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Published: Sep, 2014 | Pages:
79 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Metastatic Ovarian Cancer - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Metastatic Ovarian Cancer - Pipeline Review, H2 2014', provides an overview of the Metastatic Ovarian Cancer's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Metastatic Ovarian Cancer, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Metastatic Ovarian Cancer and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Metastatic Ovarian Cancer - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Metastatic Ovarian Cancer and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Metastatic Ovarian Cancer products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Metastatic Ovarian Cancer pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Metastatic Ovarian Cancer - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Metastatic Ovarian Cancer pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Metastatic Ovarian Cancer Overview 7 Therapeutics Development 8 Pipeline Products for Metastatic Ovarian Cancer - Overview 8 Pipeline Products for Metastatic Ovarian Cancer - Comparative Analysis 9 Metastatic Ovarian Cancer - Therapeutics under Development by Companies 10 Metastatic Ovarian Cancer - Therapeutics under Investigation by Universities/Institutes 12 Metastatic Ovarian Cancer - Pipeline Products Glance 13 Late Stage Products 13 Clinical Stage Products 14 Early Stage Products 15 Metastatic Ovarian Cancer - Products under Development by Companies 16 Metastatic Ovarian Cancer - Products under Investigation by Universities/Institutes 17 Metastatic Ovarian Cancer - Companies Involved in Therapeutics Development 18 F. Hoffmann-La Roche Ltd. 18 Sumitomo Dainippon Pharma Co., Ltd. 19 Millennium Pharmaceuticals, Inc. 20 Eisai Co., Ltd. 21 Northwest Biotherapeutics, Inc. 22 VG Life Sciences, Inc. 23 Immune Design Corp. 24 Aura Biosciences, Inc. 25 Metastatic Ovarian Cancer - Therapeutics Assessment 26 Assessment by Monotherapy Products 26 Assessment by Combination Products 27 Assessment by Target 28 Assessment by Mechanism of Action 31 Assessment by Route of Administration 34 Assessment by Molecule Type 36 Drug Profiles 38 bevacizumab - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 orteronel - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 antigen-presenting dendritic cells (living, autologous) - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 E-7449 - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 DCVax-Direct - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Stem Cell Therapy for Oncology - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 hydroxychloroquine + sorafenib tosylate - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 LV-305 - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 G-305 - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 Drugs for Metastatic Ovarian Cancer - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 SM-276001 - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 Drugs for Cancer - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 Metastatic Ovarian Cancer - Recent Pipeline Updates 57 Metastatic Ovarian Cancer - Dormant Projects 71 Metastatic Ovarian Cancer - Discontinued Products 72 Metastatic Ovarian Cancer - Product Development Milestones 73 Featured News & Press Releases 73 Mar 10, 2014: NW Bio Announces Two German Approvals: "Hospital Exemption" for Early Access Program with DCVax-L and Eligibility of DCVax-L for Reimbursement 73 Jan 09, 2014: Synta Announces Launch of GANNET53, a Randomized, pan-European Study of Ganetespib in p53 Mutant, Metastatic Ovarian Cancer 74 Mar 18, 2013: Merrimack Pharma Completes Enrollment In Phase II Study Of MM-121 In Combination With Paclitaxel In Patients With Platinum-resistant Or Refractory Advanced Ovarian Cancers 75 Mar 06, 2013: Ziopharm Oncology Announces Initiation Of Indiana University-sponsored Phase II Study Of Palifosfamide In Recurrent And Incurable Germ Cell Tumors 76 Oct 02, 2012: Merrimack Pharma Presents Phase I Study Of MM-121 At European Society For Medical Oncology 2012 76 Appendix 78 Methodology 78 Coverage 78 Secondary Research 78 Primary Research 78 Expert Panel Validation 78 Contact Us 79 Disclaimer 79
List of Tables Number of Products under Development for Metastatic Ovarian Cancer, H2 2014 8 Number of Products under Development for Metastatic Ovarian Cancer - Comparative Analysis, H2 2014 9 Number of Products under Development by Companies, H2 2014 11 Number of Products under Investigation by Universities/Institutes, H2 2014 12 Comparative Analysis by Late Stage Development, H2 2014 13 Comparative Analysis by Clinical Stage Development, H2 2014 14 Comparative Analysis by Early Stage Development, H2 2014 15 Products under Development by Companies, H2 2014 16 Products under Investigation by Universities/Institutes, H2 2014 17 Metastatic Ovarian Cancer - Pipeline by F. Hoffmann-La Roche Ltd., H2 2014 18 Metastatic Ovarian Cancer - Pipeline by Sumitomo Dainippon Pharma Co., Ltd., H2 2014 19 Metastatic Ovarian Cancer - Pipeline by Millennium Pharmaceuticals, Inc., H2 2014 20 Metastatic Ovarian Cancer - Pipeline by Eisai Co., Ltd., H2 2014 21 Metastatic Ovarian Cancer - Pipeline by Northwest Biotherapeutics, Inc., H2 2014 22 Metastatic Ovarian Cancer - Pipeline by VG Life Sciences, Inc., H2 2014 23 Metastatic Ovarian Cancer - Pipeline by Immune Design Corp., H2 2014 24 Metastatic Ovarian Cancer - Pipeline by Aura Biosciences, Inc., H2 2014 25 Assessment by Monotherapy Products, H2 2014 26 Assessment by Combination Products, H2 2014 27 Number of Products by Stage and Target, H2 2014 30 Number of Products by Stage and Mechanism of Action, H2 2014 33 Number of Products by Stage and Route of Administration, H2 2014 35 Number of Products by Stage and Molecule Type, H2 2014 37 Metastatic Ovarian Cancer Therapeutics - Recent Pipeline Updates, H2 2014 57 Metastatic Ovarian Cancer - Dormant Projects, H2 2014 71 Metastatic Ovarian Cancer - Discontinued Products, H2 2014 72
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