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Published: Dec, 2015 | Pages:
77 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Myocardial Fibrosis - Pipeline Review, H2 2015 Summary Global Markets Direct's, 'Myocardial Fibrosis - Pipeline Review, H2 2015', provides an overview of the Myocardial Fibrosis's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Myocardial Fibrosis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Myocardial Fibrosis and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Myocardial Fibrosis - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Myocardial Fibrosis and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Myocardial Fibrosis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Myocardial Fibrosis pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Myocardial Fibrosis - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Myocardial Fibrosis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents
Table of Contents 2 List of Tables 5 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Myocardial Fibrosis Overview 7 Therapeutics Development 8 Pipeline Products for Myocardial Fibrosis - Overview 8 Pipeline Products for Myocardial Fibrosis - Comparative Analysis 9 Myocardial Fibrosis - Therapeutics under Development by Companies 10 Myocardial Fibrosis - Therapeutics under Investigation by Universities/Institutes 11 Myocardial Fibrosis - Pipeline Products Glance 12 Clinical Stage Products 12 Early Stage Products 13 Myocardial Fibrosis - Products under Development by Companies 14 Myocardial Fibrosis - Products under Investigation by Universities/Institutes 15 Myocardial Fibrosis - Companies Involved in Therapeutics Development 16 AstraZeneca Plc 16 BioLineRx, Ltd. 17 Digna Biotech, S.L. 18 Evotec AG 19 Galectin Therapeutics, Inc. 20 GTx, Inc. 21 MandalMed, Inc. 22 miRagen Therapeutics, Inc. 23 ProMetic Life Sciences Inc. 24 Virocan Therapeutics Private Limited 25 Myocardial Fibrosis - Therapeutics Assessment 26 Assessment by Monotherapy Products 26 Assessment by Target 27 Assessment by Mechanism of Action 29 Assessment by Route of Administration 31 Assessment by Molecule Type 33 Drug Profiles 35 AmVicf-006 - Drug Profile 35 Product Description 35 Mechanism of Action 35 R&D Progress 35 AZ-876 - Drug Profile 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 CGEN-856 - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 disitertide - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 Drugs for Tissue Fibrosis - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 Galectin-3C - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 GM-CT-01 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 GRMD-02 - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 GTx-878 - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 MGN-4220 - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 Monoclonal Antibodies for Cardiovascular Diseases - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 P-17 - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 PBI-4050 - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 Small Molecule for Cardiac Fibrosis and Heart Failure - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 SP-20102 - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 TM-5441 - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 Myocardial Fibrosis - Recent Pipeline Updates 59 Myocardial Fibrosis - Dormant Projects 73 Myocardial Fibrosis - Product Development Milestones 74 Featured News & Press Releases 74 Oct 29, 2015: ProMetic's PBI-4050 Cleared to Commence Clinical Trial in Patients With Type 2 Diabetes and Multi-Organ Fibrosis in Europe 74 Aug 05, 2014: Galectin Therapeutics Receives U.S. Patent for GR-MD-02 Composition of Matter 74 Appendix 76 Methodology 76 Coverage 76 Secondary Research 76 Primary Research 76 Expert Panel Validation 76 Contact Us 76 Disclaimer 77
List of Tables
Number of Products under Development for Myocardial Fibrosis, H2 2015 8 Number of Products under Development for Myocardial Fibrosis - Comparative Analysis, H2 2015 9 Number of Products under Development by Companies, H2 2015 10 Number of Products under Investigation by Universities/Institutes, H2 2015 11 Comparative Analysis by Clinical Stage Development, H2 2015 12 Comparative Analysis by Early Stage Development, H2 2015 13 Products under Development by Companies, H2 2015 14 Products under Investigation by Universities/Institutes, H2 2015 15 Myocardial Fibrosis - Pipeline by AstraZeneca Plc, H2 2015 16 Myocardial Fibrosis - Pipeline by BioLineRx, Ltd., H2 2015 17 Myocardial Fibrosis - Pipeline by Digna Biotech, S.L., H2 2015 18 Myocardial Fibrosis - Pipeline by Evotec AG, H2 2015 19 Myocardial Fibrosis - Pipeline by Galectin Therapeutics, Inc., H2 2015 20 Myocardial Fibrosis - Pipeline by GTx, Inc., H2 2015 21 Myocardial Fibrosis - Pipeline by MandalMed, Inc., H2 2015 22 Myocardial Fibrosis - Pipeline by miRagen Therapeutics, Inc., H2 2015 23 Myocardial Fibrosis - Pipeline by ProMetic Life Sciences Inc., H2 2015 24 Myocardial Fibrosis - Pipeline by Virocan Therapeutics Private Limited, H2 2015 25 Assessment by Monotherapy Products, H2 2015 26 Number of Products by Stage and Target, H2 2015 28 Number of Products by Stage and Mechanism of Action, H2 2015 30 Number of Products by Stage and Route of Administration, H2 2015 32 Number of Products by Stage and Molecule Type, H2 2015 34 Myocardial Fibrosis Therapeutics - Recent Pipeline Updates, H2 2015 59 Myocardial Fibrosis - Dormant Projects, H2 2015 73
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