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Published: Jul, 2014 | Pages:
67 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Cirrhosis - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Cirrhosis - Pipeline Review, H2 2014', provides an overview of the Cirrhosis's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Cirrhosis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Cirrhosis and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Cirrhosis - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Cirrhosis and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Cirrhosis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Cirrhosis pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Cirrhosis - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Cirrhosis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Cirrhosis Overview 6 Therapeutics Development 7 Pipeline Products for Cirrhosis - Overview 7 Pipeline Products for Cirrhosis - Comparative Analysis 8 Cirrhosis - Therapeutics under Development by Companies 9 Cirrhosis - Therapeutics under Investigation by Universities/Institutes 10 Cirrhosis - Pipeline Products Glance 11 Clinical Stage Products 11 Early Stage Products 12 Cirrhosis - Products under Development by Companies 13 Cirrhosis - Products under Investigation by Universities/Institutes 14 Cirrhosis - Companies Involved in Therapeutics Development 15 Gilead Sciences, Inc. 15 Novartis AG 16 Ocera Therapeutics, Inc. 17 Hyperion Therapeutics, Inc. 18 Intercept Pharmaceuticals, Inc. 19 PharmaIN Corporation 20 Alfact Innovation 21 Cirrhosis - Therapeutics Assessment 22 Assessment by Monotherapy Products 22 Assessment by Target 23 Assessment by Mechanism of Action 25 Assessment by Route of Administration 27 Assessment by Molecule Type 29 Drug Profiles 31 ornithine phenylacetate - Drug Profile 31 Product Description 31 Mechanism of Action 31 R&D Progress 31 glycerol phenylbutyrate - Drug Profile 33 Product Description 33 Mechanism of Action 33 R&D Progress 33 obeticholic acid - Drug Profile 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 simtuzumab - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 Stem Cell Therapy for Gastrointestinal, CNS and Endocrine and Metabolic Disorders - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 erismodegib - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 ALF-5755 - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 PGC Based Natriuretic Peptides - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 Cirrhosis - Recent Pipeline Updates 48 Cirrhosis - Dormant Projects 60 Cirrhosis - Product Development Milestones 61 Featured News & Press Releases 61 Nov 01, 2013: Salix Pharmaceuticals Outlines Data Presentations at American Association for the Study of Liver Diseases Annual Meeting 61 Sep 19, 2013: Les Laboratoires Servier Receives CHMP Positive Opinion For Valdoxan 61 Sep 17, 2013: Vasopressin V2 Receptor Antagonist Samsca 7.5mg Tablets Granted Additional Indication in Japan for the Treatment of Fluid Retention in Patients with Hepatic Cirrhosis 62 May 02, 2013: Hyperion Therapeutics Receives Orphan Drug Exclusivity From FDA 62 Nov 12, 2012: Hyperion Therapeutics Announces Presentation Of Results From Phase II HALT-HE Study At 63rd Annual Meeting Of AASLD 62 Nov 09, 2012: Salix Pharma Announces Presentation Of Xifaxan Data At 63rd Annual Meeting Of AASLD 63 Nov 05, 2011: Janssen Presents New Data On INCIVO At American Association For Society Of Liver Disease Annual Meeting 64 Appendix 66 Methodology 66 Coverage 66 Secondary Research 66 Primary Research 66 Expert Panel Validation 66 Contact Us 67 Disclaimer 67
List of Tables Number of Products under Development for Cirrhosis, H2 2014 7 Number of Products under Development for Cirrhosis - Comparative Analysis, H2 2014 8 Number of Products under Development by Companies, H2 2014 9 Number of Products under Investigation by Universities/Institutes, H2 2014 10 Comparative Analysis by Clinical Stage Development, H2 2014 11 Comparative Analysis by Early Stage Development, H2 2014 12 Products under Development by Companies, H2 2014 13 Products under Investigation by Universities/Institutes, H2 2014 14 Cirrhosis - Pipeline by Gilead Sciences, Inc., H2 2014 15 Cirrhosis - Pipeline by Novartis AG, H2 2014 16 Cirrhosis - Pipeline by Ocera Therapeutics, Inc., H2 2014 17 Cirrhosis - Pipeline by Hyperion Therapeutics, Inc., H2 2014 18 Cirrhosis - Pipeline by Intercept Pharmaceuticals, Inc., H2 2014 19 Cirrhosis - Pipeline by PharmaIN Corporation, H2 2014 20 Cirrhosis - Pipeline by Alfact Innovation, H2 2014 21 Assessment by Monotherapy Products, H2 2014 22 Number of Products by Stage and Target, H2 2014 24 Number of Products by Stage and Mechanism of Action, H2 2014 26 Number of Products by Stage and Route of Administration, H2 2014 28 Number of Products by Stage and Molecule Type, H2 2014 30 Cirrhosis Therapeutics - Recent Pipeline Updates, H2 2014 48 Cirrhosis - Dormant Projects, H2 2014 60
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