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Published: Aug, 2014 | Pages:
95 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Diarrhea - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Diarrhea - Pipeline Review, H2 2014', provides an overview of the Diarrhea's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Diarrhea, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Diarrhea and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Diarrhea - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Diarrhea and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Diarrhea products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Diarrhea pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Diarrhea - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Diarrhea pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Diarrhea Overview 9 Therapeutics Development 10 Pipeline Products for Diarrhea - Overview 10 Pipeline Products for Diarrhea - Comparative Analysis 11 Diarrhea - Therapeutics under Development by Companies 12 Diarrhea - Therapeutics under Investigation by Universities/Institutes 14 Diarrhea - Pipeline Products Glance 15 Late Stage Products 15 Clinical Stage Products 16 Early Stage Products 17 Diarrhea - Products under Development by Companies 18 Diarrhea - Products under Investigation by Universities/Institutes 19 Diarrhea - Companies Involved in Therapeutics Development 20 Ipsen S.A. 20 Novartis AG 21 A. Menarini Industrie Farmaceutiche Riunite Srl 22 Mucosis B.V. 23 Helsinn Healthcare S.A. 24 Ventria Bioscience 25 Ache Laboratorios Farmaceuticos S/A 26 GP Pharm, S.A. 27 Syntiron LLC 28 Tioga Pharmaceuticals, Inc. 29 Intercept Pharmaceuticals, Inc. 30 Aegis Therapeutics, LLC 31 Drais Pharmaceuticals, Inc. 32 DiscoveryBiomed, Inc. 33 DesignMedix, Inc. 34 Chongqing Zhifei Biological Products Co., Ltd. 35 Sanofi Pasteur SA 36 Diarrhea - Therapeutics Assessment 37 Assessment by Monotherapy Products 37 Assessment by Target 38 Assessment by Mechanism of Action 40 Assessment by Route of Administration 43 Assessment by Molecule Type 45 Drug Profiles 47 ibodutant - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 asimadoline - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 talactoferrin alfa - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 lanreotide acetate - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 elsiglutide - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 obeticholic acid - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 ASP-7147 - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 iOWH0-32 - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 ETEC Adhesin-Based Vaccine - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 octreotide acetate MAR - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 ACH-04 - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 Diarrhea Vaccine - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 octreotide - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 INX-201 - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 Vaccine for Bacterial Diarrhea - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 UDCA Analogues for Diarrheal Diseases - Drug Profile 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 escherichia coli vaccine - Drug Profile 69 Product Description 69 Mechanism of Action 69 R&D Progress 69 yersinia pestis vaccine - Drug Profile 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 Small Molecule for Bacterial Infections - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 Small Molecule to Inhibit EnaC for Cystic Fibrosis, Diarrhea and Autosomal Dominant Polycystic Kidney Disease - Drug Profile 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 Small Molecules for Diarrhoea - Drug Profile 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 Small Molecules to Inhibit CFTR for Secretory Diarrhea - Drug Profile 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 Diarrhea - Recent Pipeline Updates 75 Diarrhea - Dormant Projects 84 Diarrhea - Discontinued Products 85 Diarrhea - Product Development Milestones 86 Featured News & Press Releases 86 Jul 01, 2014: Specialty Vaccine Company PaxVax Announces Positive Efficacy Results for Phase 3 Cholera Challenge Study 86 May 06, 2014: Intercept Reports Additional Positive OCA Data in Patients With Bile Acid Diarrhea at Digestive Disease Week 87 Feb 25, 2014: Salix Wins Napo Pharmaceuticals Litigation 88 Jan 14, 2014: Fulyzaq 125 mg Delayed-Release Tablets Significantly Improves Noninfectious Diarrhea in Adult Patients Living with HIV on ART Therapy 88 Oct 06, 2013: Ventria Bioscience to Present at the XIth International Conference on Lactoferrin 89 May 28, 2013: Helsinn And Zealand Pharma Announce Decision To Advance Development Of Elsiglutide Into Phase IIb For Prevention Of Chemotherapy-induced Diarrhea 90 May 28, 2013: Antidiarrheal drug candidate moves to next phase of clinical study 91 May 20, 2013: Intercept Pharma Announces Positive Initial Results From Ongoing Phase IIa Trial In Chronic Bile Acid Diarrhea 92 Nov 12, 2012: PATH's Drug Development Program Announces Positive Phase I Results For Anti-diarrheal Medication 92 Nov 12, 2012: Path Announces Positive Phase I Results Of iOWH032 To Treat Acute Secretory Diarrhea 93 Appendix 94 Methodology 94 Coverage 94 Secondary Research 94 Primary Research 94 Expert Panel Validation 94 Contact Us 95 Disclaimer 95
List of Tables Number of Products under Development for Diarrhea, H2 2014 10 Number of Products under Development for Diarrhea - Comparative Analysis, H2 2014 11 Number of Products under Development by Companies, H2 2014 13 Number of Products under Investigation by Universities/Institutes, H2 2014 14 Comparative Analysis by Late Stage Development, H2 2014 15 Comparative Analysis by Clinical Stage Development, H2 2014 16 Comparative Analysis by Early Stage Development, H2 2014 17 Products under Development by Companies, H2 2014 18 Products under Investigation by Universities/Institutes, H2 2014 19 Diarrhea - Pipeline by Ipsen S.A., H2 2014 20 Diarrhea - Pipeline by Novartis AG, H2 2014 21 Diarrhea - Pipeline by A. Menarini Industrie Farmaceutiche Riunite Srl, H2 2014 22 Diarrhea - Pipeline by Mucosis B.V., H2 2014 23 Diarrhea - Pipeline by Helsinn Healthcare S.A., H2 2014 24 Diarrhea - Pipeline by Ventria Bioscience, H2 2014 25 Diarrhea - Pipeline by Ache Laboratorios Farmaceuticos S/A, H2 2014 26 Diarrhea - Pipeline by GP Pharm, S.A., H2 2014 27 Diarrhea - Pipeline by Syntiron LLC, H2 2014 28 Diarrhea - Pipeline by Tioga Pharmaceuticals, Inc., H2 2014 29 Diarrhea - Pipeline by Intercept Pharmaceuticals, Inc., H2 2014 30 Diarrhea - Pipeline by Aegis Therapeutics, LLC, H2 2014 31 Diarrhea - Pipeline by Drais Pharmaceuticals, Inc., H2 2014 32 Diarrhea - Pipeline by DiscoveryBiomed, Inc., H2 2014 33 Diarrhea - Pipeline by DesignMedix, Inc., H2 2014 34 Diarrhea - Pipeline by Chongqing Zhifei Biological Products Co., Ltd., H2 2014 35 Diarrhea - Pipeline by Sanofi Pasteur SA, H2 2014 36 Assessment by Monotherapy Products, H2 2014 37 Number of Products by Stage and Target, H2 2014 39 Number of Products by Stage and Mechanism of Action, H2 2014 42 Number of Products by Stage and Route of Administration, H2 2014 44 Number of Products by Stage and Molecule Type, H2 2014 46 Diarrhea Therapeutics - Recent Pipeline Updates, H2 2014 75 Diarrhea - Dormant Projects, H2 2014 84 Diarrhea - Discontinued Products, H2 2014 85
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