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Published: Jan, 2015 | Pages:
145 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Metastatic Adenocarcinoma of The Pancreas - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Metastatic Adenocarcinoma of The Pancreas - Pipeline Review, H1 2015', provides an overview of the Metastatic Adenocarcinoma of The Pancreas's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Metastatic Adenocarcinoma of The Pancreas, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Metastatic Adenocarcinoma of The Pancreas and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Metastatic Adenocarcinoma of The Pancreas - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Metastatic Adenocarcinoma of The Pancreas and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Metastatic Adenocarcinoma of The Pancreas products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Metastatic Adenocarcinoma of The Pancreas pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons To Buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Metastatic Adenocarcinoma of The Pancreas - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Metastatic Adenocarcinoma of The Pancreas pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Metastatic Adenocarcinoma of The Pancreas Overview 9 Therapeutics Development 10 Pipeline Products for Metastatic Adenocarcinoma of The Pancreas - Overview 10 Pipeline Products for Metastatic Adenocarcinoma of The Pancreas - Comparative Analysis 11 Metastatic Adenocarcinoma of The Pancreas - Therapeutics under Development by Companies 12 Metastatic Adenocarcinoma of The Pancreas - Therapeutics under Investigation by Universities/Institutes 15 Metastatic Adenocarcinoma of The Pancreas - Pipeline Products Glance 16 Late Stage Products 16 Clinical Stage Products 17 Metastatic Adenocarcinoma of The Pancreas - Products under Development by Companies 18 Metastatic Adenocarcinoma of The Pancreas - Products under Investigation by Universities/Institutes 20 Metastatic Adenocarcinoma of The Pancreas - Companies Involved in Therapeutics Development 21 Aduro BioTech, Inc. 21 Amgen Inc. 22 Axcentua Pharmaceuticals AB 23 BioCancell Therapeutics, Inc. 24 Boehringer Ingelheim GmbH 25 Boston Biomedical, Inc. 26 Eleison Pharmaceuticals, Inc. 27 Gilead Sciences, Inc. 28 Halozyme Therapeutics, Inc. 29 Incyte Corporation 30 Millennium Pharmaceuticals, Inc. 31 Nanotherapeutics, Inc. 32 NewLink Genetics Corporation 33 Novartis AG 34 Phoenix Biotechnology, Inc. 35 Sanofi 36 Teva Pharmaceutical Industries Limited 37 Threshold Pharmaceuticals, Inc. 38 Metastatic Adenocarcinoma of The Pancreas - Therapeutics Assessment 39 Assessment by Monotherapy Products 39 Assessment by Target 40 Assessment by Mechanism of Action 42 Assessment by Route of Administration 44 Assessment by Molecule Type 46 Drug Profiles 48 AXP-10711 - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 BBI-608 - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 BC-819 - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 BI-853520 - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 binimetinib - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 CEP-37250 - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 CRS-207 - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 Dendritic Cell Therapy for Cancer - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 erismodegib - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 evofosfamide - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 ganitumab - Drug Profile 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 glufosfamide - Drug Profile 76 Product Description 76 Mechanism of Action 76 R&D Progress 76 indoximod - Drug Profile 78 Product Description 78 Mechanism of Action 78 R&D Progress 78 LGK-974 - Drug Profile 80 Product Description 80 Mechanism of Action 80 R&D Progress 80 MesoCART - Drug Profile 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 MLN-0264 - Drug Profile 82 Product Description 82 Mechanism of Action 82 R&D Progress 82 paclitaxel lipsomal - Drug Profile 83 Product Description 83 Mechanism of Action 83 R&D Progress 83 PBI-05204 - Drug Profile 85 Product Description 85 Mechanism of Action 85 R&D Progress 85 PEGPH-20 - Drug Profile 87 Product Description 87 Mechanism of Action 87 R&D Progress 87 plerixafor - Drug Profile 89 Product Description 89 Mechanism of Action 89 R&D Progress 89 PRI-724 - Drug Profile 91 Product Description 91 Mechanism of Action 91 R&D Progress 91 ruxolitinib phosphate - Drug Profile 93 Product Description 93 Mechanism of Action 93 R&D Progress 93 SiG12D-LODER - Drug Profile 98 Product Description 98 Mechanism of Action 98 R&D Progress 98 simtuzumab - Drug Profile 100 Product Description 100 Mechanism of Action 100 R&D Progress 100 Stem Cell Therapy for Oncology - Drug Profile 102 Product Description 102 Mechanism of Action 102 R&D Progress 102 Triapine - Drug Profile 103 Product Description 103 Mechanism of Action 103 R&D Progress 103 Metastatic Adenocarcinoma of The Pancreas - Recent Pipeline Updates 105 Metastatic Adenocarcinoma of The Pancreas - Dormant Projects 141 Metastatic Adenocarcinoma of The Pancreas - Discontinued Products 142 Metastatic Adenocarcinoma of The Pancreas - Product Development Milestones 143 Featured News & Press Releases 143 Nov 03, 2014: Threshold Pharmaceuticals' Partner Merck KGaA Completes Target Enrollment in the TH-302 Phase 3 MAESTRO Study in Patients With Locally Advanced or Metastatic Pancreatic Adenocarcinoma 143 Appendix 144 Methodology 144 Coverage 144 Secondary Research 144 Primary Research 144 Expert Panel Validation 144 Contact Us 144 Disclaimer 145
List of Tables Number of Products under Development for Metastatic Adenocarcinoma of The Pancreas, H1 2015 10 Number of Products under Development for Metastatic Adenocarcinoma of The Pancreas - Comparative Analysis, H1 2015 11 Number of Products under Development by Companies, H1 2015 13 Number of Products under Development by Companies, H1 2015 (Contd..1) 14 Number of Products under Investigation by Universities/Institutes, H1 2015 15 Comparative Analysis by Late Stage Development, H1 2015 16 Comparative Analysis by Clinical Stage Development, H1 2015 17 Products under Development by Companies, H1 2015 18 Products under Development by Companies, H1 2015 (Contd..1) 19 Products under Investigation by Universities/Institutes, H1 2015 20 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Aduro BioTech, Inc., H1 2015 21 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Amgen Inc., H1 2015 22 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Axcentua Pharmaceuticals AB, H1 2015 23 Metastatic Adenocarcinoma of The Pancreas - Pipeline by BioCancell Therapeutics, Inc., H1 2015 24 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Boehringer Ingelheim GmbH, H1 2015 25 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Boston Biomedical, Inc., H1 2015 26 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Eleison Pharmaceuticals, Inc., H1 2015 27 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Gilead Sciences, Inc., H1 2015 28 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Halozyme Therapeutics, Inc., H1 2015 29 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Incyte Corporation, H1 2015 30 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Millennium Pharmaceuticals, Inc., H1 2015 31 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Nanotherapeutics, Inc., H1 2015 32 Metastatic Adenocarcinoma of The Pancreas - Pipeline by NewLink Genetics Corporation, H1 2015 33 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Novartis AG, H1 2015 34 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Phoenix Biotechnology, Inc., H1 2015 35 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Sanofi, H1 2015 36 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Teva Pharmaceutical Industries Limited, H1 2015 37 Metastatic Adenocarcinoma of The Pancreas - Pipeline by Threshold Pharmaceuticals, Inc., H1 2015 38 Assessment by Monotherapy Products, H1 2015 39 Number of Products by Stage and Target, H1 2015 41 Number of Products by Stage and Mechanism of Action, H1 2015 43 Number of Products by Stage and Route of Administration, H1 2015 45 Number of Products by Stage and Molecule Type, H1 2015 47 Metastatic Adenocarcinoma of The Pancreas Therapeutics - Recent Pipeline Updates, H1 2015 105 Metastatic Adenocarcinoma of The Pancreas - Dormant Projects, H1 2015 141 Metastatic Adenocarcinoma of The Pancreas - Discontinued Products, H1 2015 142
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