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Published: Jan, 2015 | Pages:
87 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Nasopharyngeal Cancer - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Nasopharyngeal Cancer - Pipeline Review, H1 2015', provides an overview of the Nasopharyngeal Cancer's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Nasopharyngeal Cancer, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Nasopharyngeal Cancer and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Nasopharyngeal Cancer - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Nasopharyngeal Cancer and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Nasopharyngeal Cancer products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Nasopharyngeal Cancer pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Nasopharyngeal Cancer - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Nasopharyngeal Cancer pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Nasopharyngeal Cancer Overview 9 Therapeutics Development 10 Pipeline Products for Nasopharyngeal Cancer - Overview 10 Pipeline Products for Nasopharyngeal Cancer - Comparative Analysis 11 Nasopharyngeal Cancer - Therapeutics under Development by Companies 12 Nasopharyngeal Cancer - Therapeutics under Investigation by Universities/Institutes 14 Nasopharyngeal Cancer - Pipeline Products Glance 16 Clinical Stage Products 16 Early Stage Products 17 Nasopharyngeal Cancer - Products under Development by Companies 18 Nasopharyngeal Cancer - Products under Investigation by Universities/Institutes 19 Nasopharyngeal Cancer - Companies Involved in Therapeutics Development 20 Ambrx, Inc. 20 AVEO Pharmaceuticals, Inc. 21 BioDiem Ltd 22 Celgene Corporation 23 Cyclacel Pharmaceuticals, Inc. 24 F. Hoffmann-La Roche Ltd. 25 GlaxoSmithKline plc 26 Merck & Co., Inc. 27 Otsuka Holdings Co., Ltd. 28 Pharmacyclics, Inc. 29 Theravectys S.A. 30 Zhejiang BetaPharma Co., Ltd. 31 Nasopharyngeal Cancer - Therapeutics Assessment 32 Assessment by Monotherapy Products 32 Assessment by Combination Products 33 Assessment by Target 34 Assessment by Mechanism of Action 36 Assessment by Route of Administration 38 Assessment by Molecule Type 40 Drug Profiles 42 abexinostat hydrochloride - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 azacitidine - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 Cell Therapy 2 for Oncology and Infectious Disease - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 Cell Therapy for Metastatic Nasopharyngeal Carcinoma and Colorectal Cancer - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Cell Therapy for Nasopharingeal Carcinoma - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 Cell Therapy to Target Latent Membrane Protein-2 for Oncology - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 Cell Therapy to Target LMP-1 and LMP-2 for Metastatic Nasopharyngeal Carcinoma - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 Cell Therapy to Target LMP-1 and LMP-2 for Oncology - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 Dendritic Cells + Cytokine Induced Killer Cells - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 EBV-nRNA - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 ficlatuzumab - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 Gene Therapy to Activate p53 for Oncology - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 GSK-2849330 - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 icotinib hydrochloride - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 MK-2206 - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 Monoclonal Antibody Drug Conjugate to Inhibit CD70 for Nasopharyngeal Cancer and Renal Cell Carcinoma - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 NEO-212 - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 OPB-51602 - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 RO-5203280 - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 seliciclib - Drug Profile 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 Small Molecules for Nasopharyngeal and Colon Cancers - Drug Profile 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 Stem Cell Therapy for Oncology - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 Vaccine for EBV Associated Nasopharyngeal Cancer - Drug Profile 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 Vaccine for Epstein-Barr Viral Infections and Nasopharyngeal Cancer - Drug Profile 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 Vaccine to Target EBV for Nasopharyngeal Carcinoma - Drug Profile 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 Nasopharyngeal Cancer - Recent Pipeline Updates 75 Nasopharyngeal Cancer - Dormant Projects 80 Nasopharyngeal Cancer - Product Development Milestones 81 Featured News & Press Releases 81 Dec 16, 2011: Radiation Therapy Oncology Group Trial Results Show Bevacizumab Reduces Spread Of Nasopharyngeal Cancer 81 May 29, 2009: Cyclacel Reports Initial Phase 2 Seliciclib Data In Patients With Nasopharyngeal Carcinoma At 2009 Asco Annual Meeting 82 Apr 21, 2009: Cyclacel & Dartmouth Researchers Reports Novel Mechanism Of Action For Seliciclib At AACR 82 Mar 05, 2009: Cyclacel Announces Phase 1 Data Elucidating Pharmacodynamics & Mechanism Of Action Of Seliciclib In Nasopharyngeal Cancer 83 Aug 28, 2008: CYCLACEL Announces Recommendations Of Data Review Committee For Seliciclib Phase 2b Non-Small Cell Lung Cancer APPRAISE Trial 84 Jun 28, 2007: Cyclacel Pharmaceuticals Announces Results Of Phase II Seliciclib Combination Studies 84 Appendix 86 Methodology 86 Coverage 86 Secondary Research 86 Primary Research 86 Expert Panel Validation 86 Contact Us 87 Disclaimer 87
List of Tables Number of Products under Development for Nasopharyngeal Cancer, H1 2015 10 Number of Products under Development for Nasopharyngeal Cancer - Comparative Analysis, H1 2015 11 Number of Products under Development by Companies, H1 2015 13 Number of Products under Investigation by Universities/Institutes, H1 2015 15 Comparative Analysis by Clinical Stage Development, H1 2015 16 Comparative Analysis by Early Stage Development, H1 2015 17 Products under Development by Companies, H1 2015 18 Products under Investigation by Universities/Institutes, H1 2015 19 Nasopharyngeal Cancer - Pipeline by Ambrx, Inc., H1 2015 20 Nasopharyngeal Cancer - Pipeline by AVEO Pharmaceuticals, Inc., H1 2015 21 Nasopharyngeal Cancer - Pipeline by BioDiem Ltd, H1 2015 22 Nasopharyngeal Cancer - Pipeline by Celgene Corporation, H1 2015 23 Nasopharyngeal Cancer - Pipeline by Cyclacel Pharmaceuticals, Inc., H1 2015 24 Nasopharyngeal Cancer - Pipeline by F. Hoffmann-La Roche Ltd., H1 2015 25 Nasopharyngeal Cancer - Pipeline by GlaxoSmithKline plc, H1 2015 26 Nasopharyngeal Cancer - Pipeline by Merck & Co., Inc., H1 2015 27 Nasopharyngeal Cancer - Pipeline by Otsuka Holdings Co., Ltd., H1 2015 28 Nasopharyngeal Cancer - Pipeline by Pharmacyclics, Inc., H1 2015 29 Nasopharyngeal Cancer - Pipeline by Theravectys S.A., H1 2015 30 Nasopharyngeal Cancer - Pipeline by Zhejiang BetaPharma Co., Ltd., H1 2015 31 Assessment by Monotherapy Products, H1 2015 32 Assessment by Combination Products, H1 2015 33 Number of Products by Stage and Target, H1 2015 35 Number of Products by Stage and Mechanism of Action, H1 2015 37 Number of Products by Stage and Route of Administration, H1 2015 39 Number of Products by Stage and Molecule Type, H1 2015 41 Nasopharyngeal Cancer Therapeutics - Recent Pipeline Updates, H1 2015 75 Nasopharyngeal Cancer - Dormant Projects, H1 2015 80
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