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Published: Dec, 2016 | Pages:
157 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Merkel Cell Carcinoma - Pipeline Review, H2 2016 Summary Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Merkel Cell Carcinoma - Pipeline Review, H2 2016, provides an overview of the Merkel Cell Carcinoma (Oncology) pipeline landscape. Merkel cell carcinoma is a rare aggressive skin cancer that is at high risk of recurring and spreading (metastasizing) throughout the body. Risk factors for Merkel cell carcinoma include age, gender, light skin color, Ultraviolet exposure and immune suppression. Symptom includes painless nodule on skin. It usually starts on areas of skin exposed to the sun (face, neck, arms, and legs). Treatment includes chemotherapy, radiation therapy and surgery. Report Highlights Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Merkel Cell Carcinoma - Pipeline Review, H2 2016, provides comprehensive information on the therapeutics under development for Merkel Cell Carcinoma (Oncology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. The Merkel Cell Carcinoma (Oncology) pipeline guide also reviews of key players involved in therapeutic development for Merkel Cell Carcinoma and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Phase II, Phase I and Preclinical stages are 1, 7, 5 and 1 respectively. Similarly, the Universities portfolio in Phase I stages comprises 1 molecules, respectively. Merkel Cell Carcinoma (Oncology) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data. Scope - The pipeline guide provides a snapshot of the global therapeutic landscape of Merkel Cell Carcinoma (Oncology). - The pipeline guide reviews pipeline therapeutics for Merkel Cell Carcinoma (Oncology) by companies and universities/research institutes based on information derived from company and industry-specific sources. - The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages. - The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities. - The pipeline guide reviews key companies involved in Merkel Cell Carcinoma (Oncology) therapeutics and enlists all their major and minor projects. - The pipeline guide evaluates Merkel Cell Carcinoma (Oncology) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. - The pipeline guide encapsulates all the dormant and discontinued pipeline projects. - The pipeline guide reviews latest news related to pipeline therapeutics for Merkel Cell Carcinoma (Oncology) Reasons To Buy - Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies. - Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage. - Find and recognize significant and varied types of therapeutics under development for Merkel Cell Carcinoma (Oncology). - Classify potential new clients or partners in the target demographic. - Develop tactical initiatives by understanding the focus areas of leading companies. - Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics. - Formulate corrective measures for pipeline projects by understanding Merkel Cell Carcinoma (Oncology) pipeline depth and focus of Indication therapeutics. - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope. - Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
Table of Contents
Table of Contents 2 List of Tables 5 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Merkel Cell Carcinoma Overview 7 Pipeline Products for Merkel Cell Carcinoma - Overview 8 Pipeline Products for Merkel Cell Carcinoma - Comparative Analysis 9 Merkel Cell Carcinoma - Therapeutics under Development by Companies 10 Merkel Cell Carcinoma - Therapeutics under Investigation by Universities/Institutes 11 Merkel Cell Carcinoma - Pipeline Products Glance 12 Late Stage Products 12 Clinical Stage Products 13 Early Stage Products 14 Merkel Cell Carcinoma - Products under Development by Companies 15 Merkel Cell Carcinoma - Products under Investigation by Universities/Institutes 16 Merkel Cell Carcinoma - Companies Involved in Therapeutics Development 17 Amgen Inc 17 Apcure SAS 18 BeiGene Ltd 19 Immune Design Corp 20 Merck & Co Inc 21 Merck KGaA 22 Millennium Pharmaceuticals Inc 23 NantKwest Inc 24 Novartis AG 25 OncoSec Medical Inc 26 Oncovir Inc 27 Ono Pharmaceutical Co Ltd 28 Merkel Cell Carcinoma - Therapeutics Assessment 29 Assessment by Monotherapy Products 29 Assessment by Target 30 Assessment by Mechanism of Action 32 Assessment by Route of Administration 34 Assessment by Molecule Type 36 Drug Profiles 38 aNK Program - Drug Profile 38 Product Description 38 Mechanism Of Action 38 R&D Progress 38 APC-001 - Drug Profile 41 Product Description 41 Mechanism Of Action 41 R&D Progress 41 avelumab - Drug Profile 42 Product Description 42 Mechanism Of Action 42 R&D Progress 42 BGBA-317 - Drug Profile 48 Product Description 48 Mechanism Of Action 48 R&D Progress 48 DNA IL-12 - Drug Profile 50 Product Description 50 Mechanism Of Action 50 R&D Progress 50 EBC-46 - Drug Profile 58 Product Description 58 Mechanism Of Action 58 R&D Progress 58 G-100 - Drug Profile 60 Product Description 60 Mechanism Of Action 60 R&D Progress 60 nivolumab - Drug Profile 63 Product Description 63 Mechanism Of Action 63 R&D Progress 63 pasireotide - Drug Profile 91 Product Description 91 Mechanism Of Action 91 R&D Progress 91 pazopanib hydrochloride - Drug Profile 95 Product Description 95 Mechanism Of Action 95 R&D Progress 95 pembrolizumab - Drug Profile 102 Product Description 102 Mechanism Of Action 102 R&D Progress 102 Poly-ICLC - Drug Profile 139 Product Description 139 Mechanism Of Action 139 R&D Progress 139 sapanisertib - Drug Profile 142 Product Description 142 Mechanism Of Action 142 R&D Progress 142 talimogene laherparepvec - Drug Profile 145 Product Description 145 Mechanism Of Action 145 R&D Progress 145 Vaccine to Target WT1 for Oncology - Drug Profile 151 Product Description 151 Mechanism Of Action 151 R&D Progress 151 Merkel Cell Carcinoma - Product Development Milestones 152 Featured News & Press Releases 152 Nov 29, 2016: FDA Accepts the Biologics License Application for Avelumab for the Treatment of Metastatic Merkel Cell Carcinoma for Priority Review 152 Nov 14, 2016: NantKwest Announces Achievement of End Point in Merkel Cell Carcinoma Phase II Trial With Evidence of Efficacy of Activated Natural Killer (aNK) Cells in Solid Tumors 153 Oct 31, 2016: European Medicines Agency Validates the Marketing Authorization Application for Avelumab for the Treatment of Metastatic Merkel Cell Carcinoma 153 Sep 28, 2016: Merck to Present Data on Avelumab at ESMO 2016 154 Appendix 156 Methodology 156 Coverage 156 Secondary Research 156 Primary Research 156 Expert Panel Validation 156 Contact Us 156 Disclaimer 157
List of Tables
Number of Products under Development for Merkel Cell Carcinoma, H2 2016 8 Number of Products under Development for Merkel Cell Carcinoma - Comparative Analysis, H2 2016 9 Number of Products under Development by Companies, H2 2016 10 Number of Products under Investigation by Universities/Institutes, H2 2016 11 Comparative Analysis by Late Stage Development, H2 2016 12 Comparative Analysis by Clinical Stage Development, H2 2016 13 Comparative Analysis by Early Stage Development, H2 2016 14 Products under Development by Companies, H2 2016 15 Products under Investigation by Universities/Institutes, H2 2016 16 Merkel Cell Carcinoma - Pipeline by Amgen Inc, H2 2016 17 Merkel Cell Carcinoma - Pipeline by Apcure SAS, H2 2016 18 Merkel Cell Carcinoma - Pipeline by BeiGene Ltd, H2 2016 19 Merkel Cell Carcinoma - Pipeline by Immune Design Corp, H2 2016 20 Merkel Cell Carcinoma - Pipeline by Merck & Co Inc, H2 2016 21 Merkel Cell Carcinoma - Pipeline by Merck KGaA, H2 2016 22 Merkel Cell Carcinoma - Pipeline by Millennium Pharmaceuticals Inc, H2 2016 23 Merkel Cell Carcinoma - Pipeline by NantKwest Inc, H2 2016 24 Merkel Cell Carcinoma - Pipeline by Novartis AG, H2 2016 25 Merkel Cell Carcinoma - Pipeline by OncoSec Medical Inc, H2 2016 26 Merkel Cell Carcinoma - Pipeline by Oncovir Inc, H2 2016 27 Merkel Cell Carcinoma - Pipeline by Ono Pharmaceutical Co Ltd, H2 2016 28 Assessment by Monotherapy Products, H2 2016 29 Number of Products by Stage and Target, H2 2016 31 Number of Products by Stage and Mechanism of Action, H2 2016 33 Number of Products by Stage and Route of Administration, H2 2016 35 Number of Products by Stage and Molecule Type, H2 2016 37
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