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Published: Aug, 2016 | Pages:
86 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Liver Cirrhosis - Pipeline Review, H2 2016 Summary Global Markets Direct's, 'Liver Cirrhosis - Pipeline Review, H2 2016', provides an overview of the Liver Cirrhosis pipeline landscape. The report provides comprehensive information on the therapeutics under development for Liver Cirrhosis, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Liver Cirrhosis and features dormant and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data. Scope - The report provides a snapshot of the global therapeutic landscape of Liver Cirrhosis - The report reviews pipeline therapeutics for Liver Cirrhosis by companies and universities/research institutes based on information derived from company and industry-specific sources - The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages - The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved Liver Cirrhosis therapeutics and enlists all their major and minor projects - The report assesses Liver Cirrhosis therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type - The report summarizes all the dormant and discontinued pipeline projects - The report reviews latest news related to pipeline therapeutics for Liver Cirrhosis Reasons To Buy - Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Identify and understand important and diverse types of therapeutics under development for Liver Cirrhosis - Identify potential new clients or partners in the target demographic - Develop strategic initiatives by understanding the focus areas of leading companies - Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics - Devise corrective measures for pipeline projects by understanding Liver Cirrhosis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents
Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Liver Cirrhosis Overview 8 Therapeutics Development 9 Pipeline Products for Liver Cirrhosis - Overview 9 Pipeline Products for Liver Cirrhosis - Comparative Analysis 10 Liver Cirrhosis - Therapeutics under Development by Companies 11 Liver Cirrhosis - Therapeutics under Investigation by Universities/Institutes 12 Liver Cirrhosis - Pipeline Products Glance 13 Late Stage Products 13 Clinical Stage Products 14 Early Stage Products 15 Liver Cirrhosis - Products under Development by Companies 16 Liver Cirrhosis - Products under Investigation by Universities/Institutes 17 Liver Cirrhosis - Companies Involved in Therapeutics Development 18 Conatus Pharmaceuticals Inc. 18 Digna Biotech, S.L. 19 Galectin Therapeutics, Inc. 20 Human Stem Cells Institute 21 Nimbus Therapeutics, LLC 22 Ocera Therapeutics, Inc. 23 Pharmicell Co., Ltd. 24 S-Evans Biosciences, Inc. 25 Stelic Institute & Co., Inc. 26 Liver Cirrhosis - Therapeutics Assessment 27 Assessment by Monotherapy Products 27 Assessment by Target 28 Assessment by Mechanism of Action 30 Assessment by Route of Administration 32 Assessment by Molecule Type 34 Drug Profiles 36 Cellgram-LC - Drug Profile 36 Product Description 36 Mechanism Of Action 36 R&D Progress 36 DB-027 - Drug Profile 37 Product Description 37 Mechanism Of Action 37 R&D Progress 37 DB-036 - Drug Profile 38 Product Description 38 Mechanism Of Action 38 R&D Progress 38 emricasan - Drug Profile 39 Product Description 39 Mechanism Of Action 39 R&D Progress 39 Gemacell - Drug Profile 45 Product Description 45 Mechanism Of Action 45 R&D Progress 45 GRMD-02 - Drug Profile 46 Product Description 46 Mechanism Of Action 46 R&D Progress 46 GXHPC-1 - Drug Profile 57 Product Description 57 Mechanism Of Action 57 R&D Progress 57 ND-654 - Drug Profile 58 Product Description 58 Mechanism Of Action 58 R&D Progress 58 ornithine phenylacetate - Drug Profile 60 Product Description 60 Mechanism Of Action 60 R&D Progress 60 Small Molecules to Inhibit NLRP3 for Liver Cirrhosis and Non-Alcoholic Steatohepatitis - Drug Profile 65 Product Description 65 Mechanism Of Action 65 R&D Progress 65 Stem Cell Therapy for Articular Cartilage Defect, Cerebral Hemorrhage, Liver Cirrhosis and Pneumoconiosis - Drug Profile 66 Product Description 66 Mechanism Of Action 66 R&D Progress 66 Stem Cell Therapy for Liver Cirrhosis and Rheumatoid Arthritis - Drug Profile 67 Product Description 67 Mechanism Of Action 67 R&D Progress 67 Stem Cell Therapy for Liver Fibrosis and Liver Cirrhosis - Drug Profile 68 Product Description 68 Mechanism Of Action 68 R&D Progress 68 Stem Cell Therapy for Metabolic, Gastrointestinal, Multiple Organ Failure and Respiratory Disorders - Drug Profile 69 Product Description 69 Mechanism Of Action 69 R&D Progress 69 STNM-04 - Drug Profile 70 Product Description 70 Mechanism Of Action 70 R&D Progress 70 Liver Cirrhosis - Dormant Projects 71 Liver Cirrhosis - Discontinued Products 72 Liver Cirrhosis - Product Development Milestones 73 Featured News & Press Releases 73 May 04, 2016: Conatus Extends Positive Results with Emricasan in Phase 2 Liver Cirrhosis Clinical Trial 73 Apr 18, 2016: Conatus Late Breaker Oral Presentation at EASL Details Phase 2 Liver Cirrhosis Trial Three-month Data 74 Mar 30, 2016: Conatus Pharmaceuticals Announces Late Breaker Oral Presentation on Emricasan at EASL Meeting 75 Jan 05, 2016: Conatus Achieves Positive Results with Emricasan in Initial Stage of Phase 2 Liver Cirrhosis Clinical Trial 76 Nov 16, 2015: Conatus Pharmaceuticals Announces Late-Breaking Oral Presentation at AASLD Annual Meeting 77 Nov 16, 2015: Conatus Pharmaceuticals Announces Poster Presentations at AASLD Annual Meeting 78 Oct 20, 2015: Conatus Pharmaceuticals Announces Acceptance of Late-Breaking Abstract for AASLD Annual Meeting 78 Oct 01, 2015: Conatus Pharmaceuticals Announces Acceptance of Abstracts for AASLD Annual Meeting 79 Jun 25, 2015: Conatus Announces Initial Baseline Data From Phase 2b POLT-HCV-SVR Clinical Trial of Emricasan Confirming Activity of Relevant Mechanisms and Opportunity for Histological Improvement 79 May 14, 2015: Galectin Therapeutics Reports no Drug-Drug Interaction Between GR-MD-02 and Midazolam 81 Nov 10, 2014: Conatus Pharmaceuticals Presents Late-Breaking Poster At AASLD Annual Meeting 82 Oct 08, 2014: Conatus Pharmaceuticals Announces Acceptance Of Late-Breaking Abstract For AASLD Annual Meeting 83 Sep 02, 2014: Conatus Pharmaceuticals Initiates Phase 2 Trial in Patients with Liver Cirrhosis and Separate Open Label Phase 2 Trial in Cirrhosis Patients with Portal Hypertension 83 Jul 23, 2012: Galectin Therapeutics Receives US Patent for Potential Treatment for Chronic Liver Disease with Fibrosis And Cirrhosis 84 Appendix 85 Methodology 85 Coverage 85 Secondary Research 85 Primary Research 85 Expert Panel Validation 85 Contact Us 85 Disclaimer 86
List of Tables
Number of Products under Development for Liver Cirrhosis, H2 2016 9 Number of Products under Development for Liver Cirrhosis - Comparative Analysis, H2 2016 10 Number of Products under Development by Companies, H2 2016 11 Number of Products under Investigation by Universities/Institutes, H2 2016 12 Comparative Analysis by Late Stage Development, H2 2016 13 Comparative Analysis by Clinical Stage Development, H2 2016 14 Comparative Analysis by Early Stage Development, H2 2016 15 Products under Development by Companies, H2 2016 16 Products under Investigation by Universities/Institutes, H2 2016 17 Liver Cirrhosis - Pipeline by Conatus Pharmaceuticals Inc., H2 2016 18 Liver Cirrhosis - Pipeline by Digna Biotech, S.L., H2 2016 19 Liver Cirrhosis - Pipeline by Galectin Therapeutics, Inc., H2 2016 20 Liver Cirrhosis - Pipeline by Human Stem Cells Institute, H2 2016 21 Liver Cirrhosis - Pipeline by Nimbus Therapeutics, LLC, H2 2016 22 Liver Cirrhosis - Pipeline by Ocera Therapeutics, Inc., H2 2016 23 Liver Cirrhosis - Pipeline by Pharmicell Co., Ltd., H2 2016 24 Liver Cirrhosis - Pipeline by S-Evans Biosciences, Inc., H2 2016 25 Liver Cirrhosis - Pipeline by Stelic Institute & Co., Inc., H2 2016 26 Assessment by Monotherapy Products, H2 2016 27 Number of Products by Stage and Target, H2 2016 29 Number of Products by Stage and Mechanism of Action, H2 2016 31 Number of Products by Stage and Route of Administration, H2 2016 33 Number of Products by Stage and Molecule Type, H2 2016 35 Liver Cirrhosis - Dormant Projects, H2 2016 71 Liver Cirrhosis - Discontinued Products, H2 2016 72
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