Bone Graft And Substitutes Market Size, Share & Trends Analysis Report By Product (Allograft, Synthetic), By Application (Dental, Spinal Fusion), By Region (APAC, North America), And Segment Forecasts, 2020 - 2027

Published: Nov, 2020 | Pages: 145 | Publisher: Grand View Research
Industry: Medical Devices | Report Format: Electronic (PDF)

"Bone Graft And Substitutes Market Growth & Trends

The global bone graft and substitutes market size is expected to reach USD 3.9 billion by 2027 registering a CAGR of 5.1%, according to a new report by Grand View Research, Inc. The synthetic product segment is anticipated to have the fastest growth over the forecast period due to the products’ better biocompatibility, lesser risk of disease transmission, and better acceptance among patients as compared to allografts. However, due to the postponement of elective surgeries during the Covid-19 pandemic, the demand for orthopedic devices, including bone graft & substitutes witnessed a drastic decrease.

Increasing incidences of spinal deformities are the key growth-driving factor of the market. According to the CDC 2017 report, in the U.S., about 32% of the adult population and 60% of the aged population is affected by spinal deformities. Moreover, the advent of biocompatible synthetic grafts is expected to drive the market growth. In addition, technological advancements and the growing geriatric population are boosting product demand.

According to the Population Reference Bureau’s 2018 statistics, from 13 countries to around 82 countries across the globe are expected to have more than 20% of the geriatric population by 2050. Thus, perpetual growth in the geriatric population is anticipated to result in an increased prevalence of arthritis and joint disorders, which, in turn, will boost product demand. Key players in the market are investing in new product development and product approvals.

For instance, in March 2019, AlloSource announced ProChondrix CR would have 2 years of shelf life based on the results of real-time testing. ProChondrix CR helps in cartilage healing and is intended to match biochemical & biomechanical properties of normal hyaline cartilage, improve patient symptoms, and restore a smooth articular cartilage surface.

Bone Graft And Substitutes Market Report Highlights

• The allograft product segment accounted for the largest revenues share in 2019 and is projected to expand further at a steady CAGR of over 4% from 2020 to 2027

• The adoption of allografts is increasing due to the product properties, such as immediate structural support and osteoconductivity

• Led by the U.S., North America was the dominant regional market in 2019 and is estimated to retain its leading position over the forecast years

• This growth is mainly due to the growing awareness regarding the commercially available advanced products, higher healthcare expenditure, and well-developed healthcare structure in the region

• The Asia Pacific is anticipated to be the fastest-growing regional market from 2020 to 2027 owing to the rising medical tourism and favorable government initiatives

• The industry participants are focusing on product launches, partnerships, and acquisitions to sustain the competition

• However, the synthetic product segment, which includes ceramics, composites, polymers, and BMPs, is expected to exhibit the fastest CAGR over the forecast period

• Spinal fusion was the largest application segment in 2019 and accounted for over 60% of the overall revenue share"

 "Table of Contents

Chapter 1 Research Methodology & Scope
                 1.1 Market Segmentation & Scope
                      1.1.1 Estimates and Forecast Timeline
                 1.2 Research Methodology
                 1.3 Information Procurement
                      1.3.1 Purchased database
                      1.3.2 GVR’s Internal Database
                      1.3.3 Secondary sources
                      1.3.4 Primary Research
                      1.3.5 Details of Primary Research
                          1.3.5.1 Data for primary interviews in North America
                          1.3.5.2 Data for primary interviews in Europe
                          1.3.5.3 Data for primary interviews in Asia Pacific
                          1.3.5.4 Data for primary interviews in Latin America
                          1.3.5.5 Data for primary interviews in Middle East and Africa
                 1.4 Information or Data Analysis
                      1.4.1 Data Analysis Models
                 1.5 Market Formulation & Validation
                 1.6 Model Details
                      1.6.1 Commodity Flow Analysis (Model 1)
                          1.6.1.1 Approach 1: Commodity Flow Approach
                 1.7 List of Secondary Sources
                 1.8 List of Primary Sources
                 1.9 Abbreviations
                 1.10 Report Objectives
Chapter 2 Executive Summary
                 2.1 Market Outlook
                      2.1.1 Bone Grafts & Substitutes market Outlook, 2016-2027 (USD Million)
                 2.2 Bone Grafts & Substitutes Market Summary, 2019
Chapter 3 Bone Grafts & Substitutes Market Variables, Trends & Scope
                 3.1 Regulatory Framework
                 3.2 USFDA Consideration
                      3.2.1 Bone grafts & substitutes that found to be medically necessary
                 3.3 Reimbursement framework
                      3.3.1 CPT Coding
                      3.3.2 HCPCS Coding
                      3.3.3 Market driver analysis
                          3.3.3.1 Rising incidence of bone & joint disorders
                          3.3.3.2 Advent of biocompatible synthetic graft
                          3.3.3.3 Rising demand for dental bone grafts
                          3.3.3.4 Technological advancement
                          3.3.3.5 Rising geriatric population
                      3.3.4 Market restraint analysis
                          3.3.4.1 Stringent regulatory guidelines
                          3.3.4.2 Risk of disease transmission
                          3.3.4.3 High cost of bone grafts and substitutes
                 3.4 Bone Grafts & Substitutes Market Analysis Tools: Porters
                 3.5 PESTEL Analysis
Chapter 4 Bone Grafts & Substitutes Market: Competitive Analysis
                 4.1 Innovators
                 4.2 Key Company Market Share Analysis, 2019 (Estimated)
                 4.3 Market Leaders
                 4.4 Market Leaders by Product Segment
                 4.5 Major Deals & Strategic Alliances Analysis
                      4.5.1 product launch
                      4.5.2 Acquisitions
                      4.5.3 Product Approval
                      4.5.4 Partnership & Collaborations
                 4.6 List of private companies
Chapter 5 Bone Grafts & Substitutes Market: Product Estimates & Trend Analysis
                 5.1 Product Market Share Analysis, 2019 & 2027
                 5.2 Product Dashboard
                      5.2.1 Allograft
                          5.2.1.1 Allograft market estimates and forecasts, 2016 - 2027 (USD Million)
                          5.2.1.2 Demineralized Bone Matrix (DBM)
                               5.2.1.2.1 Demineralized Bone Matrix (DBM) market estimates and forecasts, 2016 - 2027 (USD Million)
                          5.2.1.3 Others
                               5.2.1.3.1 Others market estimates and forecasts, 2016 - 2027 (USD Million)
                      5.2.2 Synthetic
                          5.2.2.1 Synthetic market estimates and forecasts, 2016 - 2027 (USD Million)
                          5.2.2.2 Ceramic
                               5.2.2.2.1 Ceramic market estimates and forecasts, 2016 - 2027 (USD Million)
                               5.2.2.2.2 HAP
                                    5.2.2.2.2.1 HAP market estimates and forecasts, 2016 - 2027 (USD Million)
                               5.2.2.2.3 ß-TCP
                                    5.2.2.2.3.1 ß-TCP market estimates and forecasts, 2016 - 2027 (USD Million)
                               5.2.2.2.4 αlpha-tricalcium phosphate (αlpha-TCP)
                                    5.2.2.2.4.1 αlpha-TCP market estimates and forecasts, 2016 - 2027 (USD Million)
                               5.2.2.2.5 Bi-phasic calcium phosphates (BCP)
                                    5.2.2.2.5.1 Bi-phasic calcium phosphates (BCP) market estimates and forecasts, 2016 - 2027 (USD Million)
                               5.2.2.2.6 Others
                                    5.2.2.2.6.1 Others market estimates and forecasts, 2016 - 2027 (USD Million)
                          5.2.2.3 Composite
                               5.2.2.3.1 Composite market estimates and forecasts, 2016 - 2027 (USD Million)
                          5.2.2.4 Polymers
                               5.2.2.4.1 Polymers market estimates and forecasts, 2016 - 2027 (USD Million)
                          5.2.2.5 BMP
                               5.2.2.5.1 BMP market estimates and forecasts, 2016 - 2027 (USD Million)
Chapter 6 Bone Grafts & Substitutes Market: Application Estimates & Trend Analysis
                 6.1 Application Market Share Analysis, 2019 & 2027
                 6.2 Application Dashboard
                 6.3 Craniomaxillofacial
                      6.3.1 Craniomaxillofacial market estimates and forecasts, 2016 - 2027 (USD Million)
                 6.4 Dental
                      6.4.1 Dental market estimates and forecasts, 2016 - 2027 (USD Million)
                 6.5 Foot & Ankle
                      6.5.1 Foot & Ankle market estimates and forecasts, 2016 - 2027 (USD Million)
                 6.6 Joint Reconstruction
                      6.6.1 Joint Reconstruction market estimates and forecasts, 2016 - 2027 (USD Million)
                 6.7 Long Bone
                      6.7.1 Long Bone market estimates and forecasts, 2016 - 2027 (USD Million)
                 6.8 Spinal Fusion
                      6.8.1 Spinal Fusion market estimates and forecasts, 2016 - 2027 (USD Million)
Chapter 7 Bone Grafts & Substitutes Market: Regional Estimates & Trend Analysis, By, Product, & Application
                 7.1 Regional Market Snapshot
                 7.2 North America
                      7.2.1 North America Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                      7.2.2 U.S.
                          7.2.2.1 U.S. Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027(USD Million)
                      7.2.3 Canada
                          7.2.3.1 Canada Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027(USD Million)
                 7.3 Europe
                      7.3.1 Europe Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                      7.3.2 U.K.
                          7.3.2.1 U.K. Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027(USD Million)
                      7.3.3 Germany
                          7.3.3.1 Germany Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                      7.3.4 France
                          7.3.4.1 France Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                      7.3.5 Italy
                          7.3.5.1 Italy Bone Graft and Substitutes market, 2016 - 2027 (USD Million)
                      7.3.6 Spain
                          7.3.6.1 Spain Bone Graft and Substitutes market, 2016 - 2027 (USD Million)
                 7.4 Asia Pacific
                      7.4.1 Asia Pacific Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                      7.4.2 China
                          7.4.2.1 China Bone Graft and Substitutes market, 2016 - 2027 (USD Million)
                      7.4.3 Japan
                          7.4.3.1 Japan Bone Graft and Substitutes market, 2016 - 2027 (USD Million)
                      7.4.4 India
                          7.4.4.1 India Bone Graft and Substitutes market, 2016 - 2027 (USD Million)
                      7.4.5 South Korea
                          7.4.5.1 South Korea Bone Graft and Substitutes market, 2016 - 2027 (USD Million)
                 7.5 Latin America
                      7.5.1 Latin America Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                      7.5.2 Mexico
                          7.5.2.1 Mexico Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                      7.5.3 Brazil
                          7.5.3.1 Brazil Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                 7.6 MEA
                      7.6.1 MEA Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
                      7.6.2 South Africa
                          7.6.2.1 South Africa Bone Grafts & Substitutes market estimates and forecasts, 2016 - 2027 (USD Million)
Chapter 8 Company Profiles
                 8.1 AlloSource
                      8.1.1 Company Overview
                      8.1.2 Financial Performance
                      8.1.3 Product Benchmarking
                      8.1.4 Strategic Initiatives
                 8.2 Baxter
                      8.2.1 Company Overview
                      8.2.2 Financial Performance
                      8.2.3 Product Benchmarking
                      8.2.4 Strategic Initiatives
                 8.3 DePuy Synthes, Inc.
                      8.3.1 Company Overview
                      8.3.2 Financial Performance
                      8.3.3 Product Benchmarking
                      8.3.4 Strategic Initiatives
                 8.4 Medtronic PLC
                      8.4.1 Company Overview
                      8.4.2 Financial Performance
                      8.4.3 Product Benchmarking
                      8.4.4 Strategic Initiatives
                 8.5 Nuvasive, Inc.
                      8.5.1 Company Overview
                      8.5.2 Financial Performance
                      8.5.3 Product Benchmarking
                      8.5.4 Strategic Initiatives
                 8.6 Orthofix Holdings, Inc.
                      8.6.1 Company Overview
                      8.6.2 Financial Performance
                      8.6.3 Product Benchmarking
                      8.6.4 Strategic Initiatives
                 8.7 Smith & Nephew, Inc.
                      8.7.1 Company Overview
                      8.7.2 Financial Performance
                      8.7.3 Product Benchmarking
                      8.7.4 Strategic Initiatives
                 8.8 Stryker Corporation
                      8.8.1 Company Overview
                      8.8.2 Financial Performance
                      8.8.3 Product Benchmarking
                      8.8.4 Strategic Initiatives
                 8.9 Wright Medical Group N.V.
                      8.9.1 Company Overview
                      8.9.2 Financial Performance
                      8.9.3 Product Benchmarking
                      8.9.4 Strategic Initiatives
                 8.10 OST Développement
                      8.10.1 Company Overview
                      8.10.2 Financial Performance
                      8.10.3 Product Benchmarking
                 8.11 Zimmer Biomet
                      8.11.1 Company Overview
                      8.11.2 Financial Performance
                      8.11.3 Product Benchmarking
                      8.11.4 Strategic Initiatives
                 8.12 Geistlich Pharma AG
                      8.12.1 Company Overview
                      8.12.2 Financial Performance
                      8.12.3 Product Benchmarking
                      8.12.4 Strategic Initiatives
                 8.13 TBF Tissue Engineering
                      8.13.1 Company Overview
                      8.13.2 Product Benchmarking
                 8.14 Biobank
                      8.14.1 Company Overview
                      8.14.2 Financial Performance
                      8.14.3 Product Benchmarking
"

"List of Tables

TABLE 1 List of secondary sources
TABLE 2 Primary interview details: North America
TABLE 3 Primary interview details: Europe
TABLE 4 Primary interview details: APAC
TABLE 5 Primary interview details: Latin America
TABLE 6 Primary interview details: MEA
TABLE 7 List of abbreviation
TABLE 8 Average cost of bone graft (2019)
TABLE 9 North America Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 10 North America Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 11 U.S. Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 12 U.S. Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 13 Canada Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 14 Canada Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 15 Europe Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 16 Europe Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 17 U.K. Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 18 U.K. Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 19 Germany Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 20 Germany Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 21 France Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 22 France Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 23 Italy Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 24 Italy Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 25 Spain Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 26 Spain Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 27 Asia Pacific Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 28 Asia Pacific Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 29 Japan Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 30 Japan Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 31 China Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 32 China Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 33 India Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 34 India Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 35 South Korea Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 36 South Korea Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 37 Latin America Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 38 Latin America Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 39 Brazil Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 40 Brazil Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 41 Mexico Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 42 Mexico Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 43 MEA Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 44 MEA Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 45 South Africa Bone Graft & Substitutes market estimates and forecasts, by product, 2016 - 2027 (USD million)
TABLE 46 South Africa Bone Graft & Substitutes market estimates and forecasts, by application, 2016 - 2027 (USD million)
TABLE 47 Major merger & acquisitions
TABLE 48 List of key emerging companies
TABLE 49 List of key private companies
TABLE 50 List of Distributors"	"List of Figures

FIG. 1 Market segmentation
FIG. 2 Market research process
FIG. 3 Data triangulation techniques
FIG. 4 Primary research pattern
FIG. 5 Primary interviews in North America
FIG. 6 Primary interviews in Europe
FIG. 7 Primary interviews in Asia Pacific
FIG. 8 Primary interviews in Latin America
FIG. 9 Primary interviews in Middle East and Africa
FIG. 10 Market research approaches
FIG. 11 Value-chain-based sizing & forecasting
FIG. 12 QFD modeling for market share assessment
FIG. 13 Market formulation & validation
FIG. 14 Commodity flow analysis
FIG. 15 BGS market, 2016-2027 (USD Millions)
FIG. 16 Bone Grafts & Substitutes market snapshot
FIG. 17 Bone Grafts & Substitutes market driver impact
FIG. 18 Common Causes Of Spinal Injury, 2018
FIG. 19 Age Distribution of Spinal Fusion Surgeries, 2018
FIG. 20 Bone Grafts & Substitutes market restraint impact
FIG. 21 Bone grafts & substitutes market Porter’s five forces analysis
FIG. 22 Bone grafts & substitutes market PESTEL analysis
FIG. 23 Company market share analysis (Estimated)
FIG. 24 Market leader by product segment
FIG. 25 Strategy mapping
FIG. 26 Bone grafts & substitutes market: Product movement analysis
FIG. 27 Bone grafts & substitutes market product dashboard
FIG. 28 Global allograft market, 2016 - 2027 (USD Million)
FIG. 29 Global demineralized bone matrix (DBM) market, 2016 - 2027 (USD Million)
FIG. 30 Global others market, 2016 - 2027 (USD Million)
FIG. 31 Global synthetic market, 2016 - 2027 (USD Million)
FIG. 32 Global Ceramic market, 2016 - 2027 (USD Million)
FIG. 33 Global HAP market, 2016 - 2027 (USD Million)
FIG. 34 Global ß-TCP market, 2016 - 2027 (USD Million)
FIG. 35 Global α-TCP market, 2016 - 2027 (USD Million)
FIG. 36 Global bi-phasic calcium phosphates (BCP) market, 2016 - 2027 (USD Million)
FIG. 37 Global others market, 2016 - 2027 (USD Million)
FIG. 38 Global composite market, 2016 - 2027 (USD Million)
FIG. 39 Global polymers market, 2016 - 2027 (USD Million)
FIG. 40 Global BMP market, 2016 - 2027 (USD Million)
FIG. 41 Bone Grafts & Substitutes market: Application movement analysis
FIG. 42 Bone Grafts & Substitutes Application dashboard
FIG. 43 Global craniomaxillofacial market, 2016 - 2027 (USD Million)
FIG. 44 Global dental market, 2016 - 2027 (USD Million)
FIG. 45 Global foot & ankle market, 2016 - 2027 (USD Million)
FIG. 46 Global joint reconstruction market, 2016 - 2027 (USD Million)
FIG. 47 Global long bone market, 2016 - 2027 (USD Million)
FIG. 48 Global spinal fusion market, 2016 - 2027 (USD Million)
FIG. 49 Regional market place: Key takeaways
FIG. 50 Regional outlook, 2019 & 2027
FIG. 51 North America bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 52 U.S. bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 53 Canada bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 54 Europe bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 55 U.K. bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 56 Germany bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 57 France bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 58 Italy bone graft and substitutes market, 2016 - 2027 (USD Million)
FIG. 59 Spain bone graft and substitutes market, 2016 - 2027 (USD Million)
FIG. 60 Asia Pacific bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 61 China bone graft and substitutes market, 2016 - 2027 (USD Million)
FIG. 62 Japan bone graft and substitutes market, 2016 - 2027 (USD Million)
FIG. 63 India bone graft and substitutes market, 2016 - 2027 (USD Million)
FIG. 64 South Korea bone graft and substitutes market, 2016 - 2027 (USD Million)
FIG. 65 Latin America bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 66 Mexico bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 67 Brazil bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 68 MEA bone grafts & substitutes market, 2016 - 2027 (USD Million)
FIG. 69 South Africa bone grafts & substitutes market, 2016 - 2027 (USD Million)"