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Published: Nov, 2016 | Pages:
214 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Hypercholesterolemia - Pipeline Review, H2 2016 Summary Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Hypercholesterolemia - Pipeline Review, H2 2016, provides an overview of the Hypercholesterolemia (Metabolic Disorders) pipeline landscape. Hypercholesterolemia arises due to high levels of cholesterol in the blood. These abnormal levels may lead to various diseases especially cardiovascular diseases. Cholesterol deposit in the arteries and may cause the narrowing of blood vessels hence restricting the blood flow. The predisposing factors for hypercholesterolemia include various diseases such as diabetes mellitus, renal diseases, obesity etc. The other factors involved are heredity, certain drugs, sedentary lifestyle, smoking, alcoholism, stress and high fat diet. The symptoms for hypercholesterolemia include blocked arteries, leg pain, chest pain and cholesterol deposits. The disease can be controlled by lifestyle changes, dietary changes, and medications. Report Highlights Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Hypercholesterolemia - Pipeline Review, H2 2016, provides comprehensive information on the therapeutics under development for Hypercholesterolemia (Metabolic Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. The Hypercholesterolemia (Metabolic Disorders) pipeline guide also reviews of key players involved in therapeutic development for Hypercholesterolemia and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 11, 13, 5, 1, 17, 8 and 1 respectively. Similarly, the Universities portfolio in Preclinical and Discovery stages comprises 7 and 2 molecules, respectively.Hypercholesterolemia. Hypercholesterolemia (Metabolic Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data. Scope - The pipeline guide provides a snapshot of the global therapeutic landscape of Hypercholesterolemia (Metabolic Disorders). - The pipeline guide reviews pipeline therapeutics for Hypercholesterolemia (Metabolic Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources. - The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages. - The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities. - The pipeline guide reviews key companies involved in Hypercholesterolemia (Metabolic Disorders) therapeutics and enlists all their major and minor projects. - The pipeline guide evaluates Hypercholesterolemia (Metabolic Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. - The pipeline guide encapsulates all the dormant and discontinued pipeline projects. - The pipeline guide reviews latest news related to pipeline therapeutics for Hypercholesterolemia (Metabolic Disorders) Reasons To Buy - Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies. - Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage. - Find and recognize significant and varied types of therapeutics under development for Hypercholesterolemia (Metabolic Disorders). - Classify potential new clients or partners in the target demographic. - Develop tactical initiatives by understanding the focus areas of leading companies. - Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics. - Formulate corrective measures for pipeline projects by understanding Hypercholesterolemia (Metabolic Disorders) pipeline depth and focus of Indication therapeutics. - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope. - Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
Table of Contents
Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Hypercholesterolemia Overview 9 Therapeutics Development 10 Pipeline Products for Hypercholesterolemia - Overview 10 Pipeline Products for Hypercholesterolemia - Comparative Analysis 11 Hypercholesterolemia - Therapeutics under Development by Companies 12 Hypercholesterolemia - Therapeutics under Investigation by Universities/Institutes 15 Hypercholesterolemia - Pipeline Products Glance 16 Late Stage Products 16 Clinical Stage Products 17 Early Stage Products 18 Unknown Stage Products 19 Hypercholesterolemia - Products under Development by Companies 20 Hypercholesterolemia - Products under Investigation by Universities/Institutes 24 Hypercholesterolemia - Companies Involved in Therapeutics Development 25 3SBio Inc 25 AFFiRiS AG 26 Akcea Therapeutics Inc 27 Alvogen Korea Co Ltd 28 ARMO Biosciences Inc 29 AstraZeneca Plc 30 BioLingus AG 31 Catabasis Pharmaceuticals Inc 32 Chong Kun Dang Pharmaceutical Corp 33 CymaBay Therapeutics Inc 34 Daewon Pharm Co Ltd 35 Dicerna Pharmaceuticals Inc 36 Dybly AG 37 Esperion Therapeutics Inc 38 Gemphire Therapeutics Inc 39 Golden Biotechnology Corp 40 Hanmi Pharmaceuticals Co Ltd 41 Immune Response BioPharma Inc 42 Johnson & Johnson 43 Kadmon Corp LLC 44 Kyorin Pharmaceutical Co Ltd 45 Leading BioSciences Inc 46 LipimetiX Development Inc 47 Lotus Pharmaceutical Co Ltd 48 Merck & Co Inc 49 Pfizer Inc 50 Planet Biotechnology Inc 51 Progenra Inc 52 Regeneron Pharmaceuticals Inc 53 RegenxBio Inc 54 Serometrix LLC 55 Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd 56 Solvotrin Therapeutics Ltd 57 The Medicines Company 58 Thetis Pharmaceuticals LLC 59 Viking Therapeutics Inc 60 Zhejiang Hisun Pharmaceutical Co Ltd 61 Hypercholesterolemia - Therapeutics Assessment 62 Assessment by Monotherapy Products 62 Assessment by Combination Products 63 Assessment by Target 64 Assessment by Mechanism of Action 67 Assessment by Route of Administration 70 Assessment by Molecule Type 72 Drug Profiles 74 (aspirin + lisinopril + lovastatin) - Drug Profile 74 (atorvastatin calcium + ezetimibe) - Drug Profile 75 (atorvastatin calcium + ezetimibe) - Drug Profile 76 (atorvastatin calcium + TP-452) - Drug Profile 77 (bempedoic acid + ezetimibe) - Drug Profile 78 (candesartan cilexetil + rosuvastatin calcium) - Drug Profile 79 (ezetimibe + rosuvastatin calcium) - Drug Profile 80 AEM-28 - Drug Profile 81 AEM-2802 - Drug Profile 83 AEM-2814 - Drug Profile 84 alirocumab - Drug Profile 85 AM-0010 - Drug Profile 96 anacetrapib - Drug Profile 99 Antibodies for Metabolic Disorders - Drug Profile 101 Antisense Oligonucleotide to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 102 Antisense Oligonucleotides to Inhibit ApoB100 for Familial Hypercholesterolemia - Drug Profile 103 antroquinonol - Drug Profile 104 ATH-04 - Drug Profile 106 ATH-06 - Drug Profile 107 bempedoic acid - Drug Profile 108 BSN-272 - Drug Profile 118 CAT-2000 Series - Drug Profile 119 CAT-2003 - Drug Profile 120 colestilan chloride - Drug Profile 123 D-4F - Drug Profile 124 DCRPCSK-9 - Drug Profile 125 Drugs for Hypercholesterolemia - Drug Profile 126 Drugs to Inhibit Sortilin for Hypercholesterolemia - Drug Profile 127 DW-0929 - Drug Profile 128 DW-3102 - Drug Profile 129 DYB-186 - Drug Profile 130 EP-80317 - Drug Profile 131 evinacumab - Drug Profile 132 gemcabene calcium - Drug Profile 134 Gene Therapy to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 136 HCP-1305 - Drug Profile 137 HGP-0816 - Drug Profile 138 HS-25 - Drug Profile 139 inclisiran - Drug Profile 140 IONIS-ANGPTL3LRx - Drug Profile 144 IR-1002 - Drug Profile 145 KD-026 - Drug Profile 146 MBX-8025 - Drug Profile 147 MGL-3196 - Drug Profile 150 MGL-3745 - Drug Profile 152 MN-002 - Drug Profile 153 Monoclonal Antibodies to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 154 Monoclonal Antibody to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 155 PF-06446846 - Drug Profile 156 Recombinant Protein to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 157 RGX-501 - Drug Profile 158 rosuvastatin calcium - Drug Profile 160 Small Molecule for Hypercholesterolemia - Drug Profile 161 Small Molecule to Inhibit Endothelial Lipase for Hypercholesterolemia - Drug Profile 162 Small Molecule to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 163 Small Molecule to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 164 Small Molecules to Inhibit IDOL for Hypercholesterolemia - Drug Profile 165 Small Molecules to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 166 Small Molecules to Target O2 Radical and HMGCR for Ophthalmology, Cardiovascular, CNS and Metabolic Disorders - Drug Profile 167 ST-0702 - Drug Profile 169 SX-PCK9 - Drug Profile 170 Synthetic Peptide to Inhibit PCSK9 for Hypercholesterolemia - Drug Profile 171 Vaccine to Target PCSK9 for Hypercholesterolemia - Drug Profile 172 VK-2809 - Drug Profile 173 volanesorsen sodium - Drug Profile 176 Hypercholesterolemia - Dormant Projects 182 Hypercholesterolemia - Discontinued Products 189 Hypercholesterolemia - Product Development Milestones 191 Featured News & Press Releases 191 Appendix 208 Methodology 208 Coverage 208 Secondary Research 208 Primary Research 208 Expert Panel Validation 208 Contact Us 208 Disclaimer 209
List of Tables
Number of Products under Development for Hypercholesterolemia, H2 2016 15 Number of Products under Development for Hypercholesterolemia - Comparative Analysis, H2 2016 16 Number of Products under Development by Companies, H2 2016 17 Number of Products under Development by Companies, H2 2016 (Contd..1) 18 Number of Products under Development by Companies, H2 2016 (Contd..2) 19 Number of Products under Investigation by Universities/Institutes, H2 2016 20 Comparative Analysis by Late Stage Development, H2 2016 21 Comparative Analysis by Clinical Stage Development, H2 2016 22 Comparative Analysis by Early Stage Development, H2 2016 23 Comparative Analysis by Unknown Stage Development, H2 2016 24 Products under Development by Companies, H2 2016 25 Products under Development by Companies, H2 2016 (Contd..1) 26 Products under Development by Companies, H2 2016 (Contd..2) 27 Products under Development by Companies, H2 2016 (Contd..3) 28 Products under Investigation by Universities/Institutes, H2 2016 29 Hypercholesterolemia - Pipeline by 3SBio Inc, H2 2016 30 Hypercholesterolemia - Pipeline by AFFiRiS AG, H2 2016 31 Hypercholesterolemia - Pipeline by Akcea Therapeutics Inc, H2 2016 32 Hypercholesterolemia - Pipeline by Alvogen Korea Co Ltd, H2 2016 33 Hypercholesterolemia - Pipeline by ARMO Biosciences Inc, H2 2016 34 Hypercholesterolemia - Pipeline by AstraZeneca Plc, H2 2016 35 Hypercholesterolemia - Pipeline by BioLingus AG, H2 2016 36 Hypercholesterolemia - Pipeline by Catabasis Pharmaceuticals Inc, H2 2016 37 Hypercholesterolemia - Pipeline by Chong Kun Dang Pharmaceutical Corp, H2 2016 38 Hypercholesterolemia - Pipeline by CymaBay Therapeutics Inc, H2 2016 39 Hypercholesterolemia - Pipeline by Daewon Pharm Co Ltd, H2 2016 40 Hypercholesterolemia - Pipeline by Dicerna Pharmaceuticals Inc, H2 2016 41 Hypercholesterolemia - Pipeline by Dybly AG, H2 2016 42 Hypercholesterolemia - Pipeline by Esperion Therapeutics Inc, H2 2016 43 Hypercholesterolemia - Pipeline by Gemphire Therapeutics Inc, H2 2016 44 Hypercholesterolemia - Pipeline by Golden Biotechnology Corp, H2 2016 45 Hypercholesterolemia - Pipeline by Hanmi Pharmaceuticals Co Ltd, H2 2016 46 Hypercholesterolemia - Pipeline by Immune Response BioPharma Inc, H2 2016 47 Hypercholesterolemia - Pipeline by Johnson & Johnson, H2 2016 48 Hypercholesterolemia - Pipeline by Kadmon Corp LLC, H2 2016 49 Hypercholesterolemia - Pipeline by Kyorin Pharmaceutical Co Ltd, H2 2016 50 Hypercholesterolemia - Pipeline by Leading BioSciences Inc, H2 2016 51 Hypercholesterolemia - Pipeline by LipimetiX Development Inc, H2 2016 52 Hypercholesterolemia - Pipeline by Lotus Pharmaceutical Co Ltd, H2 2016 53 Hypercholesterolemia - Pipeline by Merck & Co Inc, H2 2016 54 Hypercholesterolemia - Pipeline by Pfizer Inc, H2 2016 55 Hypercholesterolemia - Pipeline by Planet Biotechnology Inc, H2 2016 56 Hypercholesterolemia - Pipeline by Progenra Inc, H2 2016 57 Hypercholesterolemia - Pipeline by Regeneron Pharmaceuticals Inc, H2 2016 58 Hypercholesterolemia - Pipeline by RegenxBio Inc, H2 2016 59 Hypercholesterolemia - Pipeline by Serometrix LLC, H2 2016 60 Hypercholesterolemia - Pipeline by Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd, H2 2016 61 Hypercholesterolemia - Pipeline by Solvotrin Therapeutics Ltd, H2 2016 62 Hypercholesterolemia - Pipeline by The Medicines Company, H2 2016 63 Hypercholesterolemia - Pipeline by Thetis Pharmaceuticals LLC, H2 2016 64 Hypercholesterolemia - Pipeline by Viking Therapeutics Inc, H2 2016 65 Hypercholesterolemia - Pipeline by Zhejiang Hisun Pharmaceutical Co Ltd, H2 2016 66 Assessment by Monotherapy Products, H2 2016 67 Assessment by Combination Products, H2 2016 68 Number of Products by Stage and Target, H2 2016 70 Number of Products by Stage and Mechanism of Action, H2 2016 73 Number of Products by Stage and Route of Administration, H2 2016 76 Number of Products by Stage and Molecule Type, H2 2016 78 Hypercholesterolemia - Dormant Projects, H2 2016 187 Hypercholesterolemia - Dormant Projects (Contd..1), H2 2016 188 Hypercholesterolemia - Dormant Projects (Contd..2), H2 2016 189 Hypercholesterolemia - Dormant Projects (Contd..3), H2 2016 190 Hypercholesterolemia - Dormant Projects (Contd..4), H2 2016 191 Hypercholesterolemia - Dormant Projects (Contd..5), H2 2016 192 Hypercholesterolemia - Dormant Projects (Contd..6), H2 2016 193 Hypercholesterolemia - Discontinued Products, H2 2016 194 Hypercholesterolemia - Discontinued Products (Contd..1), H2 2016 195
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