Genome Editing Market Analysis By Technology (CRISPR, TALEN, ZFN), By Delivery Method (Ex-vivo, In-vivo), By Application (Animal/Plant Cell Editing), By Service (In-house, Outsourced), By End-use And Segment Forecasts, 2014 - 2025

Published: Feb, 2017 | Pages: 185 | Publisher: Grand View Research
Industry: Biotechnology | Report Format: Electronic (PDF)

The global genome editing market is anticipated to reach USD 8.1 billion by 2025, according to a new report by Grand View Research, Inc. Key drivers attributing to the expansion include early applications of DNA editing to therapeutics. Use of the technology for the disease eradication through direct correction of disturbances in normal physiology, engineering the immune response, and alteration of pathogen targets in the host is anticipated to drive the market with substantial opportunities.

The ability of genome editing therapies to offer a significant improvement over current treatment options is important in enabling editing technologies to capture significant revenue share. Improved efficacy, reduced side effects, and the potential for cure for specific diseases, can be attributed to induce growth in the coming years.

Moreover, technological advancements with respect to the development of novel vectors for delivery is anticipated to fuel growth in the coming years. Rising competition amongst the operating entities in order to gain the larger share of revenue is also responsible for the projected growth. These companies leverage industry collaborations for the acceleration of diversified product pipelines.

Further Key Findings from the Study Suggest:

• There has been great excitement surrounding the highly adaptable CRISPR technology.

• The increased ease of retargeting and the ability to multiplex goes a long way toward explaining the speed with which CRISPR-centric companies have sprung up.

• Ex-vivo mode of delivery accounted for the largest share of the revenue.

• Therapy through ex-vivo mode of delivery allow the control over the specific dosage of therapeutic molecules delivered to cells.

• Cell line engineering dominated with respect to revenue generation owing to the high utilization of technology in stem cell engineering.

• There is comparatively, higher adoption of the technology in the biotechnology and pharmaceutical organizations for the purpose of therapeutic development.

• Availability of other services such as gRNA library production and screening service along with editing is anticipated to propel growth in the outsourcing services.

• Asia Pacific is anticipated to witness fastest growth over the forecast period owing to rising penetration of technology in comparatively immature market.

• Key players contributing in this market are Thermo Fisher Scientific, Inc., Sangamo, Editas Medicine, Recombinetics, Inc, Sigma Aldrich Corporation, CRISPR THERAPEUTICS, Intellia Therapeutics, Inc., Caribou Biosciences, Inc.

• These participants are capitalizing on unique advantages offered by the nuclease technology, they are working on.

 Table of Contents

Chapter 1 Research Methodology
1.1 Information Procurement
1.2 Data Analysis

Chapter 2 Executive Summary

Chapter 3 Genome Editing Market Variables, Trends & Scope
3.1 Market Segmentation & Scope
3.1.1 Market Driver Analysis
3.1.1.1 Success in pre-clinical models drives demands for genome editing therapeutics
3.1.1.2 Rising competition amongst market participants for business development
3.1.1.3 Easy editing solutions for development of therapeutics for broad range of diseases
3.1.1.4 Increasing demand for synthetic genes and genetically modified organisms
3.1.1.5 Technological advancements in gene editing technologies
3.1.1.6 Rising adoption in agricultural biotechnology
3.1.2 Market Restraint Analysis
3.1.2.1 Challenges with respect to clinical translation
3.1.2.2 Regulatory, scientific, and ethical challenges pertaining to the use of gene modified products
3.1.2.3 Off-target effects of CRISPR technology
3.2 Penetration & Growth Prospect Mapping for Technology, 2015
3.3 Molecular scissors / genome editing -Swot Analysis, By Factor (Political & Legal, Economic And Technological)
3.4 Industry Analysis - Porter's
3.5 Molecular Scissors / Genome Editing Technologies: Pipeline Analysis
3.5.1 Sangamo
3.5.2 Cellectis
3.5.3 Calyxt
3.5.4 bluebird bio
3.5.5 Editas Medicine
3.5.6 Intellia Therapeutics, Inc.
3.5.7 CRISPR THERAPEUTICS
3.5.8 Precision Biosciences
3.5.9 Precision Biosciences (Non medical domain)
3.5.10 Caribou Biosciences
3.5.11 Cibus
3.5.12 Recombinetics, Inc
3.6 Intellectual Property
3.7 Regulatory Issues
3.7.1 Orphan diseases
3.7.2 Germline editing
3.7.3 Safety issues

Chapter 4 Genome Editing Market: Technology Estimates & Trend Analysis
4.1 Molecular Scissors/ Genome Editing Market: Technology Movement Analysis
4.2 Molecular Scissors / Genome Editing Technology Comparison
4.3 (CRISPR)/Cas9
4.3.1 Global (CRISPR)/Cas9 market, 2014 - 2025 (USD Million)
4.4 TALENs/MegaTALs
4.4.1 Global TALENs/MegaTALs market, 2014 - 2025 (USD Million)
4.5 ZFN
4.5.1 Global ZFN market, 2014 - 2025 (USD Million)
4.6 Other Technologies
4.6.1 Global other technologies market, 2014 - 2025 (USD Million)

Chapter 5 Genome Editing Market: Delivery Method Estimates & Trend Analysis
5.1 Molecular Scissors/ Genome Editing Market: Delivery Method Movement Analysis
5.1.1 Comparison of Delivery Methods
5.1.1.1 Viral delivery
5.1.1.1.1 AAV (Adeno Associated Virus).
5.1.1.1.2 IDLV (Integrase Deficient Lentivirus).
5.1.1.2 Non-viral delivery
5.1.1.2.1 Lipid Mediated
5.1.1.2.2 Electroporation
5.2 Ex-vivo
5.2.1 Global ex-vivo delivery market, 2014 - 2025 (USD Million)
5.3 In-vivo
5.3.1 Global in-vivo delivery market, 2014 - 2025 (USD Million)

Chapter 6 Genome Editing Market: Application Estimates & Trend Analysis
6.1 Molecular Scissors / Genome Editing Market: Application Movement Analysis
6.2 Cell Line Engineering
6.2.1 Global cell line engineering market, 2014 - 2025 (USD Million)
6.3 Animal Genetic Engineering
6.3.1 Global animal genetic engineering market, 2014 - 2025 (USD Million)
6.4 Plant Genetic Engineering
6.4.1 Global plant genetic engineering market, 2014 - 2025 (USD Million)
6.5 Others
6.5.1 Global other applications market, 2014 - 2025 (USD Million)

Chapter 7 Genome Editing Market: End-use Estimates & Trend Analysis
7.1 Molecular Scissors / Genome Editing Market: End-use Movement Analysis
7.2 Biotechnology & Pharmaceutical Companies
7.2.1 Global biotechnology & pharmaceutical companies market, 2014 - 2025 (USD Million)
7.3 Academic & Government Research Institutes
7.3.1 Global academic & government research institutes market, 2014 - 2025 (USD Million)
7.4 Contract Research Organizations (CROs)
7.4.1 Global CROs market, 2014 - 2025 (USD Million)

Chapter 8 Genome Editing Market: Service Estimates & Trend Analysis
8.1 Molecular scissors / genome editing Market: Service Movement Analysis
8.2 In-house
8.2.1 Global in-house gene editing market, 2014 - 2025 (USD Million)
8.3 Contract
8.3.1 Global contract gene editing services market, 2014 - 2025 (USD Million)

Chapter 9 Genome Editing Market: Regional Estimates & Trend Analysis, by Technology, Delivery Method, Application, End-use, & Service
9.1 Molecular Scissors / Genome Editing Market Share By Region, 2015 & 2025
9.2 North America
9.2.1 North America molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.2.2 U.S.
9.2.2.1 U.S molecular scissors / genome editing culture market, 2014 - 2025 (USD Million)
9.2.3 Canada
9.2.3.1 Canada molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.3 Europe
9.3.1 Europe molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.3.2 Germany
9.3.2.1 Germany molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.3.3 UK
9.3.3.1 UK molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.4 Asia Pacific
9.4.1 Asia Pacific molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.4.2 Japan
9.4.2.1 Japan molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.4.3 China
9.4.3.1 China molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.5 Latin America
9.5.1 Latin America molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.5.2 Brazil
9.5.2.1 Brazil molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.6 Middle East & Africa
9.6.1 Middle East & Africa molecular scissors / genome editing market, 2014 - 2025 (USD Million)
9.6.2 South Africa
9.6.2.1 South Africa molecular scissors / genome editing market, 2014 - 2025 (USD Million)

Chapter 10 Competitive Landscape
10.1 Strategy Framework
10.1.1 Genome editing companies are developing products in a range of markets
10.1.2 Genome Editing Companies are targeting a variety of markets of various sizes
10.2 Market Participation Categorization
10.3 Company Profiles
10.3.1 Merck KGaA
10.3.1.1 Company overview
10.3.1.1.1 Sigma-Aldrich Co. LLC
10.3.1.2 Financial performance
10.3.1.2.1 Financial performance
10.3.1.3 Product benchmarking
10.3.1.4 Strategic initiatives
10.3.2 Cibus
10.3.2.1 Company overview
10.3.2.1.1 Nucelis
10.3.2.2 Financial performance
10.3.2.2.1 Financial performance
10.3.2.3 Product benchmarking
10.3.2.4 Strategic initiatives
10.3.3 Recombinetics, Inc
10.3.3.1 Company overview
10.3.3.2 Financial performance
10.3.3.3 Product benchmarking
10.3.3.4 Strategic initiatives
10.3.4 Sangamo
10.3.4.1 Company overview
10.3.4.2 Financial performance
10.3.4.3 Product benchmarking
10.3.4.4 Strategic initiatives
10.3.5 Editas Medicine
10.3.5.1 Company overview
10.3.5.2 Financial performance
10.3.5.3 Product benchmarking
10.3.5.4 Strategic initiatives
10.3.6 Precision Biosciences
10.3.6.1 Company overview
10.3.6.2 Financial performance
10.3.6.3 Product benchmarking
10.3.6.4 Strategic initiatives
10.3.7 CRISPR THERAPEUTICS
10.3.7.1 Company overview
10.3.7.2 Financial performance
10.3.7.3 Product benchmarking
10.3.7.4 Strategic initiatives
10.3.8 Intellia Therapeutics, Inc.
10.3.8.1 Company overview
10.3.8.2 Financial performance
10.3.8.3 Product benchmarking
10.3.8.4 Strategic initiatives
10.3.9 Caribou Biosciences, Inc
10.3.9.1 Company overview
10.3.9.2 Financial performance
10.3.9.3 Product benchmarking
10.3.9.4 Strategic initiatives
10.3.10 Cellectis
10.3.10.1 Company overview
10.3.10.1.1 Calyxt
10.3.10.2 Financial performance
10.3.10.2.1 Financial performance (Calyxt)
10.3.10.3 Product benchmarking
10.3.10.4 Strategic initiatives
10.3.11 AstraZeneca
10.3.11.1 Company overview
10.3.11.2 Financial performance
10.3.11.3 Product benchmarking
10.3.11.4 Strategic initiatives
10.3.12 Takara Bio USA
10.3.12.1 Company overview
10.3.12.2 Financial performance
10.3.12.3 Product benchmarking
10.3.12.4 Strategic initiatives
10.3.13 Horizon Discovery Group plc
10.3.13.1 Company overview
10.3.13.2 Financial performance
10.3.13.3 Product benchmarking
10.3.13.4 Strategic initiatives
10.3.14 Integrated DNA Technologies, Inc.
10.3.14.1 Company overview
10.3.14.2 Financial performance
10.3.14.3 Product benchmarking
10.3.15 Egenesis Inc.
10.3.15.1 Company overview
10.3.15.2 Financial performance
10.3.15.3 Product benchmarking
10.3.16 GenScript
10.3.16.1 Company overview
10.3.16.2 Financial performance
10.3.16.3 Product benchmarking
10.3.16.4 Strategic initiatives
10.3.17 New England Biolabs
10.3.17.1 Company overview
10.3.17.2 Financial performance
10.3.17.3 Product benchmarking
10.3.17.4 Strategic initiatives
10.3.18 OriGene Technologies, Inc.
10.3.18.1 Company overview
10.3.18.2 Financial performance
10.3.18.3 Product benchmarking
10.3.18.4 Strategic initiatives
10.3.19 bluebird bio, Inc.
10.3.19.1 Company overview
10.3.19.1.1 Precision Genome Engineering, Inc. (Pregenen)
10.3.19.2 Financial performance
10.3.19.2.1 Financial performance
10.3.19.3 Product benchmarking
10.3.19.4 Strategic initiatives
10.3.20 Lonza
10.3.20.1 Company overview
10.3.20.2 Financial performance
10.3.20.3 Product benchmarking
10.3.20.4 Strategic initiatives
10.3.21 Thermo Fisher Scientific, Inc.
10.3.21.1 Company overview
10.3.21.2 Financial performance
10.3.21.3 Product benchmarking
10.3.21.4 Strategic initiatives

List of Tables

TABLE 1 Molecular scissors / genome editing technology comparison
TABLE 2 North America molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 3 North America molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 4 North America molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 5 North America molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 6 North America molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 7 U.S. molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 8 U.S. molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 9 U.S. molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 10 U.S. molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 11 U.S. molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 12 Canada molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 13 Canada molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 14 Canada molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 15 Canada molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 16 Canada molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 17 Europe molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 18 Europe molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 19 Europe molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 20 Europe molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 21 Europe molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 22 Germany molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 23 Germany molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 24 Germany molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 25 Germany molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 26 Germany molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 27 UK molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 28 UK molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 29 UK molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 30 UK molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 31 UK molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 32 Asia Pacific molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 33 Asia Pacific molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 34 Asia Pacific molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 35 Asia Pacific molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 36 Asia Pacific molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 37 Japan molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 38 Japan molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 39 Japan molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 40 Japan molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 41 Japan molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 42 China molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 43 China molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 44 China molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 45 China molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 46 China molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 47 Latin America molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 48 Latin America molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 49 Latin America molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 50 Latin America molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 51 Latin America molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 52 Brazil molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 53 Brazil molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 54 Brazil molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 55 Brazil molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 56 Brazil molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 57 MEA molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 58 MEA molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 59 MEA molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 60 MEA molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 61 MEA molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)
TABLE 62 South Africa molecular scissors / genome editing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 63 South Africa molecular scissors / genome editing market estimates & forecasts, by delivery method, 2014 - 2025 (USD Million)
TABLE 64 South Africa molecular scissors / genome editing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 65 South Africa molecular scissors / genome editing market estimates & forecasts, by end-use, 2014 - 2025 (USD Million)
TABLE 66 South Africa molecular scissors / genome editing market estimates & forecasts, by service, 2014 - 2025 (USD Million)