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Published: Jul, 2014 | Pages:
59 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Diabetic Gastroparesis - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Diabetic Gastroparesis - Pipeline Review, H2 2014', provides an overview of the Diabetic Gastroparesis's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Diabetic Gastroparesis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Diabetic Gastroparesis and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Diabetic Gastroparesis - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Diabetic Gastroparesis and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Diabetic Gastroparesis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Diabetic Gastroparesis pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Diabetic Gastroparesis - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Diabetic Gastroparesis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Diabetic Gastroparesis Overview 6 Therapeutics Development 7 Pipeline Products for Diabetic Gastroparesis - Overview 7 Pipeline Products for Diabetic Gastroparesis - Comparative Analysis 8 Diabetic Gastroparesis - Therapeutics under Development by Companies 9 Diabetic Gastroparesis - Pipeline Products Glance 10 Late Stage Products 10 Clinical Stage Products 11 Early Stage Products 12 Diabetic Gastroparesis - Products under Development by Companies 13 Diabetic Gastroparesis - Companies Involved in Therapeutics Development 14 GlaxoSmithKline plc 14 Shire Plc 15 Evoke Pharma, Inc. 16 Targacept, Inc. 17 Cempra, Inc. 18 RaQualia Pharma Inc. 19 Rhythm Pharmaceuticals 20 Diabetic Gastroparesis - Therapeutics Assessment 21 Assessment by Monotherapy Products 21 Assessment by Target 22 Assessment by Mechanism of Action 24 Assessment by Route of Administration 26 Assessment by Molecule Type 28 Drug Profiles 30 metoclopramide hydrochloride - Drug Profile 30 Product Description 30 Mechanism of Action 30 R&D Progress 30 prucalopride succinate - Drug Profile 32 Product Description 32 Mechanism of Action 32 R&D Progress 32 camicinal - Drug Profile 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 relamorelin - Drug Profile 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 velusetrag - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 TC-6499 - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 RQ-00201894 - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 Small Molecules to Agonize Motilin Receptor for Gastric Disorders - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 Diabetic Gastroparesis - Recent Pipeline Updates 42 Diabetic Gastroparesis - Dormant Projects 49 Diabetic Gastroparesis - Discontinued Products 50 Diabetic Gastroparesis - Product Development Milestones 51 Featured News & Press Releases 51 Jun 25, 2014: Targacept Initiates Exploratory Study of TC-6499 in Diabetic Gastroparesis 51 May 28, 2014: Evoke Pharma Secures $4.5 Million Loan Facility With Square 1 Bank 51 May 06, 2014: Rhythm Presents Positive Phase 2 Study Results for Ghrelin Prokinetic Relamorelin (RM-131) in Diabetic Gastroparesis 52 Jan 22, 2014: Evoke Pharma Study Reports Positive Results of Metoclopramide Nasal Spray for Gastroparesis in Diabetics 53 Oct 15, 2013: Targacept Scientists to Present Data On TC-6499 at Society for Neuroscience Satellite Meeting 54 May 20, 2013: Rhythm Announces Phase Ib Results For Ghrelin Prokinetic RM-131 For Gastroparesis In Patients With Type 1 Diabetes 54 Oct 22, 2012: Rhythm Announces Positive Phase I Results For Ghrelin Prokinetic RM-131 For Treatment Of Diabetic Gastroparesis 55 Jun 06, 2012: Rhythm Initiates Phase II Clinical Trial Of Ghrelin Prokinetic RM-131 For Diabetic Gastroparesis 56 May 22, 2012: Rhythm Announces Phase Ib Results Of RM-131 For Diabetic Gastroparesis 56 May 09, 2011: Rhythm's RM-131 Restores Gastrointestinal Function As Potent Ghrelin Prokinetic 57 Appendix 58 Methodology 58 Coverage 58 Secondary Research 58 Primary Research 58 Expert Panel Validation 58 Contact Us 59 Disclaimer 59
List of Tables Number of Products under Development for Diabetic Gastroparesis, H2 2014 7 Number of Products under Development for Diabetic Gastroparesis - Comparative Analysis, H2 2014 8 Number of Products under Development by Companies, H2 2014 9 Comparative Analysis by Late Stage Development, H2 2014 10 Comparative Analysis by Clinical Stage Development, H2 2014 11 Comparative Analysis by Early Stage Development, H2 2014 12 Products under Development by Companies, H2 2014 13 Diabetic Gastroparesis - Pipeline by GlaxoSmithKline plc, H2 2014 14 Diabetic Gastroparesis - Pipeline by Shire Plc., H2 2014 15 Diabetic Gastroparesis - Pipeline by Evoke Pharma, Inc., H2 2014 16 Diabetic Gastroparesis - Pipeline by Targacept, Inc., H2 2014 17 Diabetic Gastroparesis - Pipeline by Cempra, Inc., H2 2014 18 Diabetic Gastroparesis - Pipeline by RaQualia Pharma Inc., H2 2014 19 Diabetic Gastroparesis - Pipeline by Rhythm Pharmaceuticals, H2 2014 20 Assessment by Monotherapy Products, H2 2014 21 Number of Products by Stage and Target, H2 2014 23 Number of Products by Stage and Mechanism of Action, H2 2014 25 Number of Products by Stage and Route of Administration, H2 2014 27 Number of Products by Stage and Molecule Type, H2 2014 29 Diabetic Gastroparesis Therapeutics - Recent Pipeline Updates, H2 2014 42 Diabetic Gastroparesis - Dormant Projects, H2 2014 49 Diabetic Gastroparesis - Discontinued Products, H2 2014 50
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