Chronic Urticaria Or Hives - Pipeline Review, H2 2014

Published: Dec, 2014 | Pages: 67 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)

Chronic Urticaria Or Hives - Pipeline Review, H2 2014

Summary

Global Markets Direct's, 'Chronic Urticaria Or Hives - Pipeline Review, H2 2014', provides an overview of the Chronic Urticaria Or Hives's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Chronic Urticaria Or Hives, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Chronic Urticaria Or Hives and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Chronic Urticaria Or Hives
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in the therapeutics development for Chronic Urticaria Or Hives and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects 
- A review of the Chronic Urticaria Or Hives products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Chronic Urticaria Or Hives pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Chronic Urticaria Or Hives
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Chronic Urticaria Or Hives pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

 Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 5
Introduction 6
Global Markets Direct Report Coverage 6
Chronic Urticaria Or Hives Overview 7
Therapeutics Development 8
Pipeline Products for Chronic Urticaria Or Hives - Overview 8
Pipeline Products for Chronic Urticaria Or Hives - Comparative Analysis 9
Chronic Urticaria Or Hives - Therapeutics under Development by Companies 10
Chronic Urticaria Or Hives - Pipeline Products Glance 11
Late Stage Products 11
Clinical Stage Products 12
Chronic Urticaria Or Hives - Products under Development by Companies 13
Chronic Urticaria Or Hives - Companies Involved in Therapeutics Development 14
AstraZeneca PLC 14
Biofrontera AG 15
Bristol-Myers Squibb Company 16
ELORAC, Inc. 17
F. Hoffmann-La Roche Ltd. 18
FAES Farma SA 19
Genentech, Inc. 20
Merck & Co., Inc. 21
Chronic Urticaria Or Hives - Therapeutics Assessment 22
Assessment by Monotherapy Products 22
Assessment by Target 23
Assessment by Mechanism of Action 25
Assessment by Route of Administration 27
Assessment by Molecule Type 29
Drug Profiles 31
abatacept (recombinant) - Drug Profile 31
Product Description 31
Mechanism of Action 31
R&D Progress 31
AZD-1981 - Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
BF-Derm-1 - Drug Profile 35
Product Description 35
Mechanism of Action 35
R&D Progress 35
bilastine - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
cidoxepin hydrochloride - Drug Profile 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
desloratadine - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
JDP-205 - Drug Profile 40
Product Description 40
Mechanism of Action 40
R&D Progress 40
omalizumab - Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
quilizumab - Drug Profile 43
Product Description 43
Mechanism of Action 43
R&D Progress 43
Chronic Urticaria Or Hives - Recent Pipeline Updates 45
Chronic Urticaria Or Hives - Dormant Projects 52
Chronic Urticaria Or Hives - Discontinued Products 53
Chronic Urticaria Or Hives - Product Development Milestones 54
Featured News & Press Releases 54
Aug 28, 2014: Novartis announces that Xolair is approved in Canada as a licensed therapy for chronic idiopathic urticaria (CIU) patients unresponsive to antihistamines 54
May 07, 2014: FDA Approves Xolair for Treatment of Chronic Hives 55
Mar 21, 2014: Novartis announces US FDA approval of Xolair for chronic idiopathic urticaria 55
Mar 06, 2014: Novartis announces Xolair approved in EU as first and only licensed therapy for chronic spontaneous urticaria patients unresponsive to antihistamines 57
Jan 24, 2014: Novartis reports positive opinion from CHMP for Xolair in severe form of skin disease CSU, a debilitating form of hives and chronic itch 58
Oct 11, 2013: FDA Files Genentech's Supplemental Biologics License Application of Xolair for Chronic Idiopathic Urticaria 60
Sep 30, 2013: Novartis to reveal landmark Phase III results of omalizumab at upcoming EADV 2013 congress 61
Jun 26, 2013: Novartis Reports New Phase III Data Showing Omalizumab Significantly Improves Itch In Patients With Severe Form Of CSU 62
Mar 20, 2013: Omalizumab Shows Promise In Eliminating Symptoms Of Chronic Urticaria, Study Finds 64
Feb 24, 2013: Genentech Reports Omalizumab Meets Primary Endpoint In Phase III Results In Patients With Chronic Form Of Hives Who Failed Standard Therapy 64
Appendix 66
Methodology 66
Coverage 66
Secondary Research 66
Primary Research 66
Expert Panel Validation 66
Contact Us 67
Disclaimer 67

List of Tables
Number of Products under Development for Chronic Urticaria Or Hives, H2 2014 8
Number of Products under Development for Chronic Urticaria Or Hives - Comparative Analysis, H2 2014 9
Number of Products under Development by Companies, H2 2014 10
Comparative Analysis by Late Stage Development, H2 2014 11
Comparative Analysis by Clinical Stage Development, H2 2014 12
Products under Development by Companies, H2 2014 13
Chronic Urticaria Or Hives - Pipeline by AstraZeneca PLC, H2 2014 14
Chronic Urticaria Or Hives - Pipeline by Biofrontera AG, H2 2014 15
Chronic Urticaria Or Hives - Pipeline by Bristol-Myers Squibb Company, H2 2014 16
Chronic Urticaria Or Hives - Pipeline by ELORAC, Inc., H2 2014 17
Chronic Urticaria Or Hives - Pipeline by F. Hoffmann-La Roche Ltd., H2 2014 18
Chronic Urticaria Or Hives - Pipeline by FAES Farma SA, H2 2014 19
Chronic Urticaria Or Hives - Pipeline by Genentech, Inc., H2 2014 20
Chronic Urticaria Or Hives - Pipeline by Merck & Co., Inc., H2 2014 21
Assessment by Monotherapy Products, H2 2014 22
Number of Products by Stage and Target, H2 2014 24
Number of Products by Stage and Mechanism of Action, H2 2014 26
Number of Products by Stage and Route of Administration, H2 2014 28
Number of Products by Stage and Molecule Type, H2 2014 30
Chronic Urticaria Or Hives Therapeutics - Recent Pipeline Updates, H2 2014 45
Chronic Urticaria Or Hives - Dormant Projects, H2 2014 52
Chronic Urticaria Or Hives - Discontinued Products, H2 2014 53