Hemophilia B - Pipeline Review, H1 2017

Published: Apr, 2017 | Pages: 112 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Hemophilia B - Pipeline Review, H1 2017, provides an overview of the Hemophilia B (Hematological Disorders) pipeline landscape.

Hemophilia B is a hereditary bleeding disorder caused by a lack of blood clotting factor IX. Symptoms include bleeding into joints and associated pain and swelling, bruising, excessive bleeding following circumcision, gastrointestinal tract and urinary tract hemorrhage and nosebleeds. Treatment includes replacing the defective clotting factor.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Hemophilia B - Pipeline Review, H1 2017, provides comprehensive information on the therapeutics under development for Hemophilia B (Hematological Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Hemophilia B (Hematological Disorders) pipeline guide also reviews of key players involved in therapeutic development for Hemophilia B and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical and Discovery stages are 2, 2, 9, 4, 2, 7 and 3 respectively. Similarly, the Universities portfolio in Preclinical and Discovery stages comprises 2 and 1 molecules, respectively.

Hemophilia B (Hematological Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The pipeline guide provides a snapshot of the global therapeutic landscape of Hemophilia B (Hematological Disorders).
- The pipeline guide reviews pipeline therapeutics for Hemophilia B (Hematological Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Hemophilia B (Hematological Disorders) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Hemophilia B (Hematological Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
- The pipeline guide reviews latest news related to pipeline therapeutics for Hemophilia B (Hematological Disorders)

Reasons To Buy

- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Hemophilia B (Hematological Disorders).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Hemophilia B (Hematological Disorders) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

 Table of Contents

List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Hemophilia B - Overview
Hemophilia B - Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Hemophilia B - Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Hemophilia B - Companies Involved in Therapeutics Development
Alnylam Pharmaceuticals Inc
Amarna Therapeutics BV
Bayer AG
Bioverativ Inc
Catalyst Biosciences Inc
China Biologic Products Inc
CSL Ltd
Dimension Therapeutics Inc
Genethon SA
Green Cross Corp
MolMed SpA
Novo Nordisk A/S
OPKO Biologics Ltd
Pfizer Inc
Pharming Group NV
Promethera Biosciences SA
RegenxBio Inc
rEVO Biologics Inc
Sangamo Therapeutics Inc
Shire Plc
Spark Therapeutics Inc
UniQure NV
Hemophilia B - Drug Profiles
AMT-060 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
BAX-335 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
BAY-1093884 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
BIVV-002 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
CB-2679d - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Cell Therapy for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
coagulation factor IX (human) - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
coagulation factor IX (recombinant), pegylated - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
coagulation factor VIIa (recombinant) - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
concizumab - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
CSL-689 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
DTX-101 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
fitusiran - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy for Hematological Disorders - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy to Activate Coagulation Factor IX for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy to Activate Coagulation Factor IX for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy to Activate Factor IX  for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy to Activate Factor IX for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy to Activate Factor IX for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
HepaStem - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
LR-769 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
marzeptacog alfa - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
MG-1113A - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
MOD-5014 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
PF-06741086 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Recombinant Factor IX Replacement for Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Recombinant Protein to Inhibit Coagulation Factor XIV for Hemophilia A and Hemophilia B - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
SB-FIX - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
SPK-9001 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
SVF-VIIa - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Hemophilia B - Dormant Projects
Hemophilia B - Discontinued Products
Hemophilia B - Product Development Milestones
Featured News & Press Releases
Apr 11, 2017: Key Milestone Reached in Catalyst's Subcutaneous Factor IX Program
Mar 31, 2017: FDA posts briefing materials prior to Advisory Committee meeting for nonacog beta pegol, a long-acting factor IX for the treatment of haemophilia B
Mar 30, 2017: Catalyst Biosciences Announces Emergence from Key Patent Opposition Period Supporting Marzeptacog Alfa (activated), Catalyst's Lead Clinical Program
Mar 28, 2017: Catalyst Biosciences Announces IND Approval in South Korea for Next-Generation Subcutaneous Factor IX Program
Mar 23, 2017: Novo Nordisk Receives CHMP Positive opinion For Refixia
Mar 02, 2017: Long-term safety and efficacy extension study data of Alprolix for haemophilia B published in Thrombosis and Haemostasis
Feb 14, 2017: Catalyst Biosciences Highlights Hemophilia Clinical Development Plans at the 19th Annual BIO CEO & Investor Conference
Feb 02, 2017: Long-term safety and efficacy data of extended half-life therapy Alprolix in children with haemophilia B published in The Lancet Haematology
Feb 02, 2017: Alnylam Presents New Data on Fitusiran at EAHAD
Feb 01, 2017: Catalyst Biosciences Announces Positive Preclinical Data of Subcutaneously Dosed Coagulation Factor IX at EAHAD Annual Congress
Feb 01, 2017: Sobi and Bioverativ to reveal new long-term safety and efficacy data of Alprolix at EAHAD
Feb 01, 2017: Catalyst Biosciences Announces Positive Preclinical Data of Subcutaneously Dosed Coagulation Factor VIIa at EAHAD Annual Congress
Jan 26, 2017: Catalyst Biosciences Announces Presentation on investigational coagulation factor CB 2679d at the 2017 Congress of the European Association of Haemophilia and Allied Disorders
Jan 26, 2017: Catalyst Biosciences Announces Data Presentation on Marzeptacog alfa at the 2017 Congress of the European Association of Haemophilia and Allied Disorders
Jan 06, 2017: FDA Accepts For Review LFB's BLA For Its Recombinant Factor VII
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer

List of Tables

Number of Products under Development for Hemophilia B, H1 2017
Number of Products under Development by Companies, H1 2017
Number of Products under Development by Companies, H1 2017 (Contd..1), H1 2017
Number of Products under Development by Universities/Institutes, H1 2017
Products under Development by Companies, H1 2017
Products under Development by Companies, H1 2017 (Contd..1), H1 2017
Products under Development by Universities/Institutes, H1 2017
Number of Products by Stage and Target, H1 2017
Number of Products by Stage and Mechanism of Action, H1 2017
Number of Products by Stage and Route of Administration, H1 2017
Number of Products by Stage and Molecule Type, H1 2017
Hemophilia B - Pipeline by Alnylam Pharmaceuticals Inc, H1 2017
Hemophilia B - Pipeline by Amarna Therapeutics BV, H1 2017
Hemophilia B - Pipeline by Bayer AG, H1 2017
Hemophilia B - Pipeline by Bioverativ Inc, H1 2017
Hemophilia B - Pipeline by Catalyst Biosciences Inc, H1 2017
Hemophilia B - Pipeline by China Biologic Products Inc, H1 2017
Hemophilia B - Pipeline by CSL Ltd, H1 2017
Hemophilia B - Pipeline by Dimension Therapeutics Inc, H1 2017
Hemophilia B - Pipeline by Genethon SA, H1 2017
Hemophilia B - Pipeline by Green Cross Corp, H1 2017
Hemophilia B - Pipeline by MolMed SpA, H1 2017
Hemophilia B - Pipeline by Novo Nordisk A/S, H1 2017
Hemophilia B - Pipeline by OPKO Biologics Ltd, H1 2017
Hemophilia B - Pipeline by Pfizer Inc, H1 2017
Hemophilia B - Pipeline by Pharming Group NV, H1 2017
Hemophilia B - Pipeline by Promethera Biosciences SA, H1 2017
Hemophilia B - Pipeline by RegenxBio Inc, H1 2017
Hemophilia B - Pipeline by rEVO Biologics Inc, H1 2017
Hemophilia B - Pipeline by Sangamo Therapeutics Inc, H1 2017
Hemophilia B - Pipeline by Shire Plc, H1 2017
Hemophilia B - Pipeline by Spark Therapeutics Inc, H1 2017
Hemophilia B - Pipeline by UniQure NV, H1 2017
Hemophilia B - Dormant Projects, H1 2017
Hemophilia B - Discontinued Products, H1 2017