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Published: Jan, 2015 | Pages:
67 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Cachexia - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Cachexia - Pipeline Review, H1 2015', provides an overview of the Cachexia's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Cachexia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Cachexia and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Cachexia - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Cachexia and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Cachexia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Cachexia pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Cachexia - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Cachexia pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 Cachexia Overview 8 Therapeutics Development 9 Pipeline Products for Cachexia - Overview 9 Pipeline Products for Cachexia - Comparative Analysis 10 Cachexia - Therapeutics under Development by Companies 11 Cachexia - Therapeutics under Investigation by Universities/Institutes 12 Cachexia - Pipeline Products Glance 13 Clinical Stage Products 13 Early Stage Products 14 Cachexia - Products under Development by Companies 15 Cachexia - Products under Investigation by Universities/Institutes 16 Cachexia - Companies Involved in Therapeutics Development 17 Aphios Corporation 17 AVEO Pharmaceuticals, Inc. 18 BioLineRx, Ltd. 19 Calzada Limited 20 Cytokinetics, Inc. 21 GlaxoSmithKline plc 22 MI.TO. Technology S.r.L. 23 Myos Corporation 24 Novartis AG 25 Palatin Technologies, Inc. 26 Pfizer Inc. 27 Rhythm Pharmaceuticals 28 Cachexia - Therapeutics Assessment 29 Assessment by Monotherapy Products 29 Assessment by Target 30 Assessment by Mechanism of Action 32 Assessment by Route of Administration 34 Assessment by Molecule Type 36 Drug Profiles 38 AOD-9604 - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 AV-380 - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 bimagrumab - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 BL-5040 - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 CK-2066260 - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 DLN-101 - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 dronabinol - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 Drugs to Inhibit Activin Receptor for Cachexia - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 PF-06260414 - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 Protein for Musculoskeletal Disorders - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 relamorelin - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51 Small Molecules to Inhibit Furin for Sarcopenia and Cachexia - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 Small Molecules to Inhibit JAK3 for Sarcopenia and Cachexia - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 Small Molecules to Inversely Agonize Beta3-Adrenoreceptor for Cachexia, Metabolic Syndrome and Heart Failure - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 Small Molecules to Modulate Melanocortin-4 Receptor for Cachexia - Drug Profile 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 Synthetic Peptide to Antagonize MC3 and MC4 Receptor for Cachexia - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 Cachexia - Recent Pipeline Updates 58 Cachexia - Dormant Projects 63 Cachexia - Discontinued Products 64 Cachexia - Product Development Milestones 65 Featured News & Press Releases 65 Mar 13, 2012: Calzada Announces Positive Results Of AOD9604 In Cartilage And Muscle Repair Models 65 Jun 04, 2002: Aphios Receives National Cancer Institute Grant For Developing Natural Cannabinoid Products for Medical Use 65 Appendix 66 Methodology 66 Coverage 66 Secondary Research 66 Primary Research 66 Expert Panel Validation 66 Contact Us 66 Disclaimer 67
List of Tables Number of Products under Development for Cachexia, H1 2015 9 Number of Products under Development for Cachexia - Comparative Analysis, H1 2015 10 Number of Products under Development by Companies, H1 2015 11 Number of Products under Investigation by Universities/Institutes, H1 2015 12 Comparative Analysis by Clinical Stage Development, H1 2015 13 Comparative Analysis by Early Stage Development, H1 2015 14 Products under Development by Companies, H1 2015 15 Products under Investigation by Universities/Institutes, H1 2015 16 Cachexia - Pipeline by Aphios Corporation, H1 2015 17 Cachexia - Pipeline by AVEO Pharmaceuticals, Inc., H1 2015 18 Cachexia - Pipeline by BioLineRx, Ltd., H1 2015 19 Cachexia - Pipeline by Calzada Limited, H1 2015 20 Cachexia - Pipeline by Cytokinetics, Inc., H1 2015 21 Cachexia - Pipeline by GlaxoSmithKline plc, H1 2015 22 Cachexia - Pipeline by MI.TO. Technology S.r.L., H1 2015 23 Cachexia - Pipeline by Myos Corporation, H1 2015 24 Cachexia - Pipeline by Novartis AG, H1 2015 25 Cachexia - Pipeline by Palatin Technologies, Inc., H1 2015 26 Cachexia - Pipeline by Pfizer Inc., H1 2015 27 Cachexia - Pipeline by Rhythm Pharmaceuticals, H1 2015 28 Assessment by Monotherapy Products, H1 2015 29 Number of Products by Stage and Target, H1 2015 31 Number of Products by Stage and Mechanism of Action, H1 2015 33 Number of Products by Stage and Route of Administration, H1 2015 35 Number of Products by Stage and Molecule Type, H1 2015 37 Cachexia Therapeutics - Recent Pipeline Updates, H1 2015 58 Cachexia - Dormant Projects, H1 2015 63 Cachexia - Discontinued Products, H1 2015 64
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