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Published: Oct, 2014 | Pages:
149 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Cutaneous T-Cell Lymphoma - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Cutaneous T-Cell Lymphoma - Pipeline Review, H2 2014', provides an overview of the Cutaneous T-Cell Lymphoma's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Cutaneous T-Cell Lymphoma, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Cutaneous T-Cell Lymphoma and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Cutaneous T-Cell Lymphoma - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Cutaneous T-Cell Lymphoma and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Cutaneous T-Cell Lymphoma products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Cutaneous T-Cell Lymphoma pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Cutaneous T-Cell Lymphoma - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Cutaneous T-Cell Lymphoma pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 7 Introduction 8 Global Markets Direct Report Coverage 8 Cutaneous T-Cell Lymphoma Overview 9 Therapeutics Development 10 Pipeline Products for Cutaneous T-Cell Lymphoma - Overview 10 Pipeline Products for Cutaneous T-Cell Lymphoma - Comparative Analysis 11 Cutaneous T-Cell Lymphoma - Therapeutics under Development by Companies 12 Cutaneous T-Cell Lymphoma - Therapeutics under Investigation by Universities/Institutes 14 Cutaneous T-Cell Lymphoma - Pipeline Products Glance 15 Late Stage Products 15 Clinical Stage Products 16 Early Stage Products 17 Cutaneous T-Cell Lymphoma - Products under Development by Companies 18 Cutaneous T-Cell Lymphoma - Products under Investigation by Universities/Institutes 19 Cutaneous T-Cell Lymphoma - Companies Involved in Therapeutics Development 20 Affimed Therapeutics AG 20 Chipscreen Biosciences Ltd 21 Cornerstone Pharmaceuticals, Inc. 22 Cyclacel Pharmaceuticals, Inc. 23 Eisai Co., Ltd. 24 Galderma S.A. 25 Innate Pharma SA 26 Johnson & Johnson 27 Kyowa Hakko Kirin Co., Ltd. 28 MedImmune, LLC 29 Neumedicines Inc. 30 Novartis AG 31 OncoSec Medical Inc. 32 Onyx Pharmaceuticals, Inc. 33 Seattle Genetics, Inc. 34 Soligenix, Inc. 35 TetraLogic Pharmaceuticals 36 Cutaneous T-Cell Lymphoma - Therapeutics Assessment 37 Assessment by Monotherapy Products 37 Assessment by Target 38 Assessment by Mechanism of Action 40 Assessment by Route of Administration 42 Assessment by Molecule Type 44 Drug Profiles 46 A-dmDT390-bisFv - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 AFM-13 - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 AMP-224 - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Angeloxin - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 bexarotene - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 brentuximab vedotin - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 carfilzomib - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 CPI-613 - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 Dendritic Cell Therapy for Immunology and Oncology - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 DNA IL-12 - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 everolimus - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 HBI-8000 - Drug Profile 72 Product Description 72 Mechanism of Action 72 R&D Progress 72 IPH-4102 - Drug Profile 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 mogamulizumab - Drug Profile 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 NMIL-121 - Drug Profile 77 Product Description 77 Mechanism of Action 77 R&D Progress 77 panobinostat - Drug Profile 79 Product Description 79 Mechanism of Action 79 R&D Progress 79 quisinostat - Drug Profile 85 Product Description 85 Mechanism of Action 85 R&D Progress 85 Recombinant Protein for CNS, Oncology, Hematological Disorders and Metabolic Disorders - Drug Profile 87 Product Description 87 Mechanism of Action 87 R&D Progress 87 sapacitabine - Drug Profile 88 Product Description 88 Mechanism of Action 88 R&D Progress 88 SGX-301 - Drug Profile 90 Product Description 90 Mechanism of Action 90 R&D Progress 90 SHP-141 - Drug Profile 92 Product Description 92 Mechanism of Action 92 R&D Progress 92 trifarotene - Drug Profile 94 Product Description 94 Mechanism of Action 94 R&D Progress 94 Cutaneous T-Cell Lymphoma - Recent Pipeline Updates 95 Cutaneous T-Cell Lymphoma - Dormant Projects 139 Cutaneous T-Cell Lymphoma - Discontinued Products 141 Cutaneous T-Cell Lymphoma - Product Development Milestones 142 Featured News & Press Releases 142 Sep 17, 2014: Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 142 Aug 27, 2014: Innate Pharma's IPH4102 Receives Orphan Drug Designation In European Union 142 Apr 07, 2014: OncoSec Medical To Relaunch Phase II Cutaneous T-Cell Lymphoma Study at Key Centers of Excellence 143 Mar 17, 2014: Approval for Additional Indication for PTCL and CTCL of Mogamulizumab 144 Jan 15, 2014: Addition of Japanese Sites for Pivotal Phase 3 Trial of Mogamulizumab in Patients with Cutaneous T-Cell Lymphoma 144 Oct 08, 2013: OncoSec Medical Announces Positive Preliminary Safety Data in Combination Study 144 Jul 19, 2013: Application Seeking Approval for Additional Indication for ATL, PTCL and CTCL of Mogamulizumab 145 Mar 04, 2013: Shape Pharma Provides Update On SHP-141 Topical HDAC Inhibitor Clinical Development For Cutaneous T Cell Lymphoma 146 Dec 13, 2012: Kyowa Hakko Kirin Initiates Pivotal Phase III Trial Of Mogamulizumab In Patients With Cutaneous T-Cell Lymphoma In US 146 Dec 11, 2012: Kyowa Hakko Kirin Announces Presentation Of Phase II Clinical Trial Results Of Mogamulizumab At ASH Annual Meeting 147 Appendix 148 Methodology 148 Coverage 148 Secondary Research 148 Primary Research 148 Expert Panel Validation 148 Contact Us 149 Disclaimer 149
List of Tables Number of Products under Development for Cutaneous T-Cell Lymphoma, H2 2014 10 Number of Products under Development for Cutaneous T-Cell Lymphoma - Comparative Analysis, H2 2014 11 Number of Products under Development by Companies, H2 2014 12 Number of Products under Investigation by Universities/Institutes, H2 2014 14 Comparative Analysis by Late Stage Development, H2 2014 15 Comparative Analysis by Clinical Stage Development, H2 2014 16 Comparative Analysis by Early Stage Development, H2 2014 17 Products under Development by Companies, H2 2014 18 Products under Investigation by Universities/Institutes, H2 2014 19 Cutaneous T-Cell Lymphoma - Pipeline by Affimed Therapeutics AG, H2 2014 20 Cutaneous T-Cell Lymphoma - Pipeline by Chipscreen Biosciences Ltd, H2 2014 21 Cutaneous T-Cell Lymphoma - Pipeline by Cornerstone Pharmaceuticals, Inc., H2 2014 22 Cutaneous T-Cell Lymphoma - Pipeline by Cyclacel Pharmaceuticals, Inc., H2 2014 23 Cutaneous T-Cell Lymphoma - Pipeline by Eisai Co., Ltd., H2 2014 24 Cutaneous T-Cell Lymphoma - Pipeline by Galderma S.A., H2 2014 25 Cutaneous T-Cell Lymphoma - Pipeline by Innate Pharma SA, H2 2014 26 Cutaneous T-Cell Lymphoma - Pipeline by Johnson & Johnson, H2 2014 27 Cutaneous T-Cell Lymphoma - Pipeline by Kyowa Hakko Kirin Co., Ltd., H2 2014 28 Cutaneous T-Cell Lymphoma - Pipeline by MedImmune, LLC, H2 2014 29 Cutaneous T-Cell Lymphoma - Pipeline by Neumedicines Inc., H2 2014 30 Cutaneous T-Cell Lymphoma - Pipeline by Novartis AG, H2 2014 31 Cutaneous T-Cell Lymphoma - Pipeline by OncoSec Medical Inc., H2 2014 32 Cutaneous T-Cell Lymphoma - Pipeline by Onyx Pharmaceuticals, Inc., H2 2014 33 Cutaneous T-Cell Lymphoma - Pipeline by Seattle Genetics, Inc., H2 2014 34 Cutaneous T-Cell Lymphoma - Pipeline by Soligenix, Inc., H2 2014 35 Cutaneous T-Cell Lymphoma - Pipeline by TetraLogic Pharmaceuticals, H2 2014 36 Assessment by Monotherapy Products, H2 2014 37 Number of Products by Stage and Target, H2 2014 39 Number of Products by Stage and Mechanism of Action, H2 2014 41 Number of Products by Stage and Route of Administration, H2 2014 43 Number of Products by Stage and Molecule Type, H2 2014 45 Cutaneous T-Cell Lymphoma Therapeutics - Recent Pipeline Updates, H2 2014 95 Cutaneous T-Cell Lymphoma - Dormant Projects, H2 2014 139 Cutaneous T-Cell Lymphoma - Dormant Projects (Contd..1), H2 2014 140 Cutaneous T-Cell Lymphoma - Discontinued Products, H2 2014 141
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