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Published: Jan, 2015 | Pages:
91 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Chemotherapy Induced Nausea and Vomiting - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Chemotherapy Induced Nausea and Vomiting - Pipeline Review, H1 2015', provides an overview of the Chemotherapy Induced Nausea and Vomiting's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Chemotherapy Induced Nausea and Vomiting, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Chemotherapy Induced Nausea and Vomiting and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Chemotherapy Induced Nausea and Vomiting - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Chemotherapy Induced Nausea and Vomiting and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Chemotherapy Induced Nausea and Vomiting products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Chemotherapy Induced Nausea and Vomiting pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons To Buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Chemotherapy Induced Nausea and Vomiting - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Chemotherapy Induced Nausea and Vomiting pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Chemotherapy Induced Nausea and Vomiting Overview 8 Therapeutics Development 9 Pipeline Products for Chemotherapy Induced Nausea and Vomiting - Overview 9 Pipeline Products for Chemotherapy Induced Nausea and Vomiting - Comparative Analysis 10 Chemotherapy Induced Nausea and Vomiting - Therapeutics under Development by Companies 11 Chemotherapy Induced Nausea and Vomiting - Pipeline Products Glance 13 Late Stage Products 13 Clinical Stage Products 14 Early Stage Products 15 Unknown Stage Products 16 Chemotherapy Induced Nausea and Vomiting - Products under Development by Companies 17 Chemotherapy Induced Nausea and Vomiting - Companies Involved in Therapeutics Development 19 Acacia Pharma Ltd. 19 Aphios Corporation 20 Genovate Biotechnology Co., LTD. 21 Helsinn Holding S.A. 22 Heron Therapeutics, Inc. 23 INSYS Therapeutics, Inc. 24 Kyowa Hakko Kirin Co., Ltd. 25 Merck & Co., Inc. 26 RedHill Biopharma Ltd. 27 Shin Nippon Biomedical Laboratories, Ltd. 28 Sparsha Pharma International Pvt. Ltd. 29 Suda Ltd 30 Teikoku Pharma USA, Inc. 31 Tesaro, Inc. 32 Chemotherapy Induced Nausea and Vomiting - Therapeutics Assessment 33 Assessment by Monotherapy Products 33 Assessment by Combination Products 34 Assessment by Target 35 Assessment by Mechanism of Action 37 Assessment by Route of Administration 39 Assessment by Molecule Type 41 Drug Profiles 42 (netupitant + palonosetron hydrochloride) - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 APD-403 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 APD-421 - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 aprepitant - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 aprepitant - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 dronabinol - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 dronabinol - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 Drug to Antagonize 5-HT3 for Chemotherapy Induced Nausea and Vomiting - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 granisetron - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 granisetron - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 granisetron ER - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 granisetron ER - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 ondansetron hydrochloride - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 ondansetron hydrochloride - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 ondansetron hydrochloride CR - Drug Profile 63 Product Description 63 Mechanism of Action 63 R&D Progress 63 rolapitant hydrochloride - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 TPW-146 - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 Chemotherapy Induced Nausea and Vomiting - Recent Pipeline Updates 66 Chemotherapy Induced Nausea and Vomiting - Dormant Projects 80 Chemotherapy Induced Nausea and Vomiting - Discontinued Products 81 Chemotherapy Induced Nausea and Vomiting - Product Development Milestones 82 Featured News & Press Releases 82 Jan 12, 2015: Insys Therapeutics Plans to Submit NDA for Dronabinol Oral Solution in First Quarter of 2015 82 Jan 12, 2015: Insys Therapeutics To Initiate Phase III Pivotal PK Study For Ondansetron 82 Dec 31, 2014: RedHill Biopharma Announces Acceptance for Review of BEKINDA European Marketing Application for Oncology Support 82 Dec 09, 2014: RedHill Biopharma Submits BEKINDA (RHB-102) European Marketing Authorization Application for Oncology Support 83 Nov 06, 2014: Heron Therapeutics Discloses HTX-019 Intravenous Formulation of NK-1 Receptor Antagonist for Prevention of CINV 85 Nov 06, 2014: Heron Therapeutics Discloses New Proprietary Intravenous Formulation of NK-1 Receptor Antagonist for Prevention of CINV 85 Oct 10, 2014: FDA approves Akynzeo for nausea and vomiting associated with cancer chemotherapy 86 Sep 27, 2014: Rolapitant Reduces Nausea and Vomiting in Phase III Trial 86 Sep 08, 2014: OPKO Licensee TESARO Submits New Drug Application for Rolapitant 87 Jul 10, 2014: Helsinn Announces That Phase 2/3 Pivotal Trials for NEPA (netupitant 300mg + oral palonosetron 0.50mg), Will be Published in the Annals of Oncology 88 Appendix 90 Methodology 90 Coverage 90 Secondary Research 90 Primary Research 90 Expert Panel Validation 90 Contact Us 91 Disclaimer 91
List of Tables Number of Products under Development for Chemotherapy Induced Nausea and Vomiting, H1 2015 9 Number of Products under Development for Chemotherapy Induced Nausea and Vomiting - Comparative Analysis, H1 2015 10 Number of Products under Development by Companies, H1 2015 12 Comparative Analysis by Late Stage Development, H1 2015 13 Comparative Analysis by Clinical Stage Development, H1 2015 14 Comparative Analysis by Early Stage Development, H1 2015 15 Comparative Analysis by Unknown Stage Development, H1 2015 16 Products under Development by Companies, H1 2015 17 Products under Development by Companies, H1 2015 (Contd..1) 18 Chemotherapy Induced Nausea and Vomiting - Pipeline by Acacia Pharma Ltd., H1 2015 19 Chemotherapy Induced Nausea and Vomiting - Pipeline by Aphios Corporation, H1 2015 20 Chemotherapy Induced Nausea and Vomiting - Pipeline by Genovate Biotechnology Co., LTD., H1 2015 21 Chemotherapy Induced Nausea and Vomiting - Pipeline by Helsinn Holding S.A., H1 2015 22 Chemotherapy Induced Nausea and Vomiting - Pipeline by Heron Therapeutics, Inc., H1 2015 23 Chemotherapy Induced Nausea and Vomiting - Pipeline by INSYS Therapeutics, Inc., H1 2015 24 Chemotherapy Induced Nausea and Vomiting - Pipeline by Kyowa Hakko Kirin Co., Ltd., H1 2015 25 Chemotherapy Induced Nausea and Vomiting - Pipeline by Merck & Co., Inc., H1 2015 26 Chemotherapy Induced Nausea and Vomiting - Pipeline by RedHill Biopharma Ltd., H1 2015 27 Chemotherapy Induced Nausea and Vomiting - Pipeline by Shin Nippon Biomedical Laboratories, Ltd., H1 2015 28 Chemotherapy Induced Nausea and Vomiting - Pipeline by Sparsha Pharma International Pvt. Ltd., H1 2015 29 Chemotherapy Induced Nausea and Vomiting - Pipeline by Suda Ltd, H1 2015 30 Chemotherapy Induced Nausea and Vomiting - Pipeline by Teikoku Pharma USA, Inc., H1 2015 31 Chemotherapy Induced Nausea and Vomiting - Pipeline by Tesaro, Inc., H1 2015 32 Assessment by Monotherapy Products, H1 2015 33 Assessment by Combination Products, H1 2015 34 Number of Products by Stage and Target, H1 2015 36 Number of Products by Stage and Mechanism of Action, H1 2015 38 Number of Products by Stage and Route of Administration, H1 2015 40 Number of Products by Stage and Molecule Type, H1 2015 41 Chemotherapy Induced Nausea and Vomiting Therapeutics - Recent Pipeline Updates, H1 2015 66 Chemotherapy Induced Nausea and Vomiting - Dormant Projects, H1 2015 80 Chemotherapy Induced Nausea and Vomiting - Discontinued Products, H1 2015 81
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