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Published: Sep, 2014 | Pages:
129 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Diabetic Foot Ulcers - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Diabetic Foot Ulcers - Pipeline Review, H2 2014', provides an overview of the Diabetic Foot Ulcers's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Diabetic Foot Ulcers, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Diabetic Foot Ulcers and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Diabetic Foot Ulcers - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Diabetic Foot Ulcers and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Diabetic Foot Ulcers products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Diabetic Foot Ulcers pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Diabetic Foot Ulcers - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Diabetic Foot Ulcers pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 7 List of Figures 8 Introduction 9 Global Markets Direct Report Coverage 9 Diabetic Foot Ulcers Overview 10 Therapeutics Development 11 Pipeline Products for Diabetic Foot Ulcers - Overview 11 Pipeline Products for Diabetic Foot Ulcers - Comparative Analysis 12 Diabetic Foot Ulcers - Therapeutics under Development by Companies 13 Diabetic Foot Ulcers - Pipeline Products Glance 16 Late Stage Products 16 Clinical Stage Products 17 Early Stage Products 18 Unknown Stage Products 19 Diabetic Foot Ulcers - Products under Development by Companies 20 Diabetic Foot Ulcers - Companies Involved in Therapeutics Development 22 Derma Sciences, Inc. 22 GlaxoSmithKline plc 23 CardioVascular BioTherapeutics, Inc. 24 Stratatech Corporation 25 Tissue Med Biosciences 26 Reliance Life Sciences Pvt. Ltd. 27 Celgene Corporation 28 Kaken Pharmaceutical Co., Ltd. 29 CytoTools AG 30 NovaLead Pharma Pvt. Ltd. 31 FirstString Research, Inc. 32 Lumosa Therapeutics Co., Ltd. 33 CoDa Therapeutics, Inc. 34 Adocia 35 Plurogen Therapeutics, Inc. 36 EyeGene, Inc. 37 Izun Pharmaceuticals Corporation 38 MacroCure 39 Royer Biomedical, Inc. 40 Oneness Biotech Co., Ltd. 41 Aprogen, Inc. 42 Pergamum AB 43 Dipexium Pharmaceuticals LLC 44 Kasiak Research Pvt. Ltd. 45 Innovaxis 46 Grupo Praxis Pharmaceutical SA 47 Diabetic Foot Ulcers - Therapeutics Assessment 48 Assessment by Monotherapy Products 48 Assessment by Target 49 Assessment by Mechanism of Action 52 Assessment by Route of Administration 55 Assessment by Molecule Type 57 Drug Profiles 60 pexiganan acetate - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 DermaPro - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 trafermin - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 Recombinant Protein to Agonize Platelet Derived Growth Factor Receptor for Metabolic and Dermatology Diseases - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 ON-101 - Drug Profile 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 DSC-127 - Drug Profile 69 Product Description 69 Mechanism of Action 69 R&D Progress 69 CureXcell - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 Granexin - Drug Profile 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 Vivefoot - Drug Profile 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 ReliDerm-DT - Drug Profile 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 CVBT-141B - Drug Profile 76 Product Description 76 Mechanism of Action 76 R&D Progress 76 CODA-001 - Drug Profile 78 Product Description 78 Mechanism of Action 78 R&D Progress 78 PX-070101 - Drug Profile 80 Product Description 80 Mechanism of Action 80 R&D Progress 80 IZN-6D4 - Drug Profile 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 CSTC-1 - Drug Profile 82 Product Description 82 Mechanism of Action 82 R&D Progress 82 PluroGel N - Drug Profile 83 Product Description 83 Mechanism of Action 83 R&D Progress 83 esmolol hydrochloride - Drug Profile 84 Product Description 84 Mechanism of Action 84 R&D Progress 84 gentamicin sulfate - Drug Profile 85 Product Description 85 Mechanism of Action 85 R&D Progress 85 GSK-1278863 - Drug Profile 86 Product Description 86 Mechanism of Action 86 R&D Progress 86 PDA-002 - Drug Profile 88 Product Description 88 Mechanism of Action 88 R&D Progress 88 TMBP-3 - Drug Profile 89 Product Description 89 Mechanism of Action 89 R&D Progress 89 coagulation factor XIVa (human) - Drug Profile 90 Product Description 90 Mechanism of Action 90 R&D Progress 90 AP-102 - Drug Profile 91 Product Description 91 Mechanism of Action 91 R&D Progress 91 Cyndacel-M - Drug Profile 92 Product Description 92 Mechanism of Action 92 R&D Progress 92 EG-Decorin - Drug Profile 93 Product Description 93 Mechanism of Action 93 R&D Progress 93 STD-06 - Drug Profile 94 Product Description 94 Mechanism of Action 94 R&D Progress 94 Nu-2 - Drug Profile 95 Product Description 95 Mechanism of Action 95 R&D Progress 95 Nu-3 - Drug Profile 96 Product Description 96 Mechanism of Action 96 R&D Progress 96 MT-003 - Drug Profile 97 Product Description 97 Mechanism of Action 97 R&D Progress 97 Cell Therapy to Activate VEGF for Venous Leg Ulcers and Diabetic Foot Ulcers - Drug Profile 98 Product Description 98 Mechanism of Action 98 R&D Progress 98 Gene Therapy to Activate HIF-1 Alpha for Wound and Ulcers - Drug Profile 99 Product Description 99 Mechanism of Action 99 R&D Progress 99 Cathelicidin - Drug Profile 100 Product Description 100 Mechanism of Action 100 R&D Progress 100 IMSP-001 - Drug Profile 102 Product Description 102 Mechanism of Action 102 R&D Progress 102 Drug for Diabetic Foot Ulcer - Drug Profile 103 Product Description 103 Mechanism of Action 103 R&D Progress 103 Synthetic Peptides to Antagonize TGF-Beta Receptor for Diabetic Foot Ulcers, Pulmonary Fibrosis and Dermatology - Drug Profile 104 Product Description 104 Mechanism of Action 104 R&D Progress 104 LL-37 - Drug Profile 106 Product Description 106 Mechanism of Action 106 R&D Progress 106 Refaheal - Drug Profile 107 Product Description 107 Mechanism of Action 107 R&D Progress 107 Diabetic Foot Ulcers - Recent Pipeline Updates 108 Diabetic Foot Ulcers - Dormant Projects 119 Diabetic Foot Ulcers - Discontinued Products 120 Diabetic Foot Ulcers - Product Development Milestones 121 Featured News & Press Releases 121 Sep 02, 2014: Macrocure Completes Enrollment in Pivotal Phase III Clinical Trial of CureXcell in Diabetic Foot Ulcers 121 Aug 25, 2014: Adocia Launches Phase III Clinical Study In India Of Treatment For Diabetic Foot Ulcer 121 Jul 25, 2014: Clinical development of wound healing drug DermaPro progressing on schedule in Europe 122 Jul 21, 2014: Dipexium Pharmaceuticals Initiates Second of Two Pivotal Phase 3 Clinical Trials of Locilex in Patients with Mild Infections of Diabetic Foot Ulcers 122 Jul 17, 2014: Dipexium Pharmaceuticals Announces Successful Completion of Phase 1 Skin Irritation Trial of Locilex 123 Jul 17, 2014: Dipexium Pharmaceuticals Initiates Pivotal Phase 3 Clinical Trial of Locilex in Patients with Mild Infections of Diabetic Foot Ulcers 124 May 21, 2014: MediWound Initiates Second Phase 2 Clinical Trial of EscharEx to Treat Chronic and Other Hard-to-Heal Wounds 125 Jan 16, 2014: Derma Sciences Provides Update on DSC127 Phase 3 Clinical Trials 125 Oct 10, 2013: Pergamum announces final data from Phase I/II study of LL-37 in patients with chronic leg ulcers 126 Sep 10, 2013: Dipexium Provides Locilex Manufacturing Update 127 Appendix 128 Methodology 128 Coverage 128 Secondary Research 128 Primary Research 128 Expert Panel Validation 128 Contact Us 129 Disclaimer 129
List of Tables Number of Products under Development for Diabetic Foot Ulcers, H2 2014 11 Number of Products under Development for Diabetic Foot Ulcers - Comparative Analysis, H2 2014 12 Number of Products under Development by Companies, H2 2014 14 Number of Products under Development by Companies, H2 2014 (Contd..1) 15 Comparative Analysis by Late Stage Development, H2 2014 16 Comparative Analysis by Clinical Stage Development, H2 2014 17 Comparative Analysis by Early Stage Development, H2 2014 18 Comparative Analysis by Unknown Stage Development, H2 2014 19 Products under Development by Companies, H2 2014 20 Products under Development by Companies, H2 2014 (Contd..1) 21 Diabetic Foot Ulcers - Pipeline by Derma Sciences, Inc., H2 2014 22 Diabetic Foot Ulcers - Pipeline by GlaxoSmithKline plc, H2 2014 23 Diabetic Foot Ulcers - Pipeline by CardioVascular BioTherapeutics, Inc., H2 2014 24 Diabetic Foot Ulcers - Pipeline by Stratatech Corporation, H2 2014 25 Diabetic Foot Ulcers - Pipeline by Tissue Med Biosciences, H2 2014 26 Diabetic Foot Ulcers - Pipeline by Reliance Life Sciences Pvt. Ltd., H2 2014 27 Diabetic Foot Ulcers - Pipeline by Celgene Corporation, H2 2014 28 Diabetic Foot Ulcers - Pipeline by Kaken Pharmaceutical Co., Ltd., H2 2014 29 Diabetic Foot Ulcers - Pipeline by CytoTools AG, H2 2014 30 Diabetic Foot Ulcers - Pipeline by NovaLead Pharma Pvt. Ltd., H2 2014 31 Diabetic Foot Ulcers - Pipeline by FirstString Research, Inc., H2 2014 32 Diabetic Foot Ulcers - Pipeline by Lumosa Therapeutics Co., Ltd., H2 2014 33 Diabetic Foot Ulcers - Pipeline by CoDa Therapeutics, Inc., H2 2014 34 Diabetic Foot Ulcers - Pipeline by Adocia, H2 2014 35 Diabetic Foot Ulcers - Pipeline by Plurogen Therapeutics, Inc., H2 2014 36 Diabetic Foot Ulcers - Pipeline by EyeGene, Inc., H2 2014 37 Diabetic Foot Ulcers - Pipeline by Izun Pharmaceuticals Corporation, H2 2014 38 Diabetic Foot Ulcers - Pipeline by MacroCure, H2 2014 39 Diabetic Foot Ulcers - Pipeline by Royer Biomedical, Inc. , H2 2014 40 Diabetic Foot Ulcers - Pipeline by Oneness Biotech Co., Ltd., H2 2014 41 Diabetic Foot Ulcers - Pipeline by Aprogen, Inc., H2 2014 42 Diabetic Foot Ulcers - Pipeline by Pergamum AB, H2 2014 43 Diabetic Foot Ulcers - Pipeline by Dipexium Pharmaceuticals LLC, H2 2014 44 Diabetic Foot Ulcers - Pipeline by Kasiak Research Pvt. Ltd., H2 2014 45 Diabetic Foot Ulcers - Pipeline by Innovaxis, H2 2014 46 Diabetic Foot Ulcers - Pipeline by Grupo Praxis Pharmaceutical SA, H2 2014 47 Assessment by Monotherapy Products, H2 2014 48 Number of Products by Stage and Target, H2 2014 51 Number of Products by Stage and Mechanism of Action, H2 2014 54 Number of Products by Stage and Route of Administration, H2 2014 56 Number of Products by Stage and Molecule Type, H2 2014 59 Diabetic Foot Ulcers Therapeutics - Recent Pipeline Updates, H2 2014 108 Diabetic Foot Ulcers - Dormant Projects, H2 2014 119 Diabetic Foot Ulcers - Discontinued Products, H2 2014 120
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