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Published: Feb, 2015 | Pages:
74 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Chemotherapy Induced Peripheral Neuropathy - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Chemotherapy Induced Peripheral Neuropathy - Pipeline Review, H1 2015', provides an overview of the Chemotherapy Induced Peripheral Neuropathy's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Chemotherapy Induced Peripheral Neuropathy, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Chemotherapy Induced Peripheral Neuropathy and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Chemotherapy Induced Peripheral Neuropathy - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Chemotherapy Induced Peripheral Neuropathy and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Chemotherapy Induced Peripheral Neuropathy products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Chemotherapy Induced Peripheral Neuropathy pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reason to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Chemotherapy Induced Peripheral Neuropathy - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Chemotherapy Induced Peripheral Neuropathy pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Chemotherapy Induced Peripheral Neuropathy Overview 8 Therapeutics Development 9 Pipeline Products for Chemotherapy Induced Peripheral Neuropathy - Overview 9 Pipeline Products for Chemotherapy Induced Peripheral Neuropathy - Comparative Analysis 10 Chemotherapy Induced Peripheral Neuropathy - Therapeutics under Development by Companies 11 Chemotherapy Induced Peripheral Neuropathy - Therapeutics under Investigation by Universities/Institutes 13 Chemotherapy Induced Peripheral Neuropathy - Pipeline Products Glance 14 Clinical Stage Products 14 Early Stage Products 15 Chemotherapy Induced Peripheral Neuropathy - Products under Development by Companies 16 Chemotherapy Induced Peripheral Neuropathy - Products under Investigation by Universities/Institutes 17 Chemotherapy Induced Peripheral Neuropathy - Companies Involved in Therapeutics Development 18 DARA BioSciences, Inc. 18 Eisai Co., Ltd. 19 Immune Pharmaceuticals, Ltd. 20 Laboratorios Del Dr. Esteve S.A. 21 MAKScientific, LLC 22 Mertiva AB 23 Paladin Labs Inc. 24 Panacea Pharmaceuticals, Inc. 25 PharmatrophiX, Inc. 26 Spectrum Pharmaceuticals, Inc. 27 Spinifex Pharmaceuticals Pty Limited 28 Virobay Inc. 29 Chemotherapy Induced Peripheral Neuropathy - Therapeutics Assessment 30 Assessment by Monotherapy Products 30 Assessment by Combination Products 31 Assessment by Target 32 Assessment by Mechanism of Action 34 Assessment by Route of Administration 36 Assessment by Molecule Type 38 Drug Profiles 40 (amitriptyline + ketamine hydrochloride) - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 AK-295 - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 AL-309 - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 AM-1710 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 E-2072 - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 E-52862 - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 EMA-401 - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Gene Therapy for Chemotherapy Induced Peripheral Neuropathy - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 KRN-5500 - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 LM11A-31 - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 PAN-811 - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 PGN-703 - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 Small Molecule for Chemotherapy Induced Neuropathy - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 Small Molecules for Peripheral Neuropathy and Amyotrophic Lateral Sclerosis - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 SPI-205 - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 VBY-036 - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 Chemotherapy Induced Peripheral Neuropathy - Recent Pipeline Updates 61 Chemotherapy Induced Peripheral Neuropathy - Dormant Projects 67 Chemotherapy Induced Peripheral Neuropathy - Discontinued Products 68 Chemotherapy Induced Peripheral Neuropathy - Product Development Milestones 69 Featured News & Press Releases 69 Feb 25, 2014: DARA BioSciences' KRN5500 Receives Orphan Drug Designation From FDA 69 Jun 04, 2012: EpiCept Receives Scientific Advice From EMA For AmiKet CIPN Program 69 Apr 10, 2012: EpiCept's AmiKet Receives Fast Track Designation From FDA 70 Mar 28, 2012: Allon Receives US Patent Covering Use Of Its Neuroprotective Technology Platform 71 Feb 07, 2012: EpiCept Files For AmiKet Fast Track Designation 71 Dec 23, 2011: EpiCept Receives FDA Permission To Initiate AmiKet Phase III Clinical Development 72 Appendix 73 Methodology 73 Coverage 73 Secondary Research 73 Primary Research 73 Expert Panel Validation 73 Contact Us 73 Disclaimer 74
List of Tables Number of Products under Development for Chemotherapy Induced Peripheral Neuropathy, H1 2015 9 Number of Products under Development for Chemotherapy Induced Peripheral Neuropathy - Comparative Analysis, H1 2015 10 Number of Products under Development by Companies, H1 2015 12 Number of Products under Investigation by Universities/Institutes, H1 2015 13 Comparative Analysis by Clinical Stage Development, H1 2015 14 Comparative Analysis by Early Stage Development, H1 2015 15 Products under Development by Companies, H1 2015 16 Products under Investigation by Universities/Institutes, H1 2015 17 Chemotherapy Induced Peripheral Neuropathy - Pipeline by DARA BioSciences, Inc., H1 2015 18 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Eisai Co., Ltd., H1 2015 19 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Immune Pharmaceuticals, Ltd., H1 2015 20 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Laboratorios Del Dr. Esteve S.A., H1 2015 21 Chemotherapy Induced Peripheral Neuropathy - Pipeline by MAKScientific, LLC, H1 2015 22 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Mertiva AB, H1 2015 23 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Paladin Labs Inc., H1 2015 24 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Panacea Pharmaceuticals, Inc., H1 2015 25 Chemotherapy Induced Peripheral Neuropathy - Pipeline by PharmatrophiX, Inc., H1 2015 26 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Spectrum Pharmaceuticals, Inc., H1 2015 27 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Spinifex Pharmaceuticals Pty Limited, H1 2015 28 Chemotherapy Induced Peripheral Neuropathy - Pipeline by Virobay Inc., H1 2015 29 Assessment by Monotherapy Products, H1 2015 30 Assessment by Combination Products, H1 2015 31 Number of Products by Stage and Target, H1 2015 33 Number of Products by Stage and Mechanism of Action, H1 2015 35 Number of Products by Stage and Route of Administration, H1 2015 37 Number of Products by Stage and Molecule Type, H1 2015 39 Chemotherapy Induced Peripheral Neuropathy Therapeutics - Recent Pipeline Updates, H1 2015 61 Chemotherapy Induced Peripheral Neuropathy - Dormant Projects, H1 2015 67 Chemotherapy Induced Peripheral Neuropathy - Discontinued Products, H1 2015 68
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