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Published: May, 2017 | Pages:
79 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Aplastic Anemia - Pipeline Review, H1 2017 Summary Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Aplastic Anemia - Pipeline Review, H1 2017, provides an overview of the Aplastic Anemia (Hematological Disorders) pipeline landscape. Aplastic anemia is a syndrome of bone marrow failure characterized by peripheral pancytopenia and marrow hypoplasia. Symptoms include fatigue, pale skin, rapid or irregular heart rate, shortness of breath with exertion, nosebleeds and bleeding gums, prolonged bleeding from cuts, skin rash, dizziness and headache. Risk factors include exposure to toxic chemicals, treatment with high-dose radiation or chemotherapy for cancer, certain blood diseases, autoimmune disorders and serious infections. Treatment includes immunosuppressants and stem cell transplant. Report Highlights Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Aplastic Anemia - Pipeline Review, H1 2017, provides comprehensive information on the therapeutics under development for Aplastic Anemia (Hematological Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. The Aplastic Anemia (Hematological Disorders) pipeline guide also reviews of key players involved in therapeutic development for Aplastic Anemia and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, IND/CTA Filed and Preclinical stages are 2, 2, 1, 1 and 5 respectively. Aplastic Anemia (Hematological Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data. Scope - The pipeline guide provides a snapshot of the global therapeutic landscape of Aplastic Anemia (Hematological Disorders). - The pipeline guide reviews pipeline therapeutics for Aplastic Anemia (Hematological Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources. - The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages. - The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities. - The pipeline guide reviews key companies involved in Aplastic Anemia (Hematological Disorders) therapeutics and enlists all their major and minor projects. - The pipeline guide evaluates Aplastic Anemia (Hematological Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. - The pipeline guide encapsulates all the dormant and discontinued pipeline projects. - The pipeline guide reviews latest news related to pipeline therapeutics for Aplastic Anemia (Hematological Disorders) Reasons To Buy - Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies. - Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage. - Find and recognize significant and varied types of therapeutics under development for Aplastic Anemia (Hematological Disorders). - Classify potential new clients or partners in the target demographic. - Develop tactical initiatives by understanding the focus areas of leading companies. - Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics. - Formulate corrective measures for pipeline projects by understanding Aplastic Anemia (Hematological Disorders) pipeline depth and focus of Indication therapeutics. - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope. - Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
Table of Contents
List of Tables List of Figures Introduction Global Markets Direct Report Coverage Aplastic Anemia - Overview Aplastic Anemia - Therapeutics Development Pipeline Overview Pipeline by Companies Products under Development by Companies Aplastic Anemia - Therapeutics Assessment Assessment by Target Assessment by Mechanism of Action Assessment by Route of Administration Assessment by Molecule Type Aplastic Anemia - Companies Involved in Therapeutics Development 3SBio Inc Acceleron Pharma Inc Amgen Inc BioLineRx Ltd F. Hoffmann-La Roche Ltd Gamida Cell Ltd Novartis AG Pluristem Therapeutics Inc Regen BioPharma Inc Aplastic Anemia - Drug Profiles Anemir - Drug Profile Product Description Mechanism Of Action R&D Progress BL-8040 - Drug Profile Product Description Mechanism Of Action R&D Progress Cell Therapy for Aplastic Anemia - Drug Profile Product Description Mechanism Of Action R&D Progress CordIn - Drug Profile Product Description Mechanism Of Action R&D Progress eltrombopag olamine - Drug Profile Product Description Mechanism Of Action R&D Progress Gene Therapy to Activate Telomerase for Aplastic Anemia - Drug Profile Product Description Mechanism Of Action R&D Progress HemaXellerate - Drug Profile Product Description Mechanism Of Action R&D Progress PLXR-18 - Drug Profile Product Description Mechanism Of Action R&D Progress romiplostim - Drug Profile Product Description Mechanism Of Action R&D Progress sotatercept - Drug Profile Product Description Mechanism Of Action R&D Progress thrombopoietin - Drug Profile Product Description Mechanism Of Action R&D Progress Aplastic Anemia - Dormant Projects Aplastic Anemia - Discontinued Products Aplastic Anemia - Product Development Milestones Featured News & Press Releases Apr 20, 2017: NIH study in NEJM shows Novartis drug eltrombopag as first-line therapy with standard treatment improves responses in severe aplastic anemia Oct 24, 2016: Pan Am Cancer Treatment Center Provides Final HemaXellerate Clinical Data to Regen BioPharma, for treatment of Bone Marrow Suppression Study Sep 22, 2016: Regen BioPharma Responds to FDA Comments on Its Application for Orphan Drug Designation on its Aplastic Anemia Therapy Aug 25, 2016: Health Canada issues advisory on REVOLADE citing risk of severe hepatotoxicity May 11, 2016: Regen BioPharma Discusses Recent Developments in Aplastic Anemia Therapy and Future Potential Expansion of HemaXellerate May 03, 2016: Regen BioPharma Receives Preliminary Clinical Data from Pan Am Cancer Center Regarding Their HemaXellerate Study in Cancer Patients Jan 26, 2016: Regen BioPharma Submits Application to FDA for Orphan Drug Designation for its HemaXellerate Product Dec 15, 2015: Regen BioPharma Receives FDA Clearance to Initiate Clinical Trial of HemaXellerate Nov 23, 2015: BioLineRx Announces Initiation of Phase 1/2 Trial for Novel Treatment in Two Bone Marrow Failure Conditions Nov 17, 2015: Regen BioPharma Submits Response to FDA Questions on HemaXellerate Investigational New Drug Application Nov 17, 2015: Pluristem to Present New Data on PLX-R18 at American Society of Hematology's Annual Meeting Sep 25, 2015: Regen BioPharma Announces Positive Results from GLP Safety Study for HemaXellerate Sep 10, 2015: BioLineRx Announces Regulatory Submission for Phase 2 Trial of BL-8040 as Novel Treatment for Hypoplastic Myelodysplastic Syndrome and Aplastic Anemia Sep 02, 2015: Novartis receives EU approval for new Revolade use as first-in-class therapy for patients with severe aplastic anemia Jul 24, 2015: Novartis drug Revolade recommended by CHMP for EU approval to treat patients with severe aplastic anemia, a serious blood disorder Appendix Methodology Coverage Secondary Research Primary Research Expert Panel Validation Contact Us Disclaimer
List of Tables
Number of Products under Development for Aplastic Anemia, H1 2017 Number of Products under Development by Companies, H1 2017 Products under Development by Companies, H1 2017 Number of Products by Stage and Target, H1 2017 Number of Products by Stage and Mechanism of Action, H1 2017 Number of Products by Stage and Route of Administration, H1 2017 Number of Products by Stage and Molecule Type, H1 2017 Aplastic Anemia - Pipeline by 3SBio Inc, H1 2017 Aplastic Anemia - Pipeline by Acceleron Pharma Inc, H1 2017 Aplastic Anemia - Pipeline by Amgen Inc, H1 2017 Aplastic Anemia - Pipeline by BioLineRx Ltd, H1 2017 Aplastic Anemia - Pipeline by F. Hoffmann-La Roche Ltd, H1 2017 Aplastic Anemia - Pipeline by Gamida Cell Ltd, H1 2017 Aplastic Anemia - Pipeline by Novartis AG, H1 2017 Aplastic Anemia - Pipeline by Pluristem Therapeutics Inc, H1 2017 Aplastic Anemia - Pipeline by Regen BioPharma Inc, H1 2017 Aplastic Anemia - Dormant Projects, H1 2017 Aplastic Anemia - Discontinued Products, H1 2017
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