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Published: Jul, 2014 | Pages:
79 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Nasopharyngeal Cancer - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Nasopharyngeal Cancer - Pipeline Review, H2 2014', provides an overview of the Nasopharyngeal Cancer's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Nasopharyngeal Cancer, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Nasopharyngeal Cancer and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Nasopharyngeal Cancer - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Nasopharyngeal Cancer and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Nasopharyngeal Cancer products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Nasopharyngeal Cancer pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Nasopharyngeal Cancer - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Nasopharyngeal Cancer pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Nasopharyngeal Cancer Overview 8 Therapeutics Development 9 Pipeline Products for Nasopharyngeal Cancer - Overview 9 Pipeline Products for Nasopharyngeal Cancer - Comparative Analysis 10 Nasopharyngeal Cancer - Therapeutics under Development by Companies 11 Nasopharyngeal Cancer - Therapeutics under Investigation by Universities/Institutes 13 Nasopharyngeal Cancer - Pipeline Products Glance 15 Late Stage Products 15 Clinical Stage Products 16 Early Stage Products 17 Nasopharyngeal Cancer - Products under Development by Companies 18 Nasopharyngeal Cancer - Products under Investigation by Universities/Institutes 19 Nasopharyngeal Cancer - Companies Involved in Therapeutics Development 20 F. Hoffmann-La Roche Ltd. 20 Gilead Sciences, Inc. 21 Astex Pharmaceuticals, Inc. 22 Cyclacel Pharmaceuticals, Inc. 23 BioDiem Ltd 24 Pharmacyclics, Inc. 25 Ambrx, Inc. 26 Otsuka Holdings Co., Ltd. 27 National Cancer Centre Singapore 28 Nasopharyngeal Cancer - Therapeutics Assessment 29 Assessment by Monotherapy Products 29 Assessment by Combination Products 30 Assessment by Target 31 Assessment by Mechanism of Action 34 Assessment by Route of Administration 37 Assessment by Molecule Type 39 Drug Profiles 41 nimotuzumab - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 seliciclib - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 Autologous Epstein-Barr Virus-Specific Cytotoxic T Lymphocytes + [carboplatin]+ [gemcitabine] - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 Vaccine for Epstein-Barr Viral Infections and Nasopharyngeal Cancer - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 Cell Therapy for Metastatic Nasopharyngeal Carcinoma - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Dendritic Cells + Cytokine Induced Killer Cells - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 Stem Cell Therapy for Oncology - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 abexinostat hydrochloride - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 Cell Therapy for Oncology and Infectious Disease - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 OPB-51602 - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 Cell Therapy 3 for Oncology - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 Cell Therapy 2 for Oncology and Infectious Disease - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 Cell Therapy for Nasopharingeal Carcinoma - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 Recombinant Adenoviral Human p53 Gene Therapy - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 AT-13387 - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 Small Molecules for Nasopharyngeal and Colon Cancers - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 Cell Therapy for Oncology - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 EBV-nRNA - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 RO-5203280 - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 Monoclonal Antibody Drug Conjugate to Target CD70 for Nasopharyngeal Cancer and Renal Cell Carcinoma - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 Vaccine to Target EBV for Nasopharyngeal Carcinoma - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 Nasopharyngeal Cancer - Recent Pipeline Updates 68 Nasopharyngeal Cancer - Dormant Projects 72 Nasopharyngeal Cancer - Product Development Milestones 73 Featured News & Press Releases 73 Dec 16, 2011: Radiation Therapy Oncology Group Trial Results Show Bevacizumab Reduces Spread Of Nasopharyngeal Cancer 73 May 29, 2009: Cyclacel Reports Initial Phase 2 Seliciclib Data In Patients With Nasopharyngeal Carcinoma At 2009 Asco Annual Meeting 74 Apr 21, 2009: Cyclacel & Dartmouth Researchers Reports Novel Mechanism Of Action For Seliciclib At AACR 74 Mar 05, 2009: Cyclacel Announces Phase 1 Data Elucidating Pharmacodynamics & Mechanism Of Action Of Seliciclib In Nasopharyngeal Cancer 75 Oct 07, 2008: Epstein-Barr Virus Protein Contributes to Cancer 76 Aug 28, 2008: CYCLACEL Announces Recommendations Of Data Review Committee For Seliciclib Phase 2b Non-Small Cell Lung Cancer APPRAISE Trial 76 Jun 28, 2007: Cyclacel Pharmaceuticals Announces Results Of Phase II Seliciclib Combination Studies 77 Appendix 78 Methodology 78 Coverage 78 Secondary Research 78 Primary Research 78 Expert Panel Validation 78 Contact Us 79 Disclaimer 79
List of Tables Number of Products under Development for Nasopharyngeal Cancer, H2 2014 9 Number of Products under Development for Nasopharyngeal Cancer - Comparative Analysis, H2 2014 10 Number of Products under Development by Companies, H2 2014 12 Number of Products under Investigation by Universities/Institutes, H2 2014 14 Comparative Analysis by Late Stage Development, H2 2014 15 Comparative Analysis by Clinical Stage Development, H2 2014 16 Comparative Analysis by Early Stage Development, H2 2014 17 Products under Development by Companies, H2 2014 18 Products under Investigation by Universities/Institutes, H2 2014 19 Nasopharyngeal Cancer - Pipeline by F. Hoffmann-La Roche Ltd., H2 2014 20 Nasopharyngeal Cancer - Pipeline by Gilead Sciences, Inc., H2 2014 21 Nasopharyngeal Cancer - Pipeline by Astex Pharmaceuticals, Inc., H2 2014 22 Nasopharyngeal Cancer - Pipeline by Cyclacel Pharmaceuticals, Inc., H2 2014 23 Nasopharyngeal Cancer - Pipeline by BioDiem Ltd, H2 2014 24 Nasopharyngeal Cancer - Pipeline by Pharmacyclics, Inc., H2 2014 25 Nasopharyngeal Cancer - Pipeline by Ambrx, Inc., H2 2014 26 Nasopharyngeal Cancer - Pipeline by Otsuka Holdings Co., Ltd., H2 2014 27 Nasopharyngeal Cancer - Pipeline by National Cancer Centre Singapore, H2 2014 28 Assessment by Monotherapy Products, H2 2014 29 Assessment by Combination Products, H2 2014 30 Number of Products by Stage and Target, H2 2014 33 Number of Products by Stage and Mechanism of Action, H2 2014 36 Number of Products by Stage and Route of Administration, H2 2014 38 Number of Products by Stage and Molecule Type, H2 2014 40 Nasopharyngeal Cancer Therapeutics - Recent Pipeline Updates, H2 2014 68 Nasopharyngeal Cancer - Dormant Projects, H2 2014 72
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