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Published: Feb, 2016 | Pages:
345 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Non-Alcoholic Steatohepatitis - Pipeline Review, H1 2016 Summary Global Markets Direct's, 'Non-Alcoholic Steatohepatitis - Pipeline Review, H1 2016', provides an overview of the Non-Alcoholic Steatohepatitis pipeline landscape. The report provides comprehensive information on the therapeutics under development for Non-Alcoholic Steatohepatitis, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Non-Alcoholic Steatohepatitis and features dormant and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data. Scope - The report provides a snapshot of the global therapeutic landscape of Non-Alcoholic Steatohepatitis - The report reviews pipeline therapeutics for Non-Alcoholic Steatohepatitis by companies and universities/research institutes based on information derived from company and industry-specific sources - The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages - The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved Non-Alcoholic Steatohepatitis therapeutics and enlists all their major and minor projects - The report assesses Non-Alcoholic Steatohepatitis therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type - The report summarizes all the dormant and discontinued pipeline projects - The report reviews latest news related to pipeline therapeutics for Non-Alcoholic Steatohepatitis Reasons to Buy - Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Identify and understand important and diverse types of therapeutics under development for Non-Alcoholic Steatohepatitis - Identify potential new clients or partners in the target demographic - Develop strategic initiatives by understanding the focus areas of leading companies - Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics - Devise corrective measures for pipeline projects by understanding Non-Alcoholic Steatohepatitis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 7 List of Figures 9 Introduction 10 Global Markets Direct Report Coverage 10 Non-Alcoholic Steatohepatitis Overview 11 Therapeutics Development 12 Pipeline Products for Non-Alcoholic Steatohepatitis - Overview 12 Pipeline Products for Non-Alcoholic Steatohepatitis - Comparative Analysis 13 Non-Alcoholic Steatohepatitis - Therapeutics under Development by Companies 14 Non-Alcoholic Steatohepatitis - Therapeutics under Investigation by Universities/Institutes 19 Non-Alcoholic Steatohepatitis - Pipeline Products Glance 20 Late Stage Products 20 Clinical Stage Products 21 Early Stage Products 22 Non-Alcoholic Steatohepatitis - Products under Development by Companies 23 Non-Alcoholic Steatohepatitis - Products under Investigation by Universities/Institutes 29 Non-Alcoholic Steatohepatitis - Companies Involved in Therapeutics Development 30 AlbireoPharma 30 Alnylam Pharmaceuticals, Inc. 31 Aquinox Pharmaceuticals Inc. 32 Arbutus Biopharma Corporation 33 Arisaph Pharmaceuticals, Inc. 34 AstraZeneca Plc 35 BiOrion Technologies B.V. 36 Bird Rock Bio, Inc. 37 Boehringer Ingelheim GmbH 38 Bristol-Myers Squibb Company 39 Can-Fite BioPharma Ltd. 40 Cardax Pharmaceuticals, Inc. 41 Cerenis Therapeutics Holding SA 42 Conatus Pharmaceuticals Inc. 43 Connexios Life Sciences Pvt. Ltd. 44 Daiichi Sankyo Company, Limited 45 Dr. Falk Pharma GmbH 46 DURECT Corporation 47 Dynavax Technologies Corporation 48 Enanta Pharmaceuticals, Inc. 49 Exicure, Inc. 50 F. Hoffmann-La Roche Ltd. 51 Galectin Therapeutics, Inc. 52 Galmed Pharmaceuticals Ltd. 53 Genfit SA 54 GenKyoTex S.A. 55 Gilead Sciences, Inc. 56 Immuron Limited 57 Intercept Pharmaceuticals, Inc. 58 Inventiva SAS 59 Ionis Pharmaceuticals, Inc. 60 Jenrin Discovery, Inc. 61 Kissei Pharmaceutical Co., Ltd. 62 Kyorin Pharmaceutical Co., Ltd. 63 Medivation, Inc. 64 Merck & Co., Inc. 65 Metabolic Solutions Development Company, LLC 66 Naia Limited 67 NGM Biopharmaceuticals, Inc. 68 Nimbus Therapeutics, LLC 69 Nippon Chemiphar Co., Ltd. 70 Nitto Denko Corporation 71 Novartis AG 72 NovaTarg Therapeutics, Inc 73 Novo Nordisk A/S 74 Pharmaxis Limited 75 Promethera Biosciences S.A. 76 ProMetic Life Sciences Inc. 77 Protalix BioTherapeutics, Inc. 78 Regulus Therapeutics Inc. 79 Shire Plc 80 Stelic Institute & Co., Inc. 81 TaiwanJ Pharmaceuticals Co., Ltd. 82 Therapix Biosciences Ltd 83 Tobira Therapeutics, Inc. 84 Vascular Biogenics Ltd. 85 Verlyx Pharma Inc. 86 Verva Pharmaceuticals Limited 87 Viking Therapeutics, Inc. 88 Virobay Inc. 89 Zafgen Inc. 90 Zydus Cadila Healthcare Limited 91 Non-Alcoholic Steatohepatitis - Therapeutics Assessment 92 Assessment by Monotherapy Products 92 Assessment by Combination Products 93 Assessment by Target 94 Assessment by Mechanism of Action 99 Assessment by Route of Administration 103 Assessment by Molecule Type 105 Drug Profiles 107 (leucine + metformin hydrochloride + sildenafil citrate) - Drug Profile 107 (leucine + PDE5 Inhibitor) - Drug Profile 108 A-4250 - Drug Profile 109 AM-0010 - Drug Profile 110 AQX-1125 - Drug Profile 112 Aramchol - Drug Profile 115 ARI-3037MO - Drug Profile 118 bertilimumab - Drug Profile 120 BMS-986036 - Drug Profile 122 BMS-986171 - Drug Profile 124 BOT-191 - Drug Profile 125 CDX-085 - Drug Profile 126 cenicriviroc mesylate - Drug Profile 128 CER-209 - Drug Profile 130 CF-102 - Drug Profile 131 CNX-014 - Drug Profile 133 CNX-023 - Drug Profile 134 CNX-024 - Drug Profile 135 CNX-025 - Drug Profile 136 DRX-065 - Drug Profile 137 DUR-928 - Drug Profile 138 DV-1179 - Drug Profile 140 EDP-305 - Drug Profile 142 elafibranor - Drug Profile 143 emricasan - Drug Profile 146 etanercept biosimilar - Drug Profile 148 GKT-831 - Drug Profile 149 GRMD-02 - Drug Profile 150 GS-9674 - Drug Profile 153 HepaStem - Drug Profile 155 IMM-124E - Drug Profile 157 IONIS-DGAT2Rx - Drug Profile 159 IVA-337 - Drug Profile 160 JD-5037 - Drug Profile 161 JKB-119 - Drug Profile 162 JKB-121 - Drug Profile 163 linagliptin - Drug Profile 164 liraglutide (recombinant) - Drug Profile 165 LJN-452 - Drug Profile 168 MAT-8800 - Drug Profile 169 MDV-4463 - Drug Profile 170 methazolamide - Drug Profile 171 Monoclonal Antibody to Inhibit CD3 for Cardiovascular, CNS, Gastrointestinal, Immunological, Metabolic and Infectious Diseases - Drug Profile 173 MSDC-0602 - Drug Profile 175 NC-101 - Drug Profile 177 NC-2400 - Drug Profile 178 ND-630 - Drug Profile 179 ND-654 - Drug Profile 180 ND-L02s0201 - Drug Profile 182 NDI-010976 - Drug Profile 184 NGM-282 - Drug Profile 185 norursodeoxycholic acid - Drug Profile 187 NP-201 - Drug Profile 189 obeticholic acid - Drug Profile 190 Oligonucleotides for Non-Alcoholic Steatohepatitis - Drug Profile 193 PBI-4050 - Drug Profile 194 pentamidine isethionate - Drug Profile 196 Px-103 - Drug Profile 198 PXS-4728A - Drug Profile 199 PXS-5033A - Drug Profile 200 PZ-235 - Drug Profile 201 remogliflozin etabonate - Drug Profile 202 RG-125 - Drug Profile 205 RG-6125 - Drug Profile 206 RNAi Oligonucleotides for NASH, Cardiovascular and Metabolic Disorders - Drug Profile 208 RYI-018 - Drug Profile 209 saroglitazar - Drug Profile 210 selonsertib - Drug Profile 211 simtuzumab - Drug Profile 212 Small Molecule for Non-Alcoholic Steatohepatitis - Drug Profile 214 Small Molecule for Non-Alcoholic Steatohepatitis and Non-Alcoholic Fatty Liver Disease - Drug Profile 215 Small Molecule to Inhibit SCD-1 for Nonalcoholic Steatohepatitis - Drug Profile 216 Small Molecules to Activate AMPK for Fatty Liver Disease - Drug Profile 217 Small Molecules to Inhibit MLK3 for Non-Alcoholic Steatohepatitis - Drug Profile 218 solithromycin - Drug Profile 219 SR-9238 - Drug Profile 222 STNM-09 - Drug Profile 223 TGFTX-3 - Drug Profile 224 tipelukast - Drug Profile 225 TKM-HTG - Drug Profile 227 TRX-318 - Drug Profile 228 VB-201 - Drug Profile 229 VBY-376 - Drug Profile 231 VK-0214 - Drug Profile 232 VK-2809 - Drug Profile 233 volixibat potassium - Drug Profile 235 VVP-100-X - Drug Profile 236 ZGN-839 - Drug Profile 237 Non-Alcoholic Steatohepatitis - Recent Pipeline Updates 238 Non-Alcoholic Steatohepatitis - Dormant Projects 327 Non-Alcoholic Steatohepatitis - Discontinued Products 329 Non-Alcoholic Steatohepatitis - Product Development Milestones 330 Featured News & Press Releases 330 Appendix 338 Methodology 338 Coverage 338 Secondary Research 338 Primary Research 338 Expert Panel Validation 338 Contact Us 338 Disclaimer 339
List of Tables Number of Products under Development for Non-Alcoholic Steatohepatitis, H1 2016 18 Number of Products under Development for Non-Alcoholic Steatohepatitis - Comparative Analysis, H1 2016 19 Number of Products under Development by Companies, H1 2016 20 Number of Products under Development by Companies, H1 2016 (Contd..1) 21 Number of Products under Development by Companies, H1 2016 (Contd..2) 22 Number of Products under Development by Companies, H1 2016 (Contd..3) 23 Number of Products under Development by Companies, H1 2016 (Contd..4) 24 Number of Products under Investigation by Universities/Institutes, H1 2016 25 Comparative Analysis by Late Stage Development, H1 2016 26 Comparative Analysis by Clinical Stage Development, H1 2016 27 Comparative Analysis by Early Stage Development, H1 2016 28 Products under Development by Companies, H1 2016 29 Products under Development by Companies, H1 2016 (Contd..1) 30 Products under Development by Companies, H1 2016 (Contd..2) 31 Products under Development by Companies, H1 2016 (Contd..3) 32 Products under Development by Companies, H1 2016 (Contd..4) 33 Products under Development by Companies, H1 2016 (Contd..5) 34 Products under Investigation by Universities/Institutes, H1 2016 35 Non-Alcoholic Steatohepatitis - Pipeline by AlbireoPharma, H1 2016 36 Non-Alcoholic Steatohepatitis - Pipeline by Alnylam Pharmaceuticals, Inc., H1 2016 37 Non-Alcoholic Steatohepatitis - Pipeline by Aquinox Pharmaceuticals Inc., H1 2016 38 Non-Alcoholic Steatohepatitis - Pipeline by Arbutus Biopharma Corporation, H1 2016 39 Non-Alcoholic Steatohepatitis - Pipeline by Arisaph Pharmaceuticals, Inc., H1 2016 40 Non-Alcoholic Steatohepatitis - Pipeline by AstraZeneca Plc, H1 2016 41 Non-Alcoholic Steatohepatitis - Pipeline by BiOrion Technologies B.V., H1 2016 42 Non-Alcoholic Steatohepatitis - Pipeline by Bird Rock Bio, Inc., H1 2016 43 Non-Alcoholic Steatohepatitis - Pipeline by Boehringer Ingelheim GmbH, H1 2016 44 Non-Alcoholic Steatohepatitis - Pipeline by Bristol-Myers Squibb Company, H1 2016 45 Non-Alcoholic Steatohepatitis - Pipeline by Can-Fite BioPharma Ltd., H1 2016 46 Non-Alcoholic Steatohepatitis - Pipeline by Cardax Pharmaceuticals, Inc., H1 2016 47 Non-Alcoholic Steatohepatitis - Pipeline by Cerenis Therapeutics Holding SA, H1 2016 48 Non-Alcoholic Steatohepatitis - Pipeline by Conatus Pharmaceuticals Inc., H1 2016 49 Non-Alcoholic Steatohepatitis - Pipeline by Connexios Life Sciences Pvt. Ltd., H1 2016 50 Non-Alcoholic Steatohepatitis - Pipeline by Daiichi Sankyo Company, Limited, H1 2016 51 Non-Alcoholic Steatohepatitis - Pipeline by Dr. Falk Pharma GmbH, H1 2016 52 Non-Alcoholic Steatohepatitis - Pipeline by DURECT Corporation, H1 2016 53 Non-Alcoholic Steatohepatitis - Pipeline by Dynavax Technologies Corporation, H1 2016 54 Non-Alcoholic Steatohepatitis - Pipeline by Enanta Pharmaceuticals, Inc., H1 2016 55 Non-Alcoholic Steatohepatitis - Pipeline by Exicure, Inc., H1 2016 56 Non-Alcoholic Steatohepatitis - Pipeline by F. Hoffmann-La Roche Ltd., H1 2016 57 Non-Alcoholic Steatohepatitis - Pipeline by Galectin Therapeutics, Inc., H1 2016 58 Non-Alcoholic Steatohepatitis - Pipeline by Galmed Pharmaceuticals Ltd., H1 2016 59 Non-Alcoholic Steatohepatitis - Pipeline by Genfit SA, H1 2016 60 Non-Alcoholic Steatohepatitis - Pipeline by GenKyoTex S.A., H1 2016 61 Non-Alcoholic Steatohepatitis - Pipeline by Gilead Sciences, Inc., H1 2016 62 Non-Alcoholic Steatohepatitis - Pipeline by Immuron Limited, H1 2016 63 Non-Alcoholic Steatohepatitis - Pipeline by Intercept Pharmaceuticals, Inc., H1 2016 64 Non-Alcoholic Steatohepatitis - Pipeline by Inventiva SAS, H1 2016 65 Non-Alcoholic Steatohepatitis - Pipeline by Ionis Pharmaceuticals, Inc., H1 2016 66 Non-Alcoholic Steatohepatitis - Pipeline by Jenrin Discovery, Inc., H1 2016 67 Non-Alcoholic Steatohepatitis - Pipeline by Kissei Pharmaceutical Co., Ltd., H1 2016 68 Non-Alcoholic Steatohepatitis - Pipeline by Kyorin Pharmaceutical Co., Ltd., H1 2016 69 Non-Alcoholic Steatohepatitis - Pipeline by Medivation, Inc., H1 2016 70 Non-Alcoholic Steatohepatitis - Pipeline by Merck & Co., Inc., H1 2016 71 Non-Alcoholic Steatohepatitis - Pipeline by Metabolic Solutions Development Company, LLC, H1 2016 72 Non-Alcoholic Steatohepatitis - Pipeline by Naia Limited, H1 2016 73 Non-Alcoholic Steatohepatitis - Pipeline by NGM Biopharmaceuticals, Inc., H1 2016 74 Non-Alcoholic Steatohepatitis - Pipeline by Nimbus Therapeutics, LLC, H1 2016 75 Non-Alcoholic Steatohepatitis - Pipeline by Nippon Chemiphar Co., Ltd., H1 2016 76 Non-Alcoholic Steatohepatitis - Pipeline by Nitto Denko Corporation, H1 2016 77 Non-Alcoholic Steatohepatitis - Pipeline by Novartis AG, H1 2016 78 Non-Alcoholic Steatohepatitis - Pipeline by NovaTarg Therapeutics, Inc, H1 2016 79 Non-Alcoholic Steatohepatitis - Pipeline by Novo Nordisk A/S, H1 2016 80 Non-Alcoholic Steatohepatitis - Pipeline by Pharmaxis Limited, H1 2016 81 Non-Alcoholic Steatohepatitis - Pipeline by Promethera Biosciences S.A., H1 2016 82 Non-Alcoholic Steatohepatitis - Pipeline by ProMetic Life Sciences Inc., H1 2016 83 Non-Alcoholic Steatohepatitis - Pipeline by Protalix BioTherapeutics, Inc., H1 2016 84 Non-Alcoholic Steatohepatitis - Pipeline by Regulus Therapeutics Inc., H1 2016 85 Non-Alcoholic Steatohepatitis - Pipeline by Shire Plc, H1 2016 86 Non-Alcoholic Steatohepatitis - Pipeline by Stelic Institute & Co., Inc., H1 2016 87 Non-Alcoholic Steatohepatitis - Pipeline by TaiwanJ Pharmaceuticals Co., Ltd., H1 2016 88 Non-Alcoholic Steatohepatitis - Pipeline by Therapix Biosciences Ltd, H1 2016 89 Non-Alcoholic Steatohepatitis - Pipeline by Tobira Therapeutics, Inc., H1 2016 90 Non-Alcoholic Steatohepatitis - Pipeline by Vascular Biogenics Ltd., H1 2016 91 Non-Alcoholic Steatohepatitis - Pipeline by Verlyx Pharma Inc., H1 2016 92 Non-Alcoholic Steatohepatitis - Pipeline by Verva Pharmaceuticals Limited, H1 2016 93 Non-Alcoholic Steatohepatitis - Pipeline by Viking Therapeutics, Inc., H1 2016 94 Non-Alcoholic Steatohepatitis - Pipeline by Virobay Inc., H1 2016 95 Non-Alcoholic Steatohepatitis - Pipeline by Zafgen Inc., H1 2016 96 Non-Alcoholic Steatohepatitis - Pipeline by Zydus Cadila Healthcare Limited, H1 2016 97 Assessment by Monotherapy Products, H1 2016 98 Assessment by Combination Products, H1 2016 99 Number of Products by Stage and Target, H1 2016 101 Number of Products by Stage and Mechanism of Action, H1 2016 106 Number of Products by Stage and Route of Administration, H1 2016 110 Number of Products by Stage and Molecule Type, H1 2016 112 Non-Alcoholic Steatohepatitis Therapeutics - Recent Pipeline Updates, H1 2016 244 Non-Alcoholic Steatohepatitis - Dormant Projects, H1 2016 333 Non-Alcoholic Steatohepatitis - Dormant Projects (Contd..1), H1 2016 334 Non-Alcoholic Steatohepatitis - Discontinued Products, H1 2016 335
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