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Published: May, 2014 | Pages:
140 | Publisher: Global Markets Direct
Industry: Pharmaceutical | Report Format: Electronic (PDF)
Gilead Sciences, Inc. - Product Pipeline Review - 2014 Summary Global Markets Direct's, 'Gilead Sciences, Inc. - Product Pipeline Review - 2014', provides an overview of the Gilead Sciences, Inc.'s pharmaceutical research and development focus. This report provides comprehensive information on the current therapeutic developmental pipeline of Gilead Sciences, Inc.'s, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides brief overview of Gilead Sciences, Inc. including business description, key information and facts, and its locations and subsidiaries - The report reviews current pipeline of Gilead Sciences, Inc.'s human therapeutic division and enlists all their major and minor projects - The report features product description and descriptive mechanism of action for key pipeline products along with the product's developmental history and major milestones - Special feature on out-licensed and partnered product portfolio - The report summarizes all the dormant and discontinued pipeline projects - Latest company statement - Latest news and deals relating to the Gilead Sciences, Inc.'s pipeline products Reasons to buy - Evaluate Gilead Sciences, Inc.'s strategic position with total access to detailed information on its product pipeline - Assess the growth potential of Gilead Sciences, Inc. in its therapy areas of focus - Identify new drug targets and therapeutic classes in the Gilead Sciences, Inc.'s R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas - Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps - Develop strategic initiatives by understanding the focus areas of Gilead Sciences, Inc. and exploit collaboration and partnership opportunities - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Plan mergers and acquisitions effectively by identifying the most promising pipeline of Gilead Sciences, Inc. - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Explore the dormant and discontinued projects of Gilead Sciences, Inc. and identify potential opportunities in those areas - Avoid Intellectual Property Rights related issues
Table of Contents Table of Contents 2 List of Tables 7 List of Figures 7 Gilead Sciences, Inc. Snapshot 8 Gilead Sciences, Inc. Overview 8 Key Information 8 Key Facts 8 Gilead Sciences, Inc. - Research and Development Overview 9 Key Therapeutic Areas 9 Gilead Sciences, Inc. - Pipeline Review 14 Pipeline Products by Stage of Development 14 Pipeline Products - Monotherapy 15 Pipeline Products - Combination Treatment Modalities 16 Pipeline Products - Partnered Products 17 Partnered Products/Combination Treatment Modalities 18 Pipeline Products - Out-Licensed Products 19 Out-Licensed Products/Combination Treatment Modalities 20 Gilead Sciences, Inc. - Pipeline Products Glance 21 Gilead Sciences, Inc. - Late Stage Pipeline Products 21 Pre-Registration Products/Combination Treatment Modalities 21 Phase III Products/Combination Treatment Modalities 22 Gilead Sciences, Inc. - Clinical Stage Pipeline Products 23 Phase II Products/Combination Treatment Modalities 23 Phase I Products/Combination Treatment Modalities 25 Gilead Sciences, Inc. - Early Stage Pipeline Products 26 Preclinical Products/Combination Treatment Modalities 26 Discovery Products/Combination Treatment Modalities 27 Gilead Sciences, Inc. - Drug Profiles 28 (cobicistat + darunavir) 28 Product Description 28 Mechanism of Action 28 R&D Progress 28 (ledipasvir + sofosbuvir) 29 Product Description 29 Mechanism of Action 29 R&D Progress 29 cobicistat 31 Product Description 31 Mechanism of Action 31 R&D Progress 31 elvitegravir 33 Product Description 33 Mechanism of Action 33 R&D Progress 33 idelalisib 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 sofosbuvir 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 tenofovir disoproxil fumarate 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 (elvitegravir + cobicistat + emtricitabine + tenofovir alafenamide) 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 ambrisentan 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 momelotinib 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 nimotuzumab 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 ranolazine ER 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 tenofovir alafenamide 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 (darunavir + cobicistat + emtricitabine + tenofovir alafenamide) 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 (ranolazine + dronedarone) 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 (Sofosbuvir + GS-5816) 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 GS-4774 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 GS-5806 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 GS-6615 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 GS-9256 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 GS-9669 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 GS-9973 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 regadenoson 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 simtuzumab 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 tegobuvir 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 vedroprevir 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 GS-4997 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 GS-5737 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 GS-5745 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 GS-9620 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 GS-9857 77 Product Description 77 Mechanism of Action 77 R&D Progress 77 AB-0045 78 Product Description 78 Mechanism of Action 78 R&D Progress 78 GS-607601 79 Product Description 79 Mechanism of Action 79 R&D Progress 79 GS-8374 80 Product Description 80 Mechanism of Action 80 R&D Progress 80 GS-967 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 GS-563253 82 Product Description 82 Mechanism of Action 82 R&D Progress 82 GS-599220 83 Product Description 83 Mechanism of Action 83 R&D Progress 83 Small Molecule to Inhibit NS4B Protein for HCV 84 Product Description 84 Mechanism of Action 84 R&D Progress 84 Small Molecules to Inhibit NS3 Protease for Hepatitis C 85 Product Description 85 Mechanism of Action 85 R&D Progress 85 Gilead Sciences, Inc. - Pipeline Analysis 86 Gilead Sciences, Inc. - Pipeline Products by Target 86 Gilead Sciences, Inc. - Pipeline Products by Route of Administration 88 Gilead Sciences, Inc. - Pipeline Products by Molecule Type 89 Gilead Sciences, Inc. - Pipeline Products by Mechanism of Action 90 Gilead Sciences, Inc. - Recent Pipeline Updates 92 Gilead Sciences, Inc. - Dormant Projects 123 Gilead Sciences, Inc. - Discontinued Pipeline Products 126 Discontinued Pipeline Product Profiles 126 adefovir dipivoxil 126 ambrisentan 126 aztreonam 127 cicletanine 127 clevudine 127 Darusentan 127 dexelvucitabine 127 emivirine 128 enoximone 128 fentanyl citrate 128 GS-9005 128 GS-9132 128 GS-9667 129 PSI-938 129 tesmilifene hydrochloride 129 Gilead Sciences, Inc. - Company Statement 130 Gilead Sciences, Inc. - Locations And Subsidiaries 134 Head Office 134 Other Locations & Subsidiaries 134 Appendix 139 Methodology 139 Coverage 139 Secondary Research 139 Primary Research 139 Expert Panel Validation 139 Contact Us 140 Disclaimer 140
List of Tables Gilead Sciences, Inc., Key Information 8 Gilead Sciences, Inc., Key Facts 8 Gilead Sciences, Inc. - Pipeline by Indication, 2014 11 Gilead Sciences, Inc. - Pipeline by Stage of Development, 2014 14 Gilead Sciences, Inc. - Monotherapy Products in Pipeline, 2014 15 Gilead Sciences, Inc. - Combination Treatment Modalities in Pipeline, 2014 16 Gilead Sciences, Inc. - Partnered Products in Pipeline, 2014 17 Gilead Sciences, Inc. - Partnered Products/ Combination Treatment Modalities, 2014 18 Gilead Sciences, Inc. - Out-Licensed Products in Pipeline, 2014 19 Gilead Sciences, Inc. - Out-Licensed Products/ Combination Treatment Modalities, 2014 20 Gilead Sciences, Inc. - Pre-Registration, 2014 21 Gilead Sciences, Inc. - Phase III, 2014 22 Gilead Sciences, Inc. - Phase II, 2014 23 Gilead Sciences, Inc. - Phase I, 2014 25 Gilead Sciences, Inc. - Preclinical, 2014 26 Gilead Sciences, Inc. - Discovery, 2014 27 Gilead Sciences, Inc. - Pipeline by Target, 2014 87 Gilead Sciences, Inc. - Pipeline by Route of Administration, 2014 88 Gilead Sciences, Inc. - Pipeline by Molecule Type, 2014 89 Gilead Sciences, Inc. - Pipeline Products by Mechanism of Action, 2014 91 Gilead Sciences, Inc. - Recent Pipeline Updates, 2014 92 Gilead Sciences, Inc. - Dormant Developmental Projects,2014 123 Gilead Sciences, Inc. - Discontinued Pipeline Products, 2014 126 Gilead Sciences, Inc., Other Locations 134 Gilead Sciences, Inc., Subsidiaries 135
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