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Hepatic Encephalopathy - Pipeline Review, H1 2016

Published: Feb, 2016 | Pages: 63 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Hepatic Encephalopathy - Pipeline Review, H1 2016

Summary
Global Markets Direct's, 'Hepatic Encephalopathy - Pipeline Review, H1 2016', provides an overview of the Hepatic Encephalopathy pipeline landscape. The report provides comprehensive information on the therapeutics under development for Hepatic Encephalopathy, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Hepatic Encephalopathy and features dormant and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data. Scope - The report provides a snapshot of the global therapeutic landscape of Hepatic Encephalopathy - The report reviews pipeline therapeutics for Hepatic Encephalopathy by companies and universities/research institutes based on information derived from company and industry-specific sources - The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages - The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved Hepatic Encephalopathy therapeutics and enlists all their major and minor projects - The report assesses Hepatic Encephalopathy therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type - The report summarizes all the dormant and discontinued pipeline projects - The report reviews latest news related to pipeline therapeutics for Hepatic Encephalopathy Reasons to buy
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Identify and understand important and diverse types of therapeutics under development for Hepatic Encephalopathy - Identify potential new clients or partners in the target demographic - Develop strategic initiatives by understanding the focus areas of leading companies - Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics - Devise corrective measures for pipeline projects by understanding Hepatic Encephalopathy pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
 Table of Contents
Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Hepatic Encephalopathy Overview 6 Therapeutics Development 7 Pipeline Products for Hepatic Encephalopathy - Overview 7 Hepatic Encephalopathy - Therapeutics under Development by Companies 8 Hepatic Encephalopathy - Pipeline Products Glance 9 Late Stage Products 9 Clinical Stage Products 10 Early Stage Products 11 Unknown Stage Products 12 Hepatic Encephalopathy - Products under Development by Companies 13 Hepatic Encephalopathy - Companies Involved in Therapeutics Development 14 Alfa Wassermann S.p.A 14 Cosmo Pharmaceuticals S.p.A 15 Horizon Pharma Plc 16 KannaLife Sciences, Inc. 17 Ocera Therapeutics, Inc. 18 Rebiotix Inc. 19 Spherium Biomed S.L. 20 Umecrine Cognition AB 21 Hepatic Encephalopathy - Therapeutics Assessment 22 Assessment by Monotherapy Products 22 Assessment by Target 23 Assessment by Mechanism of Action 25 Assessment by Route of Administration 27 Assessment by Molecule Type 29 Drug Profiles 31 glycerol phenylbutyrate - Drug Profile 31 Product Description 31 Mechanism of Action 31 R&D Progress 31 GR-3027 - Drug Profile 35 Product Description 35 Mechanism of Action 35 R&D Progress 35 KLS-13019 - Drug Profile 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 ornithine phenylacetate - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 RBX-2477 - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 rifamycin CR - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 rifaximin - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 THDP-17 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 Hepatic Encephalopathy - Recent Pipeline Updates 45 Hepatic Encephalopathy - Dormant Projects 54 Hepatic Encephalopathy - Product Development Milestones 55 Featured News & Press Releases 55 Jan 08, 2016: Ocera Announces Complete Plasma Data From Pilot Phase 1 Study for Orally-Available OCR-002 in Development for the Prevention of Chronic Hepatic Encephalopathy 55 Nov 16, 2015: Ocera Announces Positive Phase 1 Results for Oral OCR-002 in Development for the Prevention of Chronic Hepatic Encephalopathy 55 Sep 16, 2015: Ocera Initiates Phase 1 Clinical Trial of Oral Drug Candidate OCR-002 for Prevention of Hepatic Encephalopathy 56 Aug 11, 2015: Kannalife Sciences Discusses Orphan Drug Opportunity for KLS-13019 57 Apr 20, 2015: Lupin Launches Zaxine in Canada 58 Apr 01, 2015: Ocera Completes Interim Analysis of OCR-002 in Phase 2b STOP-HE Study for the Treatment of Acute Hepatic Encephalopathy 58 Sep 18, 2014: Salix Secures Additional Intellectual Property Relating to Rifaximin 59 Sep 12, 2014: Lupin and Salix Announce Exclusive Distribution Agreement for Zaxine in Canada 59 Feb 25, 2014: Hyperion Therapeutics Announces the Publication of Phase 2 Results of Glycerol Phenylbutyrate for the Treatment of Hepatic Encephalopathy in Hepatology 60 Feb 14, 2014: Luxembourg National Health Fund Approves Reimbursement Of Xifaxan 550 60 Appendix 62 Methodology 62 Coverage 62 Secondary Research 62 Primary Research 62 Expert Panel Validation 62 Contact Us 62 Disclaimer 63
List of Tables
Number of Products under Development for Hepatic Encephalopathy, H1 2016 7 Number of Products under Development by Companies, H1 2016 8 Comparative Analysis by Late Stage Development, H1 2016 9 Comparative Analysis by Clinical Stage Development, H1 2016 10 Comparative Analysis by Early Stage Development, H1 2016 11 Comparative Analysis by Unknown Stage Development, H1 2016 12 Products under Development by Companies, H1 2016 13 Hepatic Encephalopathy - Pipeline by Alfa Wassermann S.p.A, H1 2016 14 Hepatic Encephalopathy - Pipeline by Cosmo Pharmaceuticals S.p.A, H1 2016 15 Hepatic Encephalopathy - Pipeline by Horizon Pharma Plc, H1 2016 16 Hepatic Encephalopathy - Pipeline by KannaLife Sciences, Inc., H1 2016 17 Hepatic Encephalopathy - Pipeline by Ocera Therapeutics, Inc., H1 2016 18 Hepatic Encephalopathy - Pipeline by Rebiotix Inc., H1 2016 19 Hepatic Encephalopathy - Pipeline by Spherium Biomed S.L., H1 2016 20 Hepatic Encephalopathy - Pipeline by Umecrine Cognition AB, H1 2016 21 Assessment by Monotherapy Products, H1 2016 22 Number of Products by Stage and Target, H1 2016 24 Number of Products by Stage and Mechanism of Action, H1 2016 26 Number of Products by Stage and Route of Administration, H1 2016 28 Number of Products by Stage and Molecule Type, H1 2016 30 Hepatic Encephalopathy Therapeutics - Recent Pipeline Updates, H1 2016 45 Hepatic Encephalopathy - Dormant Projects, H1 2016 54



                                

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