Toll Free: 1-888-928-9744
Published: Sep, 2014 | Pages:
146 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Irritable Bowel Syndrome - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Irritable Bowel Syndrome - Pipeline Review, H2 2014', provides an overview of the Irritable Bowel Syndrome's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Irritable Bowel Syndrome, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Irritable Bowel Syndrome and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Irritable Bowel Syndrome - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Irritable Bowel Syndrome and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Irritable Bowel Syndrome products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Irritable Bowel Syndrome pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Irritable Bowel Syndrome - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Irritable Bowel Syndrome pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 7 List of Figures 8 Introduction 9 Global Markets Direct Report Coverage 9 Irritable Bowel Syndrome Overview 10 Therapeutics Development 11 Pipeline Products for Irritable Bowel Syndrome - Overview 11 Pipeline Products for Irritable Bowel Syndrome - Comparative Analysis 12 Irritable Bowel Syndrome - Therapeutics under Development by Companies 13 Irritable Bowel Syndrome - Pipeline Products Glance 16 Late Stage Products 16 Clinical Stage Products 17 Early Stage Products 18 Irritable Bowel Syndrome - Products under Development by Companies 19 Irritable Bowel Syndrome - Companies Involved in Therapeutics Development 20 AstraZeneca PLC 20 Sumitomo Dainippon Pharma Co., Ltd. 21 Takeda Pharmaceutical Company Limited 22 Astellas Pharma Inc. 23 Ono Pharmaceutical Co., Ltd. 24 SK Chemicals Co., Ltd. 25 Teva Pharmaceutical Industries Limited 26 A. Menarini Industrie Farmaceutiche Riunite Srl 27 AlbireoPharma 28 Lexicon Pharmaceuticals, Inc. 29 Yuhan Corporation 30 Alba Therapeutics Corporation 31 Ironwood Pharmaceuticals, Inc. 32 Rottapharm SpA 33 Tioga Pharmaceuticals, Inc. 34 Synthetic Biologics, Inc. 35 Drais Pharmaceuticals, Inc. 36 Synergy Pharmaceuticals, Inc. 37 Protagonist Therapeutics Inc. 38 Alfa Wassermann S.p.A 39 RaQualia Pharma Inc. 40 Furiex Pharmaceuticals, Inc. 41 Hanmi Pharmaceuticals, Co. Ltd. 42 X-BODY BioSciences, Inc. 43 ImmusanT, Inc. 44 AltheRx Pharmaceuticals, Inc. 45 GIcare Pharma Inc 46 Dong-A Socio Group 47 Irritable Bowel Syndrome - Therapeutics Assessment 48 Assessment by Monotherapy Products 48 Assessment by Combination Products 49 Assessment by Target 50 Assessment by Mechanism of Action 53 Assessment by Route of Administration 57 Assessment by Molecule Type 59 Drug Profiles 61 rifaximin - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 eluxadoline - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 ibodutant - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 linaclotide - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 asimadoline - Drug Profile 69 Product Description 69 Mechanism of Action 69 R&D Progress 69 dexloxiglumide - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 rifaximin - Drug Profile 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 tenapanor hydrochloride - Drug Profile 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 plecanatide - Drug Profile 76 Product Description 76 Mechanism of Action 76 R&D Progress 76 solabegron hydrochloride - Drug Profile 77 Product Description 77 Mechanism of Action 77 R&D Progress 77 elobixibat - Drug Profile 79 Product Description 79 Mechanism of Action 79 R&D Progress 79 ONO-2952 - Drug Profile 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 LX-1033 - Drug Profile 83 Product Description 83 Mechanism of Action 83 R&D Progress 83 ASP-7147 - Drug Profile 85 Product Description 85 Mechanism of Action 85 R&D Progress 85 (Bacillus subtilis + mosapride + Streptococcus faecium) - Drug Profile 86 Product Description 86 Mechanism of Action 86 R&D Progress 86 DSP-6952 - Drug Profile 87 Product Description 87 Mechanism of Action 87 R&D Progress 87 SKI-3246 - Drug Profile 88 Product Description 88 Mechanism of Action 88 R&D Progress 88 SYN-010 - Drug Profile 89 Product Description 89 Mechanism of Action 89 R&D Progress 89 larazotide acetate - Drug Profile 91 Product Description 91 Mechanism of Action 91 R&D Progress 91 DA-6886 - Drug Profile 93 Product Description 93 Mechanism of Action 93 R&D Progress 93 YH-12852 - Drug Profile 94 Product Description 94 Mechanism of Action 94 R&D Progress 94 MDT-006 - Drug Profile 95 Product Description 95 Mechanism of Action 95 R&D Progress 95 RQ-00202730 - Drug Profile 96 Product Description 96 Mechanism of Action 96 R&D Progress 96 RQ-00310941 - Drug Profile 97 Product Description 97 Mechanism of Action 97 R&D Progress 97 GIC-1001 - Drug Profile 98 Product Description 98 Mechanism of Action 98 R&D Progress 98 Small Molecules to Inhibit 5-HT2B and 5-HT7 Receptors for IBS and Migraine - Drug Profile 100 Product Description 100 Mechanism of Action 100 R&D Progress 100 ASP-1017 - Drug Profile 101 Product Description 101 Mechanism of Action 101 R&D Progress 101 TAK-480 - Drug Profile 102 Product Description 102 Mechanism of Action 102 R&D Progress 102 Nexvax-2 - Drug Profile 103 Product Description 103 Mechanism of Action 103 R&D Progress 103 Synthetic Peptides for Gastrointestinal Disorders - Drug Profile 104 Product Description 104 Mechanism of Action 104 R&D Progress 104 Monoclonal Antibody to Inhibit M3 for Irritable Bowel Syndrome - Drug Profile 105 Product Description 105 Mechanism of Action 105 R&D Progress 105 SYN-007 - Drug Profile 106 Product Description 106 Mechanism of Action 106 R&D Progress 106 Peptides for Irritable Bowel Syndrome and Inflammatory Bowel Disease - Drug Profile 107 Product Description 107 Mechanism of Action 107 R&D Progress 107 Irritable Bowel Syndrome - Recent Pipeline Updates 108 Irritable Bowel Syndrome - Dormant Projects 132 Irritable Bowel Syndrome - Discontinued Products 133 Irritable Bowel Syndrome - Product Development Milestones 134 Featured News & Press Releases 134 Sep 18, 2014: Salix Announces FDA User Fee Goal Date of February 28, 2015 for XIFAXAN 550mg sNDA for Treatment of Irritable Bowel Syndrome with Diarrhea 134 Sep 02, 2014: 4D pharma Provides Update On Blautix for the treatment of Irritable Bowel Syndrome 134 Sep 02, 2014: Actavis Announces FDA Acceptance for Filing of NDA for Eluxadoline 135 Sep 02, 2014: Salix Submits Response to XIFAXAN 550mg Complete Response Letter Regarding Repeat Treatment for Irritable Bowel Syndrome with Diarrhea 136 Aug 11, 2014: Salix Announces Important Topline Results for Microbiome, Culture & Susceptibility, and Key Secondary Efficacy Results for TARGET 3, Rifaximin IBS-D Repeat Treatment Study 137 Jul 08, 2014: Synergy Pharmaceuticals Announces Successful End-of-Phase 2 Meeting with FDA for Plecanatide in Irritable Bowel Syndrome with Constipation 138 May 01, 2014: Synergy Pharmaceuticals Announces Positive Results of Plecanatide Phase 2b Study in Patients with Irritable Bowel Syndrome with Constipation 139 Apr 10, 2014: Ironwood and Forest Launch New Direct-to-Consumer Awareness Campaign For LINZESS 140 Feb 10, 2014: Ironwood Receives Notice of Allowance for Methods of Use Formulation Patent Expected to Extend LINZESS Patent Protection Through 2031 141 Feb 04, 2014: Furiex Pharmaceuticals Announces Positive Top-Line Results of Two Pivotal Phase III Clinical Trials of Eluxadoline in Patients with IBS-d 142 Appendix 145 Methodology 145 Coverage 145 Secondary Research 145 Primary Research 145 Expert Panel Validation 145 Contact Us 146 Disclaimer 146
List of Tables Number of Products under Development for Irritable Bowel Syndrome, H2 2014 11 Number of Products under Development for Irritable Bowel Syndrome - Comparative Analysis, H2 2014 12 Number of Products under Development by Companies, H2 2014 14 Comparative Analysis by Late Stage Development, H2 2014 16 Comparative Analysis by Clinical Stage Development, H2 2014 17 Comparative Analysis by Early Stage Development, H2 2014 18 Products under Development by Companies, H2 2014 19 Irritable Bowel Syndrome - Pipeline by AstraZeneca PLC., H2 2014 20 Irritable Bowel Syndrome - Pipeline by Sumitomo Dainippon Pharma Co., Ltd., H2 2014 21 Irritable Bowel Syndrome - Pipeline by Takeda Pharmaceutical Company Limited, H2 2014 22 Irritable Bowel Syndrome - Pipeline by Astellas Pharma Inc., H2 2014 23 Irritable Bowel Syndrome - Pipeline by Ono Pharmaceutical Co., Ltd., H2 2014 24 Irritable Bowel Syndrome - Pipeline by SK Chemicals Co., Ltd., H2 2014 25 Irritable Bowel Syndrome - Pipeline by Teva Pharmaceutical Industries Limited, H2 2014 26 Irritable Bowel Syndrome - Pipeline by A. Menarini Industrie Farmaceutiche Riunite Srl, H2 2014 27 Irritable Bowel Syndrome - Pipeline by AlbireoPharma, H2 2014 28 Irritable Bowel Syndrome - Pipeline by Lexicon Pharmaceuticals, Inc., H2 2014 29 Irritable Bowel Syndrome - Pipeline by Yuhan Corporation, H2 2014 30 Irritable Bowel Syndrome - Pipeline by Alba Therapeutics Corporation, H2 2014 31 Irritable Bowel Syndrome - Pipeline by Ironwood Pharmaceuticals, Inc., H2 2014 32 Irritable Bowel Syndrome - Pipeline by Rottapharm SpA, H2 2014 33 Irritable Bowel Syndrome - Pipeline by Tioga Pharmaceuticals, Inc., H2 2014 34 Irritable Bowel Syndrome - Pipeline by Synthetic Biologics, Inc., H2 2014 35 Irritable Bowel Syndrome - Pipeline by Drais Pharmaceuticals, Inc., H2 2014 36 Irritable Bowel Syndrome - Pipeline by Synergy Pharmaceuticals, Inc., H2 2014 37 Irritable Bowel Syndrome - Pipeline by Protagonist Therapeutics Inc., H2 2014 38 Irritable Bowel Syndrome - Pipeline by Alfa Wassermann S.p.A, H2 2014 39 Irritable Bowel Syndrome - Pipeline by RaQualia Pharma Inc., H2 2014 40 Irritable Bowel Syndrome - Pipeline by Furiex Pharmaceuticals, Inc., H2 2014 41 Irritable Bowel Syndrome - Pipeline by Hanmi Pharmaceuticals, Co. Ltd., H2 2014 42 Irritable Bowel Syndrome - Pipeline by X-BODY BioSciences, Inc., H2 2014 43 Irritable Bowel Syndrome - Pipeline by ImmusanT, Inc., H2 2014 44 Irritable Bowel Syndrome - Pipeline by AltheRx Pharmaceuticals, Inc., H2 2014 45 Irritable Bowel Syndrome - Pipeline by GIcare Pharma Inc, H2 2014 46 Irritable Bowel Syndrome - Pipeline by Dong-A Socio Group, H2 2014 47 Assessment by Monotherapy Products, H2 2014 48 Assessment by Combination Products, H2 2014 49 Number of Products by Stage and Target, H2 2014 52 Number of Products by Stage and Mechanism of Action, H2 2014 55 Number of Products by Stage and Route of Administration, H2 2014 58 Number of Products by Stage and Molecule Type, H2 2014 60 Irritable Bowel Syndrome Therapeutics - Recent Pipeline Updates, H2 2014 108 Irritable Bowel Syndrome - Dormant Projects, H2 2014 132 Irritable Bowel Syndrome - Discontinued Products, H2 2014 133
Speak to the report author to design an exclusive study to serve your research needs.
Your personal and confidential information is safe and secure.