Circulating Tumor Cells (CTC) Market Size, Share & Trends Analysis Report By By Technology (Detection, Enrichment), Application (Cancer Stem Cell Research, EMT Biomarkers Development), And Segment Forecasts, 2019 - 2025

Published: Apr, 2019 | Pages: 138 | Publisher: Grand View Research
Industry: Biotechnology | Report Format: Electronic (PDF)

The global circulating tumor cells market size is anticipated to reach USD 17.56 billion by 2025 growing at a CAGR of 15.0% during the forecast period, according to a new report by Grand View Research, Inc. Introduction of novel technologies for enumeration of CTC is anticipated to fuel the market growth. Rising cases of chronic oncology diseases that depend on CTC detection and analysis, as it has enormous potential in real-time monitoring of cancer therapy over methods like imaging technologies and tumor tissue biopsy, will also drive the market.

Additionally, application of CTC as biomarkers for drug discovery is a promising factor for growth in the coming years. Utilization of the CTCs in the development of tumor-specific biomarkers to optimize the selection of targeted therapies and assessment of better response to the therapy is expected to support in the market growth. CTC enrichment accounted for the largest revenue share of the global market in 2018 and is expected to continue the dominance throughout the forecast period. This is due to extensive usage in oncology research establishments and high accuracy exhibited by this technology.

Microchips technology is anticipated to register the highest CAGR owing to the introduction of cluster chip technology that helps capture the clusters of tumor cells for CTC quantitation. Cancer stem cell research segment accounts for the largest revenue share of the market. Properties of the cancer stem cells of self-renewal in replenishing the growing cancer is driving the attention of organizations and researchers in CTC cancer stem cell research segment.

Further key findings from the study suggest:

• Application of alterations in the expression profiles of EMT-associated transcriptional regulators and their molecular targets as biomarkers in EMT study is expected to serve as an impetus for diagnosis of tumor

• North America led the CTC market in 2018 due to rising cases of cancer, oncology research funding, and favorable government initiatives for clinical diagnostic products

• APAC is anticipated to witness the highest CAGR of over 16% from 2019 to 2025 due to infrastructural development in care centers and increased sales of CTC diagnostic tests

• Rising need for new diagnosis methods for cancer has encouraged R&D in developing economies of APAC. This will help expand the region further

• Fluxion Biosciences, Inc.; AdnaGen AG; Biocept, Inc.; Ikonisys, Inc.; and Sysmex Corp. are some of the key industry participants

• Key companies focus on the development of novel technologies for CTC enrichment & detection through collaborations with hospitals and university-based research institutes to gain access to target population

Table of Contents

Chapter 1. Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Market Definition
1.3. Information Procurement
1.3.1. Purchased database
1.3.2. GVR's internal database
1.3.3. Secondary sources & third party perspectives
1.3.4. Primary research
1.4. Information Analysis
1.4.1. Data analysis models
1.5. Market Formulation & Data Visualization
1.6. Data Validation & Publishing

Chapter 2. Executive Summary
2.1. CTC Market Outlook, 2014 - 2025
2.2. CTC Market Segment Outlook, 2014 - 2025
2.3. Competitive Insights

Chapter 3. CTC Market Variables, Trends & Scope
3.1. Market Lineage Outlook
3.1.1. Parent market outlook
3.1.2. Related/ancillary market outlook
3.2. Penetration & Growth Prospect Mapping
3.3. Product Pipeline Analysis, by Stage
3.4. User Perspective Analysis
3.4.1. Consumer behavior analysis
3.4.2. Market influencer analysis
3.4.3. Procedure cost analysis/breakdown
3.5. Technology Overview
3.5.1. Technology timeline
3.6. Regulatory Framework
3.6.1. Reimbursement framework
3.6.2. Standards & compliances
3.7. Market Dynamics
3.7.1. Market driver analysis
3.7.1.1. Development of cluster chip technology
3.7.1.2. Potential applications of CTC in cancer management
3.7.1.3. Medical need for cancer diagnostics
3.7.1.4. Rising demand for preventive medicine & companion diagnostics
3.7.1.5. Growing cancer incidence
3.7.2. Market restraint analysis
3.7.2.1. Rare occurrence of circulating tumor cells
3.7.2.2. Lack of consistency in detection and enrichment methods
3.7.2.3. Higher preference of point-of-care testing and absence of POC adaptable CTC
3.7.3. Industry challenges
3.7.3.1. High cost of diagnostics
3.8. CTC Market Analysis Tools
3.8.1. Industry analysis - Porter's
3.8.1.1. Supplier power: (moderate due to large number of players)
3.8.1.2. Buyer power: (moderately low due to limited number of tests for clinical use)
3.8.1.3. Substitution threat: (low due to product specificity)
3.8.1.4. Threat from new entrant: (low owing to the presence of stringent guidelines)
3.8.1.5. Competitive rivalry: (high)
3.8.2. PESTEL Analysis
3.8.2.1. Political landscape
3.8.2.2. Environmental landscape
3.8.2.3. Social landscape
3.8.2.4. Technology landscape
3.8.2.5. Legal landscape
3.8.3. Major Deals & Strategic Alliances Analysis
3.8.3.1. Joint ventures
3.8.3.2. Mergers & acquisitions
3.8.3.3. Licensing & partnership
3.8.3.4. Technology collaborations
3.8.3.5. Strategic divestments
3.8.4. Market entry strategies
3.8.5. Case studies

Chapter 4. CTC Market - Competitive Analysis
4.1. Recent Developments & Impact Analysis, by Key Market Participants
4.2. Company/Competition Categorization
4.3. Vendor Landscape
4.3.1. List of key distributors and channel partners
4.3.2. Key customers
4.3.3. Key company market share analysis, 2018
4.4. Public Companies
4.4.1. Company market position analysis
4.4.2. Company market share/ranking, by region
4.4.3. Competitive dashboard analysis
4.4.4. Market differentiators
4.4.5. Synergy analysis: major deals & strategic alliances
4.5. Private Companies
4.5.1. List of key emerging companies' products
4.5.2. Regional network map
4.5.3. Company market position analysis
4.5.4. Supplier ranking

Chapter 5. CTC Market: Technology Estimates & Trend Analysis
5.1. Definitions & Scope
5.2. Technology Market Share Analysis, 2018 & 2025
5.3. Segment Dashboard
5.4. Global CTC Market, by Technology, 2014 to 2025
5.5. Market Size & Forecasts and Trend Analyses, 2014 to 2025 for the following:
5.5.1. CTC enrichment methods market, 2014 to 2025
5.5.1.1. Market revenue (USD Million), by region
5.5.1.2. Ex vivo positive selection market, 2014 to 2025
5.5.1.2.1. Market revenue (USD Million), by region
5.5.1.3. In vivo positive selection market, 2014 to 2025
5.5.1.3.1. Market revenue (USD Million), by region
5.5.1.4. Negative selection market, 2014 to 2025
5.5.1.4.1. Market revenue (USD Million), by region
5.5.1.5. Microchips market, 2014 to 2025
5.5.1.5.1. Market revenue (USD Million), by region
5.5.1.6. Single spiral microchannel market, 2014 to 2025
5.5.1.6.1. Market revenue (USD Million), by region
5.5.2. CTC detection methods market, 2014 to 2025
5.5.2.1. Market revenue (USD Million), by region
5.5.2.2. Immunocytochemical technologies market, 2014 to 2025
5.5.2.2.1. Market revenue (USD Million), by region
5.5.2.3. Molecular (RNA) based technologies market, 2014 to 2025
5.5.2.3.1. Market revenue (USD Million), by region
5.5.2.4. Functional in vitro cell invasion assay market, 2014 to 2025
5.5.2.4.1. Market revenue (USD Million), by region
5.5.2.5. Xenotransplantation models market, 2014 to 2025
5.5.2.5.1. Market revenue (USD Million), by region
5.5.3. CTC analysis market, 2014 to 2025
5.5.3.1. Market revenue (USD Million), by region
5.6. CTC Technology Market, by Application, 2014 to 2025
5.6.1. Market revenue (USD Million), 2014 to 2025

Chapter 6. CTC Market: Application Estimates & Trend Analysis
6.1. Definitions & Scope
6.2. Application Market Share Analysis, 2018 & 2025
6.3. Segment Dashboard
6.4. Global CTC Market, by Application, 2014 to 2025
6.5. Market Size & Forecasts and Trend Analyses, 2014 to 2025 for the following:
6.5.1. Cancer stem cell research market, 2014 to 2025
6.5.1.1. Market revenue (USD Million), by region
6.5.2. EMT biomarkers development market, 2014 to 2025
6.5.2.1. Market revenue (USD Million), by region
6.5.3. Tumorgenesis research market, 2014 to 2025
6.5.3.1. Market revenue (USD Million), by region
6.5.4. Other applications market, 2014 to 2025
6.5.4.1. Market revenue (USD Million), by region

Chapter 7. CTC Market: Regional Estimates & Trend Analysis, by Technology and Application
7.1. CTC Market: Regional Snapshot
7.2. CTC Market: Regional Share and Leading Players, 2018
7.2.1. North America
7.2.2. Europe
7.2.3. Asia Pacific
7.2.4. Latin America
7.2.5. Middle East & Africa
7.3. North America
7.3.1. North America CTC market revenue (USD Million)
7.3.2. U.S. CTC market
7.3.2.1. U.S. CTC market, by technology
7.3.2.2. U.S. CTC market, by application
7.3.3. Canada CTC market
7.3.3.1. Canada CTC market, by gestation duration
7.3.3.2. Canada CTC market, by application
7.4. Europe
7.4.1. Europe CTC market revenue (USD Million)
7.4.2. U.K.
7.4.2.1. U.K. CTC market, by technology
7.4.2.2. U.K. CTC market, by application
7.4.3. Germany
7.4.3.1. Germany CTC market, by technology
7.4.3.2. Germany CTC market, by application
7.4.4. Spain
7.4.4.1. Spain CTC market, by technology
7.4.4.2. Spain CTC market, by application
7.4.5. France
7.4.5.1. France CTC market, by technology
7.4.5.2. France CTC market, by application
7.4.6. Italy
7.4.6.1. Italy CTC market, by technology
7.4.6.2. Italy CTC market, by application
7.4.7. Russia
7.4.7.1. Russia CTC market, by technology
7.4.7.2. Russia CTC market, by application
7.5. Asia Pacific
7.5.1. Asia Pacific CTC market revenue (USD Million)
7.5.2. China
7.5.2.1. China CTC market, by technology
7.5.2.2. China CTC market, by application
7.5.3. Japan
7.5.3.1. Japan CTC market, by technology
7.5.3.2. Japan CTC market, by application
7.5.4. India
7.5.4.1. India CTC market, by technology
7.5.4.2. India CTC market, by application
7.5.5. South Korea
7.5.5.1. South Korea CTC market, by technology
7.5.5.2. South Korea CTC market, by application
7.5.6. Singapore
7.5.6.1. Singapore CTC market, by technology
7.5.6.2. Singapore CTC market, by application
7.5.7. Australia
7.5.7.1. Australia CTC market, by technology
7.5.7.2. Australia CTC market, by application
7.6. Latin America
7.6.1. Latin America CTC market revenue (USD Million)
7.6.2. Brazil
7.6.2.1. Brazil CTC market, by technology
7.6.2.2. Brazil CTC market, by application
7.6.3. Argentina
7.6.3.1. Argentina CTC market, by technology
7.6.3.2. Argentina CTC market, by application
7.7. Middle East & Africa (MEA)
7.7.1. MEA CTC market revenue (USD Million)
7.7.2. South Africa
7.7.2.1. South Africa CTC market, by technology
7.7.2.2. South Africa CTC market, by application
7.7.3. UAE
7.7.3.1. UAE CTC market, by technology
7.7.3.2. UAE CTC market, by application
7.8. SWOT Analysis, by Factor (Political & Legal, Economic And Technological)
7.8.1. North America
7.8.2. Europe
7.8.3. Asia Pacific
7.8.4. Latin America
7.8.5. Middle East & Africa

Chapter 8. Company Profiles
8.1. Company Profiles
8.1.1. Adnagen AG
8.1.1.1. Company Overview
8.1.1.2. Financial Performance
8.1.1.3. Product Benchmarking
8.1.1.4. Strategic Initiatives
8.1.2. Advanced Cell Diagnostics
8.1.2.1. Company Overview
8.1.2.2. Financial Performance
8.1.2.3. Product Benchmarking
8.1.2.4. Strategic Initiatives
8.1.3. Apocell
8.1.3.1. Company Overview
8.1.3.2. Financial Performance
8.1.3.3. Product Benchmarking
8.1.3.4. Strategic Initiatives
8.1.4. Aviva Biosciences
8.1.4.1. Company Overview
8.1.4.2. Financial Performance
8.1.4.3. Product Benchmarking
8.1.4.4. Strategic Initiatives
8.1.5. Biocep Ltd.
8.1.5.1. Company Overview
8.1.5.2. Financial Performance
8.1.5.3. Product Benchmarking
8.1.5.4. Strategic Initiatives
8.1.6. Biocept Inc.
8.1.6.1. Company Overview
8.1.6.2. Financial Performance
8.1.6.3. Product Benchmarking
8.1.6.4. Strategic Initiatives
8.1.7. Biofluidica
8.1.7.1. Company Overview
8.1.7.2. Financial Performance
8.1.7.3. Product Benchmarking
8.1.7.4. Strategic Initiatives
8.1.8. Canopus Biosciences
8.1.8.1. Company Overview
8.1.8.2. Financial Performance
8.1.8.3. Product Benchmarking
8.1.8.4. Strategic Initiatives
8.1.9. CellTraffix Inc.
8.1.9.1. Company Overview
8.1.9.2. Financial Performance
8.1.9.3. Product Benchmarking
8.1.9.4. Strategic Initiatives
8.1.10. Clearbridge BioMedics
8.1.10.1. Company Overview
8.1.10.2. Financial Performance
8.1.10.3. Product Benchmarking
8.1.10.4. Strategic Initiatives
8.1.11. Creatv Microtech Inc.
8.1.11.1. Company Overview
8.1.11.2. Financial Performance
8.1.11.3. Product Benchmarking
8.1.11.4. Strategic Initiatives
8.1.12. Cynvenio Biosystems Inc.
8.1.12.1. Company Overview
8.1.12.2. Financial Performance
8.1.12.3. Product Benchmarking
8.1.12.4. Strategic Initiatives
8.1.13. Epic Biosciences
8.1.13.1. Company Overview
8.1.13.2. Financial Performance
8.1.13.3. Product Benchmarking
8.1.13.4. Strategic Initiatives
8.1.14. Fluxion Biosciences
8.1.14.1. Company Overview
8.1.14.2. Financial Performance
8.1.14.3. Product Benchmarking
8.1.14.4. Strategic Initiatives
8.1.15. Greiner Bio-One GmbH
8.1.15.1. Company Overview
8.1.15.2. Financial Performance
8.1.15.3. Product Benchmarking
8.1.15.4. Strategic Initiatives
8.1.16. Ikonisys Inc.
8.1.16.1. Company Overview
8.1.16.2. Financial Performance
8.1.16.3. Product Benchmarking
8.1.16.4. Strategic Initiatives
8.1.17. IV Diagnostics Inc.
8.1.17.1. Company Overview
8.1.17.2. Financial Performance
8.1.17.3. Product Benchmarking
8.1.17.4. Strategic Initiatives
8.1.18. Janssen Diagnostics
8.1.18.1. Company Overview
8.1.18.2. Financial Performance
8.1.18.3. Product Benchmarking
8.1.18.4. Strategic Initiatives
8.1.19. Miltenyi Biotech
8.1.19.1. Company Overview
8.1.19.2. Financial Performance
8.1.19.3. Product Benchmarking
8.1.19.4. Strategic Initiatives
8.1.20. Nanostring Technologies Inc.
8.1.20.1. Company Overview
8.1.20.2. Financial Performance
8.1.20.3. Product Benchmarking
8.1.20.4. Strategic Initiatives
8.1.21. Rarecells
8.1.21.1. Company Overview
8.1.21.2. Financial Performance
8.1.21.3. Product Benchmarking
8.1.21.4. Strategic Initiatives
8.1.22. ScreenCell
8.1.22.1. Company Overview
8.1.22.2. Financial Performance
8.1.22.3. Product Benchmarking
8.1.22.4. Strategic Initiatives
8.1.23. Silicon Biosystems USA
8.1.23.1. Company Overview
8.1.23.2. Financial Performance
8.1.23.3. Product Benchmarking
8.1.23.4. Strategic Initiatives
8.1.24. Stem Cell Technologies
8.1.24.1. Company Overview
8.1.24.2. Financial Performance
8.1.24.3. Product Benchmarking
8.1.24.4. Strategic Initiatives
8.1.25. Sysmex Corporation
8.1.25.1. Company Overview
8.1.25.2. Financial Performance
8.1.25.3. Product Benchmarking
8.1.25.4. Strategic Initiatives
8.1.26. Vitatex Inc
8.1.26.1. Company Overview
8.1.26.2. Financial Performance
8.1.26.3. Product Benchmarking
8.1.26.4. Strategic Initiatives
8.2. List of companies

List of Tables

1. CTC market - Industry Snapshot & Key Buying Criteria, 2014 - 2025
2. Global CTC market, by technology, 2014 - 2025 (USD Million)
3. Global CTC market, by application, 2014 - 2025 (USD Million)
4. Global CTC market, by region, 2014 - 2025 (USD Million)
5. CTC- Key market driver analysis
6. CTC- Key market restraint analysis
7. North America CTC market, by technology, 2014 - 2025 (USD Million)
8. North America CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
9. North America CTC detection methods market, by technology, 2014 - 2025 (USD Million)
10. North America CTC market, by application, 2014 - 2025 (USD Million)
11. U.S. CTC market, by technology, 2014 - 2025 (USD Million)
12. U.S. CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
13. U.S. CTC detection methods market, by technology, 2014 - 2025 (USD Million)
14. U.S. CTC market, by application, 2014 - 2025 (USD Million)
15. Canada CTC market, by technology, 2014 - 2025 (USD Million)
16. Canada CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
17. Canada CTC detection methods market, by technology, 2014 - 2025 (USD Million)
18. Canada CTC market, by application, 2014 - 2025 (USD Million)
19. Europe CTC market, by technology, 2014 - 2025 (USD Million)
20. Europe CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
21. Europe CTC detection methods market, by technology, 2014 - 2025 (USD Million)
22. Europe CTC market, by application, 2014 - 2025 (USD Million)
23. Germany CTC market, by technology, 2014 - 2025 (USD Million)
24. Germany CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
25. Germany CTC detection methods market, by technology, 2014 - 2025 (USD Million)
26. Germany CTC market, by application, 2014 - 2025 (USD Million)
27. U.K. CTC market, by technology, 2014 - 2025 (USD Million)
28. U.K. CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
29. U.K. CTC detection methods market, by technology, 2014 - 2025 (USD Million)
30. U.K. CTC market, by application, 2014 - 2025 (USD Million)
31. France CTC market, by technology, 2014 - 2025 (USD Million)
32. France CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
33. France CTC detection methods market, by technology, 2014 - 2025 (USD Million)
34. France CTC market, by application, 2014 - 2025 (USD Million)
35. Asia Pacific CTC market, by technology, 2014 - 2025 (USD Million)
36. Asia Pacific CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
37. Asia Pacific CTC detection methods market, by technology, 2014 - 2025 (USD Million)
38. Asia Pacific CTC market, by application, 2014 - 2025 (USD Million)
39. China CTC market, by technology, 2014 - 2025 (USD Million)
40. China CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
41. China CTC detection methods market, by technology, 2014 - 2025 (USD Million)
42. China CTC market, by application, 2014 - 2025 (USD Million)
43. Japan CTC market, by technology, 2014 - 2025 (USD Million)
44. Japan CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
45. Japan CTC detection methods market, by technology, 2014 - 2025 (USD Million)
46. Japan CTC market, by application, 2014 - 2025 (USD Million)
47. Latin America CTC market, by technology, 2014 - 2025 (USD Million)
48. Latin America CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
49. Latin America CTC detection methods market, by technology, 2014 - 2025 (USD Million)
50. Latin America CTC market, by application, 2014 - 2025 (USD Million)
51. Brazil CTC market, by technology, 2014 - 2025 (USD Million)
52. Brazil CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
53. Brazil CTC detection methods market, by technology, 2014 - 2025 (USD Million)
54. Brazil CTC market, by application, 2014 - 2025 (USD Million)
55. MEA CTC market, by technology, 2014 - 2025 (USD Million)
56. MEA CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
57. MEA CTC detection methods market, by technology, 2014 - 2025 (USD Million)
58. MEA CTC market, by application, 2014 - 2025 (USD Million)
59. South Africa CTC market, by technology, 2014 - 2025 (USD Million)
60. South Africa CTC enrichment methods market, by technology, 2014 - 2025 (USD Million)
61. South Africa CTC detection methods market, by technology, 2014 - 2025 (USD Million)
62. South Africa CTC market, by application, 2014 - 2025 (USD Million)

List of Figures

1. CTC market segmentation
2. Global CTC market, 2014 - 2025 (USD Million)
3. CTC market dynamics
4. CTC Market Segment Mapping, 2018
5. CTC market - Porter's Analysis
6. CTC market - PESTEL analysis
7. CTC revenue share, by technology, 2018 & 2025
8. CTC enrichment segment mapping, 2018
9. CTC enrichment market , 2014 - 2025 (USD Million) 
10. CTC ex-vivo positive selection market , 2014 - 2025 (USD Million) 
11. CTC in-vivo positive selection market , 2014 - 2025 (USD Million) 
12. CTC negative selection market , 2014 - 2025 (USD Million) 
13. CTC microchips market , 2014 - 2025 (USD Million) 
14. CTC single spiral micro channel market , 2014 - 2025 (USD Million) 
15. CTC detection market , 2014 - 2025 (USD Million) 
16. CTC detection segment mapping, 2018
17. CTC immunocytochemical technologies market , 2014 - 2025 (USD Million) 
18. CTC molecular(RNA)based technologies market , 2014 - 2025 (USD Million) 
19. CTC functional in-vitro cell invasion assay market , 2014 - 2025 (USD Million) 
20. CTC xenotransplantation models market , 2014 - 2025 (USD Million) 
21. CTC analysis market , 2014 - 2025 (USD Million) 
22. CTC revenue share, by application, 2018 & 2025
23. CTC tumorogenesis research market , 2014 - 2025 (USD Million) 
24. CTC EMT biomarkers development market , 2014 - 2025 (USD Million) 
25. CTC cancer stem cell research market , 2014 - 2025 (USD Million) 
26. CTC other applications market , 2014 - 2025 (USD Million)
27. CTC revenue share, by region, 2018 & 2025
28. North America CTC market, 2014 - 2025 (USD Million)
29. U.S. CTC market, 2014 - 2025 (USD Million)
30. Canada CTC market, 2014 - 2025 (USD Million)
31. Europe CTC market, 2014 - 2025 (USD Million)
32. U.K. CTC market, 2014 - 2025 (USD Million)
33. U.K. CTC market, 2014 - 2025 (USD Million)
34. France CTC market, 2014 - 2025 (USD Million)
35. Asia Pacific CTC market, 2014 - 2025 (USD Million)
36. China CTC market, 2014 - 2025 (USD Million)
37. Japan CTC market, 2014 - 2025 (USD Million)
38. Latin America CTC market, 2014 - 2025 (USD Million)
39. Brazil CTC market, 2014 - 2025 (USD Million)
40. MEA CTC market, 2014 - 2025 (USD Million)
41. South Africa CTC market, 2014 - 2025 (USD Million)