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Published: Oct, 2014 | Pages:
157 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Indolent Lymphoma - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Indolent Lymphoma - Pipeline Review, H2 2014', provides an overview of the Indolent Lymphoma's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Indolent Lymphoma, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Indolent Lymphoma and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Indolent Lymphoma - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Indolent Lymphoma and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Indolent Lymphoma products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Indolent Lymphoma pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Indolent Lymphoma - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Indolent Lymphoma pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Indolent Lymphoma Overview 9 Therapeutics Development 10 Pipeline Products for Indolent Lymphoma - Overview 10 Pipeline Products for Indolent Lymphoma - Comparative Analysis 11 Indolent Lymphoma - Therapeutics under Development by Companies 12 Indolent Lymphoma - Pipeline Products Glance 14 Late Stage Products 14 Clinical Stage Products 15 Unknown Stage Products 16 Indolent Lymphoma - Products under Development by Companies 17 Indolent Lymphoma - Companies Involved in Therapeutics Development 18 Amgen Inc. 18 Astellas Pharma Inc. 19 Bayer AG 20 BioMedics Japan Inc. 21 Biothera, Inc. 22 Boehringer Ingelheim GmbH 23 Celgene Corporation 24 Eagle Pharmaceuticals Inc. 25 Emergent BioSolutions Inc. 26 F. Hoffmann-La Roche Ltd. 27 Gilead Sciences, Inc. 28 Incyte Corporation 29 Infinity Pharmaceuticals, Inc. 30 Kite Pharma, Inc. 31 MedImmune, LLC 32 Merck & Co., Inc. 33 Merck KGaA 34 MorphoSys AG 35 Pharmacyclics, Inc. 36 Sandoz Inc. 37 Indolent Lymphoma - Therapeutics Assessment 38 Assessment by Monotherapy Products 38 Assessment by Combination Products 39 Assessment by Target 40 Assessment by Mechanism of Action 42 Assessment by Route of Administration 44 Assessment by Molecule Type 46 Drug Profiles 48 bendamustine hydrochloride - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 bendamustine hydrochloride SI - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 BI-836826 - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 blinatumomab - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 BM-ca - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 copanlisib - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 DI-B4 - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 duvelisib - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 GS-9973 - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 ibrutinib - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 idelalisib - Drug Profile 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 Imprime PGG - Drug Profile 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 INCB-050465 - Drug Profile 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 INCB-40093 - Drug Profile 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 INCB-40093 + INCB-39110 - Drug Profile 76 Product Description 76 Mechanism of Action 76 R&D Progress 76 JCAR-015 - Drug Profile 77 Product Description 77 Mechanism of Action 77 R&D Progress 77 KTE-C19 CAR - Drug Profile 79 Product Description 79 Mechanism of Action 79 R&D Progress 79 lenalidomide - Drug Profile 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 MEDI-551 - Drug Profile 84 Product Description 84 Mechanism of Action 84 R&D Progress 84 MOR-208 - Drug Profile 86 Product Description 86 Mechanism of Action 86 R&D Progress 86 obinutuzumab - Drug Profile 88 Product Description 88 Mechanism of Action 88 R&D Progress 88 otlertuzumab - Drug Profile 90 Product Description 90 Mechanism of Action 90 R&D Progress 90 rituximab biosimilar - Drug Profile 92 Product Description 92 Mechanism of Action 92 R&D Progress 92 vorinostat - Drug Profile 93 Product Description 93 Mechanism of Action 93 R&D Progress 93 Indolent Lymphoma - Recent Pipeline Updates 97 Indolent Lymphoma - Dormant Projects 141 Indolent Lymphoma - Discontinued Products 142 Indolent Lymphoma - Product Development Milestones 143 Featured News & Press Releases 143 Apr 07, 2014: Research Expands Understanding of Biomarker for Biothera Cancer Immunotherapy Imprime PGG 143 Jan 22, 2014: New drug shows promise in treating indolent non-Hodgkin lymphomas 144 Dec 10, 2013: Studies Evaluating REVLIMID (Lenalidomide) in Lymphoma Presented at ASH 145 Dec 08, 2013: Gilead Announces Pivotal Phase 2 Data for Idelalisib in Refractory Indolent Non-Hodgkin's Lymphoma 146 Feb 20, 2013: Mundipharma Reports Publication Of Phase III Data Of Bendamustine Plus Rituximab In Lancet 148 Dec 10, 2012: Infinity Pharma Reports IPI-145 Phase I Data Showing Clinical Activity In B-Cell And T-Cell Malignancies At ASH Annual Meeting 149 Dec 03, 2012: Mundipharma Announces Acceptance Of Bendamustine Abstracts At Annual Meeting Of American Society Of Hematology 150 Dec 07, 2010: Celgene Presents Clinical Data From Two Phase II Studies Evaluating REVLIMID Plus Rituximab In Indolent Non-Hodgkin's Lymphomas At ASH 152 Dec 05, 2010: Calistoga Reports Positive Phase I interim Results From Combination Trial Of CAL-101 In Hematologic Malignancies 153 Dec 05, 2010: Calistoga Reports Positive Results From CAL-101 Phase I Trial In Hematologic Malignancies 154 Appendix 156 Methodology 156 Coverage 156 Secondary Research 156 Primary Research 156 Expert Panel Validation 156 Contact Us 157 Disclaimer 157
List of Tables Number of Products under Development for Indolent Lymphoma, H2 2014 10 Number of Products under Development for Indolent Lymphoma - Comparative Analysis, H2 2014 11 Number of Products under Development by Companies, H2 2014 13 Comparative Analysis by Late Stage Development, H2 2014 14 Comparative Analysis by Clinical Stage Development, H2 2014 15 Comparative Analysis by Unknown Stage Development, H2 2014 16 Products under Development by Companies, H2 2014 17 Indolent Lymphoma - Pipeline by Amgen Inc., H2 2014 18 Indolent Lymphoma - Pipeline by Astellas Pharma Inc., H2 2014 19 Indolent Lymphoma - Pipeline by Bayer AG, H2 2014 20 Indolent Lymphoma - Pipeline by BioMedics Japan Inc., H2 2014 21 Indolent Lymphoma - Pipeline by Biothera, Inc., H2 2014 22 Indolent Lymphoma - Pipeline by Boehringer Ingelheim GmbH, H2 2014 23 Indolent Lymphoma - Pipeline by Celgene Corporation, H2 2014 24 Indolent Lymphoma - Pipeline by Eagle Pharmaceuticals Inc., H2 2014 25 Indolent Lymphoma - Pipeline by Emergent BioSolutions Inc., H2 2014 26 Indolent Lymphoma - Pipeline by F. Hoffmann-La Roche Ltd., H2 2014 27 Indolent Lymphoma - Pipeline by Gilead Sciences, Inc., H2 2014 28 Indolent Lymphoma - Pipeline by Incyte Corporation, H2 2014 29 Indolent Lymphoma - Pipeline by Infinity Pharmaceuticals, Inc., H2 2014 30 Indolent Lymphoma - Pipeline by Kite Pharma, Inc., H2 2014 31 Indolent Lymphoma - Pipeline by MedImmune, LLC, H2 2014 32 Indolent Lymphoma - Pipeline by Merck & Co., Inc., H2 2014 33 Indolent Lymphoma - Pipeline by Merck KGaA, H2 2014 34 Indolent Lymphoma - Pipeline by MorphoSys AG, H2 2014 35 Indolent Lymphoma - Pipeline by Pharmacyclics, Inc., H2 2014 36 Indolent Lymphoma - Pipeline by Sandoz Inc., H2 2014 37 Assessment by Monotherapy Products, H2 2014 38 Assessment by Combination Products, H2 2014 39 Number of Products by Stage and Target, H2 2014 41 Number of Products by Stage and Mechanism of Action, H2 2014 43 Number of Products by Stage and Route of Administration, H2 2014 45 Number of Products by Stage and Molecule Type, H2 2014 47 Indolent Lymphoma Therapeutics - Recent Pipeline Updates, H2 2014 97 Indolent Lymphoma - Dormant Projects, H2 2014 141 Indolent Lymphoma - Discontinued Products, H2 2014 142
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