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Published: Oct, 2014 | Pages:
58 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Metastatic Uveal Melanoma - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Metastatic Uveal Melanoma - Pipeline Review, H2 2014', provides an overview of the Metastatic Uveal Melanoma's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Metastatic Uveal Melanoma, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Metastatic Uveal Melanoma and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Metastatic Uveal Melanoma - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Metastatic Uveal Melanoma and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Metastatic Uveal Melanoma products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Metastatic Uveal Melanoma pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Metastatic Uveal Melanoma - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Metastatic Uveal Melanoma pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Metastatic Uveal Melanoma Overview 6 Therapeutics Development 7 Pipeline Products for Metastatic Uveal Melanoma - Overview 7 Pipeline Products for Metastatic Uveal Melanoma - Comparative Analysis 8 Metastatic Uveal Melanoma - Therapeutics under Development by Companies 9 Metastatic Uveal Melanoma - Pipeline Products Glance 10 Late Stage Products 10 Clinical Stage Products 11 Metastatic Uveal Melanoma - Products under Development by Companies 12 Metastatic Uveal Melanoma - Companies Involved in Therapeutics Development 13 AstraZeneca PLC 13 Eli Lilly and Company 14 GlaxoSmithKline plc 15 Novartis AG 16 Spectrum Pharmaceuticals, Inc. 17 Metastatic Uveal Melanoma - Therapeutics Assessment 18 Assessment by Monotherapy Products 18 Assessment by Combination Products 19 Assessment by Target 20 Assessment by Mechanism of Action 22 Assessment by Route of Administration 24 Assessment by Molecule Type 26 Drug Profiles 28 selumetinib sulfate - Drug Profile 28 Product Description 28 Mechanism of Action 28 R&D Progress 28 vincristine sulfate - Drug Profile 31 Product Description 31 Mechanism of Action 31 R&D Progress 31 trametinib dimethyl sulfoxide + uprosertib - Drug Profile 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 LY-2801653 - Drug Profile 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 sotrastaurin acetate - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 binimetinib - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 emibetuzumab - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 Metastatic Uveal Melanoma - Recent Pipeline Updates 44 Metastatic Uveal Melanoma - Dormant Projects 54 Metastatic Uveal Melanoma - Product Development Milestones 55 Featured News & Press Releases 55 Jun 01, 2013: AstraZeneca's New Therapy Selumetinib Improves Progression-Free Survival And Shrink Tumors In Metastatic Uveal Melanoma, Researchers Report 55 May 07, 2013: Exelixis To Feature Nine Presentations On Cabozantinib At 2013 ASCO Annual Meeting 55 Appendix 57 Methodology 57 Coverage 57 Secondary Research 57 Primary Research 57 Expert Panel Validation 57 Contact Us 58 Disclaimer 58
List of Tables Number of Products under Development for Metastatic Uveal Melanoma, H2 2014 7 Number of Products under Development for Metastatic Uveal Melanoma - Comparative Analysis, H2 2014 8 Number of Products under Development by Companies, H2 2014 9 Comparative Analysis by Late Stage Development, H2 2014 10 Comparative Analysis by Clinical Stage Development, H2 2014 11 Products under Development by Companies, H2 2014 12 Metastatic Uveal Melanoma - Pipeline by AstraZeneca PLC, H2 2014 13 Metastatic Uveal Melanoma - Pipeline by Eli Lilly and Company, H2 2014 14 Metastatic Uveal Melanoma - Pipeline by GlaxoSmithKline plc, H2 2014 15 Metastatic Uveal Melanoma - Pipeline by Novartis AG, H2 2014 16 Metastatic Uveal Melanoma - Pipeline by Spectrum Pharmaceuticals, Inc., H2 2014 17 Assessment by Monotherapy Products, H2 2014 18 Assessment by Combination Products, H2 2014 19 Number of Products by Stage and Target, H2 2014 21 Number of Products by Stage and Mechanism of Action, H2 2014 23 Number of Products by Stage and Route of Administration, H2 2014 25 Number of Products by Stage and Molecule Type, H2 2014 27 Metastatic Uveal Melanoma Therapeutics - Recent Pipeline Updates, H2 2014 44 Metastatic Uveal Melanoma - Dormant Projects, H2 2014 54
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