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Published: Aug, 2016 | Pages:
147 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
B-Cell Chronic Lymphocytic Leukemia - Pipeline Review, H2 2016 Summary Global Markets Direct's, 'B-Cell Chronic Lymphocytic Leukemia - Pipeline Review, H2 2016', provides an overview of the B-Cell Chronic Lymphocytic Leukemia pipeline landscape. The report provides comprehensive information on the therapeutics under development for B-Cell Chronic Lymphocytic Leukemia, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for B-Cell Chronic Lymphocytic Leukemia and features dormant and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data. Scope - The report provides a snapshot of the global therapeutic landscape of B-Cell Chronic Lymphocytic Leukemia - The report reviews pipeline therapeutics for B-Cell Chronic Lymphocytic Leukemia by companies and universities/research institutes based on information derived from company and industry-specific sources - The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages - The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved B-Cell Chronic Lymphocytic Leukemia therapeutics and enlists all their major and minor projects - The report assesses B-Cell Chronic Lymphocytic Leukemia therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type - The report summarizes all the dormant and discontinued pipeline projects - The report reviews latest news related to pipeline therapeutics for B-Cell Chronic Lymphocytic Leukemia Reasons to buy - Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Identify and understand important and diverse types of therapeutics under development for B-Cell Chronic Lymphocytic Leukemia - Identify potential new clients or partners in the target demographic - Develop strategic initiatives by understanding the focus areas of leading companies - Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics - Devise corrective measures for pipeline projects by understanding B-Cell Chronic Lymphocytic Leukemia pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents
Table of Contents 2 List of Tables 7 List of Figures 8 Introduction 9 Global Markets Direct Report Coverage 9 B-Cell Chronic Lymphocytic Leukemia Overview 10 Therapeutics Development 11 Pipeline Products for B-Cell Chronic Lymphocytic Leukemia - Overview 11 Pipeline Products for B-Cell Chronic Lymphocytic Leukemia - Comparative Analysis 12 B-Cell Chronic Lymphocytic Leukemia - Therapeutics under Development by Companies 13 B-Cell Chronic Lymphocytic Leukemia - Therapeutics under Investigation by Universities/Institutes 15 B-Cell Chronic Lymphocytic Leukemia - Pipeline Products Glance 16 Late Stage Products 16 Clinical Stage Products 17 Early Stage Products 18 B-Cell Chronic Lymphocytic Leukemia - Products under Development by Companies 19 B-Cell Chronic Lymphocytic Leukemia - Products under Investigation by Universities/Institutes 21 B-Cell Chronic Lymphocytic Leukemia - Companies Involved in Therapeutics Development 22 AB Science SA 22 Aduro BioTech, Inc. 23 Amgen Inc. 24 Celgene Corporation 25 Cell Source, Inc. 26 Dynavax Technologies Corporation 27 Eisai Co., Ltd. 28 Elsalys Biotech SAS 29 F. Hoffmann-La Roche Ltd. 30 iDD biotech SAS 31 Immunomedics, Inc. 32 Johnson & Johnson 33 Juno Therapeutics Inc. 34 Lymphocyte Activation Technologies, S.A. 35 MedImmune, LLC 36 MEI Pharma, Inc. 37 Millennium Pharmaceuticals Inc 38 Molecular Templates Inc. 39 Noxxon Pharma AG 40 Ono Pharmaceutical Co., Ltd. 41 Regeneron Pharmaceuticals Inc 42 Sunesis Pharmaceuticals, Inc. 43 TheraMAB LLC 44 Unum Therapeutics, Inc. 45 B-Cell Chronic Lymphocytic Leukemia - Therapeutics Assessment 46 Assessment by Monotherapy Products 46 Assessment by Combination Products 47 Assessment by Target 48 Assessment by Mechanism of Action 50 Assessment by Route of Administration 52 Assessment by Molecule Type 54 Drug Profiles 56 202-b - Drug Profile 56 Product Description 56 Mechanism Of Action 56 R&D Progress 56 AB-8779 - Drug Profile 58 Product Description 58 Mechanism Of Action 58 R&D Progress 58 alemtuzumab biosimilar - Drug Profile 59 Product Description 59 Mechanism Of Action 59 R&D Progress 59 alisertib - Drug Profile 60 Product Description 60 Mechanism Of Action 60 R&D Progress 60 AMG-319 - Drug Profile 65 Product Description 65 Mechanism Of Action 65 R&D Progress 65 BB-001 - Drug Profile 67 Product Description 67 Mechanism Of Action 67 R&D Progress 67 BION-1301 - Drug Profile 68 Product Description 68 Mechanism Of Action 68 R&D Progress 68 Cellular Immunotherapy for Chronic Lymphocytic Leukaemia - Drug Profile 69 Product Description 69 Mechanism Of Action 69 R&D Progress 69 Cellular Immunotherapy for Hematological Malignancies - Drug Profile 70 Product Description 70 Mechanism Of Action 70 R&D Progress 70 Cellular Immunotherapy to Activate 4-1BBL and to Target CD19 for B-Cell Malignancies - Drug Profile 71 Product Description 71 Mechanism Of Action 71 R&D Progress 71 Cellular Immunotherapy to Activate CD40L and to Target CD19 for B-Cell Malignancies - Drug Profile 73 Product Description 73 Mechanism Of Action 73 R&D Progress 73 Cellular Immunotherapy to Activate IL-12 and to Target CD19 for B-Cell Malignancies - Drug Profile 75 Product Description 75 Mechanism Of Action 75 R&D Progress 75 Cellular Immunotherapy to Target CD16 for B-Cell Non-Hodgkin Lymphoma and B-Cell Chronic Lymphocytic Leukemia - Drug Profile 77 Product Description 77 Mechanism Of Action 77 R&D Progress 77 Cellular Immunotherapy to Target CD19 for B-Cell Chronic Lymphocytic Leukemia - Drug Profile 78 Product Description 78 Mechanism Of Action 78 R&D Progress 78 Cellular Immunotherapy to Target CD19 for B-Cell Malignancies - Drug Profile 79 Product Description 79 Mechanism Of Action 79 R&D Progress 79 Cellular Immunotherapy to Target CD19 for Oncology - Drug Profile 80 Product Description 80 Mechanism Of Action 80 R&D Progress 80 Cellular Immunotherapy to Target CD19 for Oncology - Drug Profile 81 Product Description 81 Mechanism Of Action 81 R&D Progress 81 Cellular Immunotherapy to Target CD19 for Oncology - Drug Profile 82 Product Description 82 Mechanism Of Action 82 R&D Progress 82 durvalumab - Drug Profile 83 Product Description 83 Mechanism Of Action 83 R&D Progress 83 E-7449 - Drug Profile 93 Product Description 93 Mechanism Of Action 93 R&D Progress 93 IDD-001 - Drug Profile 94 Product Description 94 Mechanism Of Action 94 R&D Progress 94 IDD-002 - Drug Profile 95 Product Description 95 Mechanism Of Action 95 R&D Progress 95 JNJ-64052781 - Drug Profile 96 Product Description 96 Mechanism Of Action 96 R&D Progress 96 lenalidomide - Drug Profile 98 Product Description 98 Mechanism Of Action 98 R&D Progress 98 MAT-303 - Drug Profile 112 Product Description 112 Mechanism Of Action 112 R&D Progress 112 ME-401 - Drug Profile 113 Product Description 113 Mechanism Of Action 113 R&D Progress 113 mRNA ACTR + rituximab - Drug Profile 115 Product Description 115 Mechanism Of Action 115 R&D Progress 115 MT-3724 - Drug Profile 117 Product Description 117 Mechanism Of Action 117 R&D Progress 117 olaptesed pegol - Drug Profile 119 Product Description 119 Mechanism Of Action 119 R&D Progress 119 ONO-4059 - Drug Profile 123 Product Description 123 Mechanism Of Action 123 R&D Progress 123 REGN-1979 - Drug Profile 125 Product Description 125 Mechanism Of Action 125 R&D Progress 125 SD-101 - Drug Profile 126 Product Description 126 Mechanism Of Action 126 R&D Progress 126 SNS-062 - Drug Profile 129 Product Description 129 Mechanism Of Action 129 R&D Progress 129 TAB-08 - Drug Profile 131 Product Description 131 Mechanism Of Action 131 R&D Progress 131 tocilizumab - Drug Profile 133 Product Description 133 Mechanism Of Action 133 R&D Progress 133 B-Cell Chronic Lymphocytic Leukemia - Dormant Projects 141 B-Cell Chronic Lymphocytic Leukemia - Discontinued Products 144 B-Cell Chronic Lymphocytic Leukemia - Product Development Milestones 145 Featured News & Press Releases 145 Apr 06, 2015: Juno Therapeutics Announces Patent Litigation Settlement 145 Nov 15, 2011: TheraMAB launches Phase I clinical trial of first-in-class agonistic monoclonal antibody TAB08 in Russia 145 Appendix 146 Methodology 146 Coverage 146 Secondary Research 146 Primary Research 146 Expert Panel Validation 146 Contact Us 146 Disclaimer 147
List of Tables
Number of Products under Development for B-Cell Chronic Lymphocytic Leukemia, H2 2016 11 Number of Products under Development for B-Cell Chronic Lymphocytic Leukemia - Comparative Analysis, H2 2016 12 Number of Products under Development by Companies, H2 2016 14 Number of Products under Investigation by Universities/Institutes, H2 2016 15 Comparative Analysis by Late Stage Development, H2 2016 16 Comparative Analysis by Clinical Stage Development, H2 2016 17 Comparative Analysis by Early Stage Development, H2 2016 18 Products under Development by Companies, H2 2016 19 Products under Development by Companies, H2 2016 (Contd..1) 20 Products under Investigation by Universities/Institutes, H2 2016 21 B-Cell Chronic Lymphocytic Leukemia - Pipeline by AB Science SA, H2 2016 22 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Aduro BioTech, Inc., H2 2016 23 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Amgen Inc., H2 2016 24 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Celgene Corporation, H2 2016 25 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Cell Source, Inc., H2 2016 26 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Dynavax Technologies Corporation, H2 2016 27 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Eisai Co., Ltd., H2 2016 28 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Elsalys Biotech SAS, H2 2016 29 B-Cell Chronic Lymphocytic Leukemia - Pipeline by F. Hoffmann-La Roche Ltd., H2 2016 30 B-Cell Chronic Lymphocytic Leukemia - Pipeline by iDD biotech SAS, H2 2016 31 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Immunomedics, Inc., H2 2016 32 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Johnson & Johnson, H2 2016 33 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Juno Therapeutics Inc., H2 2016 34 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Lymphocyte Activation Technologies, S.A., H2 2016 35 B-Cell Chronic Lymphocytic Leukemia - Pipeline by MedImmune, LLC, H2 2016 36 B-Cell Chronic Lymphocytic Leukemia - Pipeline by MEI Pharma, Inc., H2 2016 37 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Millennium Pharmaceuticals Inc, H2 2016 38 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Molecular Templates Inc., H2 2016 39 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Noxxon Pharma AG, H2 2016 40 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Ono Pharmaceutical Co., Ltd., H2 2016 41 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Regeneron Pharmaceuticals Inc, H2 2016 42 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Sunesis Pharmaceuticals, Inc., H2 2016 43 B-Cell Chronic Lymphocytic Leukemia - Pipeline by TheraMAB LLC, H2 2016 44 B-Cell Chronic Lymphocytic Leukemia - Pipeline by Unum Therapeutics, Inc., H2 2016 45 Assessment by Monotherapy Products, H2 2016 46 Assessment by Combination Products, H2 2016 47 Number of Products by Stage and Target, H2 2016 49 Number of Products by Stage and Mechanism of Action, H2 2016 51 Number of Products by Stage and Route of Administration, H2 2016 53 Number of Products by Stage and Molecule Type, H2 2016 55 B-Cell Chronic Lymphocytic Leukemia - Dormant Projects, H2 2016 141 B-Cell Chronic Lymphocytic Leukemia - Dormant Projects (Contd..1), H2 2016 142 B-Cell Chronic Lymphocytic Leukemia - Dormant Projects (Contd..2), H2 2016 143 B-Cell Chronic Lymphocytic Leukemia - Discontinued Products, H2 2016 144
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