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Published: Nov, 2014 | Pages:
89 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
Chemotherapy Induced Nausea and Vomiting - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'Chemotherapy Induced Nausea and Vomiting - Pipeline Review, H2 2014', provides an overview of the Chemotherapy Induced Nausea and Vomiting's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Chemotherapy Induced Nausea and Vomiting, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Chemotherapy Induced Nausea and Vomiting and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Chemotherapy Induced Nausea and Vomiting - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Chemotherapy Induced Nausea and Vomiting and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Chemotherapy Induced Nausea and Vomiting products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Chemotherapy Induced Nausea and Vomiting pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Chemotherapy Induced Nausea and Vomiting - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Chemotherapy Induced Nausea and Vomiting pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Chemotherapy Induced Nausea and Vomiting Overview 8 Therapeutics Development 9 Pipeline Products for Chemotherapy Induced Nausea and Vomiting - Overview 9 Pipeline Products for Chemotherapy Induced Nausea and Vomiting - Comparative Analysis 10 Chemotherapy Induced Nausea and Vomiting - Therapeutics under Development by Companies 11 Chemotherapy Induced Nausea and Vomiting - Pipeline Products Glance 13 Late Stage Products 13 Clinical Stage Products 14 Early Stage Products 15 Unknown Stage Products 16 Chemotherapy Induced Nausea and Vomiting - Products under Development by Companies 17 Chemotherapy Induced Nausea and Vomiting - Companies Involved in Therapeutics Development 18 Acacia Pharma Ltd. 18 Aphios Corporation 19 BioDelivery Sciences International, Inc. 20 Genovate Biotechnology Co., LTD. 21 Helsinn Holding S.A. 22 Heron Therapeutics, Inc. 23 INSYS Therapeutics, Inc. 24 Kyowa Hakko Kirin Co., Ltd. 25 Merck & Co., Inc. 26 RedHill Biopharma Ltd. 27 Shin Nippon Biomedical Laboratories, Ltd. 28 Suda Ltd 29 Teikoku Pharma USA, Inc. 30 Tesaro, Inc. 31 Chemotherapy Induced Nausea and Vomiting - Therapeutics Assessment 32 Assessment by Monotherapy Products 32 Assessment by Combination Products 33 Assessment by Target 34 Assessment by Mechanism of Action 36 Assessment by Route of Administration 38 Assessment by Molecule Type 40 Drug Profiles 41 (netupitant + palonosetron hydrochloride) - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 APD-403 - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 APD-421 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 aprepitant - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 aprepitant - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 dronabinol - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 dronabinol - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 granisetron - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 granisetron - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 granisetron - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 granisetron ER - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 granisetron ER - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 ondansetron hydrochloride - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 ondansetron hydrochloride - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 ondansetron hydrochloride CR - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 rolapitant hydrochloride - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 TPW-146 - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 Chemotherapy Induced Nausea and Vomiting - Recent Pipeline Updates 64 Chemotherapy Induced Nausea and Vomiting - Dormant Projects 77 Chemotherapy Induced Nausea and Vomiting - Discontinued Products 78 Chemotherapy Induced Nausea and Vomiting - Product Development Milestones 79 Featured News & Press Releases 79 Nov 06, 2014: Heron Therapeutics Discloses HTX-019 Intravenous Formulation of NK-1 Receptor Antagonist for Prevention of CINV 79 Nov 06, 2014: Heron Therapeutics Discloses New Proprietary Intravenous Formulation of NK-1 Receptor Antagonist for Prevention of CINV 79 Oct 10, 2014: FDA approves Akynzeo for nausea and vomiting associated with cancer chemotherapy 80 Sep 27, 2014: Rolapitant Reduces Nausea and Vomiting in Phase III Trial 81 Sep 08, 2014: OPKO Licensee TESARO Submits New Drug Application for Rolapitant 81 Jul 10, 2014: Helsinn Announces That Phase 2/3 Pivotal Trials for NEPA (netupitant 300mg + oral palonosetron 0.50mg), Will be Published in the Annals of Oncology 82 Jul 08, 2014: Insys Therapeutics Updates Timing of NDA for Dronabinol Oral Solution 83 Jun 30, 2014: Merck Announces Data from Investigational Phase 3 Study on EMEND (aprepitant) for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Children Undergoing Emetogenic Chemotherapy 84 Jun 02, 2014: Heron Therapeutics Provides Update on SUSTOL Program 85 Jun 01, 2014: Tesaro Summarizes Phase 3 Rolapitant Data Presented at the 2014 American Society of Clinical Oncology Annual Meeting and Provides an Update on Niraparib Development Strategy 86 Appendix 88 Methodology 88 Coverage 88 Secondary Research 88 Primary Research 88 Expert Panel Validation 88 Contact Us 89 Disclaimer 89
List of Tables Number of Products under Development for Chemotherapy Induced Nausea and Vomiting, H2 2014 9 Number of Products under Development for Chemotherapy Induced Nausea and Vomiting - Comparative Analysis, H2 2014 10 Number of Products under Development by Companies, H2 2014 12 Comparative Analysis by Late Stage Development, H2 2014 13 Comparative Analysis by Clinical Stage Development, H2 2014 14 Comparative Analysis by Early Stage Development, H2 2014 15 Comparative Analysis by Unknown Stage Development, H2 2014 16 Products under Development by Companies, H2 2014 17 Chemotherapy Induced Nausea and Vomiting - Pipeline by Acacia Pharma Ltd., H2 2014 18 Chemotherapy Induced Nausea and Vomiting - Pipeline by Aphios Corporation, H2 2014 19 Chemotherapy Induced Nausea and Vomiting - Pipeline by BioDelivery Sciences International, Inc., H2 2014 20 Chemotherapy Induced Nausea and Vomiting - Pipeline by Genovate Biotechnology Co., LTD., H2 2014 21 Chemotherapy Induced Nausea and Vomiting - Pipeline by Helsinn Holding S.A., H2 2014 22 Chemotherapy Induced Nausea and Vomiting - Pipeline by Heron Therapeutics, Inc., H2 2014 23 Chemotherapy Induced Nausea and Vomiting - Pipeline by INSYS Therapeutics, Inc., H2 2014 24 Chemotherapy Induced Nausea and Vomiting - Pipeline by Kyowa Hakko Kirin Co., Ltd., H2 2014 25 Chemotherapy Induced Nausea and Vomiting - Pipeline by Merck & Co., Inc., H2 2014 26 Chemotherapy Induced Nausea and Vomiting - Pipeline by RedHill Biopharma Ltd., H2 2014 27 Chemotherapy Induced Nausea and Vomiting - Pipeline by Shin Nippon Biomedical Laboratories, Ltd., H2 2014 28 Chemotherapy Induced Nausea and Vomiting - Pipeline by Suda Ltd, H2 2014 29 Chemotherapy Induced Nausea and Vomiting - Pipeline by Teikoku Pharma USA, Inc., H2 2014 30 Chemotherapy Induced Nausea and Vomiting - Pipeline by Tesaro, Inc., H2 2014 31 Assessment by Monotherapy Products, H2 2014 32 Assessment by Combination Products, H2 2014 33 Number of Products by Stage and Target, H2 2014 35 Number of Products by Stage and Mechanism of Action, H2 2014 37 Number of Products by Stage and Route of Administration, H2 2014 39 Number of Products by Stage and Molecule Type, H2 2014 40 Chemotherapy Induced Nausea and Vomiting Therapeutics - Recent Pipeline Updates, H2 2014 64 Chemotherapy Induced Nausea and Vomiting - Dormant Projects, H2 2014 77 Chemotherapy Induced Nausea and Vomiting - Discontinued Products, H2 2014 78
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