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Insomnia - Pipeline Review, H1 2015

Published: Jun, 2015 | Pages: 94 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Insomnia - Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Insomnia - Pipeline Review, H1 2015', provides an overview of the Insomnia's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Insomnia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Insomnia and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Insomnia
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in the therapeutics development for Insomnia and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects 
- A review of the Insomnia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Insomnia pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Insomnia
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Insomnia pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
 Table of Contents
Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Insomnia Overview 9 Therapeutics Development 10 Pipeline Products for Insomnia - Overview 10 Pipeline Products for Insomnia - Comparative Analysis 11 Insomnia - Therapeutics under Development by Companies 12 Insomnia - Therapeutics under Investigation by Universities/Institutes 14 Insomnia - Pipeline Products Glance 15 Late Stage Products 15 Clinical Stage Products 16 Early Stage Products 17 Insomnia - Products under Development by Companies 18 Insomnia - Products under Investigation by Universities/Institutes 20 Insomnia - Companies Involved in Therapeutics Development 21 Actelion Ltd 21 Alexza Pharmaceuticals, Inc. 22 Eisai Co., Ltd. 23 Evotec AG 24 Grupo Ferrer Internacional, S.A. 25 Heptares Therapeutics Ltd. 26 Intec Pharma ltd. 27 Intra-Cellular Therapies, Inc. 28 Johnson & Johnson 29 Merck & Co., Inc. 30 Minerva Neurosciences, Inc. 31 Neurim Pharmaceuticals Ltd 32 Novartis AG 33 Reviva Pharmaceuticals Inc. 34 Rottapharm SpA 35 Shionogi & Co., Ltd. 36 Somnus Therapeutics, Inc. 37 Takeda Pharmaceutical Company Limited 38 Insomnia - Therapeutics Assessment 39 Assessment by Monotherapy Products 39 Assessment by Target 40 Assessment by Mechanism of Action 42 Assessment by Route of Administration 44 Assessment by Molecule Type 46 Drug Profiles 47 ACT-462206 - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 CR-5542 Series - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Drugs to Inhibit Angiotensin II Receptor Type 1 for Insomnia - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 EVT-201 - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 ITI-007 - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 JNJ-42847922 - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 LASSBio-785 - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 LASSBio-786 - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 lemborexant - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 lorediplon - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 MIN-202 - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 MK-8133 - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 piromelatine - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 ramelteon - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 RP-15000 - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 S-117957 - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 Small Molecule to Antagonize Orexin 1 and 2 Receptors for Insomnia - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 Small Molecule to Inhibit OX2R for Insomnia - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 UCM-765 - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 zaleplon - Drug Profile 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 zaleplon DR - Drug Profile 69 Product Description 69 Mechanism of Action 69 R&D Progress 69 zaleplon GR - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 zolpidem tartrate - Drug Profile 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 Insomnia - Recent Pipeline Updates 73 Insomnia - Dormant Projects 80 Insomnia - Discontinued Products 83 Insomnia - Product Development Milestones 85 Featured News & Press Releases 85 Jan 21, 2015: Minerva Neurosciences Reports Positive Phase 1 Data With MIN-202, Selective Orexin-2 Antagonist for Treatment of Sleep Disorders Including Primary and Comorbid Insomnia 85 Dec 10, 2014: Eisai Demonstrates Efficacy Of Investigational Dual Orexin Receptor Antagonist E2006 In Sleep Initiation And Maintenance 86 Sep 22, 2014: Minerva Neurosciences Announces Completion of FDA Review of Investigational New Drug Application for MIN-202 and Plans for First U.S.-Based Clinical Trial 87 Feb 18, 2013: Neurim Pharma Announces Positive Phase II Clinical Trial Results Of Piromelatine For Treatment Of Insomnia 87 Feb 09, 2012: Ferrer Announces Positive Results From Phase I Clinical Trials Of Lorediplon In Insomnia 88 Dec 14, 2011: McGill University Health Centre Researchers Discover Potential Insomnia Drug 89 Oct 07, 2011: Takeda Discontinues Development Of Ramelteon In Europe For Treatment Of Insomnia 90 Jul 24, 2011: Neurim Announces Positive Results From Phase I And Phase Ib Clinical Trials With Neu-P11 90 Jun 15, 2011: Somnus's Phase II Study Of SKP-1041 For Sleep Maintenance Insomnia Shows Significant Reduction Of Mid-Night Awakenings without Next-Day Cognitive Impairment 91 Jun 01, 2011: Somnus Therapeutics Completes Successful Phase II Study Of SKP-1041 For Sleep Maintenance Insomnia 92 Appendix 93 Methodology 93 Coverage 93 Secondary Research 93 Primary Research 93 Expert Panel Validation 93 Contact Us 93 Disclaimer 94
List of Tables
Number of Products under Development for Insomnia, H1 2015 10 Number of Products under Development for Insomnia - Comparative Analysis, H1 2015 11 Number of Products under Development by Companies, H1 2015 13 Number of Products under Investigation by Universities/Institutes, H1 2015 14 Comparative Analysis by Late Stage Development, H1 2015 15 Comparative Analysis by Clinical Stage Development, H1 2015 16 Comparative Analysis by Early Stage Development, H1 2015 17 Products under Development by Companies, H1 2015 18 Products under Development by Companies, H1 2015 (Contd..1) 19 Products under Investigation by Universities/Institutes, H1 2015 20 Insomnia - Pipeline by Actelion Ltd, H1 2015 21 Insomnia - Pipeline by Alexza Pharmaceuticals, Inc., H1 2015 22 Insomnia - Pipeline by Eisai Co., Ltd., H1 2015 23 Insomnia - Pipeline by Evotec AG, H1 2015 24 Insomnia - Pipeline by Grupo Ferrer Internacional, S.A., H1 2015 25 Insomnia - Pipeline by Heptares Therapeutics Ltd., H1 2015 26 Insomnia - Pipeline by Intec Pharma ltd., H1 2015 27 Insomnia - Pipeline by Intra-Cellular Therapies, Inc., H1 2015 28 Insomnia - Pipeline by Johnson & Johnson, H1 2015 29 Insomnia - Pipeline by Merck & Co., Inc., H1 2015 30 Insomnia - Pipeline by Minerva Neurosciences, Inc., H1 2015 31 Insomnia - Pipeline by Neurim Pharmaceuticals Ltd, H1 2015 32 Insomnia - Pipeline by Novartis AG, H1 2015 33 Insomnia - Pipeline by Reviva Pharmaceuticals Inc., H1 2015 34 Insomnia - Pipeline by Rottapharm SpA, H1 2015 35 Insomnia - Pipeline by Shionogi & Co., Ltd., H1 2015 36 Insomnia - Pipeline by Somnus Therapeutics, Inc., H1 2015 37 Insomnia - Pipeline by Takeda Pharmaceutical Company Limited, H1 2015 38 Assessment by Monotherapy Products, H1 2015 39 Number of Products by Stage and Target, H1 2015 41 Number of Products by Stage and Mechanism of Action, H1 2015 43 Number of Products by Stage and Route of Administration, H1 2015 45 Number of Products by Stage and Molecule Type, H1 2015 46 Insomnia Therapeutics - Recent Pipeline Updates, H1 2015 73 Insomnia - Dormant Projects, H1 2015 80 Insomnia - Dormant Projects (Contd..1), H1 2015 81 Insomnia - Dormant Projects (Contd..2), H1 2015 82 Insomnia - Discontinued Products, H1 2015 83 Insomnia - Discontinued Products (Contd..1), H1 2015 84



                                

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