Steatohepatitis - Pipeline by Virobay Inc., H2 2015 79 Non-Alcoholic Steatohepatitis - Pipeline by Zafgen Inc., H2 2015 80 Non-Alcoholic Steatohepatitis - Pipeline by Zydus Cadila Healthcare Limited, H2 2015 81 Assessment by Monotherapy Products, H2 2015 82 Assessment by Combination Products, H2 2015 83 Number of Products by Stage and Target, H2 2015 85 Number of Products by Stage and Mechanism of Action, H2 2015 89 Number of Products by Stage and Route of Administration, H2 2015 92 Number of Products by Stage and Molecule Type, H2 2015 94 Non-Alcoholic Steatohepatitis Therapeutics - Recent Pipeline Updates, H2 2015 201 Non-Alcoholic Steatohepatitis - Dormant Projects, H2 2015 274 Non-Alcoholic Steatohepatitis - Dormant Projects (Contd..1), H2 2015 275 Non-Alcoholic Steatohepatitis - Discontinued Products, H2 2015 276
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