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Published: Sep, 2014 | Pages:
79 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Hairy Cell Leukemia - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Hairy Cell Leukemia - Pipeline Review, H2 2014', provides an overview of the Hairy Cell Leukemia's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Hairy Cell Leukemia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Hairy Cell Leukemia and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Hairy Cell Leukemia - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Hairy Cell Leukemia and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Hairy Cell Leukemia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Hairy Cell Leukemia pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Hairy Cell Leukemia - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Hairy Cell Leukemia pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Hairy Cell Leukemia Overview 7 Therapeutics Development 8 Pipeline Products for Hairy Cell Leukemia - Overview 8 Pipeline Products for Hairy Cell Leukemia - Comparative Analysis 9 Hairy Cell Leukemia - Therapeutics under Development by Companies 10 Hairy Cell Leukemia - Pipeline Products Glance 12 Late Stage Products 12 Clinical Stage Products 13 Early Stage Products 14 Unknown Stage Products 15 Hairy Cell Leukemia - Products under Development by Companies 16 Hairy Cell Leukemia - Companies Involved in Therapeutics Development 17 Amgen Inc. 17 AstraZeneca PLC 18 GlaxoSmithKline plc 19 MedImmune, LLC 20 Plexxikon Inc. 21 Astellas Pharma Inc. 22 Incyte Corporation 23 Stemline Therapeutics, Inc. 24 Onconova Therapeutics, Inc. 25 Inbiopro Solutions Pvt. Ltd. 26 Biogenomics Limited 27 Hairy Cell Leukemia - Therapeutics Assessment 28 Assessment by Monotherapy Products 28 Assessment by Combination Products 29 Assessment by Target 30 Assessment by Mechanism of Action 33 Assessment by Route of Administration 36 Assessment by Molecule Type 38 Drug Profiles 40 moxetumomab pasudotox - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 (dabrafenib mesylate + trametinib dimethyl sulfoxide) - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 SL-401 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 PLX-8394 - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 rigosertib sodium - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 INCB-40093 - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 AZD-6738 - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 AGS-67E - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 INCB-40093 + INCB-39110 - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 interferon alfa-2b - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 blinatumomab - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 IBPB-006IA - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 interferon alfa-2a - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 Hairy Cell Leukemia - Recent Pipeline Updates 62 Hairy Cell Leukemia - Discontinued Products 76 Hairy Cell Leukemia - Product Development Milestones 77 Featured News & Press Releases 77 May 16, 2013: AstraZeneca's MedImmune Enrolls First Patient In Phase III Leukemia Trial Of Moxetumomab Pasudotox 77 Appendix 78 Methodology 78 Coverage 78 Secondary Research 78 Primary Research 78 Expert Panel Validation 78 Contact Us 79 Disclaimer 79
List of Tables Number of Products under Development for Hairy Cell Leukemia, H2 2014 8 Number of Products under Development for Hairy Cell Leukemia - Comparative Analysis, H2 2014 9 Number of Products under Development by Companies, H2 2014 11 Comparative Analysis by Late Stage Development, H2 2014 12 Comparative Analysis by Clinical Stage Development, H2 2014 13 Comparative Analysis by Early Stage Development, H2 2014 14 Comparative Analysis by Unknown Stage Development, H2 2014 15 Products under Development by Companies, H2 2014 16 Hairy Cell Leukemia - Pipeline by Amgen Inc., H2 2014 17 Hairy Cell Leukemia - Pipeline by AstraZeneca PLC, H2 2014 18 Hairy Cell Leukemia - Pipeline by GlaxoSmithKline plc, H2 2014 19 Hairy Cell Leukemia - Pipeline by MedImmune, LLC, H2 2014 20 Hairy Cell Leukemia - Pipeline by Plexxikon Inc., H2 2014 21 Hairy Cell Leukemia - Pipeline by Astellas Pharma Inc., H2 2014 22 Hairy Cell Leukemia - Pipeline by Incyte Corporation, H2 2014 23 Hairy Cell Leukemia - Pipeline by Stemline Therapeutics, Inc., H2 2014 24 Hairy Cell Leukemia - Pipeline by Onconova Therapeutics, Inc., H2 2014 25 Hairy Cell Leukemia - Pipeline by Inbiopro Solutions Pvt. Ltd., H2 2014 26 Hairy Cell Leukemia - Pipeline by Biogenomics Limited, H2 2014 27 Assessment by Monotherapy Products, H2 2014 28 Assessment by Combination Products, H2 2014 29 Number of Products by Stage and Target, H2 2014 32 Number of Products by Stage and Mechanism of Action, H2 2014 35 Number of Products by Stage and Route of Administration, H2 2014 37 Number of Products by Stage and Molecule Type, H2 2014 39 Hairy Cell Leukemia Therapeutics - Recent Pipeline Updates, H2 2014 62 Hairy Cell Leukemia - Discontinued Products, H2 2014 76
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